| Dataset | Mast.Mast_Pheno.cls #Group1_versus_Group2.Mast_Pheno.cls #Group1_versus_Group2_repos |
| Phenotype | Mast_Pheno.cls#Group1_versus_Group2_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_G2M_CHECKPOINT |
| Enrichment Score (ES) | -0.2334256 |
| Normalized Enrichment Score (NES) | -0.9771537 |
| Nominal p-value | 0.49486652 |
| FDR q-value | 0.94137484 |
| FWER p-Value | 0.991 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Slc38a1 | 153 | 0.738 | 0.0028 | No |
| 2 | Cks1b | 200 | 0.707 | 0.0138 | No |
| 3 | Nasp | 309 | 0.631 | 0.0181 | No |
| 4 | Mcm2 | 422 | 0.589 | 0.0212 | No |
| 5 | Tgfb1 | 427 | 0.586 | 0.0330 | No |
| 6 | E2f4 | 573 | 0.541 | 0.0324 | No |
| 7 | Mybl2 | 648 | 0.520 | 0.0372 | No |
| 8 | Abl1 | 716 | 0.501 | 0.0422 | No |
| 9 | Cdkn1b | 834 | 0.476 | 0.0425 | No |
| 10 | Aurkb | 876 | 0.467 | 0.0489 | No |
| 11 | Bard1 | 931 | 0.456 | 0.0539 | No |
| 12 | Cbx1 | 947 | 0.453 | 0.0621 | No |
| 13 | Ythdc1 | 964 | 0.450 | 0.0702 | No |
| 14 | Bub1 | 1015 | 0.442 | 0.0753 | No |
| 15 | Rbl1 | 1038 | 0.437 | 0.0826 | No |
| 16 | Nolc1 | 1083 | 0.428 | 0.0879 | No |
| 17 | Rad21 | 1180 | 0.412 | 0.0886 | No |
| 18 | Kif22 | 1289 | 0.395 | 0.0880 | No |
| 19 | Srsf10 | 1423 | 0.379 | 0.0850 | No |
| 20 | Cul4a | 1495 | 0.369 | 0.0869 | No |
| 21 | Lmnb1 | 1559 | 0.361 | 0.0893 | No |
| 22 | Dbf4 | 1622 | 0.353 | 0.0915 | No |
| 23 | Tent4a | 1673 | 0.346 | 0.0946 | No |
| 24 | Mcm5 | 2071 | 0.302 | 0.0685 | No |
| 25 | Tacc3 | 2073 | 0.302 | 0.0747 | No |
| 26 | Wrn | 2086 | 0.301 | 0.0800 | No |
| 27 | Map3k20 | 2114 | 0.298 | 0.0840 | No |
| 28 | Nusap1 | 2138 | 0.295 | 0.0882 | No |
| 29 | Cdc45 | 2212 | 0.289 | 0.0882 | No |
| 30 | E2f3 | 2230 | 0.287 | 0.0928 | No |
| 31 | Dtymk | 2444 | 0.267 | 0.0810 | No |
| 32 | Espl1 | 2456 | 0.266 | 0.0856 | No |
| 33 | Top2a | 2551 | 0.257 | 0.0833 | No |
| 34 | Ctcf | 2552 | 0.257 | 0.0886 | No |
| 35 | Chaf1a | 2666 | 0.248 | 0.0846 | No |
| 36 | Cdc7 | 2819 | 0.235 | 0.0771 | No |
| 37 | H2az1 | 3094 | 0.214 | 0.0591 | No |
| 38 | Pbk | 3157 | 0.208 | 0.0584 | No |
| 39 | Fancc | 3209 | 0.205 | 0.0585 | No |
| 40 | Slc7a5 | 3229 | 0.203 | 0.0612 | No |
| 41 | Ccna2 | 3257 | 0.201 | 0.0632 | No |
| 42 | Uck2 | 3291 | 0.199 | 0.0646 | No |
