| Dataset | Mast.Mast_Pheno.cls #Group1_versus_Group4.Mast_Pheno.cls #Group1_versus_Group4_repos |
| Phenotype | Mast_Pheno.cls#Group1_versus_Group4_repos |
| Upregulated in class | 3 |
| GeneSet | HALLMARK_MYC_TARGETS_V1 |
| Enrichment Score (ES) | -0.3539707 |
| Normalized Enrichment Score (NES) | -1.465839 |
| Nominal p-value | 0.058380414 |
| FDR q-value | 0.112231 |
| FWER p-Value | 0.363 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Xpo1 | 24 | 0.973 | 0.0158 | No |
| 2 | Mcm5 | 140 | 0.752 | 0.0202 | No |
| 3 | Hspd1 | 154 | 0.742 | 0.0327 | No |
| 4 | Kpnb1 | 163 | 0.737 | 0.0455 | No |
| 5 | Rrp9 | 454 | 0.581 | 0.0324 | No |
| 6 | Hnrnpa1 | 534 | 0.555 | 0.0361 | No |
| 7 | Hnrnpa3 | 685 | 0.511 | 0.0332 | No |
| 8 | Hnrnpa2b1 | 767 | 0.489 | 0.0356 | No |
| 9 | Psmd3 | 806 | 0.477 | 0.0412 | No |
| 10 | Fam120a | 1002 | 0.442 | 0.0333 | No |
| 11 | Smarcc1 | 1103 | 0.422 | 0.0329 | No |
| 12 | Eif4g2 | 1125 | 0.416 | 0.0388 | No |
| 13 | Ndufab1 | 1137 | 0.413 | 0.0454 | No |
| 14 | Cul1 | 1202 | 0.399 | 0.0475 | No |
| 15 | Tomm70a | 1210 | 0.399 | 0.0542 | No |
| 16 | H2az1 | 1413 | 0.369 | 0.0445 | No |
| 17 | Hnrnpu | 1716 | 0.330 | 0.0259 | No |
| 18 | Nop16 | 1750 | 0.326 | 0.0291 | No |
| 19 | Ncbp1 | 1817 | 0.319 | 0.0296 | No |
| 20 | Srsf1 | 1853 | 0.315 | 0.0325 | No |
| 21 | Rrm1 | 1913 | 0.308 | 0.0333 | No |
| 22 | Mrps18b | 2145 | 0.283 | 0.0196 | No |
| 23 | Cdc45 | 2195 | 0.278 | 0.0207 | No |
| 24 | Psmd7 | 2275 | 0.271 | 0.0192 | No |
| 25 | C1qbp | 2285 | 0.271 | 0.0234 | No |
| 26 | Vdac3 | 2286 | 0.270 | 0.0283 | No |
| 27 | Canx | 2318 | 0.268 | 0.0307 | No |
| 28 | Ilf2 | 2333 | 0.266 | 0.0344 | No |
| 29 | Ywhae | 2620 | 0.238 | 0.0154 | No |
| 30 | Ruvbl2 | 2856 | 0.215 | 0.0002 | No |
| 31 | Aimp2 | 2931 | 0.207 | -0.0021 | No |
| 32 | Srpk1 | 3012 | 0.200 | -0.0049 | No |
| 33 | Eif4e | 3139 | 0.189 | -0.0118 | No |
| 34 | Uba2 | 3178 | 0.185 | -0.0115 | No |
| 35 | Hnrnpr | 3184 | 0.185 | -0.0085 | No |
| 36 | Xpot | 3190 | 0.185 | -0.0055 | No |
| 37 | Syncrip | 3215 | 0.183 | -0.0042 | No |
| 38 | Pcna | 3281 | 0.179 | -0.0062 | No |
| 39 | Sf3b3 | 3472 | 0.164 | -0.0187 | No |
| 40 | Mcm6 | 3710 | 0.145 | -0.0354 | No |
| 41 | Eif2s1 | 3797 | 0.138 | -0.0399 | No |
