Details for gene set HALLMARK_E2F

Table: GSEA Results Summary

Dataset	Mast.Mast_Pheno.cls #Group6_versus_Group8.Mast_Pheno.cls #Group6_versus_Group8_repos
Phenotype	Mast_Pheno.cls#Group6_versus_Group8_repos
Upregulated in class	5
GeneSet	HALLMARK_E2F_TARGETS
Enrichment Score (ES)	-0.25122064
Normalized Enrichment Score (NES)	-0.90444976
Nominal p-value	0.59387755
FDR q-value	1.0
FWER p-Value	1.0

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Xrcc6	82	0.870	0.0116	No
2	Mthfd2	208	0.730	0.0168	No
3	Ddx39a	289	0.671	0.0244	No
4	Ilf3	339	0.634	0.0337	No
5	Nop56	365	0.624	0.0449	No
6	Pole4	444	0.603	0.0512	No
7	Anp32e	577	0.560	0.0522	No
8	Myc	692	0.522	0.0539	No
9	Ezh2	769	0.495	0.0581	No
10	Dctpp1	780	0.493	0.0677	No
11	Rad51ap1	960	0.456	0.0627	No
12	Ung	1159	0.428	0.0555	No
13	Mcm5	1401	0.400	0.0443	No
14	Cse1l	1412	0.397	0.0518	No
15	Nolc1	1583	0.369	0.0457	No
16	Pold3	1587	0.368	0.0532	No
17	Tbrg4	1643	0.361	0.0563	No
18	Prps1	1757	0.345	0.0544	No
19	Pcna	1792	0.339	0.0587	No
20	Racgap1	1818	0.336	0.0638	No
21	Pold1	2015	0.315	0.0544	No
22	Pop7	2088	0.307	0.0550	No
23	Msh2	2124	0.302	0.0585	No
24	Bard1	2360	0.281	0.0452	No
25	Slbp	2363	0.280	0.0510	No
26	Gins1	2420	0.277	0.0522	No
27	Nap1l1	2498	0.274	0.0517	No
28	Mcm2	2663	0.260	0.0438	No
29	Syncrip	2679	0.259	0.0480	No
30	Asf1b	2682	0.259	0.0533	No
31	Aurkb	2686	0.259	0.0585	No
32	Rfc3	2835	0.253	0.0518	No
33	Ipo7	3051	0.231	0.0391	No
34	Mcm6	3069	0.230	0.0425	No
35	Ppp1r8	3221	0.221	0.0349	No
36	Cdc25a	3276	0.217	0.0350	No
37	Nasp	3336	0.210	0.0346	No
38	Plk4	3392	0.206	0.0345	No
39	Cbx5	3414	0.203	0.0370	No
40	Hnrnpd	3490	0.197	0.0351	No
41	Smc6	3631	0.185	0.0275	No
42	Shmt1	3779	0.174	0.0192	No
43	Nudt21	3851	0.169	0.0170	No
44	Snrpb	3898	0.165	0.0167	No
45	Hus1	3918	0.164	0.0186	No
46	Psip1	3921	0.163	0.0218	No
47	Ccp110	3962	0.160	0.0220	No
48	Phf5a	3972	0.159	0.0246	No
49	Cks1b	4026	0.155	0.0235	No
50	Ranbp1	4035	0.154	0.0261	No
51	Lyar	4112	0.148	0.0230	No
52	Plk1	4228	0.138	0.0165	No
53	Pan2	4236	0.138	0.0189	No
54	Cdkn1a	4252	0.137	0.0205	No
55	Cdkn1b	4283	0.135	0.0209	No
56	Dck	4371	0.127	0.0165	No
57	Ak2	4422	0.123	0.0150	No
58	Mms22l	4428	0.122	0.0171	No
59	Srsf1	4469	0.119	0.0164	No
