Details for gene set HALLMARK_IL6_JAK_STAT3

Table: GSEA Results Summary

Dataset	MPP.MPP_Pheno.cls#Group6_versus_Group8.MPP_Pheno.cls#Group6_versus_Group8_repos
Phenotype	MPP_Pheno.cls#Group6_versus_Group8_repos
Upregulated in class	5
GeneSet	HALLMARK_IL6_JAK_STAT3_SIGNALING
Enrichment Score (ES)	-0.2396311
Normalized Enrichment Score (NES)	-0.9523577
Nominal p-value	0.53815264
FDR q-value	0.733179
FWER p-Value	0.997

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Cxcl10	1227	0.464	-0.0329	No
2	Ebi3	1535	0.435	-0.0204	No
3	Ptpn2	2245	0.372	-0.0326	No
4	Ltb	2281	0.368	-0.0104	No
5	Acvrl1	2428	0.353	0.0050	No
6	Map3k8	2528	0.345	0.0224	No
7	Tnfrsf12a	2887	0.313	0.0244	No
8	Tnf	2908	0.312	0.0436	No
9	Il12rb1	3142	0.296	0.0509	No
10	Pik3r5	3157	0.295	0.0694	No
11	Ccr1	3874	0.257	0.0493	No
12	Cd36	3902	0.255	0.0646	No
13	Ptpn11	4320	0.243	0.0589	No
14	Il9r	4429	0.236	0.0687	No
15	Il18r1	4576	0.232	0.0763	No
16	Lepr	5013	0.206	0.0674	No
17	Csf1	5240	0.193	0.0683	No
18	Jun	5804	0.164	0.0501	No
19	Il1r2	6261	0.143	0.0359	No
20	Tlr2	6668	0.123	0.0231	No
21	Il7	6875	0.115	0.0200	No
22	Cbl	7005	0.110	0.0205	No
23	Tnfrsf1b	7108	0.105	0.0221	No
24	Stat1	7223	0.100	0.0227	No
25	Il6st	7374	0.093	0.0211	No
26	Hax1	7400	0.092	0.0258	No
27	Il4ra	7444	0.090	0.0295	No
28	Il15ra	7841	0.075	0.0140	No
29	Tnfrsf21	7871	0.074	0.0173	No
30	Cd38	8125	0.064	0.0085	No
31	Itgb3	8184	0.061	0.0095	No
32	Ifnar1	8198	0.061	0.0128	No
33	Cd9	8318	0.057	0.0103	No
34	Pdgfc	8454	0.052	0.0068	No
35	Fas	8752	0.041	-0.0058	No
36	Socs1	9428	0.015	-0.0395	No
37	Cd44	10970	-0.027	-0.1170	No
38	Ltbr	10973	-0.027	-0.1154	No
39	Tnfrsf1a	11353	-0.041	-0.1322	No
40	Tyk2	11501	-0.046	-0.1367	No
41	Ptpn1	12066	-0.069	-0.1613	No
42	Csf3r	12501	-0.084	-0.1781	No
43	Il3ra	12697	-0.091	-0.1822	No
44	Irf1	13306	-0.116	-0.2060	No
45	Il1r1	13407	-0.120	-0.2033	No
46	Grb2	13566	-0.127	-0.2032	No
47	Pf4	13920	-0.142	-0.2121	No
48	Crlf2	14148	-0.153	-0.2138	No
49	Il2rg	14152	-0.153	-0.2040	No
50	Tgfb1	14198	-0.155	-0.1962	No
51	Il10rb	14475	-0.169	-0.1994	No
52	Stat2	15178	-0.205	-0.2221	No
53	Osmr	15519	-0.223	-0.2251	Yes
54	Il17ra	15616	-0.228	-0.2152	Yes
55	Stat3	15845	-0.241	-0.2112	Yes
56	Pim1	15861	-0.242	-0.1961	Yes
57	Csf2ra	15899	-0.245	-0.1821	Yes
58	Itga4	16209	-0.264	-0.1807	Yes
59	Myd88	16752	-0.296	-0.1893	Yes
60	Il13ra1	16789	-0.299	-0.1717	Yes
61	Acvr1b	17373	-0.332	-0.1801	Yes
62	Stam2	17576	-0.352	-0.1675	Yes
63	Bak1	18021	-0.395	-0.1646	Yes
64	Il17rb	18067	-0.401	-0.1408	Yes
65	Dntt	18310	-0.433	-0.1251	Yes
66	Ifngr1	18316	-0.433	-0.0971	Yes
67	Hmox1	18451	-0.455	-0.0743	Yes
68	Irf9	19056	-0.577	-0.0678	Yes
69	Socs3	19281	-0.685	-0.0347	Yes
70	Ifngr2	19334	-0.715	0.0092	Yes