| Dataset | MPP.MPP_Pheno.cls#Group6_versus_Group8.MPP_Pheno.cls#Group6_versus_Group8_repos |
| Phenotype | MPP_Pheno.cls#Group6_versus_Group8_repos |
| Upregulated in class | 5 |
| GeneSet | HALLMARK_MYC_TARGETS_V1 |
| Enrichment Score (ES) | -0.31354702 |
| Normalized Enrichment Score (NES) | -1.2560018 |
| Nominal p-value | 0.25426945 |
| FDR q-value | 0.3870671 |
| FWER p-Value | 0.886 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Cdc45 | 57 | 0.979 | 0.0228 | No |
| 2 | Prps2 | 341 | 0.658 | 0.0255 | No |
| 3 | Odc1 | 355 | 0.653 | 0.0420 | No |
| 4 | Snrpa | 826 | 0.544 | 0.0320 | No |
| 5 | Dut | 1143 | 0.475 | 0.0282 | No |
| 6 | Ifrd1 | 2343 | 0.362 | -0.0243 | No |
| 7 | Mcm4 | 2376 | 0.359 | -0.0165 | No |
| 8 | Eif2s1 | 2668 | 0.330 | -0.0229 | No |
| 9 | Etf1 | 2961 | 0.307 | -0.0299 | No |
| 10 | Kpnb1 | 3037 | 0.302 | -0.0258 | No |
| 11 | Tra2b | 3097 | 0.300 | -0.0210 | No |
| 12 | Xpot | 3125 | 0.298 | -0.0146 | No |
| 13 | Pold2 | 3176 | 0.294 | -0.0094 | No |
| 14 | Hspd1 | 3225 | 0.291 | -0.0042 | No |
| 15 | Ptges3-ps | 3539 | 0.275 | -0.0132 | No |
| 16 | Hnrnpu | 3669 | 0.266 | -0.0129 | No |
| 17 | Pgk1 | 4261 | 0.246 | -0.0370 | No |
| 18 | Mcm6 | 4407 | 0.237 | -0.0382 | No |
| 19 | Ruvbl2 | 4554 | 0.234 | -0.0396 | No |
| 20 | Mrps18b | 4827 | 0.217 | -0.0480 | No |
| 21 | Cstf2 | 4874 | 0.215 | -0.0447 | No |
| 22 | Nop56 | 5079 | 0.202 | -0.0500 | No |
| 23 | Smarcc1 | 5190 | 0.197 | -0.0505 | No |
| 24 | Hnrnpa3 | 5243 | 0.193 | -0.0481 | No |
| 25 | Mcm5 | 5374 | 0.186 | -0.0499 | No |
| 26 | Tfdp1 | 5505 | 0.179 | -0.0519 | No |
| 27 | Srpk1 | 5509 | 0.179 | -0.0474 | No |
| 28 | Pwp1 | 5592 | 0.175 | -0.0470 | No |
| 29 | Eif4h | 5676 | 0.171 | -0.0468 | No |
| 30 | Srsf2 | 5931 | 0.159 | -0.0558 | No |
| 31 | Tufm | 5932 | 0.159 | -0.0516 | No |
| 32 | Eif3d | 5946 | 0.159 | -0.0481 | No |
| 33 | Psma6 | 5979 | 0.157 | -0.0456 | No |
| 34 | Xrcc6 | 6009 | 0.156 | -0.0430 | No |
| 35 | Ddx21 | 6015 | 0.155 | -0.0391 | No |
| 36 | Rps6 | 6198 | 0.146 | -0.0447 | No |
| 37 | Pcna | 6321 | 0.140 | -0.0474 | No |
| 38 | Ywhaq | 6472 | 0.133 | -0.0516 | No |
| 39 | Prdx4 | 6554 | 0.130 | -0.0524 | No |
| 40 | Srsf7 | 6703 | 0.122 | -0.0569 | No |
| 41 | Psmb2 | 6763 | 0.120 | -0.0568 | No |
| 42 | Txnl4a | 6873 | 0.115 | -0.0594 | No |
