Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Mast.Mast_Pheno.cls #Group6_versus_Group8.Mast_Pheno.cls #Group6_versus_Group8_repos |
| Phenotype | Mast_Pheno.cls#Group6_versus_Group8_repos |
| Upregulated in class | 5 |
| GeneSet | HALLMARK_IL6_JAK_STAT3_SIGNALING |
| Enrichment Score (ES) | -0.20753914 |
| Normalized Enrichment Score (NES) | -0.7735988 |
| Nominal p-value | 0.7909836 |
| FDR q-value | 0.9181442 |
| FWER p-Value | 1.0 |
| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Tnfrsf1b | 232 | 0.709 | 0.0304 | Yes |
| 2 | Ltbr | 300 | 0.663 | 0.0710 | Yes |
| 3 | Pf4 | 410 | 0.614 | 0.1048 | Yes |
| 4 | Ifnar1 | 918 | 0.461 | 0.0959 | Yes |
| 5 | Bak1 | 919 | 0.461 | 0.1279 | Yes |
| 6 | Il9r | 1121 | 0.435 | 0.1418 | Yes |
| 7 | Il12rb1 | 1267 | 0.413 | 0.1587 | Yes |
| 8 | Hax1 | 1289 | 0.412 | 0.1856 | Yes |
| 9 | Il18r1 | 1594 | 0.367 | 0.1865 | Yes |
| 10 | Il15ra | 1737 | 0.346 | 0.1990 | Yes |
| 11 | Irf1 | 2338 | 0.283 | 0.1702 | No |
| 12 | Pik3r5 | 3070 | 0.230 | 0.1271 | No |
| 13 | Tnf | 3696 | 0.180 | 0.0891 | No |
| 14 | Ptpn11 | 4127 | 0.146 | 0.0646 | No |
| 15 | Jun | 4385 | 0.126 | 0.0525 | No |
| 16 | Il1r1 | 4585 | 0.110 | 0.0441 | No |
| 17 | Csf3r | 4587 | 0.110 | 0.0516 | No |
| 18 | Cbl | 4787 | 0.094 | 0.0421 | No |
| 19 | Acvr1b | 4790 | 0.094 | 0.0484 | No |
| 20 | Stat1 | 4881 | 0.087 | 0.0472 | No |
| 21 | Pim1 | 4961 | 0.081 | 0.0465 | No |
| 22 | Il4ra | 5072 | 0.073 | 0.0426 | No |
| 23 | Cd44 | 6085 | 0.002 | -0.0389 | No |
| 24 | Tgfb1 | 6845 | -0.030 | -0.0981 | No |
| 25 | Itgb3 | 6870 | -0.031 | -0.0979 | No |
| 26 | Il2rg | 6957 | -0.038 | -0.1022 | No |
| 27 | Grb2 | 7052 | -0.043 | -0.1068 | No |
| 28 | Tnfrsf21 | 7368 | -0.061 | -0.1280 | No |
| 29 | Il3ra | 7382 | -0.062 | -0.1248 | No |
| 30 | Il6 | 8050 | -0.108 | -0.1712 | No |
| 31 | Il6st | 8165 | -0.115 | -0.1724 | No |
| 32 | Itga4 | 8177 | -0.116 | -0.1652 | No |
| 33 | Stam2 | 8595 | -0.147 | -0.1886 | No |
| 34 | Tyk2 | 8830 | -0.164 | -0.1962 | No |
| 35 | Il17rb | 8967 | -0.176 | -0.1949 | No |
| 36 | Csf1 | 9079 | -0.184 | -0.1911 | No |
| 37 | Il17ra | 9246 | -0.197 | -0.1909 | No |
| 38 | Ptpn2 | 9314 | -0.202 | -0.1823 | No |
| 39 | Crlf2 | 9437 | -0.211 | -0.1775 | No |
| 40 | Ptpn1 | 9505 | -0.218 | -0.1678 | No |
| 41 | Ifngr1 | 9513 | -0.219 | -0.1532 | No |
| 42 | Stat2 | 9579 | -0.224 | -0.1429 | No |
| 43 | Ccr1 | 9703 | -0.236 | -0.1364 | No |
| 44 | Il10rb | 9781 | -0.243 | -0.1258 | No |
| 45 | Il7 | 10178 | -0.267 | -0.1392 | No |
| 46 | Cd9 | 10498 | -0.298 | -0.1443 | No |
| 47 | Irf9 | 10939 | -0.346 | -0.1558 | No |
| 48 | Tnfrsf1a | 11577 | -0.438 | -0.1769 | No |
| 49 | Il1r2 | 11724 | -0.464 | -0.1565 | No |
| 50 | Ltb | 11794 | -0.474 | -0.1292 | No |
| 51 | Stat3 | 11885 | -0.497 | -0.1020 | No |
| 52 | Csf2ra | 12155 | -0.594 | -0.0825 | No |
| 53 | Myd88 | 12262 | -0.663 | -0.0451 | No |
| 54 | Ifngr2 | 12406 | -0.857 | 0.0028 | No |
