| Dataset | Mast.Mast_Pheno.cls #Group1_versus_Group3.Mast_Pheno.cls #Group1_versus_Group3_repos |
| Phenotype | Mast_Pheno.cls#Group1_versus_Group3_repos |
| Upregulated in class | 0 |
| GeneSet | HALLMARK_G2M_CHECKPOINT |
| Enrichment Score (ES) | 0.17847738 |
| Normalized Enrichment Score (NES) | 0.75864273 |
| Nominal p-value | 0.88114756 |
| FDR q-value | 0.95336556 |
| FWER p-Value | 1.0 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Dmd | 131 | 0.774 | 0.0051 | Yes |
| 2 | Cks1b | 205 | 0.707 | 0.0136 | Yes |
| 3 | Ccnt1 | 280 | 0.658 | 0.0210 | Yes |
| 4 | Nasp | 283 | 0.654 | 0.0343 | Yes |
| 5 | Cdc7 | 294 | 0.650 | 0.0467 | Yes |
| 6 | Ndc80 | 336 | 0.628 | 0.0562 | Yes |
| 7 | Kif23 | 381 | 0.609 | 0.0651 | Yes |
| 8 | Ythdc1 | 654 | 0.518 | 0.0535 | Yes |
| 9 | Prc1 | 715 | 0.505 | 0.0589 | Yes |
| 10 | Pbk | 776 | 0.489 | 0.0640 | Yes |
| 11 | Cdkn1b | 988 | 0.444 | 0.0559 | Yes |
| 12 | Odf2 | 991 | 0.443 | 0.0648 | Yes |
| 13 | Slc12a2 | 1005 | 0.440 | 0.0727 | Yes |
| 14 | Hspa8 | 1034 | 0.432 | 0.0792 | Yes |
| 15 | Rasal2 | 1048 | 0.430 | 0.0870 | Yes |
| 16 | Incenp | 1063 | 0.426 | 0.0945 | Yes |
| 17 | Abl1 | 1119 | 0.417 | 0.0986 | Yes |
| 18 | Rbl1 | 1167 | 0.408 | 0.1031 | Yes |
| 19 | Slc38a1 | 1197 | 0.403 | 0.1089 | Yes |
| 20 | Mybl2 | 1344 | 0.379 | 0.1048 | Yes |
| 21 | Lmnb1 | 1377 | 0.375 | 0.1098 | Yes |
| 22 | Mcm2 | 1405 | 0.372 | 0.1152 | Yes |
| 23 | Plk1 | 1422 | 0.370 | 0.1215 | Yes |
| 24 | Exo1 | 1473 | 0.363 | 0.1248 | Yes |
| 25 | H2az1 | 1510 | 0.358 | 0.1292 | Yes |
| 26 | Rad21 | 1540 | 0.354 | 0.1341 | Yes |
| 27 | Cdk1 | 1741 | 0.328 | 0.1245 | Yes |
| 28 | Smad3 | 1783 | 0.324 | 0.1277 | Yes |
| 29 | Kpnb1 | 1789 | 0.323 | 0.1339 | Yes |
| 30 | Cdkn3 | 1839 | 0.316 | 0.1364 | Yes |
| 31 | Bard1 | 1848 | 0.316 | 0.1422 | Yes |
| 32 | Tmpo | 1860 | 0.314 | 0.1477 | Yes |
| 33 | Xpo1 | 1892 | 0.311 | 0.1516 | Yes |
| 34 | Gins2 | 1922 | 0.308 | 0.1555 | Yes |
| 35 | Hif1a | 1964 | 0.305 | 0.1584 | Yes |
| 36 | Cdc25a | 2029 | 0.298 | 0.1592 | Yes |
| 37 | Bub1 | 2041 | 0.298 | 0.1644 | Yes |
| 38 | Dtymk | 2165 | 0.284 | 0.1602 | Yes |
| 39 | Slc7a1 | 2179 | 0.282 | 0.1649 | Yes |
| 40 | Nsd2 | 2191 | 0.282 | 0.1698 | Yes |
| 41 | Smarcc1 | 2221 | 0.280 | 0.1731 | Yes |