| 42 | Exosc7 | 3910 | 0.128 | -0.0467 | No |
| 43 | Pwp1 | 3961 | 0.124 | -0.0485 | No |
| 44 | Srsf3 | 3973 | 0.123 | -0.0471 | No |
| 45 | Ppia | 3989 | 0.122 | -0.0461 | No |
| 46 | Ddx21 | 4142 | 0.114 | -0.0565 | No |
| 47 | Psmc4 | 4150 | 0.113 | -0.0550 | No |
| 48 | Cbx3 | 4392 | 0.094 | -0.0729 | No |
| 49 | Psmc6 | 4498 | 0.086 | -0.0799 | No |
| 50 | Psmb2 | 4627 | 0.077 | -0.0889 | No |
| 51 | G3bp1 | 4649 | 0.075 | -0.0893 | No |
| 52 | Psmd1 | 4742 | 0.067 | -0.0955 | No |
| 53 | Usp1 | 4789 | 0.065 | -0.0981 | No |
| 54 | Odc1 | 4864 | 0.059 | -0.1031 | No |
| 55 | Xrcc6 | 5039 | 0.049 | -0.1164 | No |
| 56 | Rfc4 | 5072 | 0.047 | -0.1181 | No |
| 57 | Mcm2 | 5205 | 0.037 | -0.1282 | No |
| 58 | Cnbp | 5237 | 0.035 | -0.1301 | No |
| 59 | Cdk2 | 5254 | 0.034 | -0.1308 | No |
| 60 | Cops5 | 5551 | 0.013 | -0.1547 | No |
| 61 | Hnrnpd | 5561 | 0.013 | -0.1552 | No |
| 62 | Pole3 | 5616 | 0.009 | -0.1594 | No |
| 63 | Ifrd1 | 5678 | 0.004 | -0.1643 | No |
| 64 | Eif4a1 | 5716 | 0.002 | -0.1673 | No |
| 65 | Snrpd1 | 5738 | 0.001 | -0.1690 | No |
| 66 | Ywhaq | 5898 | -0.008 | -0.1819 | No |
| 67 | Nolc1 | 5943 | -0.011 | -0.1852 | No |
| 68 | Snrpa1 | 6079 | -0.019 | -0.1959 | No |
| 69 | Tufm | 6116 | -0.021 | -0.1985 | No |
| 70 | Pabpc4 | 6154 | -0.024 | -0.2010 | No |
| 71 | Glo1 | 6166 | -0.024 | -0.2015 | No |
| 72 | Phb2 | 6321 | -0.035 | -0.2134 | No |
| 73 | Slc25a3 | 6353 | -0.037 | -0.2153 | No |
| 74 | Etf1 | 6459 | -0.044 | -0.2230 | No |
| 75 | Psma6 | 6523 | -0.048 | -0.2273 | No |
| 76 | Prpf31 | 6560 | -0.051 | -0.2293 | No |
| 77 | Pa2g4 | 6601 | -0.052 | -0.2316 | No |
| 78 | Ran | 6620 | -0.054 | -0.2321 | No |
| 79 | Got2 | 6824 | -0.066 | -0.2475 | No |
| 80 | Rps6 | 6927 | -0.072 | -0.2545 | No |
| 81 | Prps2 | 7099 | -0.083 | -0.2669 | No |
| 82 | Mcm4 | 7236 | -0.093 | -0.2763 | No |
| 83 | Gspt1 | 7308 | -0.097 | -0.2803 | No |
| 84 | Mrpl9 | 7318 | -0.098 | -0.2793 | No |
| 85 | Nhp2 | 7328 | -0.099 | -0.2782 | No |
| 86 | Ube2e1 | 7394 | -0.104 | -0.2816 | No |
| 87 | Ap3s1 | 7400 | -0.104 | -0.2801 | No |
| 88 | Vdac1 | 7422 | -0.105 | -0.2799 | No |
| 89 | Orc2 | 7491 | -0.110 | -0.2834 | No |
| 90 | Nop56 | 7579 | -0.116 | -0.2884 | No |
| 91 | Gnl3 | 7617 | -0.119 | -0.2893 | No |
| 92 | Srsf7 | 7630 | -0.120 | -0.2881 | No |