| 43 | Pa2g4 | 6916 | 0.113 | -0.0586 | No |
| 44 | Fbl | 6927 | 0.113 | -0.0561 | No |
| 45 | Erh | 6928 | 0.113 | -0.0531 | No |
| 46 | Pole3 | 7168 | 0.102 | -0.0628 | No |
| 47 | Fam120a | 7194 | 0.101 | -0.0615 | No |
| 48 | Mrpl23 | 7206 | 0.100 | -0.0594 | No |
| 49 | Mrpl9 | 7210 | 0.100 | -0.0569 | No |
| 50 | Rad23b | 7322 | 0.096 | -0.0601 | No |
| 51 | Ranbp1 | 7604 | 0.085 | -0.0724 | No |
| 52 | Ccna2 | 7641 | 0.083 | -0.0721 | No |
| 53 | Xpo1 | 7878 | 0.073 | -0.0824 | No |
| 54 | Nap1l1 | 8095 | 0.065 | -0.0919 | No |
| 55 | Cct5 | 8101 | 0.065 | -0.0904 | No |
| 56 | Syncrip | 8115 | 0.064 | -0.0894 | No |
| 57 | Hddc2 | 8144 | 0.063 | -0.0892 | No |
| 58 | Clns1a | 8240 | 0.059 | -0.0926 | No |
| 59 | Srsf3 | 8337 | 0.056 | -0.0960 | No |
| 60 | Vdac3 | 8504 | 0.050 | -0.1033 | No |
| 61 | Rsl1d1 | 8546 | 0.049 | -0.1042 | No |
| 62 | Tomm70a | 8575 | 0.048 | -0.1044 | No |
| 63 | Hnrnpr | 8707 | 0.043 | -0.1100 | No |
| 64 | Psmc6 | 9009 | 0.031 | -0.1248 | No |
| 65 | Prpf31 | 9011 | 0.031 | -0.1240 | No |
| 66 | Slc25a3 | 9096 | 0.028 | -0.1276 | No |
| 67 | Rpl22 | 9442 | 0.015 | -0.1451 | No |
| 68 | G3bp1 | 9461 | 0.014 | -0.1457 | No |
| 69 | Hnrnpa1 | 9475 | 0.013 | -0.1460 | No |
| 70 | Cad | 9477 | 0.013 | -0.1457 | No |
| 71 | Sf3b3 | 9513 | 0.012 | -0.1472 | No |
| 72 | Nolc1 | 9601 | 0.008 | -0.1515 | No |
| 73 | Hdac2 | 9613 | 0.008 | -0.1518 | No |
| 74 | Mcm7 | 9664 | 0.006 | -0.1543 | No |
| 75 | Hnrnpd | 9716 | 0.004 | -0.1568 | No |
| 76 | Eif4e | 9744 | 0.003 | -0.1581 | No |
| 77 | Dhx15 | 9799 | 0.001 | -0.1609 | No |
| 78 | Gm9531 | 9819 | 0.000 | -0.1619 | No |
| 79 | Ywhae | 9827 | 0.000 | -0.1622 | No |
| 80 | Ssb | 10334 | -0.006 | -0.1883 | No |
| 81 | Cdk2 | 10366 | -0.007 | -0.1897 | No |
| 82 | Psmd14 | 10416 | -0.008 | -0.1920 | No |
| 83 | Cdk4 | 10448 | -0.009 | -0.1934 | No |
| 84 | Psma4 | 10587 | -0.012 | -0.2002 | No |
| 85 | Canx | 10667 | -0.014 | -0.2039 | No |
| 86 | Ndufab1 | 10682 | -0.015 | -0.2042 | No |
| 87 | Eif4a1 | 10722 | -0.016 | -0.2058 | No |
| 88 | Cct2 | 10805 | -0.020 | -0.2095 | No |
| 89 | Eif3j1 | 11129 | -0.033 | -0.2254 | No |
| 90 | Psmb3 | 11174 | -0.035 | -0.2267 | No |
| 91 | Uba2 | 11196 | -0.035 | -0.2269 | No |
| 92 | Cops5 | 11237 | -0.037 | -0.2280 | No |
| 93 | Psma7 | 11337 | -0.041 | -0.2320 | No |