| 42 | Notch2 | 2269 | 0.275 | 0.1749 | Yes |
| 43 | Slc7a5 | 2297 | 0.272 | 0.1783 | Yes |
| 44 | Sqle | 2376 | 0.267 | 0.1774 | Yes |
| 45 | Lbr | 2472 | 0.256 | 0.1749 | Yes |
| 46 | Ddx39a | 2553 | 0.250 | 0.1734 | Yes |
| 47 | Ctcf | 2643 | 0.241 | 0.1711 | Yes |
| 48 | Pttg1 | 2653 | 0.241 | 0.1753 | Yes |
| 49 | Pura | 2675 | 0.239 | 0.1785 | Yes |
| 50 | Uck2 | 2863 | 0.220 | 0.1677 | No |
| 51 | Upf1 | 2871 | 0.220 | 0.1716 | No |
| 52 | Racgap1 | 2902 | 0.217 | 0.1736 | No |
| 53 | Mad2l1 | 2971 | 0.212 | 0.1724 | No |
| 54 | Sfpq | 2994 | 0.210 | 0.1749 | No |
| 55 | Rpa2 | 3023 | 0.208 | 0.1769 | No |
| 56 | Nusap1 | 3129 | 0.199 | 0.1724 | No |
| 57 | Ezh2 | 3178 | 0.194 | 0.1724 | No |
| 58 | Fbxo5 | 3233 | 0.190 | 0.1719 | No |
| 59 | Cul5 | 3254 | 0.188 | 0.1741 | No |
| 60 | Tpx2 | 3320 | 0.182 | 0.1726 | No |
| 61 | Prpf4b | 3356 | 0.179 | 0.1734 | No |
| 62 | Traip | 3440 | 0.173 | 0.1701 | No |
| 63 | Nolc1 | 3463 | 0.171 | 0.1718 | No |
| 64 | Kif15 | 3641 | 0.157 | 0.1606 | No |
| 65 | Numa1 | 3777 | 0.145 | 0.1526 | No |
| 66 | Hnrnpd | 3807 | 0.143 | 0.1531 | No |
| 67 | Dbf4 | 3949 | 0.131 | 0.1443 | No |
| 68 | Tra2b | 4053 | 0.123 | 0.1384 | No |
| 69 | Sap30 | 4230 | 0.113 | 0.1263 | No |
| 70 | Top1 | 4286 | 0.108 | 0.1241 | No |
| 71 | Smc4 | 4411 | 0.100 | 0.1160 | No |
| 72 | Tfdp1 | 4441 | 0.098 | 0.1156 | No |
| 73 | Dr1 | 4449 | 0.097 | 0.1170 | No |
| 74 | Arid4a | 4456 | 0.097 | 0.1185 | No |
| 75 | Kif5b | 4505 | 0.094 | 0.1165 | No |
| 76 | Hnrnpu | 4523 | 0.092 | 0.1170 | No |
| 77 | Tle3 | 4605 | 0.085 | 0.1121 | No |
| 78 | Top2a | 4811 | 0.071 | 0.0968 | No |
| 79 | Cul1 | 4881 | 0.065 | 0.0925 | No |
| 80 | Smc2 | 4895 | 0.063 | 0.0928 | No |
| 81 | Srsf10 | 4930 | 0.061 | 0.0912 | No |
| 82 | Tacc3 | 5015 | 0.055 | 0.0855 | No |
| 83 | Mki67 | 5034 | 0.055 | 0.0852 | No |
| 84 | Cdkn2c | 5044 | 0.054 | 0.0855 | No |
| 85 | Nup98 | 5056 | 0.053 | 0.0857 | No |
| 86 | Chek1 | 5261 | 0.038 | 0.0699 | No |
| 87 | Chaf1a | 5288 | 0.036 | 0.0685 | No |
| 88 | Mcm5 | 5302 | 0.035 | 0.0681 | No |
| 89 | Srsf1 | 5472 | 0.024 | 0.0548 | No |
| 90 | Syncrip | 5484 | 0.023 | 0.0544 | No |
| 91 | E2f3 | 5681 | 0.012 | 0.0386 | No |
| 92 | Fancc | 5921 | -0.003 | 0.0192 | No |
| 93 | Dkc1 | 5966 | -0.008 | 0.0158 | No |
