Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Mast.Mast_Pheno.cls #Group3_versus_Group4.Mast_Pheno.cls #Group3_versus_Group4_repos |
| Phenotype | Mast_Pheno.cls#Group3_versus_Group4_repos |
| Upregulated in class | 3 |
| GeneSet | HALLMARK_IL6_JAK_STAT3_SIGNALING |
| Enrichment Score (ES) | -0.22364566 |
| Normalized Enrichment Score (NES) | -0.8720389 |
| Nominal p-value | 0.6693712 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Pik3r5 | 49 | 0.918 | 0.0611 | No |
| 2 | Stat1 | 510 | 0.564 | 0.0639 | No |
| 3 | Crlf2 | 640 | 0.522 | 0.0905 | No |
| 4 | Ccr1 | 1223 | 0.410 | 0.0726 | No |
| 5 | Grb2 | 1331 | 0.395 | 0.0919 | No |
| 6 | Pim1 | 1940 | 0.311 | 0.0649 | No |
| 7 | Acvr1b | 2000 | 0.302 | 0.0815 | No |
| 8 | Myd88 | 2040 | 0.298 | 0.0995 | No |
| 9 | Csf1 | 2055 | 0.297 | 0.1193 | No |
| 10 | Irf1 | 2114 | 0.291 | 0.1353 | No |
| 11 | Il7 | 2337 | 0.269 | 0.1364 | No |
| 12 | Tyk2 | 2391 | 0.266 | 0.1510 | No |
| 13 | Pf4 | 2807 | 0.227 | 0.1336 | No |
| 14 | Csf2ra | 2866 | 0.224 | 0.1448 | No |
| 15 | Tnf | 2977 | 0.214 | 0.1511 | No |
| 16 | Cd44 | 3092 | 0.208 | 0.1566 | No |
| 17 | Il6st | 3431 | 0.180 | 0.1420 | No |
| 18 | Stat2 | 3549 | 0.169 | 0.1445 | No |
| 19 | Cbl | 3762 | 0.151 | 0.1382 | No |
| 20 | Ifngr1 | 4037 | 0.131 | 0.1253 | No |
| 21 | Ltbr | 4535 | 0.096 | 0.0920 | No |
| 22 | Il10rb | 4871 | 0.071 | 0.0700 | No |
| 23 | Hax1 | 5137 | 0.054 | 0.0524 | No |
| 24 | Il2rg | 5566 | 0.027 | 0.0198 | No |
| 25 | Stat3 | 5850 | 0.010 | -0.0024 | No |
| 26 | Tgfb1 | 7224 | -0.069 | -0.1083 | No |
| 27 | Stam2 | 7359 | -0.077 | -0.1136 | No |
| 28 | Ptpn11 | 7455 | -0.083 | -0.1154 | No |
| 29 | Ifngr2 | 7491 | -0.086 | -0.1121 | No |
| 30 | Il17ra | 7620 | -0.094 | -0.1158 | No |
| 31 | Itga4 | 7699 | -0.100 | -0.1150 | No |
| 32 | Il18r1 | 7770 | -0.105 | -0.1132 | No |
| 33 | Ifnar1 | 7855 | -0.112 | -0.1120 | No |
| 34 | Bak1 | 7901 | -0.115 | -0.1075 | No |
| 35 | Il12rb1 | 7904 | -0.115 | -0.0995 | No |
| 36 | Irf9 | 8137 | -0.130 | -0.1091 | No |
| 37 | Il1r2 | 8322 | -0.143 | -0.1138 | No |
| 38 | Il17rb | 8554 | -0.158 | -0.1212 | No |
| 39 | Itgb3 | 8559 | -0.160 | -0.1102 | No |
| 40 | Ltb | 8738 | -0.173 | -0.1123 | No |
| 41 | Ptpn1 | 9114 | -0.200 | -0.1284 | No |
| 42 | Il9r | 9227 | -0.208 | -0.1227 | No |
| 43 | Il3ra | 9457 | -0.225 | -0.1252 | No |
| 44 | Tnfrsf1a | 9605 | -0.234 | -0.1205 | No |
| 45 | Il1r1 | 10116 | -0.276 | -0.1421 | No |
| 46 | Ptpn2 | 11127 | -0.387 | -0.1962 | Yes |
| 47 | Il6 | 11166 | -0.392 | -0.1715 | Yes |
| 48 | Jun | 11222 | -0.399 | -0.1477 | Yes |
| 49 | Tnfrsf21 | 11410 | -0.428 | -0.1324 | Yes |
| 50 | Cd9 | 11780 | -0.495 | -0.1271 | Yes |
| 51 | Il4ra | 11944 | -0.547 | -0.1015 | Yes |
| 52 | Tnfrsf1b | 11954 | -0.551 | -0.0632 | Yes |
| 53 | Il15ra | 12242 | -0.692 | -0.0374 | Yes |
| 54 | Csf3r | 12303 | -0.753 | 0.0111 | Yes |
