| Dataset | Mast.Mast_Pheno.cls #Group6_versus_Group8.Mast_Pheno.cls #Group6_versus_Group8_repos |
| Phenotype | Mast_Pheno.cls#Group6_versus_Group8_repos |
| Upregulated in class | 5 |
| GeneSet | HALLMARK_G2M_CHECKPOINT |
| Enrichment Score (ES) | -0.22974057 |
| Normalized Enrichment Score (NES) | -0.91119176 |
| Nominal p-value | 0.5917526 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Map3k20 | 136 | 0.801 | 0.0061 | No |
| 2 | Ddx39a | 289 | 0.671 | 0.0080 | No |
| 3 | G3bp1 | 295 | 0.666 | 0.0219 | No |
| 4 | Ilf3 | 339 | 0.634 | 0.0320 | No |
| 5 | Dkc1 | 671 | 0.529 | 0.0163 | No |
| 6 | Myc | 692 | 0.522 | 0.0259 | No |
| 7 | Ss18 | 728 | 0.508 | 0.0339 | No |
| 8 | Ezh2 | 769 | 0.495 | 0.0412 | No |
| 9 | E2f1 | 789 | 0.491 | 0.0502 | No |
| 10 | Lig3 | 900 | 0.463 | 0.0512 | No |
| 11 | Fancc | 1037 | 0.444 | 0.0496 | No |
| 12 | Notch2 | 1122 | 0.435 | 0.0520 | No |
| 13 | Slc12a2 | 1251 | 0.415 | 0.0505 | No |
| 14 | Mcm5 | 1401 | 0.400 | 0.0469 | No |
| 15 | Nolc1 | 1583 | 0.369 | 0.0400 | No |
| 16 | Hira | 1653 | 0.358 | 0.0421 | No |
| 17 | Mnat1 | 1692 | 0.353 | 0.0465 | No |
| 18 | Dbf4 | 1782 | 0.341 | 0.0466 | No |
| 19 | Meis1 | 1810 | 0.337 | 0.0516 | No |
| 20 | Racgap1 | 1818 | 0.336 | 0.0582 | No |
| 21 | Tnpo2 | 1918 | 0.325 | 0.0571 | No |
| 22 | Rbl1 | 1950 | 0.321 | 0.0615 | No |
| 23 | Traip | 1964 | 0.319 | 0.0672 | No |
| 24 | Sqle | 1971 | 0.319 | 0.0736 | No |
| 25 | Odc1 | 2042 | 0.312 | 0.0746 | No |
| 26 | Odf2 | 2065 | 0.309 | 0.0794 | No |
| 27 | Dr1 | 2103 | 0.305 | 0.0829 | No |
| 28 | Bard1 | 2360 | 0.281 | 0.0681 | No |
| 29 | Marcks | 2642 | 0.262 | 0.0507 | No |
| 30 | Mcm2 | 2663 | 0.260 | 0.0547 | No |
| 31 | Syncrip | 2679 | 0.259 | 0.0590 | No |
| 32 | Aurkb | 2686 | 0.259 | 0.0641 | No |
| 33 | Bub3 | 2864 | 0.250 | 0.0550 | No |
| 34 | Nup98 | 3018 | 0.234 | 0.0475 | No |
| 35 | Mcm6 | 3069 | 0.230 | 0.0483 | No |
| 36 | Amd1 | 3258 | 0.219 | 0.0377 | No |
| 37 | Cdc25a | 3276 | 0.217 | 0.0409 | No |
| 38 | Slc7a5 | 3286 | 0.215 | 0.0448 | No |
| 39 | Nasp | 3336 | 0.210 | 0.0453 | No |
| 40 | Plk4 | 3392 | 0.206 | 0.0453 | No |
| 41 | Hnrnpu | 3410 | 0.204 | 0.0482 | No |
| 42 | Hnrnpd | 3490 | 0.197 | 0.0460 | No |
| 43 | Abl1 | 3585 | 0.188 | 0.0424 | No |
