Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | GMP.GMP.mono_Pheno.cls #Group1_versus_Group3.GMP.mono_Pheno.cls #Group1_versus_Group3_repos |
| Phenotype | GMP.mono_Pheno.cls#Group1_versus_Group3_repos |
| Upregulated in class | 2 |
| GeneSet | HALLMARK_WNT_BETA_CATENIN_SIGNALING |
| Enrichment Score (ES) | -0.42563462 |
| Normalized Enrichment Score (NES) | -1.2809608 |
| Nominal p-value | 0.19723865 |
| FDR q-value | 0.5405993 |
| FWER p-Value | 0.8 |
| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Jag1 | 1572 | 0.400 | -0.0151 | No |
| 2 | Hdac5 | 4539 | 0.217 | -0.1128 | No |
| 3 | Maml1 | 5009 | 0.198 | -0.1071 | No |
| 4 | Axin2 | 5113 | 0.194 | -0.0865 | No |
| 5 | Cul1 | 5265 | 0.190 | -0.0684 | No |
| 6 | Ncor2 | 5387 | 0.185 | -0.0497 | No |
| 7 | Lef1 | 6108 | 0.157 | -0.0600 | No |
| 8 | Rbpj | 6908 | 0.130 | -0.0770 | No |
| 9 | Frat1 | 7737 | 0.106 | -0.0985 | No |
| 10 | Hdac2 | 8363 | 0.088 | -0.1137 | No |
| 11 | Adam17 | 8602 | 0.080 | -0.1134 | No |
| 12 | Skp2 | 8699 | 0.077 | -0.1075 | No |
| 13 | Ctnnb1 | 9654 | 0.048 | -0.1417 | No |
| 14 | Nkd1 | 9904 | 0.041 | -0.1469 | No |
| 15 | Numb | 10206 | 0.032 | -0.1556 | No |
| 16 | Fzd1 | 10800 | 0.015 | -0.1788 | No |
| 17 | Dvl2 | 10919 | 0.011 | -0.1824 | No |
| 18 | Kat2a | 12259 | -0.025 | -0.2359 | No |
| 19 | Hdac11 | 13045 | -0.048 | -0.2631 | No |
| 20 | Notch4 | 13328 | -0.057 | -0.2678 | No |
| 21 | Axin1 | 14032 | -0.078 | -0.2875 | No |
| 22 | Ppard | 14786 | -0.102 | -0.3062 | No |
| 23 | Trp53 | 14982 | -0.110 | -0.3003 | No |
| 24 | Notch1 | 15690 | -0.134 | -0.3130 | No |
| 25 | Psen2 | 15782 | -0.137 | -0.2993 | No |
| 26 | Gnai1 | 15952 | -0.143 | -0.2880 | No |
| 27 | Ncstn | 16804 | -0.172 | -0.3020 | No |
| 28 | Ccnd2 | 19722 | -0.293 | -0.3879 | Yes |
| 29 | Tcf7 | 19741 | -0.294 | -0.3507 | Yes |
| 30 | Wnt5b | 20023 | -0.309 | -0.3228 | Yes |
| 31 | Csnk1e | 20427 | -0.331 | -0.2972 | Yes |
| 32 | Ptch1 | 21463 | -0.399 | -0.2898 | Yes |
| 33 | Jag2 | 21473 | -0.399 | -0.2387 | Yes |
| 34 | Fzd8 | 22471 | -0.496 | -0.2171 | Yes |
| 35 | Myc | 22987 | -0.581 | -0.1641 | Yes |
| 36 | Wnt1 | 23148 | -0.623 | -0.0907 | Yes |
| 37 | Wnt6 | 23538 | -0.860 | 0.0036 | Yes |