| 43 | Notch2 | 3293 | 0.199 | 0.0686 | No |
| 44 | Chmp1a | 3376 | 0.191 | 0.0659 | No |
| 45 | Rpa2 | 3453 | 0.186 | 0.0636 | No |
| 46 | H2az2 | 3492 | 0.183 | 0.0643 | No |
| 47 | Suv39h1 | 3532 | 0.180 | 0.0648 | No |
| 48 | Slc12a2 | 3547 | 0.179 | 0.0674 | No |
| 49 | Stil | 3644 | 0.172 | 0.0632 | No |
| 50 | Mcm6 | 3660 | 0.171 | 0.0655 | No |
| 51 | Chek1 | 3686 | 0.169 | 0.0670 | No |
| 52 | Tnpo2 | 3764 | 0.164 | 0.0641 | No |
| 53 | Kpnb1 | 3831 | 0.159 | 0.0620 | No |
| 54 | Gspt1 | 3832 | 0.159 | 0.0653 | No |
| 55 | Cdc25a | 3995 | 0.148 | 0.0552 | No |
| 56 | Hif1a | 4039 | 0.144 | 0.0547 | No |
| 57 | Atrx | 4062 | 0.143 | 0.0558 | No |
| 58 | Smad3 | 4088 | 0.142 | 0.0568 | No |
| 59 | Mad2l1 | 4137 | 0.138 | 0.0557 | No |
| 60 | Snrpd1 | 4320 | 0.125 | 0.0435 | No |
| 61 | Sfpq | 4457 | 0.116 | 0.0348 | No |
| 62 | Foxn3 | 4513 | 0.113 | 0.0326 | No |
| 63 | Hnrnpd | 4715 | 0.100 | 0.0183 | No |
| 64 | Odc1 | 4798 | 0.094 | 0.0136 | No |
| 65 | E2f2 | 4802 | 0.094 | 0.0153 | No |
| 66 | Kif5b | 4841 | 0.092 | 0.0141 | No |
| 67 | Xpo1 | 4927 | 0.086 | 0.0089 | No |
| 68 | Dr1 | 4938 | 0.085 | 0.0099 | No |
| 69 | Cdkn3 | 5006 | 0.080 | 0.0061 | No |
| 70 | Rad23b | 5042 | 0.078 | 0.0049 | No |
| 71 | Marcks | 5060 | 0.076 | 0.0051 | No |
| 72 | Cdc6 | 5218 | 0.067 | -0.0064 | No |
| 73 | Hmgb3 | 5232 | 0.065 | -0.0061 | No |
| 74 | Traip | 5288 | 0.061 | -0.0093 | No |
| 75 | Fbxo5 | 5344 | 0.059 | -0.0126 | No |
| 76 | Gins2 | 5456 | 0.050 | -0.0206 | No |
| 77 | Mapk14 | 5467 | 0.049 | -0.0204 | No |
| 78 | Prpf4b | 5469 | 0.049 | -0.0195 | No |
| 79 | Nup98 | 5477 | 0.048 | -0.0190 | No |
| 80 | Pola2 | 5501 | 0.047 | -0.0199 | No |
| 81 | Dkc1 | 5834 | 0.025 | -0.0465 | No |
| 82 | Exo1 | 5857 | 0.024 | -0.0478 | No |
| 83 | Prc1 | 5862 | 0.023 | -0.0477 | No |
| 84 | Dmd | 6000 | 0.014 | -0.0585 | No |
| 85 | Mki67 | 6013 | 0.013 | -0.0592 | No |
| 86 | Ccnt1 | 6059 | 0.010 | -0.0627 | No |
| 87 | Smc2 | 6079 | 0.009 | -0.0641 | No |
| 88 | Nek2 | 6172 | 0.003 | -0.0715 | No |
| 89 | Sap30 | 6180 | 0.002 | -0.0721 | No |
| 90 | Katna1 | 6214 | 0.000 | -0.0747 | No |
| 91 | Aurka | 6240 | -0.001 | -0.0768 | No |
| 92 | Kmt5a | 6308 | -0.007 | -0.0821 | No |
| 93 | Tpx2 | 6390 | -0.011 | -0.0885 | No |
| 94 | Ndc80 | 6423 | -0.012 | -0.0908 | No |