| 44 | Cul5 | 3709 | 0.179 | 0.0362 | No |
| 45 | Cul3 | 3765 | 0.175 | 0.0354 | No |
| 46 | Stil | 3825 | 0.171 | 0.0343 | No |
| 47 | Hus1 | 3918 | 0.164 | 0.0303 | No |
| 48 | Dmd | 3989 | 0.158 | 0.0279 | No |
| 49 | Cks1b | 4026 | 0.155 | 0.0283 | No |
| 50 | Cdc45 | 4192 | 0.141 | 0.0179 | No |
| 51 | Plk1 | 4228 | 0.138 | 0.0180 | No |
| 52 | Smc2 | 4276 | 0.135 | 0.0171 | No |
| 53 | Cdkn1b | 4283 | 0.135 | 0.0195 | No |
| 54 | Prmt5 | 4367 | 0.127 | 0.0154 | No |
| 55 | Arid4a | 4464 | 0.119 | 0.0101 | No |
| 56 | Srsf1 | 4469 | 0.119 | 0.0123 | No |
| 57 | Kpnb1 | 4475 | 0.118 | 0.0145 | No |
| 58 | Srsf2 | 4519 | 0.115 | 0.0134 | No |
| 59 | Rasal2 | 4595 | 0.109 | 0.0096 | No |
| 60 | Numa1 | 4628 | 0.107 | 0.0093 | No |
| 61 | Kif5b | 4766 | 0.096 | 0.0002 | No |
| 62 | Prpf4b | 4792 | 0.094 | 0.0001 | No |
| 63 | Casp8ap2 | 4862 | 0.089 | -0.0036 | No |
| 64 | Wrn | 4877 | 0.088 | -0.0028 | No |
| 65 | Nsd2 | 4907 | 0.086 | -0.0034 | No |
| 66 | Cdc7 | 4966 | 0.081 | -0.0064 | No |
| 67 | Upf1 | 5033 | 0.076 | -0.0101 | No |
| 68 | Lbr | 5071 | 0.073 | -0.0116 | No |
| 69 | Ttk | 5244 | 0.061 | -0.0243 | No |
| 70 | Mapk14 | 5259 | 0.060 | -0.0242 | No |
| 71 | Rad21 | 5269 | 0.059 | -0.0237 | No |
| 72 | Pml | 5355 | 0.052 | -0.0295 | No |
| 73 | Chmp1a | 5465 | 0.045 | -0.0374 | No |
| 74 | E2f2 | 5629 | 0.034 | -0.0500 | No |
| 75 | Pole | 5908 | 0.013 | -0.0724 | No |
| 76 | Cdc20 | 6019 | 0.007 | -0.0812 | No |
| 77 | Nusap1 | 6517 | -0.010 | -0.1216 | No |
| 78 | Mcm3 | 6809 | -0.028 | -0.1447 | No |
| 79 | Kmt5a | 6832 | -0.029 | -0.1459 | No |
| 80 | Slc7a1 | 6844 | -0.030 | -0.1461 | No |
| 81 | Tgfb1 | 6845 | -0.030 | -0.1455 | No |
| 82 | Ube2s | 6899 | -0.033 | -0.1491 | No |
| 83 | Incenp | 6932 | -0.036 | -0.1509 | No |
| 84 | H2az2 | 6973 | -0.039 | -0.1534 | No |
| 85 | Fbxo5 | 7053 | -0.043 | -0.1589 | No |
| 86 | H2ax | 7189 | -0.052 | -0.1688 | No |
| 87 | Tent4a | 7240 | -0.055 | -0.1717 | No |
| 88 | E2f4 | 7287 | -0.057 | -0.1742 | No |
| 89 | Cul4a | 7309 | -0.058 | -0.1747 | No |
| 90 | Mybl2 | 7355 | -0.060 | -0.1771 | No |
| 91 | Cks2 | 7387 | -0.062 | -0.1783 | No |
| 92 | Xpo1 | 7466 | -0.067 | -0.1832 | No |
| 93 | Orc6 | 7568 | -0.074 | -0.1899 | No |
| 94 | Tfdp1 | 7668 | -0.081 | -0.1962 | No |