| 93 | Mrpl23 | 7753 | -0.128 | -0.2957 | No |
| 94 | Rnps1 | 7763 | -0.129 | -0.2941 | No |
| 95 | Mcm7 | 7780 | -0.130 | -0.2930 | No |
| 96 | Pold2 | 7848 | -0.134 | -0.2960 | No |
| 97 | Snrpb2 | 7849 | -0.134 | -0.2936 | No |
| 98 | Tra2b | 7868 | -0.136 | -0.2925 | No |
| 99 | Eif2s2 | 7919 | -0.139 | -0.2941 | No |
| 100 | Ddx18 | 7955 | -0.141 | -0.2944 | No |
| 101 | Rpl14 | 7972 | -0.143 | -0.2931 | No |
| 102 | Hddc2 | 7995 | -0.144 | -0.2922 | No |
| 103 | Npm1 | 8200 | -0.158 | -0.3060 | No |
| 104 | Eif3b | 8286 | -0.164 | -0.3099 | No |
| 105 | Prdx4 | 8301 | -0.165 | -0.3080 | No |
| 106 | Pabpc1 | 8529 | -0.181 | -0.3232 | No |
| 107 | Pcbp1 | 8544 | -0.182 | -0.3211 | No |
| 108 | Rpl22 | 8609 | -0.187 | -0.3229 | No |
| 109 | Tfdp1 | 8659 | -0.191 | -0.3234 | No |
| 110 | Fbl | 8730 | -0.196 | -0.3255 | No |
| 111 | Rsl1d1 | 8736 | -0.196 | -0.3223 | No |
| 112 | Cct2 | 8974 | -0.215 | -0.3377 | No |
| 113 | Snrpd3 | 8996 | -0.216 | -0.3355 | No |
| 114 | Serbp1 | 9081 | -0.222 | -0.3383 | No |
| 115 | Abce1 | 9162 | -0.228 | -0.3407 | No |
| 116 | Rpl18 | 9326 | -0.241 | -0.3496 | Yes |
| 117 | Ssbp1 | 9348 | -0.242 | -0.3469 | Yes |
| 118 | Nap1l1 | 9353 | -0.243 | -0.3427 | Yes |
| 119 | Nme1 | 9391 | -0.247 | -0.3413 | Yes |
| 120 | Cct4 | 9436 | -0.251 | -0.3403 | Yes |
| 121 | Psmd14 | 9459 | -0.253 | -0.3374 | Yes |
| 122 | Cstf2 | 9523 | -0.259 | -0.3378 | Yes |
| 123 | Dhx15 | 9578 | -0.263 | -0.3374 | Yes |
| 124 | Stard7 | 9778 | -0.280 | -0.3486 | Yes |
| 125 | Hspe1 | 9785 | -0.281 | -0.3439 | Yes |
| 126 | Cad | 9795 | -0.282 | -0.3395 | Yes |
| 127 | Snrpd2 | 9838 | -0.286 | -0.3377 | Yes |
| 128 | Rps10 | 9883 | -0.290 | -0.3360 | Yes |
| 129 | Mad2l1 | 9900 | -0.291 | -0.3320 | Yes |
| 130 | Trim28 | 9903 | -0.292 | -0.3268 | Yes |
| 131 | Erh | 10016 | -0.301 | -0.3305 | Yes |
| 132 | Prdx3 | 10059 | -0.306 | -0.3283 | Yes |
| 133 | Bub3 | 10079 | -0.306 | -0.3242 | Yes |
| 134 | Cdc20 | 10104 | -0.308 | -0.3206 | Yes |
| 135 | Cox5a | 10128 | -0.310 | -0.3168 | Yes |
| 136 | Ppm1g | 10151 | -0.312 | -0.3129 | Yes |
| 137 | Lsm2 | 10181 | -0.315 | -0.3095 | Yes |
| 138 | Cct5 | 10246 | -0.321 | -0.3089 | Yes |
| 139 | Cyc1 | 10259 | -0.322 | -0.3040 | Yes |
