Details for gene set HALLMARK_E2F

Table: GSEA Results Summary

Dataset	Mast.Mast_Pheno.cls #Group3_versus_Group4.Mast_Pheno.cls #Group3_versus_Group4_repos
Phenotype	Mast_Pheno.cls#Group3_versus_Group4_repos
Upregulated in class	3
GeneSet	HALLMARK_E2F_TARGETS
Enrichment Score (ES)	-0.24946056
Normalized Enrichment Score (NES)	-0.92021066
Nominal p-value	0.55791503
FDR q-value	1.0
FWER p-Value	1.0

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Ppm1d	24	1.028	0.0202	No
2	Ak2	32	0.976	0.0406	No
3	Xpo1	60	0.890	0.0576	No
4	Dclre1b	171	0.740	0.0646	No
5	Espl1	419	0.606	0.0575	No
6	Nup153	550	0.550	0.0587	No
7	Chek2	610	0.534	0.0654	No
8	Rnaseh2a	667	0.515	0.0719	No
9	Wee1	779	0.490	0.0734	No
10	Tbrg4	791	0.487	0.0830	No
11	Pan2	987	0.453	0.0768	No
12	Dnmt1	1128	0.422	0.0745	No
13	Ssrp1	1346	0.394	0.0652	No
14	Dck	1348	0.394	0.0736	No
15	Stmn1	1353	0.393	0.0818	No
16	Cks2	1542	0.362	0.0742	No
17	Pms2	1610	0.352	0.0763	No
18	Timeless	1853	0.320	0.0635	No
19	Ncapd2	1856	0.320	0.0702	No
20	Nop56	1908	0.314	0.0728	No
21	Xrcc6	1919	0.313	0.0787	No
22	Brms1l	1948	0.309	0.0831	No
23	Exosc8	2110	0.292	0.0763	No
24	Rpa1	2148	0.286	0.0794	No
25	Mcm5	2329	0.270	0.0705	No
26	Orc6	2346	0.268	0.0750	No
27	Mcm6	2439	0.263	0.0731	No
28	Rrm2	2480	0.259	0.0755	No
29	Nup107	2557	0.251	0.0747	No
30	Ung	2706	0.235	0.0676	No
31	Tfrc	2738	0.233	0.0701	No
32	Srsf1	2788	0.229	0.0711	No
33	Gins3	2852	0.225	0.0708	No
34	Cdc25b	2916	0.219	0.0703	No
35	Pds5b	2944	0.216	0.0728	No
36	Tipin	3030	0.213	0.0704	No
37	Tubb5	3033	0.213	0.0749	No
38	Srsf2	3044	0.212	0.0786	No
39	Brca2	3085	0.209	0.0799	No
40	Phf5a	3220	0.197	0.0732	No
41	Asf1a	3343	0.187	0.0672	No
42	Ube2s	3400	0.183	0.0666	No
43	Hus1	3617	0.164	0.0525	No
44	Syncrip	3693	0.158	0.0498	No
45	Pole4	3895	0.142	0.0364	No
46	Ipo7	3931	0.139	0.0366	No
47	Rad50	4080	0.128	0.0273	No
48	Asf1b	4167	0.122	0.0229	No
49	Zw10	4205	0.119	0.0224	No
50	Cenpm	4277	0.113	0.0190	No
51	Rpa2	4299	0.112	0.0197	No
52	Kif18b	4446	0.103	0.0100	No
53	Aurka	4453	0.102	0.0117	No
54	Rad21	4476	0.100	0.0121	No
55	E2f8	4652	0.087	-0.0003	No
56	Chek1	4681	0.085	-0.0008	No
57	Paics	4715	0.082	-0.0017	No
58	Eed	4772	0.079	-0.0046	No
59	Suv39h1	4817	0.076	-0.0065	No