| 95 | Sfpq | 7690 | -0.082 | -0.1962 | No |
| 96 | Sap30 | 7701 | -0.083 | -0.1952 | No |
| 97 | Rad23b | 7791 | -0.089 | -0.2006 | No |
| 98 | E2f3 | 7802 | -0.090 | -0.1994 | No |
| 99 | Mad2l1 | 7837 | -0.093 | -0.2002 | No |
| 100 | Pola2 | 7843 | -0.094 | -0.1986 | No |
| 101 | Mtf2 | 7998 | -0.104 | -0.2090 | No |
| 102 | Smad3 | 8009 | -0.105 | -0.2075 | No |
| 103 | Snrpd1 | 8086 | -0.110 | -0.2114 | No |
| 104 | Bub1 | 8099 | -0.111 | -0.2100 | No |
| 105 | Cenpa | 8149 | -0.114 | -0.2115 | No |
| 106 | Uck2 | 8214 | -0.119 | -0.2142 | No |
| 107 | Jpt1 | 8253 | -0.122 | -0.2147 | No |
| 108 | Troap | 8259 | -0.123 | -0.2125 | No |
| 109 | Atrx | 8281 | -0.124 | -0.2115 | No |
| 110 | Top1 | 8315 | -0.127 | -0.2115 | No |
| 111 | Tra2b | 8392 | -0.132 | -0.2149 | No |
| 112 | Tacc3 | 8424 | -0.135 | -0.2145 | No |
| 113 | Hif1a | 8469 | -0.138 | -0.2151 | No |
| 114 | Stmn1 | 8512 | -0.141 | -0.2155 | No |
| 115 | Mki67 | 8533 | -0.143 | -0.2141 | No |
| 116 | Nup50 | 8627 | -0.149 | -0.2185 | No |
| 117 | Ncl | 8643 | -0.150 | -0.2165 | No |
| 118 | Egf | 8660 | -0.151 | -0.2146 | No |
| 119 | Atf5 | 8748 | -0.158 | -0.2183 | No |
| 120 | Smc1a | 8801 | -0.162 | -0.2191 | No |
| 121 | Foxn3 | 8851 | -0.166 | -0.2195 | No |
| 122 | Smc4 | 8854 | -0.166 | -0.2161 | No |
| 123 | Chek1 | 8891 | -0.169 | -0.2155 | No |
| 124 | Gspt1 | 8907 | -0.170 | -0.2130 | No |
| 125 | Top2a | 8923 | -0.172 | -0.2106 | No |
| 126 | Exo1 | 9001 | -0.178 | -0.2130 | No |
| 127 | Cdk1 | 9037 | -0.180 | -0.2120 | No |
| 128 | Rpa2 | 9047 | -0.181 | -0.2089 | No |
| 129 | Kif23 | 9178 | -0.192 | -0.2154 | No |
| 130 | Hspa8 | 9182 | -0.192 | -0.2115 | No |
| 131 | Katna1 | 9275 | -0.199 | -0.2147 | No |
| 132 | Cdk4 | 9360 | -0.206 | -0.2172 | No |
| 133 | Cdkn3 | 9515 | -0.219 | -0.2251 | Yes |
| 134 | Stag1 | 9527 | -0.220 | -0.2212 | Yes |
| 135 | Prc1 | 9564 | -0.223 | -0.2194 | Yes |
| 136 | Ccnt1 | 9587 | -0.225 | -0.2164 | Yes |
| 137 | Rad54l | 9622 | -0.228 | -0.2143 | Yes |
| 138 | Ctcf | 9635 | -0.229 | -0.2104 | Yes |
| 139 | Tmpo | 9646 | -0.230 | -0.2062 | Yes |
| 140 | Kif22 | 9654 | -0.231 | -0.2019 | Yes |
| 141 | Ndc80 | 9656 | -0.231 | -0.1970 | Yes |
| 142 | Pafah1b1 | 9673 | -0.233 | -0.1933 | Yes |
| 143 | Pura | 9723 | -0.238 | -0.1922 | Yes |
