| Dataset | Mast.Mast_Pheno.cls #Group2_versus_Group3.Mast_Pheno.cls #Group2_versus_Group3_repos |
| Phenotype | Mast_Pheno.cls#Group2_versus_Group3_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_G2M_CHECKPOINT |
| Enrichment Score (ES) | 0.24289404 |
| Normalized Enrichment Score (NES) | 1.0429075 |
| Nominal p-value | 0.3859649 |
| FDR q-value | 0.9492029 |
| FWER p-Value | 0.997 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Cdk1 | 18 | 1.017 | 0.0200 | Yes |
| 2 | Ndc80 | 80 | 0.823 | 0.0323 | Yes |
| 3 | Kif23 | 85 | 0.811 | 0.0491 | Yes |
| 4 | Rasal2 | 118 | 0.770 | 0.0627 | Yes |
| 5 | Dmd | 167 | 0.727 | 0.0741 | Yes |
| 6 | Hspa8 | 213 | 0.698 | 0.0852 | Yes |
| 7 | Plk1 | 337 | 0.637 | 0.0886 | Yes |
| 8 | Incenp | 532 | 0.563 | 0.0846 | Yes |
| 9 | Ccnt1 | 575 | 0.549 | 0.0927 | Yes |
| 10 | Nsd2 | 622 | 0.535 | 0.1003 | Yes |
| 11 | Odf2 | 771 | 0.501 | 0.0988 | Yes |
| 12 | Tle3 | 798 | 0.494 | 0.1070 | Yes |
| 13 | Ezh2 | 858 | 0.478 | 0.1123 | Yes |
| 14 | Tmpo | 885 | 0.473 | 0.1201 | Yes |
| 15 | Lbr | 963 | 0.457 | 0.1235 | Yes |
| 16 | Meis1 | 1029 | 0.445 | 0.1276 | Yes |
| 17 | Orc5 | 1034 | 0.444 | 0.1366 | Yes |
| 18 | Pbk | 1082 | 0.435 | 0.1420 | Yes |
| 19 | Sqle | 1189 | 0.420 | 0.1422 | Yes |
| 20 | Pura | 1278 | 0.404 | 0.1435 | Yes |
| 21 | Cdc7 | 1309 | 0.400 | 0.1495 | Yes |
| 22 | Srsf1 | 1379 | 0.390 | 0.1521 | Yes |
| 23 | H2az1 | 1569 | 0.361 | 0.1442 | Yes |
| 24 | Amd1 | 1669 | 0.347 | 0.1435 | Yes |
| 25 | Casp8ap2 | 1679 | 0.345 | 0.1500 | Yes |
| 26 | Hnrnpu | 1684 | 0.344 | 0.1569 | Yes |
| 27 | Numa1 | 1711 | 0.340 | 0.1620 | Yes |
| 28 | Top1 | 1715 | 0.340 | 0.1689 | Yes |
| 29 | Kif15 | 1848 | 0.323 | 0.1649 | Yes |
| 30 | Exo1 | 1877 | 0.319 | 0.1694 | Yes |
| 31 | Upf1 | 1898 | 0.317 | 0.1744 | Yes |
| 32 | Cul5 | 1899 | 0.317 | 0.1811 | Yes |
| 33 | Prc1 | 1999 | 0.305 | 0.1795 | Yes |
| 34 | Egf | 2087 | 0.295 | 0.1786 | Yes |
| 35 | Smc4 | 2088 | 0.295 | 0.1848 | Yes |
| 36 | Tfdp1 | 2103 | 0.294 | 0.1899 | Yes |
| 37 | Slc7a1 | 2187 | 0.284 | 0.1891 | Yes |
| 38 | Cul1 | 2215 | 0.282 | 0.1928 | Yes |
| 39 | Xpo1 | 2232 | 0.279 | 0.1974 | Yes |
| 40 | Tra2b | 2308 | 0.274 | 0.1970 | Yes |
| 41 | Pttg1 | 2309 | 0.274 | 0.2028 | Yes |
