Details for gene set HALLMARK_P53

Table: GSEA Results Summary

Dataset	MPP.MPP_Pheno.cls#Group6_versus_Group8.MPP_Pheno.cls#Group6_versus_Group8_repos
Phenotype	MPP_Pheno.cls#Group6_versus_Group8_repos
Upregulated in class	5
GeneSet	HALLMARK_P53_PATHWAY
Enrichment Score (ES)	-0.2397729
Normalized Enrichment Score (NES)	-1.0771941
Nominal p-value	0.29568788
FDR q-value	0.630893
FWER p-Value	0.98

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Klf4	38	1.039	0.0216	No
2	Ddb2	164	0.784	0.0329	No
3	Ptpn14	713	0.575	0.0175	No
4	Procr	770	0.560	0.0273	No
5	Fos	874	0.530	0.0340	No
6	Ninj1	896	0.524	0.0448	No
7	Zmat3	984	0.502	0.0516	No
8	Ccp110	1147	0.474	0.0540	No
9	Fam162a	1247	0.461	0.0593	No
10	Sfn	1683	0.423	0.0464	No
11	Coq8a	1860	0.413	0.0467	No
12	Trp63	1932	0.409	0.0522	No
13	Pidd1	2057	0.393	0.0547	No
14	Cgrrf1	2063	0.392	0.0634	No
15	Rad51c	2073	0.391	0.0717	No
16	Pom121	2219	0.374	0.0727	No
17	Hexim1	2267	0.369	0.0787	No
18	Jag2	2380	0.358	0.0810	No
19	Traf4	2589	0.337	0.0778	No
20	Rxra	2626	0.334	0.0836	No
21	Apaf1	2649	0.332	0.0899	No
22	H2ac25	2698	0.328	0.0949	No
23	Trib3	2790	0.320	0.0974	No
24	Rad9a	2967	0.307	0.0953	No
25	Aen	2987	0.306	0.1012	No
26	Tspyl2	3082	0.301	0.1032	No
27	Sp1	3108	0.299	0.1086	No
28	Epha2	3264	0.289	0.1072	No
29	Lif	3456	0.277	0.1036	No
30	Pvt1	3786	0.263	0.0925	No
31	Ralgds	3859	0.258	0.0946	No
32	Bax	3881	0.256	0.0993	No
33	Polh	3944	0.253	0.1018	No
34	Alox8	4130	0.251	0.0980	No
35	Ada	4234	0.248	0.0982	No
36	Slc3a2	4280	0.245	0.1015	No
37	Foxo3	4625	0.229	0.0889	No
38	Rrad	4643	0.228	0.0931	No
39	Ifi30	4691	0.225	0.0958	No
40	Tsc22d1	4830	0.217	0.0936	No
41	Tob1	4911	0.212	0.0942	No
42	Slc7a11	5022	0.206	0.0932	No
43	Hdac3	5185	0.197	0.0893	No
44	H1f2	5186	0.197	0.0937	No
45	Nupr1	5526	0.178	0.0803	No
46	Gls2	5636	0.173	0.0785	No
47	Fgf13	5716	0.170	0.0783	No
48	Jun	5804	0.164	0.0775	No
49	Ldhb	5877	0.161	0.0774	No
50	Ppm1d	5958	0.158	0.0769	No
51	Hint1	6099	0.151	0.0731	No
52	Cdkn2aip	6245	0.144	0.0688	No
53	Ephx1	6246	0.144	0.0721	No
54	Cyfip2	6263	0.143	0.0745	No
55	Irag2	6304	0.141	0.0756	No
56	Pcna	6321	0.140	0.0779	No
57	Steap3	6362	0.138	0.0790	No
58	Vwa5a	6382	0.137	0.0811	No
59	Cdh13	6497	0.132	0.0782	No
60	Itgb4	6791	0.119	0.0657	No
61	Mdm2	6867	0.115	0.0644	No
62	Irak1	6937	0.112	0.0634	No
63	Plk2	7080	0.106	0.0585	No
64	Ppp1r15a	7201	0.101	0.0546	No
65	Pmm1	7425	0.091	0.0451	No
66	Perp	7462	0.090	0.0452	No
67	Ccnd3	7503	0.088	0.0452	No
68	Prkab1	7507	0.088	0.0470	No
69	Fbxw7	7831	0.076	0.0320	No
70	Ier5	8084	0.065	0.0204	No
71	Ddit4	8089	0.065	0.0217	No
72	Tcn2	8116	0.064	0.0218	No
73	Fas	8752	0.041	-0.0101	No
74	Sesn1	8840	0.037	-0.0138	No
75	Txnip	8915	0.035	-0.0168	No
76	Nol8	8917	0.035	-0.0161	No
77	Elp1	8973	0.032	-0.0182	No
78	St14	9005	0.031	-0.0191	No
79	Vamp8	9245	0.022	-0.0310	No
80	Rrp8	9399	0.016	-0.0385	No
81	Socs1	9428	0.015	-0.0396	No
82	Upp1	9550	0.010	-0.0457	No
83	Wwp1	9609	0.008	-0.0485	No
84	Vdr	9617	0.008	-0.0487	No
85	Ercc5	9656	0.006	-0.0505	No
86	App	9828	0.000	-0.0593	No
87	Osgin1	10203	-0.001	-0.0787	No
88	Atf3	10243	-0.003	-0.0806	No
89	Btg2	10271	-0.003	-0.0819	No
90	Mknk2	10276	-0.004	-0.0821	No
91	Pdgfa	10294	-0.005	-0.0829	No
92	Dcxr	10426	-0.008	-0.0894	No
93	Hspa4l	10450	-0.009	-0.0904	No