60	Lig1	4479	0.118	0.0181	No
61	Srsf2	4519	0.115	0.0173	No
62	Tubg1	4650	0.105	0.0089	No
63	Orc2	4651	0.105	0.0112	No
64	Cnot9	4703	0.101	0.0091	No
65	Mre11a	4830	0.092	0.0008	No
66	Prdx4	4851	0.090	0.0010	No
67	Wdr90	4983	0.080	-0.0080	No
68	Rad1	4990	0.079	-0.0068	No
69	Lbr	5071	0.073	-0.0118	No
70	Nme1	5166	0.067	-0.0181	No
71	Pms2	5173	0.066	-0.0172	No
72	Dnmt1	5253	0.061	-0.0223	No
73	Rad21	5269	0.059	-0.0223	No
74	Donson	5358	0.052	-0.0284	No
75	Dut	5622	0.035	-0.0492	No
76	Diaph3	5650	0.032	-0.0507	No
77	Brca1	5719	0.027	-0.0557	No
78	Atad2	5754	0.024	-0.0579	No
79	Tfrc	5774	0.023	-0.0590	No
80	Mcm4	5834	0.018	-0.0634	No
81	Dclre1b	5875	0.016	-0.0664	No
82	Ube2t	5899	0.014	-0.0679	No
83	Pole	5908	0.013	-0.0683	No
84	Spc24	5913	0.013	-0.0684	No
85	Cdc20	6019	0.007	-0.0768	No
86	Prkdc	6089	0.001	-0.0824	No
87	Zw10	6535	-0.012	-0.1185	No
88	Smc3	6615	-0.017	-0.1246	No
89	Chek2	6750	-0.025	-0.1350	No
90	Nup205	6784	-0.027	-0.1371	No
91	Usp1	6796	-0.027	-0.1374	No
92	Mcm3	6809	-0.028	-0.1378	No
93	Ube2s	6899	-0.033	-0.1444	No
94	Rfc2	7047	-0.043	-0.1555	No
95	Spag5	7129	-0.048	-0.1611	No
96	Paics	7135	-0.048	-0.1605	No
97	H2ax	7189	-0.052	-0.1637	No
98	Tipin	7243	-0.056	-0.1669	No
99	Psmc3ip	7261	-0.057	-0.1671	No
100	Mybl2	7355	-0.060	-0.1734	No
101	Pold2	7364	-0.060	-0.1728	No
102	Cks2	7387	-0.062	-0.1733	No
103	Xpo1	7466	-0.067	-0.1782	No
104	Nup107	7517	-0.070	-0.1809	No
105	Orc6	7568	-0.074	-0.1834	No
106	Pa2g4	7584	-0.075	-0.1830	No
107	Gins4	7635	-0.079	-0.1854	No
108	Dlgap5	7759	-0.087	-0.1937	No
109	Mad2l1	7837	-0.093	-0.1980	No
110	Pola2	7843	-0.094	-0.1964	No
111	Ssrp1	7951	-0.101	-0.2030	No
112	Pnn	8111	-0.111	-0.2136	No
113	Rpa1	8121	-0.112	-0.2120	No
114	Ppm1d	8163	-0.115	-0.2129	No
115	Bub1b	8238	-0.121	-0.2164	No
116	Jpt1	8253	-0.122	-0.2150	No
117	Nup153	8307	-0.126	-0.2167	No
118	Ran	8311	-0.126	-0.2143	No
119	Dek	8346	-0.129	-0.2143	No
120	Asf1a	8359	-0.130	-0.2126	No
121	Rrm2	8376	-0.131	-0.2111	No
122	Tra2b	8392	-0.132	-0.2096	No
123	Tacc3	8424	-0.135	-0.2092	No
124	Stmn1	8512	-0.141	-0.2134	No
125	Mki67	8533	-0.143	-0.2120	No
126	Timeless	8590	-0.147	-0.2135	No
127	Smc1a	8801	-0.162	-0.2272	No
128	Smc4	8854	-0.166	-0.2279	No