| 95 | Rad54l | 6447 | -0.014 | -0.0924 | No |
| 96 | Kif11 | 6477 | -0.016 | -0.0945 | No |
| 97 | Ccnb2 | 6582 | -0.024 | -0.1025 | No |
| 98 | Cdc25b | 6903 | -0.041 | -0.1277 | No |
| 99 | Slc7a1 | 6976 | -0.047 | -0.1326 | No |
| 100 | Ddx39a | 7058 | -0.052 | -0.1382 | No |
| 101 | Syncrip | 7098 | -0.055 | -0.1402 | No |
| 102 | Racgap1 | 7147 | -0.058 | -0.1429 | No |
| 103 | Ss18 | 7305 | -0.069 | -0.1543 | No |
| 104 | Kif15 | 7341 | -0.071 | -0.1557 | No |
| 105 | Cdc20 | 7439 | -0.079 | -0.1620 | No |
| 106 | Smc1a | 7467 | -0.080 | -0.1625 | No |
| 107 | Atf5 | 7517 | -0.084 | -0.1647 | No |
| 108 | Upf1 | 7543 | -0.086 | -0.1650 | No |
| 109 | Smarcc1 | 7639 | -0.092 | -0.1708 | No |
| 110 | Cks2 | 7651 | -0.092 | -0.1698 | No |
| 111 | Hmmr | 7673 | -0.093 | -0.1696 | No |
| 112 | Pttg1 | 7914 | -0.110 | -0.1869 | No |
| 113 | Pml | 7915 | -0.110 | -0.1846 | No |
| 114 | Arid4a | 7939 | -0.112 | -0.1842 | No |
| 115 | G3bp1 | 8146 | -0.126 | -0.1984 | No |
| 116 | Sqle | 8200 | -0.130 | -0.2000 | No |
| 117 | Ube2c | 8201 | -0.130 | -0.1973 | No |
| 118 | Brca2 | 8216 | -0.130 | -0.1958 | No |
| 119 | Pole | 8260 | -0.133 | -0.1965 | No |
| 120 | Pura | 8421 | -0.144 | -0.2066 | No |
| 121 | Tmpo | 8451 | -0.146 | -0.2059 | No |
| 122 | Nsd2 | 8478 | -0.147 | -0.2050 | No |
| 123 | Stmn1 | 8527 | -0.150 | -0.2058 | No |
| 124 | Kif2c | 8621 | -0.157 | -0.2101 | No |
| 125 | H2ax | 8674 | -0.160 | -0.2111 | No |
| 126 | Odf2 | 8711 | -0.163 | -0.2106 | No |
| 127 | Ncl | 8734 | -0.164 | -0.2090 | No |
| 128 | Numa1 | 8738 | -0.165 | -0.2058 | No |
| 129 | Ewsr1 | 8838 | -0.174 | -0.2103 | No |
| 130 | Cul5 | 8897 | -0.178 | -0.2113 | No |
| 131 | Tra2b | 9090 | -0.193 | -0.2230 | No |
| 132 | Smc4 | 9112 | -0.195 | -0.2206 | No |
| 133 | Kif20b | 9162 | -0.198 | -0.2205 | No |
| 134 | Mnat1 | 9170 | -0.199 | -0.2169 | No |
| 135 | Rps6ka5 | 9351 | -0.212 | -0.2272 | Yes |
| 136 | Cul1 | 9356 | -0.212 | -0.2232 | Yes |
| 137 | Pafah1b1 | 9374 | -0.214 | -0.2201 | Yes |
| 138 | Tfdp1 | 9380 | -0.214 | -0.2161 | Yes |
| 139 | Kif4 | 9454 | -0.219 | -0.2175 | Yes |
| 140 | Incenp | 9477 | -0.221 | -0.2147 | Yes |
| 141 | Cdkn2c | 9532 | -0.226 | -0.2144 | Yes |
| 142 | Cdc27 | 9571 | -0.230 | -0.2127 | Yes |
