Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Mast.Mast_Pheno.cls #Group2_versus_Group3.Mast_Pheno.cls #Group2_versus_Group3_repos |
| Phenotype | Mast_Pheno.cls#Group2_versus_Group3_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_IL6_JAK_STAT3_SIGNALING |
| Enrichment Score (ES) | 0.36510587 |
| Normalized Enrichment Score (NES) | 1.2137731 |
| Nominal p-value | 0.20898438 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.916 |
| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Il18r1 | 76 | 0.829 | 0.0442 | Yes |
| 2 | Stat3 | 205 | 0.704 | 0.0766 | Yes |
| 3 | Tnfrsf1b | 257 | 0.676 | 0.1135 | Yes |
| 4 | Ltb | 394 | 0.611 | 0.1396 | Yes |
| 5 | Il6 | 428 | 0.598 | 0.1732 | Yes |
| 6 | Jun | 441 | 0.595 | 0.2083 | Yes |
| 7 | Il2rg | 502 | 0.578 | 0.2386 | Yes |
| 8 | Csf3r | 602 | 0.541 | 0.2634 | Yes |
| 9 | Il1r2 | 742 | 0.508 | 0.2831 | Yes |
| 10 | Il17rb | 903 | 0.469 | 0.2986 | Yes |
| 11 | Itga4 | 909 | 0.469 | 0.3267 | Yes |
| 12 | Stat2 | 942 | 0.462 | 0.3521 | Yes |
| 13 | Il15ra | 1253 | 0.408 | 0.3518 | Yes |
| 14 | Il12rb1 | 1382 | 0.389 | 0.3651 | Yes |
| 15 | Cd44 | 2659 | 0.239 | 0.2766 | No |
| 16 | Il4ra | 2776 | 0.229 | 0.2812 | No |
| 17 | Tnf | 3018 | 0.205 | 0.2741 | No |
| 18 | Il1r1 | 3253 | 0.185 | 0.2665 | No |
| 19 | Ptpn11 | 3401 | 0.174 | 0.2652 | No |
| 20 | Il9r | 3595 | 0.159 | 0.2592 | No |
| 21 | Stam2 | 4131 | 0.117 | 0.2231 | No |
| 22 | Cd9 | 4511 | 0.086 | 0.1977 | No |
| 23 | Tnfrsf1a | 4559 | 0.082 | 0.1989 | No |
| 24 | Bak1 | 4924 | 0.060 | 0.1731 | No |
| 25 | Tnfrsf21 | 5058 | 0.050 | 0.1654 | No |
| 26 | Pf4 | 5375 | 0.029 | 0.1417 | No |
| 27 | Pik3r5 | 5916 | -0.006 | 0.0984 | No |
| 28 | Ifnar1 | 5968 | -0.010 | 0.0949 | No |
| 29 | Irf1 | 6343 | -0.035 | 0.0668 | No |
| 30 | Itgb3 | 6373 | -0.037 | 0.0668 | No |
| 31 | Hax1 | 6716 | -0.062 | 0.0429 | No |
| 32 | Ltbr | 6770 | -0.066 | 0.0426 | No |
| 33 | Il3ra | 6794 | -0.068 | 0.0449 | No |
| 34 | Acvr1b | 7120 | -0.091 | 0.0242 | No |
| 35 | Pim1 | 7415 | -0.111 | 0.0072 | No |
| 36 | Ptpn1 | 7516 | -0.118 | 0.0063 | No |
| 37 | Irf9 | 7733 | -0.132 | -0.0031 | No |
| 38 | Stat1 | 8116 | -0.160 | -0.0242 | No |
| 39 | Grb2 | 8595 | -0.192 | -0.0511 | No |
| 40 | Il6st | 9033 | -0.227 | -0.0726 | No |
| 41 | Ifngr2 | 9105 | -0.233 | -0.0642 | No |
| 42 | Ptpn2 | 9215 | -0.241 | -0.0584 | No |
| 43 | Myd88 | 9804 | -0.289 | -0.0883 | No |
| 44 | Csf1 | 10261 | -0.336 | -0.1048 | No |
| 45 | Ifngr1 | 10323 | -0.342 | -0.0889 | No |
| 46 | Crlf2 | 10393 | -0.349 | -0.0733 | No |
| 47 | Il7 | 10737 | -0.387 | -0.0775 | No |
| 48 | Tgfb1 | 10813 | -0.397 | -0.0594 | No |
| 49 | Csf2ra | 11163 | -0.441 | -0.0609 | No |
| 50 | Il10rb | 11168 | -0.441 | -0.0345 | No |
| 51 | Il17ra | 11245 | -0.453 | -0.0131 | No |
| 52 | Tyk2 | 11746 | -0.549 | -0.0201 | No |
| 53 | Cbl | 11902 | -0.593 | 0.0033 | No |
| 54 | Ccr1 | 12078 | -0.661 | 0.0293 | No |
