Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Mast.Mast_Pheno.cls #Group1_versus_Group2.Mast_Pheno.cls #Group1_versus_Group2_repos |
| Phenotype | Mast_Pheno.cls#Group1_versus_Group2_repos |
| Upregulated in class | 0 |
| GeneSet | HALLMARK_IL6_JAK_STAT3_SIGNALING |
| Enrichment Score (ES) | 0.20201035 |
| Normalized Enrichment Score (NES) | 0.7378613 |
| Nominal p-value | 0.87473905 |
| FDR q-value | 0.9536207 |
| FWER p-Value | 1.0 |
| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Cbl | 55 | 0.902 | 0.0671 | Yes |
| 2 | Tgfb1 | 427 | 0.586 | 0.0836 | Yes |
| 3 | Csf2ra | 450 | 0.577 | 0.1276 | Yes |
| 4 | Jun | 479 | 0.566 | 0.1703 | Yes |
| 5 | Cd44 | 634 | 0.522 | 0.1993 | Yes |
| 6 | Tnfrsf21 | 1032 | 0.439 | 0.2020 | Yes |
| 7 | Cd9 | 1677 | 0.346 | 0.1774 | No |
| 8 | Il17rb | 1906 | 0.318 | 0.1842 | No |
| 9 | Il3ra | 2170 | 0.292 | 0.1861 | No |
| 10 | Ptpn1 | 2594 | 0.255 | 0.1722 | No |
| 11 | Il2rg | 2710 | 0.245 | 0.1823 | No |
| 12 | Myd88 | 3184 | 0.207 | 0.1605 | No |
| 13 | Ifngr1 | 3490 | 0.183 | 0.1504 | No |
| 14 | Stat2 | 3681 | 0.170 | 0.1486 | No |
| 15 | Ptpn2 | 4119 | 0.140 | 0.1244 | No |
| 16 | Csf1 | 4145 | 0.138 | 0.1333 | No |
| 17 | Il10rb | 4183 | 0.135 | 0.1410 | No |
| 18 | Itgb3 | 4234 | 0.130 | 0.1473 | No |
| 19 | Il7 | 4604 | 0.107 | 0.1260 | No |
| 20 | Ltbr | 4813 | 0.094 | 0.1167 | No |
| 21 | Il6st | 5134 | 0.072 | 0.0966 | No |
| 22 | Il12rb1 | 5140 | 0.072 | 0.1018 | No |
| 23 | Ccr1 | 5332 | 0.059 | 0.0911 | No |
| 24 | Il17ra | 5753 | 0.030 | 0.0596 | No |
| 25 | Il15ra | 5795 | 0.027 | 0.0584 | No |
| 26 | Grb2 | 6017 | 0.013 | 0.0416 | No |
| 27 | Stat1 | 6159 | 0.003 | 0.0305 | No |
| 28 | Il4ra | 6585 | -0.024 | -0.0019 | No |
| 29 | Csf3r | 6672 | -0.028 | -0.0066 | No |
| 30 | Acvr1b | 6843 | -0.037 | -0.0174 | No |
| 31 | Tnfrsf1b | 6889 | -0.040 | -0.0178 | No |
| 32 | Irf9 | 6919 | -0.042 | -0.0168 | No |
| 33 | Tnf | 7183 | -0.061 | -0.0333 | No |
| 34 | Tyk2 | 7285 | -0.068 | -0.0360 | No |
| 35 | Ptpn11 | 7626 | -0.091 | -0.0562 | No |
| 36 | Il9r | 7672 | -0.093 | -0.0525 | No |
| 37 | Ifngr2 | 7991 | -0.115 | -0.0690 | No |
| 38 | Ltb | 8723 | -0.164 | -0.1150 | No |
| 39 | Stam2 | 9029 | -0.188 | -0.1247 | No |
| 40 | Irf1 | 9152 | -0.197 | -0.1189 | No |
| 41 | Pim1 | 9266 | -0.206 | -0.1118 | No |
| 42 | Il1r1 | 9405 | -0.216 | -0.1058 | No |
| 43 | Tnfrsf1a | 9932 | -0.257 | -0.1279 | No |
| 44 | Il6 | 9962 | -0.260 | -0.1096 | No |
| 45 | Itga4 | 10236 | -0.283 | -0.1092 | No |
| 46 | Pf4 | 10455 | -0.304 | -0.1027 | No |
| 47 | Crlf2 | 10492 | -0.309 | -0.0812 | No |
| 48 | Stat3 | 10598 | -0.321 | -0.0642 | No |
| 49 | Hax1 | 10630 | -0.325 | -0.0409 | No |
| 50 | Pik3r5 | 11006 | -0.374 | -0.0415 | No |
| 51 | Il1r2 | 11057 | -0.381 | -0.0153 | No |
| 52 | Ifnar1 | 11252 | -0.411 | 0.0016 | No |
| 53 | Il18r1 | 11757 | -0.498 | 0.0004 | No |
| 54 | Bak1 | 12258 | -0.690 | 0.0148 | No |