| 42 | Ddx39a | 2332 | 0.272 | 0.2068 | Yes |
| 43 | Cdkn2c | 2336 | 0.271 | 0.2122 | Yes |
| 44 | Gins2 | 2414 | 0.265 | 0.2115 | Yes |
| 45 | Smarcc1 | 2470 | 0.260 | 0.2125 | Yes |
| 46 | Knl1 | 2529 | 0.254 | 0.2131 | Yes |
| 47 | Jpt1 | 2539 | 0.253 | 0.2177 | Yes |
| 48 | Ttk | 2657 | 0.240 | 0.2132 | Yes |
| 49 | Cdkn3 | 2676 | 0.238 | 0.2168 | Yes |
| 50 | Slc12a2 | 2751 | 0.232 | 0.2156 | Yes |
| 51 | Racgap1 | 2759 | 0.230 | 0.2199 | Yes |
| 52 | Bub3 | 2828 | 0.223 | 0.2191 | Yes |
| 53 | Plk4 | 2858 | 0.220 | 0.2213 | Yes |
| 54 | Prim2 | 2880 | 0.218 | 0.2242 | Yes |
| 55 | Tpx2 | 2888 | 0.217 | 0.2282 | Yes |
| 56 | Ccnf | 2919 | 0.214 | 0.2303 | Yes |
| 57 | Arid4a | 2928 | 0.213 | 0.2341 | Yes |
| 58 | Bcl3 | 2961 | 0.210 | 0.2359 | Yes |
| 59 | Cenpe | 2986 | 0.208 | 0.2384 | Yes |
| 60 | Kpnb1 | 3027 | 0.205 | 0.2394 | Yes |
| 61 | Cdc27 | 3038 | 0.204 | 0.2429 | Yes |
| 62 | Smad3 | 3380 | 0.176 | 0.2188 | No |
| 63 | Pafah1b1 | 3566 | 0.160 | 0.2070 | No |
| 64 | Cdc25a | 3780 | 0.144 | 0.1927 | No |
| 65 | Slc7a5 | 3799 | 0.143 | 0.1942 | No |
| 66 | Prpf4b | 3847 | 0.139 | 0.1933 | No |
| 67 | Pds5b | 3924 | 0.132 | 0.1899 | No |
| 68 | Troap | 3938 | 0.131 | 0.1916 | No |
| 69 | Mcm3 | 4026 | 0.125 | 0.1872 | No |
| 70 | Kif4 | 4129 | 0.117 | 0.1813 | No |
| 71 | Fbxo5 | 4216 | 0.111 | 0.1766 | No |
| 72 | Mad2l1 | 4250 | 0.108 | 0.1762 | No |
| 73 | Rps6ka5 | 4304 | 0.104 | 0.1741 | No |
| 74 | Ube2s | 4306 | 0.104 | 0.1762 | No |
| 75 | Sfpq | 4388 | 0.096 | 0.1716 | No |
| 76 | Sap30 | 4415 | 0.094 | 0.1715 | No |
| 77 | Hif1a | 4445 | 0.092 | 0.1710 | No |
| 78 | Traip | 4451 | 0.091 | 0.1725 | No |
| 79 | Cenpf | 4568 | 0.081 | 0.1648 | No |
| 80 | Syncrip | 4676 | 0.074 | 0.1576 | No |
| 81 | Hmmr | 4731 | 0.071 | 0.1547 | No |
| 82 | Ythdc1 | 4794 | 0.068 | 0.1511 | No |
| 83 | Hnrnpd | 4878 | 0.062 | 0.1456 | No |
| 84 | Smc2 | 4885 | 0.062 | 0.1464 | No |
| 85 | Cdkn1b | 4977 | 0.056 | 0.1402 | No |
| 86 | Nasp | 5078 | 0.049 | 0.1331 | No |
| 87 | Smc1a | 5097 | 0.047 | 0.1326 | No |
| 88 | Dtymk | 5110 | 0.047 | 0.1326 | No |
| 89 | Mki67 | 5121 | 0.046 | 0.1327 | No |
| 90 | Ctcf | 5122 | 0.046 | 0.1337 | No |
| 91 | Kif20b | 5128 | 0.045 | 0.1342 | No |
| 92 | Myc | 5145 | 0.044 | 0.1339 | No |