60	H2az1	4939	0.067	-0.0149	No
61	Ppp1r8	4968	0.066	-0.0158	No
62	Melk	4989	0.065	-0.0160	No
63	Mybl2	5045	0.060	-0.0192	No
64	Mthfd2	5082	0.058	-0.0209	No
65	Eif2s1	5187	0.050	-0.0283	No
66	Prim2	5191	0.050	-0.0275	No
67	Prps1	5392	0.037	-0.0430	No
68	Mre11a	5394	0.037	-0.0423	No
69	Mcm3	5412	0.036	-0.0429	No
70	Cdkn1b	5483	0.033	-0.0479	No
71	Atad2	5548	0.028	-0.0526	No
72	Trp53	5633	0.023	-0.0589	No
73	Nasp	5696	0.019	-0.0636	No
74	Brca1	5718	0.018	-0.0649	No
75	Ddx39a	5786	0.014	-0.0701	No
76	Dut	5888	0.007	-0.0782	No
77	Spc25	5902	0.006	-0.0791	No
78	Pold1	5914	0.005	-0.0799	No
79	Stag1	5916	0.005	-0.0799	No
80	Hmmr	5958	0.003	-0.0831	No
81	Lbr	6123	-0.003	-0.0965	No
82	Dek	6156	-0.004	-0.0990	No
83	Shmt1	6181	-0.005	-0.1009	No
84	Nbn	6182	-0.005	-0.1007	No
85	Dctpp1	6237	-0.009	-0.1050	No
86	Ccp110	6277	-0.011	-0.1079	No
87	Pola2	6295	-0.012	-0.1090	No
88	Luc7l3	6297	-0.012	-0.1089	No
89	Ctcf	6323	-0.014	-0.1106	No
90	Cdc20	6337	-0.016	-0.1113	No
91	Ilf3	6351	-0.017	-0.1120	No
92	Gspt1	6612	-0.032	-0.1326	No
93	Cnot9	6636	-0.034	-0.1337	No
94	Usp1	6741	-0.040	-0.1413	No
95	Trip13	6815	-0.045	-0.1463	No
96	Ube2t	6906	-0.051	-0.1526	No
97	Nudt21	7019	-0.057	-0.1605	No
98	Tacc3	7042	-0.059	-0.1610	No
99	Dscc1	7044	-0.059	-0.1598	No
100	Cdkn2c	7071	-0.061	-0.1606	No
101	Orc2	7376	-0.079	-0.1838	No
102	Cdk4	7384	-0.079	-0.1826	No
103	Kif22	7496	-0.086	-0.1898	No
104	Ing3	7574	-0.091	-0.1942	No
105	Cdc25a	7603	-0.093	-0.1945	No
106	Pnn	7641	-0.096	-0.1954	No
107	Birc5	7685	-0.099	-0.1968	No
108	Mlh1	7693	-0.100	-0.1952	No
109	Rbbp7	7700	-0.100	-0.1935	No
110	Gins4	7746	-0.104	-0.1950	No
111	Smc1a	7753	-0.105	-0.1932	No
112	Kif2c	7999	-0.121	-0.2106	No
113	Pole	8087	-0.127	-0.2150	No
114	Hnrnpd	8191	-0.133	-0.2205	No
115	Spag5	8228	-0.136	-0.2205	No
116	Nap1l1	8386	-0.146	-0.2302	No
117	Smc6	8550	-0.158	-0.2401	No
118	Pcna	8573	-0.161	-0.2384	No
119	Lig1	8581	-0.161	-0.2355	No
120	Prdx4	8623	-0.165	-0.2353	No
121	Spc24	8683	-0.170	-0.2365	No
122	Mms22l	8750	-0.174	-0.2381	No
123	Donson	8890	-0.184	-0.2455	Yes
124	Bub1b	8930	-0.187	-0.2447	Yes
125	Tmpo	8956	-0.189	-0.2426	Yes
126	Nolc1	8957	-0.189	-0.2386	Yes
127	Hells	8970	-0.189	-0.2355	Yes
128	Kif4	8985	-0.191	-0.2325	Yes