129	Chek1	8891	-0.169	-0.2273	No
130	Gspt1	8907	-0.170	-0.2250	No
131	Top2a	8923	-0.172	-0.2226	No
132	Cenpm	8971	-0.176	-0.2227	No
133	Cdk1	9037	-0.180	-0.2242	No
134	Rpa2	9047	-0.181	-0.2211	No
135	Wee1	9109	-0.187	-0.2222	No
136	Cdk4	9360	-0.206	-0.2382	No
137	Cdkn3	9515	-0.219	-0.2462	No
138	Stag1	9527	-0.220	-0.2425	No
139	Ctcf	9635	-0.229	-0.2464	Yes
140	Tmpo	9646	-0.230	-0.2424	Yes
141	Kif22	9654	-0.231	-0.2381	Yes
142	Trp53	9680	-0.233	-0.2352	Yes
143	Eed	9694	-0.235	-0.2313	Yes
144	Lsm8	9707	-0.236	-0.2273	Yes
145	Tubb5	9940	-0.254	-0.2409	Yes
146	Pds5b	10009	-0.260	-0.2410	Yes
147	Birc5	10047	-0.265	-0.2384	Yes
148	Melk	10049	-0.265	-0.2329	Yes
149	Cdca3	10162	-0.267	-0.2365	Yes
150	Cdca8	10243	-0.269	-0.2373	Yes
151	Rbbp7	10352	-0.281	-0.2402	Yes
152	Brms1l	10403	-0.288	-0.2382	Yes
153	E2f8	10406	-0.288	-0.2323	Yes
154	Mcm7	10434	-0.291	-0.2284	Yes
155	Trip13	10480	-0.296	-0.2258	Yes
156	Lmnb1	10512	-0.299	-0.2221	Yes
157	Gins3	10523	-0.300	-0.2166	Yes
158	Hmmr	10619	-0.312	-0.2178	Yes
159	Cdc25b	10755	-0.324	-0.2219	Yes
160	Spc25	10900	-0.339	-0.2266	Yes
161	Mlh1	10964	-0.349	-0.2243	Yes
162	Eif2s1	11015	-0.352	-0.2210	Yes
163	Rpa3	11102	-0.360	-0.2205	Yes
164	Tk1	11178	-0.371	-0.2188	Yes
165	Ccnb2	11343	-0.395	-0.2238	Yes
166	Rad50	11483	-0.418	-0.2264	Yes
167	Hells	11622	-0.449	-0.2282	Yes
168	Ubr7	11637	-0.450	-0.2198	Yes
169	Ncapd2	11641	-0.451	-0.2106	Yes
170	Kif18b	11657	-0.454	-0.2023	Yes
171	Dscc1	11667	-0.455	-0.1934	Yes
172	Kif2c	11672	-0.455	-0.1842	Yes
173	Rnaseh2a	11723	-0.463	-0.1785	Yes
174	Espl1	11798	-0.474	-0.1745	Yes
175	Cdkn2c	11806	-0.474	-0.1651	Yes
176	Nbn	11823	-0.476	-0.1564	Yes
177	Prim2	11827	-0.477	-0.1466	Yes
178	Suv39h1	11905	-0.502	-0.1423	Yes
179	Hmgb3	11952	-0.515	-0.1353	Yes
180	Rfc1	11960	-0.518	-0.1249	Yes
181	Luc7l3	11994	-0.531	-0.1164	Yes
182	Exosc8	12085	-0.564	-0.1119	Yes
183	Aurka	12095	-0.568	-0.1007	Yes
184	Cenpe	12102	-0.570	-0.0891	Yes
185	H2az1	12120	-0.579	-0.0783	Yes
186	Depdc1a	12163	-0.596	-0.0692	Yes
187	Brca2	12165	-0.597	-0.0567	Yes
188	Cit	12242	-0.649	-0.0493	Yes
189	Pttg1	12277	-0.671	-0.0379	Yes
190	Hmgb2	12347	-0.744	-0.0279	Yes
191	Kif4	12381	-0.793	-0.0139	Yes
192	Ing3	12413	-0.887	0.0023	Yes