| 93 | Mnat1 | 5160 | 0.043 | 0.1336 | No |
| 94 | Rpa2 | 5282 | 0.035 | 0.1245 | No |
| 95 | Uck2 | 5309 | 0.033 | 0.1231 | No |
| 96 | Ilf3 | 5324 | 0.032 | 0.1226 | No |
| 97 | Nup98 | 5502 | 0.021 | 0.1086 | No |
| 98 | Dr1 | 5509 | 0.020 | 0.1085 | No |
| 99 | Notch2 | 5535 | 0.018 | 0.1069 | No |
| 100 | Hus1 | 5728 | 0.006 | 0.0913 | No |
| 101 | Kif5b | 5805 | 0.001 | 0.0851 | No |
| 102 | Cks1b | 5821 | 0.000 | 0.0839 | No |
| 103 | Lmnb1 | 5971 | -0.010 | 0.0720 | No |
| 104 | E2f1 | 6047 | -0.015 | 0.0662 | No |
| 105 | Atf5 | 6276 | -0.031 | 0.0482 | No |
| 106 | Dkc1 | 6374 | -0.037 | 0.0411 | No |
| 107 | Ube2c | 6447 | -0.043 | 0.0361 | No |
| 108 | Cenpa | 6456 | -0.044 | 0.0364 | No |
| 109 | Prmt5 | 6599 | -0.053 | 0.0259 | No |
| 110 | Kif2c | 6666 | -0.058 | 0.0218 | No |
| 111 | Ccnb2 | 6699 | -0.061 | 0.0204 | No |
| 112 | Pole | 6704 | -0.061 | 0.0214 | No |
| 113 | Cdk4 | 6720 | -0.062 | 0.0215 | No |
| 114 | Bard1 | 6723 | -0.063 | 0.0227 | No |
| 115 | Rad21 | 6836 | -0.071 | 0.0150 | No |
| 116 | Brca2 | 6863 | -0.073 | 0.0144 | No |
| 117 | Stag1 | 6878 | -0.074 | 0.0149 | No |
| 118 | Mcm2 | 7076 | -0.089 | 0.0007 | No |
| 119 | Birc5 | 7330 | -0.105 | -0.0178 | No |
| 120 | Rbl1 | 7413 | -0.111 | -0.0221 | No |
| 121 | H2ax | 7419 | -0.111 | -0.0202 | No |
| 122 | Nup50 | 7450 | -0.113 | -0.0203 | No |
| 123 | Mybl2 | 7476 | -0.115 | -0.0199 | No |
| 124 | G3bp1 | 7569 | -0.121 | -0.0248 | No |
| 125 | Ss18 | 7613 | -0.124 | -0.0257 | No |
| 126 | Mcm5 | 7621 | -0.124 | -0.0237 | No |
| 127 | Nek2 | 7631 | -0.125 | -0.0218 | No |
| 128 | Nusap1 | 7689 | -0.129 | -0.0237 | No |
| 129 | Polq | 7702 | -0.130 | -0.0219 | No |
| 130 | Chek1 | 7741 | -0.133 | -0.0222 | No |
| 131 | Abl1 | 7759 | -0.134 | -0.0208 | No |
| 132 | Pola2 | 7823 | -0.139 | -0.0230 | No |
| 133 | Rad23b | 8009 | -0.153 | -0.0349 | No |
| 134 | Lig3 | 8020 | -0.154 | -0.0324 | No |
| 135 | Top2a | 8076 | -0.158 | -0.0336 | No |
| 136 | Srsf2 | 8295 | -0.172 | -0.0478 | No |
| 137 | Kmt5a | 8348 | -0.176 | -0.0483 | No |
| 138 | Snrpd1 | 8391 | -0.179 | -0.0480 | No |
| 139 | Bub1 | 8434 | -0.181 | -0.0476 | No |
| 140 | Kif11 | 8448 | -0.183 | -0.0448 | No |
| 141 | Mapk14 | 8487 | -0.185 | -0.0440 | No |