94	Cdk5r1	10621	-0.014	-0.0989	No
95	Sat1	10700	-0.016	-0.1026	No
96	Ccnd2	10731	-0.017	-0.1038	No
97	Cdkn1a	10951	-0.026	-0.1145	No
98	Wrap73	11103	-0.032	-0.1216	No
99	Kif13b	11188	-0.035	-0.1251	No
100	Ccng1	11273	-0.038	-0.1286	No
101	Prmt2	11416	-0.044	-0.1350	No
102	Xpc	11521	-0.047	-0.1393	No
103	Tgfa	11832	-0.058	-0.1540	No
104	Cd81	11867	-0.060	-0.1544	No
105	Ptpre	11919	-0.062	-0.1556	No
106	Plk3	11972	-0.064	-0.1569	No
107	F2r	12212	-0.075	-0.1675	No
108	Fdxr	12267	-0.076	-0.1686	No
109	Notch1	12296	-0.077	-0.1683	No
110	Pitpnc1	12300	-0.077	-0.1667	No
111	Def6	12553	-0.086	-0.1778	No
112	Dnttip2	12678	-0.091	-0.1822	No
113	Ctsd	12819	-0.097	-0.1872	No
114	Blcap	12849	-0.098	-0.1865	No
115	Ccnk	12867	-0.099	-0.1851	No
116	Sphk1	12894	-0.100	-0.1842	No
117	Casp1	13050	-0.106	-0.1898	No
118	Dgka	13051	-0.106	-0.1874	No
119	Slc35d1	13276	-0.114	-0.1964	No
120	Btg1	13354	-0.117	-0.1978	No
121	Baiap2	13402	-0.120	-0.1975	No
122	Rab40c	13481	-0.123	-0.1987	No
123	Plxnb2	13707	-0.134	-0.2074	No
124	Ak1	13720	-0.134	-0.2049	No
125	Mapkapk3	13827	-0.138	-0.2073	No
126	S100a10	13844	-0.139	-0.2050	No
127	Tgfb1	14198	-0.155	-0.2197	No
128	Abcc5	14243	-0.157	-0.2184	No
129	Dram1	14365	-0.163	-0.2210	No
130	Phlda3	14378	-0.164	-0.2179	No
131	H2aj	14438	-0.167	-0.2172	No
132	Sertad3	14460	-0.168	-0.2145	No
133	Rb1	14587	-0.174	-0.2170	No
134	Hbegf	14685	-0.178	-0.2180	No
135	Cebpa	14695	-0.178	-0.2145	No
136	Zfp36l1	14715	-0.179	-0.2114	No
137	Rhbdf2	14738	-0.180	-0.2085	No
138	Ei24	14782	-0.182	-0.2066	No
139	Sec61a1	15043	-0.198	-0.2155	No
140	Tpd52l1	15068	-0.200	-0.2122	No
141	Trp53	15084	-0.201	-0.2085	No
142	Retsat	15197	-0.206	-0.2096	No
143	Rpl36	15225	-0.208	-0.2063	No
144	Fuca1	15568	-0.225	-0.2189	No
145	Rap2b	15873	-0.243	-0.2291	No
146	Triap1	15876	-0.244	-0.2237	No
147	Abhd4	15877	-0.244	-0.2181	No
148	Ier3	15965	-0.249	-0.2170	No
149	Cdkn2a	16133	-0.260	-0.2198	No
150	Nudt15	16216	-0.265	-0.2180	No
151	Eps8l2	16614	-0.287	-0.2320	No
152	Ankra2	16754	-0.296	-0.2325	No
153	Ndrg1	16895	-0.304	-0.2329	Yes
154	Tm7sf3	16933	-0.306	-0.2279	Yes
155	Klk8	17085	-0.314	-0.2286	Yes
156	Mxd4	17112	-0.316	-0.2228	Yes
157	Sdc1	17129	-0.317	-0.2164	Yes
158	Zfp365	17142	-0.319	-0.2098	Yes
159	Trafd1	17228	-0.325	-0.2069	Yes
160	Acvr1b	17373	-0.332	-0.2068	Yes
161	Zbtb16	17461	-0.340	-0.2036	Yes
162	Ip6k2	17516	-0.346	-0.1985	Yes
163	Tap1	17939	-0.385	-0.2116	Yes
164	Bak1	18021	-0.395	-0.2069	Yes
165	Rps27l	18060	-0.400	-0.1998	Yes
166	Gm2a	18119	-0.407	-0.1936	Yes
167	Abat	18184	-0.416	-0.1875	Yes
168	S100a4	18232	-0.422	-0.1803	Yes
169	Tprkb	18244	-0.423	-0.1713	Yes
170	Rack1	18422	-0.450	-0.1702	Yes
171	Hmox1	18451	-0.455	-0.1614	Yes
172	Gadd45a	18452	-0.455	-0.1511	Yes
173	Slc19a2	18647	-0.484	-0.1501	Yes
174	Rnf19b	18691	-0.492	-0.1412	Yes
175	Rchy1	18743	-0.503	-0.1325	Yes
176	Ctsf	18841	-0.518	-0.1257	Yes
177	Stom	18961	-0.544	-0.1196	Yes
178	Cd82	18978	-0.547	-0.1080	Yes
179	Csrnp2	19002	-0.556	-0.0966	Yes
180	Hras	19031	-0.565	-0.0853	Yes
181	Tnfsf9	19044	-0.569	-0.0730	Yes
182	Rps12	19098	-0.592	-0.0623	Yes
183	Ddit3	19218	-0.646	-0.0538	Yes
184	Mxd1	19337	-0.715	-0.0437	Yes
185	Tax1bp3	19374	-0.745	-0.0287	Yes
186	Iscu	19392	-0.764	-0.0123	Yes
187	Rpl18	19435	-0.815	0.0040	Yes