129	Ubr7	8992	-0.191	-0.2289	Yes
130	Nup205	9009	-0.192	-0.2260	Yes
131	Racgap1	9076	-0.198	-0.2271	Yes
132	Hmgb3	9078	-0.198	-0.2230	Yes
133	Aurkb	9084	-0.198	-0.2191	Yes
134	Nme1	9122	-0.201	-0.2178	Yes
135	Tra2b	9166	-0.203	-0.2169	Yes
136	Rpa3	9191	-0.205	-0.2145	Yes
137	H2ax	9354	-0.218	-0.2230	Yes
138	Tubg1	9360	-0.218	-0.2187	Yes
139	Ranbp1	9380	-0.220	-0.2155	Yes
140	Cdk1	9469	-0.226	-0.2178	Yes
141	Rfc1	9531	-0.227	-0.2179	Yes
142	Slbp	9628	-0.236	-0.2207	Yes
143	Rfc2	9644	-0.237	-0.2168	Yes
144	Cit	9667	-0.239	-0.2134	Yes
145	Pa2g4	9690	-0.240	-0.2100	Yes
146	Lsm8	9778	-0.247	-0.2118	Yes
147	Pold3	9861	-0.255	-0.2130	Yes
148	Snrpb	9914	-0.260	-0.2117	Yes
149	Smc3	9945	-0.263	-0.2084	Yes
150	Rad1	9985	-0.266	-0.2059	Yes
151	Msh2	9987	-0.266	-0.2003	Yes
152	Cdkn1a	10046	-0.270	-0.1992	Yes
153	Cenpe	10296	-0.294	-0.2132	Yes
154	Pold2	10348	-0.297	-0.2109	Yes
155	Cks1b	10353	-0.297	-0.2049	Yes
156	Ran	10459	-0.306	-0.2068	Yes
157	Mki67	10564	-0.318	-0.2085	Yes
158	Top2a	10616	-0.324	-0.2057	Yes
159	Mcm2	10677	-0.331	-0.2034	Yes
160	Psip1	10714	-0.335	-0.1991	Yes
161	Lyar	10734	-0.337	-0.1934	Yes
162	Cdca8	10772	-0.342	-0.1891	Yes
163	Hmgb2	10810	-0.347	-0.1846	Yes
164	Gins1	10862	-0.352	-0.1812	Yes
165	Jpt1	10880	-0.354	-0.1750	Yes
166	Depdc1a	10957	-0.363	-0.1734	Yes
167	Ezh2	10981	-0.366	-0.1674	Yes
168	Smc4	11110	-0.385	-0.1695	Yes
169	Cdca3	11123	-0.386	-0.1622	Yes
170	Mcm4	11168	-0.392	-0.1573	Yes
171	Rad51ap1	11182	-0.395	-0.1499	Yes
172	Mad2l1	11284	-0.410	-0.1493	Yes
173	Pttg1	11305	-0.412	-0.1421	Yes
174	Tk1	11356	-0.422	-0.1370	Yes
175	Cbx5	11373	-0.424	-0.1292	Yes
176	Cdkn3	11386	-0.425	-0.1210	Yes
177	Anp32e	11453	-0.432	-0.1171	Yes
178	Plk4	11461	-0.433	-0.1083	Yes
179	Dlgap5	11484	-0.437	-0.1007	Yes
180	Myc	11490	-0.438	-0.0917	Yes
181	Pop7	11652	-0.472	-0.0947	Yes
182	Prkdc	11878	-0.526	-0.1017	Yes
183	Lmnb1	11885	-0.528	-0.0908	Yes
184	Bard1	11886	-0.528	-0.0795	Yes
185	Mcm7	11971	-0.556	-0.0743	Yes
186	Ccnb2	12038	-0.579	-0.0673	Yes
187	Psmc3ip	12206	-0.668	-0.0665	Yes
188	Rfc3	12246	-0.694	-0.0547	Yes
189	Wdr90	12285	-0.729	-0.0421	Yes
190	Cse1l	12304	-0.753	-0.0274	Yes
191	Diaph3	12353	-0.819	-0.0137	Yes
192	Plk1	12402	-0.964	0.0032	Yes