| 142 | Stil | 8499 | -0.185 | -0.0410 | No |
| 143 | Nolc1 | 8776 | -0.207 | -0.0591 | No |
| 144 | Mtf2 | 8794 | -0.209 | -0.0561 | No |
| 145 | Ncl | 8796 | -0.209 | -0.0518 | No |
| 146 | Fancc | 8800 | -0.209 | -0.0476 | No |
| 147 | Stmn1 | 8929 | -0.219 | -0.0535 | No |
| 148 | Gspt1 | 8968 | -0.223 | -0.0519 | No |
| 149 | E2f3 | 9163 | -0.237 | -0.0627 | No |
| 150 | Cdc25b | 9174 | -0.239 | -0.0585 | No |
| 151 | Chaf1a | 9361 | -0.254 | -0.0683 | No |
| 152 | Hmgb3 | 9496 | -0.264 | -0.0737 | No |
| 153 | Aurkb | 9562 | -0.269 | -0.0733 | No |
| 154 | Chmp1a | 9698 | -0.280 | -0.0784 | No |
| 155 | Hira | 9724 | -0.283 | -0.0745 | No |
| 156 | Orc6 | 9728 | -0.283 | -0.0688 | No |
| 157 | Dbf4 | 9732 | -0.283 | -0.0631 | No |
| 158 | Cdc6 | 9739 | -0.284 | -0.0576 | No |
| 159 | Aurka | 9782 | -0.288 | -0.0550 | No |
| 160 | Tnpo2 | 9867 | -0.295 | -0.0556 | No |
| 161 | Tacc3 | 9957 | -0.305 | -0.0564 | No |
| 162 | Srsf10 | 10090 | -0.318 | -0.0605 | No |
| 163 | Ewsr1 | 10115 | -0.320 | -0.0557 | No |
| 164 | Mcm6 | 10181 | -0.327 | -0.0541 | No |
| 165 | Atrx | 10256 | -0.335 | -0.0531 | No |
| 166 | Cul3 | 10258 | -0.335 | -0.0461 | No |
| 167 | Cdc45 | 10282 | -0.337 | -0.0409 | No |
| 168 | Odc1 | 10358 | -0.346 | -0.0397 | No |
| 169 | Slc38a1 | 10376 | -0.347 | -0.0338 | No |
| 170 | Ccna2 | 10525 | -0.363 | -0.0382 | No |
| 171 | Pml | 10609 | -0.373 | -0.0371 | No |
| 172 | Espl1 | 10640 | -0.377 | -0.0316 | No |
| 173 | E2f2 | 10715 | -0.385 | -0.0295 | No |
| 174 | Cdc20 | 10779 | -0.392 | -0.0264 | No |
| 175 | Tgfb1 | 10813 | -0.397 | -0.0208 | No |
| 176 | Wrn | 10840 | -0.400 | -0.0144 | No |
| 177 | Marcks | 10859 | -0.403 | -0.0074 | No |
| 178 | Suv39h1 | 11100 | -0.433 | -0.0179 | No |
| 179 | Rad54l | 11165 | -0.441 | -0.0138 | No |
| 180 | Cul4a | 11218 | -0.450 | -0.0086 | No |
| 181 | Tent4a | 11324 | -0.466 | -0.0073 | No |
| 182 | Map3k20 | 11529 | -0.499 | -0.0135 | No |
| 183 | H2az2 | 11605 | -0.514 | -0.0088 | No |
| 184 | Kif22 | 11607 | -0.515 | 0.0020 | No |
| 185 | Katna1 | 11704 | -0.538 | 0.0055 | No |
| 186 | Cbx1 | 11843 | -0.574 | 0.0064 | No |
| 187 | Foxn3 | 11951 | -0.607 | 0.0104 | No |
| 188 | Cks2 | 11961 | -0.611 | 0.0226 | No |
| 189 | E2f4 | 12267 | -0.784 | 0.0142 | No |