| 94 | Cdc27 | 5976 | -0.009 | 0.0152 | No |
| 95 | Hmmr | 6046 | -0.015 | 0.0099 | No |
| 96 | Stil | 6238 | -0.027 | -0.0051 | No |
| 97 | Pafah1b1 | 6264 | -0.029 | -0.0066 | No |
| 98 | Snrpd1 | 6267 | -0.029 | -0.0062 | No |
| 99 | Aurkb | 6303 | -0.031 | -0.0084 | No |
| 100 | Smc1a | 6457 | -0.041 | -0.0200 | No |
| 101 | Wrn | 6546 | -0.047 | -0.0262 | No |
| 102 | Tgfb1 | 6608 | -0.052 | -0.0302 | No |
| 103 | Gspt1 | 6803 | -0.064 | -0.0447 | No |
| 104 | Ccnb2 | 6886 | -0.070 | -0.0499 | No |
| 105 | Meis1 | 7110 | -0.086 | -0.0664 | No |
| 106 | Pds5b | 7143 | -0.089 | -0.0672 | No |
| 107 | Tnpo2 | 7208 | -0.093 | -0.0705 | No |
| 108 | Map3k20 | 7245 | -0.095 | -0.0715 | No |
| 109 | Cdc45 | 7291 | -0.097 | -0.0732 | No |
| 110 | Cenpf | 7294 | -0.098 | -0.0713 | No |
| 111 | Rad23b | 7333 | -0.100 | -0.0724 | No |
| 112 | Ccna2 | 7343 | -0.101 | -0.0711 | No |
| 113 | Atf5 | 7352 | -0.101 | -0.0697 | No |
| 114 | Kif22 | 7513 | -0.111 | -0.0805 | No |
| 115 | Kif20b | 7575 | -0.115 | -0.0831 | No |
| 116 | Rps6ka5 | 7612 | -0.118 | -0.0836 | No |
| 117 | Bcl3 | 7672 | -0.122 | -0.0859 | No |
| 118 | Knl1 | 7675 | -0.122 | -0.0836 | No |
| 119 | Cul4a | 7705 | -0.124 | -0.0834 | No |
| 120 | Mcm6 | 7730 | -0.126 | -0.0828 | No |
| 121 | Chmp1a | 7745 | -0.127 | -0.0814 | No |
| 122 | Ccnf | 7749 | -0.127 | -0.0790 | No |
| 123 | Nek2 | 7768 | -0.128 | -0.0779 | No |
| 124 | Kmt5a | 7905 | -0.139 | -0.0861 | No |
| 125 | Pola2 | 7926 | -0.140 | -0.0849 | No |
| 126 | Odc1 | 7949 | -0.142 | -0.0838 | No |
| 127 | Mapk14 | 8038 | -0.148 | -0.0880 | No |
| 128 | Cbx1 | 8068 | -0.150 | -0.0873 | No |
| 129 | Hmgb3 | 8075 | -0.150 | -0.0847 | No |
| 130 | Mnat1 | 8079 | -0.151 | -0.0819 | No |
| 131 | Kif4 | 8087 | -0.152 | -0.0793 | No |
| 132 | Pole | 8245 | -0.163 | -0.0888 | No |
| 133 | Kif2c | 8300 | -0.167 | -0.0898 | No |
| 134 | Ube2c | 8302 | -0.167 | -0.0865 | No |
| 135 | Espl1 | 8589 | -0.190 | -0.1059 | No |
| 136 | Atrx | 8628 | -0.193 | -0.1051 | No |
| 137 | E2f4 | 8680 | -0.195 | -0.1053 | No |
| 138 | Suv39h1 | 8696 | -0.197 | -0.1025 | No |
| 139 | Kif11 | 8850 | -0.207 | -0.1107 | No |
| 140 | Amd1 | 8897 | -0.211 | -0.1102 | No |
| 141 | Prim2 | 8943 | -0.214 | -0.1095 | No |