| 94 | Hnrnpa2b1 | 11370 | -0.042 | -0.2326 | No |
| 95 | Stard7 | 11380 | -0.042 | -0.2319 | No |
| 96 | Hnrnpc | 11383 | -0.043 | -0.2309 | No |
| 97 | Psmd1 | 11482 | -0.045 | -0.2348 | No |
| 98 | Cul1 | 11511 | -0.047 | -0.2350 | No |
| 99 | Gnl3 | 11515 | -0.047 | -0.2339 | No |
| 100 | Hsp90ab1 | 11650 | -0.052 | -0.2395 | No |
| 101 | Rrm1 | 11782 | -0.056 | -0.2448 | No |
| 102 | Psmd3 | 12005 | -0.066 | -0.2546 | No |
| 103 | Tyms | 12125 | -0.071 | -0.2589 | No |
| 104 | Orc2 | 12252 | -0.076 | -0.2634 | No |
| 105 | Mcm2 | 12347 | -0.078 | -0.2662 | No |
| 106 | Srm | 12449 | -0.081 | -0.2693 | No |
| 107 | Pabpc1 | 12452 | -0.081 | -0.2672 | No |
| 108 | Lsm2 | 12593 | -0.087 | -0.2722 | No |
| 109 | Ran | 12608 | -0.088 | -0.2706 | No |
| 110 | Eif4g2 | 12785 | -0.096 | -0.2772 | No |
| 111 | Srsf1 | 12818 | -0.097 | -0.2763 | No |
| 112 | Rfc4 | 12889 | -0.100 | -0.2773 | No |
| 113 | Ube2e1 | 13062 | -0.107 | -0.2834 | No |
| 114 | Mad2l1 | 13089 | -0.107 | -0.2819 | No |
| 115 | Sf3a1 | 13307 | -0.116 | -0.2901 | No |
| 116 | Cct4 | 13412 | -0.120 | -0.2923 | No |
| 117 | Tardbp | 13517 | -0.125 | -0.2944 | No |
| 118 | Usp1 | 13567 | -0.127 | -0.2936 | No |
| 119 | Aimp2 | 13769 | -0.136 | -0.3004 | No |
| 120 | Eif2s2 | 13851 | -0.139 | -0.3009 | No |
| 121 | Rnps1 | 13941 | -0.143 | -0.3018 | No |
| 122 | Rpl14 | 13968 | -0.144 | -0.2993 | No |
| 123 | Serbp1 | 14165 | -0.154 | -0.3054 | No |
| 124 | Snrpa1 | 14241 | -0.157 | -0.3052 | No |
| 125 | Impdh2 | 14404 | -0.165 | -0.3092 | Yes |
| 126 | Dek | 14467 | -0.168 | -0.3080 | Yes |
| 127 | Myc | 14566 | -0.173 | -0.3085 | Yes |
| 128 | Psmd7 | 14586 | -0.174 | -0.3049 | Yes |
| 129 | Ddx18 | 14649 | -0.176 | -0.3035 | Yes |
| 130 | Cnbp | 14700 | -0.178 | -0.3014 | Yes |
| 131 | Gspt1 | 14772 | -0.182 | -0.3003 | Yes |
| 132 | Nhp2 | 14789 | -0.183 | -0.2963 | Yes |
| 133 | Cct7 | 14793 | -0.183 | -0.2916 | Yes |
| 134 | H2az1 | 14829 | -0.185 | -0.2886 | Yes |
| 135 | Exosc7 | 15115 | -0.202 | -0.2980 | Yes |
| 136 | Ncbp1 | 15163 | -0.204 | -0.2950 | Yes |
| 137 | Pabpc4 | 15222 | -0.207 | -0.2926 | Yes |
| 138 | Ncbp2 | 15406 | -0.217 | -0.2963 | Yes |
| 139 | Ldha | 15503 | -0.222 | -0.2955 | Yes |
| 140 | Eif3b | 15570 | -0.226 | -0.2929 | Yes |
| 141 | Psma2 | 15593 | -0.227 | -0.2881 | Yes |