| 140 | Psma4 | 10274 | -0.323 | -0.2992 | Yes |
| 141 | Psma1 | 10285 | -0.325 | -0.2941 | Yes |
| 142 | Vbp1 | 10312 | -0.327 | -0.2902 | Yes |
| 143 | Psmd8 | 10483 | -0.345 | -0.2978 | Yes |
| 144 | Txnl4a | 10544 | -0.353 | -0.2962 | Yes |
| 145 | Tardbp | 10559 | -0.354 | -0.2909 | Yes |
| 146 | Pgk1 | 10562 | -0.355 | -0.2846 | Yes |
| 147 | Clns1a | 10599 | -0.361 | -0.2809 | Yes |
| 148 | Snrpa | 10631 | -0.365 | -0.2768 | Yes |
| 149 | Hdac2 | 10705 | -0.372 | -0.2759 | Yes |
| 150 | Cdk4 | 10797 | -0.384 | -0.2764 | Yes |
| 151 | Psma7 | 10912 | -0.398 | -0.2784 | Yes |
| 152 | Rad23b | 10952 | -0.403 | -0.2742 | Yes |
| 153 | Ccna2 | 10960 | -0.404 | -0.2674 | Yes |
| 154 | Eef1b2 | 10994 | -0.408 | -0.2626 | Yes |
| 155 | Hnrnpc | 11054 | -0.417 | -0.2598 | Yes |
| 156 | Rack1 | 11081 | -0.420 | -0.2543 | Yes |
| 157 | Dut | 11165 | -0.431 | -0.2532 | Yes |
| 158 | Eif3j1 | 11223 | -0.442 | -0.2498 | Yes |
| 159 | Eif4h | 11247 | -0.447 | -0.2435 | Yes |
| 160 | Ssb | 11513 | -0.494 | -0.2561 | Yes |
| 161 | Hdgf | 11534 | -0.500 | -0.2486 | Yes |
| 162 | Snrpg | 11599 | -0.513 | -0.2444 | Yes |
| 163 | Sf3a1 | 11653 | -0.522 | -0.2392 | Yes |
| 164 | Rplp0 | 11726 | -0.538 | -0.2352 | Yes |
| 165 | Rpl6 | 11780 | -0.554 | -0.2294 | Yes |
| 166 | Acp1 | 11833 | -0.571 | -0.2233 | Yes |
| 167 | Dek | 11875 | -0.584 | -0.2159 | Yes |
| 168 | Tcp1 | 11929 | -0.603 | -0.2092 | Yes |
| 169 | Ldha | 11956 | -0.611 | -0.2002 | Yes |
| 170 | Cct7 | 11987 | -0.623 | -0.1913 | Yes |
| 171 | Psma2 | 12001 | -0.626 | -0.1809 | Yes |
| 172 | Psmb3 | 12004 | -0.627 | -0.1696 | Yes |
| 173 | Tyms | 12018 | -0.630 | -0.1591 | Yes |
| 174 | Hsp90ab1 | 12145 | -0.694 | -0.1568 | Yes |
| 175 | Srm | 12167 | -0.703 | -0.1456 | Yes |
| 176 | Srsf2 | 12180 | -0.711 | -0.1336 | Yes |
| 177 | Myc | 12227 | -0.743 | -0.1238 | Yes |
| 178 | Impdh2 | 12233 | -0.746 | -0.1106 | Yes |
| 179 | Cct3 | 12242 | -0.756 | -0.0974 | Yes |
| 180 | Apex1 | 12260 | -0.776 | -0.0846 | Yes |
| 181 | Rps2 | 12300 | -0.816 | -0.0729 | Yes |
| 182 | Ranbp1 | 12302 | -0.818 | -0.0580 | Yes |
| 183 | Ncbp2 | 12311 | -0.825 | -0.0436 | Yes |
| 184 | Eif3d | 12388 | -0.961 | -0.0323 | Yes |
| 185 | Rps5 | 12389 | -0.969 | -0.0145 | Yes |
| 186 | Rps3 | 12404 | -1.024 | 0.0030 | Yes |