| 142 | Orc5 | 9098 | -0.225 | -0.1174 | No |
| 143 | G3bp1 | 9230 | -0.235 | -0.1233 | No |
| 144 | Bub3 | 9250 | -0.237 | -0.1200 | No |
| 145 | H2ax | 9253 | -0.237 | -0.1153 | No |
| 146 | Ss18 | 9310 | -0.242 | -0.1150 | No |
| 147 | Ilf3 | 9412 | -0.250 | -0.1181 | No |
| 148 | Cdc6 | 9514 | -0.259 | -0.1210 | No |
| 149 | Cdc25b | 9522 | -0.260 | -0.1163 | No |
| 150 | Marcks | 9537 | -0.262 | -0.1121 | No |
| 151 | Myc | 9576 | -0.265 | -0.1098 | No |
| 152 | Mcm3 | 9689 | -0.272 | -0.1133 | No |
| 153 | Jpt1 | 9727 | -0.276 | -0.1107 | No |
| 154 | Cenpa | 9851 | -0.287 | -0.1149 | No |
| 155 | E2f1 | 9869 | -0.288 | -0.1104 | No |
| 156 | E2f2 | 9964 | -0.297 | -0.1120 | No |
| 157 | Cdk4 | 10018 | -0.301 | -0.1101 | No |
| 158 | Tent4a | 10102 | -0.308 | -0.1106 | No |
| 159 | Hus1 | 10145 | -0.313 | -0.1076 | No |
| 160 | Aurka | 10154 | -0.314 | -0.1019 | No |
| 161 | Polq | 10180 | -0.316 | -0.0974 | No |
| 162 | Casp8ap2 | 10268 | -0.325 | -0.0979 | No |
| 163 | Brca2 | 10453 | -0.343 | -0.1059 | No |
| 164 | Stmn1 | 10491 | -0.347 | -0.1018 | No |
| 165 | Ncl | 10652 | -0.367 | -0.1074 | No |
| 166 | Rad54l | 10752 | -0.376 | -0.1078 | No |
| 167 | Lig3 | 10753 | -0.377 | -0.1001 | No |
| 168 | Plk4 | 10917 | -0.396 | -0.1053 | No |
| 169 | Cenpe | 10971 | -0.404 | -0.1013 | No |
| 170 | Pml | 11029 | -0.411 | -0.0976 | No |
| 171 | Troap | 11064 | -0.415 | -0.0919 | No |
| 172 | H2az2 | 11149 | -0.429 | -0.0899 | No |
| 173 | Cdc20 | 11233 | -0.442 | -0.0877 | No |
| 174 | Foxn3 | 11238 | -0.443 | -0.0789 | No |
| 175 | Ewsr1 | 11302 | -0.453 | -0.0748 | No |
| 176 | Nup50 | 11319 | -0.456 | -0.0668 | No |
| 177 | Ttk | 11462 | -0.478 | -0.0686 | No |
| 178 | Katna1 | 11499 | -0.486 | -0.0616 | No |
| 179 | Stag1 | 11574 | -0.503 | -0.0574 | No |
| 180 | Birc5 | 11594 | -0.507 | -0.0485 | No |
| 181 | Egf | 11599 | -0.509 | -0.0384 | No |
| 182 | Mtf2 | 11836 | -0.567 | -0.0461 | No |
| 183 | Srsf2 | 11941 | -0.606 | -0.0422 | No |
| 184 | Ube2s | 11944 | -0.608 | -0.0299 | No |
| 185 | Cul3 | 11976 | -0.623 | -0.0197 | No |
| 186 | Orc6 | 12103 | -0.666 | -0.0164 | No |
| 187 | Prmt5 | 12132 | -0.680 | -0.0048 | No |
| 188 | Hira | 12199 | -0.728 | 0.0047 | No |
| 189 | Cks2 | 12203 | -0.730 | 0.0194 | No |