| 142 | Nme1 | 15702 | -0.233 | -0.2876 | Yes |
| 143 | C1qbp | 15737 | -0.235 | -0.2831 | Yes |
| 144 | Npm1 | 15830 | -0.240 | -0.2816 | Yes |
| 145 | Abce1 | 16005 | -0.251 | -0.2840 | Yes |
| 146 | Trim28 | 16062 | -0.255 | -0.2802 | Yes |
| 147 | Bub3 | 16074 | -0.255 | -0.2740 | Yes |
| 148 | Rps5 | 16083 | -0.256 | -0.2677 | Yes |
| 149 | Nop16 | 16143 | -0.260 | -0.2639 | Yes |
| 150 | Ssbp1 | 16171 | -0.261 | -0.2584 | Yes |
| 151 | Cct3 | 16372 | -0.269 | -0.2617 | Yes |
| 152 | Hdgf | 16452 | -0.275 | -0.2585 | Yes |
| 153 | Tcp1 | 16575 | -0.285 | -0.2574 | Yes |
| 154 | Psmc4 | 16630 | -0.288 | -0.2526 | Yes |
| 155 | Phb2 | 16672 | -0.290 | -0.2471 | Yes |
| 156 | Vdac1 | 16751 | -0.296 | -0.2433 | Yes |
| 157 | Snrpd1 | 16772 | -0.298 | -0.2365 | Yes |
| 158 | Rpl6 | 16939 | -0.307 | -0.2370 | Yes |
| 159 | Prdx3 | 17073 | -0.313 | -0.2357 | Yes |
| 160 | Snrpd2 | 17140 | -0.319 | -0.2307 | Yes |
| 161 | Pcbp1 | 17435 | -0.338 | -0.2370 | Yes |
| 162 | Cbx3 | 17635 | -0.357 | -0.2379 | Yes |
| 163 | Rplp0 | 17676 | -0.359 | -0.2305 | Yes |
| 164 | Ppia | 17724 | -0.362 | -0.2234 | Yes |
| 165 | Psmd8 | 17852 | -0.374 | -0.2202 | Yes |
| 166 | Eef1b2 | 17907 | -0.382 | -0.2129 | Yes |
| 167 | Snrpd3 | 17920 | -0.383 | -0.2034 | Yes |
| 168 | Acp1 | 17942 | -0.386 | -0.1944 | Yes |
| 169 | Glo1 | 18034 | -0.397 | -0.1886 | Yes |
| 170 | Apex1 | 18078 | -0.403 | -0.1803 | Yes |
| 171 | Ppm1g | 18083 | -0.403 | -0.1699 | Yes |
| 172 | Rps2 | 18142 | -0.410 | -0.1621 | Yes |
| 173 | Ilf2 | 18193 | -0.417 | -0.1537 | Yes |
| 174 | Rack1 | 18422 | -0.450 | -0.1536 | Yes |
| 175 | Snrpb2 | 18448 | -0.455 | -0.1429 | Yes |
| 176 | Got2 | 18464 | -0.456 | -0.1317 | Yes |
| 177 | Cox5a | 18506 | -0.463 | -0.1216 | Yes |
| 178 | Cdc20 | 18530 | -0.467 | -0.1105 | Yes |
| 179 | Psma1 | 18702 | -0.495 | -0.1063 | Yes |
| 180 | Vbp1 | 18722 | -0.499 | -0.0942 | Yes |
| 181 | Snrpg | 18778 | -0.509 | -0.0836 | Yes |
| 182 | Hspe1 | 18852 | -0.520 | -0.0737 | Yes |
| 183 | Ap3s1 | 18899 | -0.529 | -0.0621 | Yes |
| 184 | Rrp9 | 18959 | -0.544 | -0.0509 | Yes |
| 185 | Rps3 | 19051 | -0.574 | -0.0405 | Yes |
| 186 | Rps10 | 19129 | -0.602 | -0.0286 | Yes |
| 187 | Rpl18 | 19435 | -0.815 | -0.0229 | Yes |
| 188 | Cyc1 | 19492 | -1.021 | 0.0010 | Yes |