| 143 | Nup50 | 9599 | -0.232 | -0.2101 | Yes |
| 144 | Ezh2 | 9621 | -0.233 | -0.2070 | Yes |
| 145 | Lbr | 9636 | -0.234 | -0.2033 | Yes |
| 146 | Top1 | 9639 | -0.234 | -0.1986 | Yes |
| 147 | E2f1 | 9779 | -0.245 | -0.2048 | Yes |
| 148 | Pds5b | 10015 | -0.264 | -0.2185 | Yes |
| 149 | Mtf2 | 10050 | -0.267 | -0.2157 | Yes |
| 150 | Cenpf | 10137 | -0.275 | -0.2170 | Yes |
| 151 | Lig3 | 10240 | -0.283 | -0.2195 | Yes |
| 152 | Kif23 | 10252 | -0.284 | -0.2145 | Yes |
| 153 | Ilf3 | 10256 | -0.285 | -0.2088 | Yes |
| 154 | Cul3 | 10311 | -0.290 | -0.2072 | Yes |
| 155 | Hnrnpu | 10385 | -0.297 | -0.2070 | Yes |
| 156 | Cenpa | 10451 | -0.303 | -0.2060 | Yes |
| 157 | Orc6 | 10683 | -0.331 | -0.2179 | Yes |
| 158 | Hspa8 | 10695 | -0.332 | -0.2119 | Yes |
| 159 | Ccnf | 10711 | -0.334 | -0.2062 | Yes |
| 160 | Stag1 | 11026 | -0.376 | -0.2240 | Yes |
| 161 | Plk1 | 11142 | -0.394 | -0.2252 | Yes |
| 162 | Myc | 11146 | -0.395 | -0.2173 | Yes |
| 163 | Cdk4 | 11279 | -0.414 | -0.2194 | Yes |
| 164 | Bub3 | 11304 | -0.418 | -0.2127 | Yes |
| 165 | Amd1 | 11325 | -0.422 | -0.2056 | Yes |
| 166 | Knl1 | 11337 | -0.424 | -0.1977 | Yes |
| 167 | Mcm3 | 11345 | -0.426 | -0.1894 | Yes |
| 168 | Hira | 11402 | -0.435 | -0.1849 | Yes |
| 169 | Srsf1 | 11437 | -0.440 | -0.1785 | Yes |
| 170 | Polq | 11445 | -0.442 | -0.1699 | Yes |
| 171 | Hus1 | 11479 | -0.447 | -0.1633 | Yes |
| 172 | Meis1 | 11718 | -0.491 | -0.1726 | Yes |
| 173 | Tle3 | 11720 | -0.491 | -0.1624 | Yes |
| 174 | Rasal2 | 11728 | -0.493 | -0.1528 | Yes |
| 175 | Bcl3 | 11730 | -0.493 | -0.1426 | Yes |
| 176 | Prim2 | 11790 | -0.507 | -0.1369 | Yes |
| 177 | Troap | 11857 | -0.523 | -0.1314 | Yes |
| 178 | Cdk1 | 11947 | -0.547 | -0.1273 | Yes |
| 179 | Birc5 | 12033 | -0.570 | -0.1224 | Yes |
| 180 | Casp8ap2 | 12042 | -0.575 | -0.1111 | Yes |
| 181 | Plk4 | 12133 | -0.609 | -0.1058 | Yes |
| 182 | Jpt1 | 12158 | -0.623 | -0.0948 | Yes |
| 183 | Cenpe | 12185 | -0.643 | -0.0836 | Yes |
| 184 | Ttk | 12220 | -0.659 | -0.0727 | Yes |
| 185 | Orc5 | 12284 | -0.714 | -0.0630 | Yes |
| 186 | Srsf2 | 12342 | -0.772 | -0.0516 | Yes |
| 187 | Ube2s | 12349 | -0.781 | -0.0359 | Yes |
| 188 | Prmt5 | 12388 | -0.856 | -0.0212 | Yes |
| 189 | Egf | 12435 | -1.223 | 0.0005 | Yes |