| 144 | Orc5 | 9761 | -0.241 | -0.1900 | Yes |
| 145 | Ccnf | 9941 | -0.254 | -0.1992 | Yes |
| 146 | Pds5b | 10009 | -0.260 | -0.1991 | Yes |
| 147 | Knl1 | 10040 | -0.264 | -0.1959 | Yes |
| 148 | Birc5 | 10047 | -0.265 | -0.1907 | Yes |
| 149 | Pbk | 10048 | -0.265 | -0.1851 | Yes |
| 150 | Gins2 | 10083 | -0.266 | -0.1821 | Yes |
| 151 | Kif15 | 10223 | -0.268 | -0.1877 | Yes |
| 152 | Slc38a1 | 10253 | -0.270 | -0.1843 | Yes |
| 153 | Tle3 | 10270 | -0.272 | -0.1798 | Yes |
| 154 | Cul1 | 10371 | -0.284 | -0.1818 | Yes |
| 155 | Chaf1a | 10374 | -0.284 | -0.1759 | Yes |
| 156 | Dtymk | 10505 | -0.298 | -0.1801 | Yes |
| 157 | Kif20b | 10506 | -0.298 | -0.1737 | Yes |
| 158 | Lmnb1 | 10512 | -0.299 | -0.1677 | Yes |
| 159 | Cenpf | 10605 | -0.310 | -0.1686 | Yes |
| 160 | Hmmr | 10619 | -0.312 | -0.1630 | Yes |
| 161 | Nek2 | 10742 | -0.323 | -0.1660 | Yes |
| 162 | Ythdc1 | 10753 | -0.323 | -0.1599 | Yes |
| 163 | Cdc25b | 10755 | -0.324 | -0.1530 | Yes |
| 164 | Ewsr1 | 11007 | -0.350 | -0.1660 | Yes |
| 165 | Bcl3 | 11217 | -0.377 | -0.1750 | Yes |
| 166 | Kif11 | 11284 | -0.387 | -0.1721 | Yes |
| 167 | Ccnb2 | 11343 | -0.395 | -0.1684 | Yes |
| 168 | Tpx2 | 11438 | -0.411 | -0.1672 | Yes |
| 169 | Ccna2 | 11559 | -0.434 | -0.1677 | Yes |
| 170 | Cdc27 | 11608 | -0.445 | -0.1621 | Yes |
| 171 | Ube2c | 11616 | -0.447 | -0.1531 | Yes |
| 172 | Kif2c | 11672 | -0.455 | -0.1478 | Yes |
| 173 | Srsf10 | 11787 | -0.472 | -0.1470 | Yes |
| 174 | Espl1 | 11798 | -0.474 | -0.1377 | Yes |
| 175 | Cdkn2c | 11806 | -0.474 | -0.1281 | Yes |
| 176 | Prim2 | 11827 | -0.477 | -0.1195 | Yes |
| 177 | Suv39h1 | 11905 | -0.502 | -0.1150 | Yes |
| 178 | Hmgb3 | 11952 | -0.515 | -0.1077 | Yes |
| 179 | Smarcc1 | 12030 | -0.542 | -0.1024 | Yes |
| 180 | Cbx1 | 12042 | -0.546 | -0.0916 | Yes |
| 181 | Aurka | 12095 | -0.568 | -0.0837 | Yes |
| 182 | Cenpe | 12102 | -0.570 | -0.0719 | Yes |
| 183 | H2az1 | 12120 | -0.579 | -0.0609 | Yes |
| 184 | Brca2 | 12165 | -0.597 | -0.0517 | Yes |
| 185 | Rps6ka5 | 12175 | -0.601 | -0.0396 | Yes |
| 186 | Pttg1 | 12277 | -0.671 | -0.0334 | Yes |
| 187 | Polq | 12287 | -0.677 | -0.0196 | Yes |
| 188 | Cdc6 | 12315 | -0.702 | -0.0068 | Yes |
| 189 | Kif4 | 12381 | -0.793 | 0.0049 | Yes |

