Details for gene set HALLMARK_PI3K_AKT_MTOR

Table: GSEA Results Summary

Dataset	MPP.MPP_Pheno.cls#Group6_versus_Group8.MPP_Pheno.cls#Group6_versus_Group8_repos
Phenotype	MPP_Pheno.cls#Group6_versus_Group8_repos
Upregulated in class	5
GeneSet	HALLMARK_PI3K_AKT_MTOR_SIGNALING
Enrichment Score (ES)	-0.19087327
Normalized Enrichment Score (NES)	-0.9840485
Nominal p-value	0.48653847
FDR q-value	0.7293737
FWER p-Value	0.997

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Plcb1	21	1.139	0.0591	No
2	Lck	777	0.558	0.0497	No
3	Tsc2	1041	0.493	0.0622	No
4	Sfn	1683	0.423	0.0515	No
5	Prkar2a	1864	0.412	0.0640	No
6	Ralb	1996	0.402	0.0785	No
7	Pla2g12a	2275	0.369	0.0837	No
8	Sqstm1	2521	0.345	0.0893	No
9	Prkcb	2714	0.326	0.0966	No
10	Trib3	2790	0.320	0.1097	No
11	Acaca	3109	0.299	0.1091	No
12	Adcy2	3259	0.290	0.1167	No
13	Prkaa2	3424	0.279	0.1230	No
14	Tiam1	4262	0.246	0.0929	No
15	Ptpn11	4320	0.243	0.1028	No
16	Ripk1	5303	0.189	0.0622	No
17	Pin1	5335	0.188	0.0705	No
18	Plcg1	5358	0.186	0.0792	No
19	E2f1	5545	0.177	0.0790	No
20	Ppp2r1b	5683	0.171	0.0810	No
21	Map2k3	5904	0.160	0.0781	No
22	Pikfyve	6124	0.150	0.0747	No
23	Raf1	6129	0.149	0.0824	No
24	Pak4	6431	0.135	0.0740	No
25	Ap2m1	6712	0.121	0.0660	No
26	Arhgdia	6801	0.118	0.0677	No
27	Mapk9	6914	0.113	0.0680	No
28	Tbk1	7095	0.105	0.0643	No
29	Hsp90b1	8181	0.062	0.0116	No
30	Grk2	8461	0.052	0.0000	No
31	Il4	8466	0.052	0.0025	No
32	Nod1	8799	0.039	-0.0125	No
33	Cxcr4	8865	0.036	-0.0139	No
34	Ywhab	8879	0.036	-0.0127	No
35	Vav3	8975	0.032	-0.0159	No
36	Gsk3b	9303	0.020	-0.0317	No
37	Rptor	9314	0.020	-0.0312	No
38	Actr2	9327	0.019	-0.0308	No
39	Mapk8	9362	0.018	-0.0316	No
40	Smad2	9390	0.017	-0.0321	No
41	Ube2n	9423	0.015	-0.0330	No
42	Eif4e	9744	0.003	-0.0493	No
43	Mknk2	10276	-0.004	-0.0764	No
44	Cdk2	10366	-0.007	-0.0807	No
45	Pitx2	10394	-0.007	-0.0817	No
46	Prkag1	10442	-0.009	-0.0836	No
47	Cdk4	10448	-0.009	-0.0834	No
48	Mapk1	10658	-0.014	-0.0934	No
49	Itpr2	10726	-0.017	-0.0960	No
50	Rps6ka3	10939	-0.026	-0.1055	No
51	Cdkn1a	10951	-0.026	-0.1047	No
52	Pfn1	10968	-0.027	-0.1041	No
53	Map2k6	11247	-0.037	-0.1164	No
54	Sla	11317	-0.040	-0.1179	No
55	Tnfrsf1a	11353	-0.041	-0.1175	No
56	Pdk1	11600	-0.050	-0.1276	No
57	Mapkap1	11682	-0.053	-0.1290	No
58	Camk4	11694	-0.053	-0.1267	No
59	Akt1s1	11973	-0.064	-0.1376	No
60	Ube2d3	12019	-0.066	-0.1364	No
61	Nfkbib	12151	-0.072	-0.1394	No
62	Arpc3	12394	-0.079	-0.1476	No
63	Cab39	13018	-0.105	-0.1742	No
64	Pten	13212	-0.111	-0.1782	No
65	Them4	13271	-0.114	-0.1752	No
66	Mapk10	13335	-0.117	-0.1723	No
67	Rac1	13352	-0.117	-0.1669	No
68	Grb2	13566	-0.127	-0.1712	No
69	Cab39l	13840	-0.139	-0.1779	No
70	Cdk1	14093	-0.150	-0.1830	Yes
71	Cltc	14118	-0.151	-0.1762	Yes
72	Arf1	14126	-0.152	-0.1686	Yes
73	Il2rg	14152	-0.153	-0.1618	Yes
74	Dapp1	14291	-0.160	-0.1604	Yes
75	Nck1	14510	-0.170	-0.1627	Yes
76	Map3k7	14617	-0.175	-0.1589	Yes
77	Atf1	14623	-0.175	-0.1499	Yes
78	Dusp3	14659	-0.177	-0.1424	Yes
79	Ecsit	14886	-0.189	-0.1440	Yes
80	Rps6ka1	15056	-0.199	-0.1422	Yes
81	Stat2	15178	-0.205	-0.1376	Yes
82	Irak4	15524	-0.223	-0.1436	Yes
83	Actr3	15654	-0.230	-0.1381	Yes
84	Akt1	15850	-0.242	-0.1354	Yes
85	Ppp1ca	16029	-0.252	-0.1312	Yes
86	Traf2	16247	-0.267	-0.1283	Yes
87	Myd88	16752	-0.296	-0.1386	Yes
88	Calr	17067	-0.312	-0.1383	Yes
89	Cdkn1b	17224	-0.324	-0.1292	Yes
90	Mknk1	17392	-0.333	-0.1202	Yes
91	Pik3r3	18455	-0.455	-0.1508	Yes
92	Csnk2b	18473	-0.459	-0.1274	Yes
93	Rit1	18502	-0.463	-0.1044	Yes
94	Gna14	18824	-0.515	-0.0937	Yes
95	Cfl1	18879	-0.524	-0.0688	Yes
96	Hras	19031	-0.565	-0.0467	Yes
97	Ddit3	19218	-0.646	-0.0222	Yes
98	Slc2a1	19320	-0.705	0.0099	Yes