| Dataset | MPP.MPP_Pheno.cls#Group6_versus_Group8.MPP_Pheno.cls#Group6_versus_Group8_repos |
| Phenotype | MPP_Pheno.cls#Group6_versus_Group8_repos |
| Upregulated in class | 5 |
| GeneSet | HALLMARK_ALLOGRAFT_REJECTION |
| Enrichment Score (ES) | -0.2783603 |
| Normalized Enrichment Score (NES) | -1.3149964 |
| Nominal p-value | 0.03258656 |
| FDR q-value | 0.3586793 |
| FWER p-Value | 0.8 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Apbb1 | 35 | 1.046 | 0.0303 | No |
| 2 | Cd247 | 189 | 0.771 | 0.0462 | No |
| 3 | Il27ra | 255 | 0.720 | 0.0649 | No |
| 4 | Lck | 777 | 0.558 | 0.0552 | No |
| 5 | Cd79a | 925 | 0.516 | 0.0635 | No |
| 6 | Stab1 | 1516 | 0.435 | 0.0464 | No |
| 7 | Hdac9 | 2238 | 0.372 | 0.0206 | No |
| 8 | Ltb | 2281 | 0.368 | 0.0297 | No |
| 9 | Degs1 | 2530 | 0.344 | 0.0275 | No |
| 10 | Prkcb | 2714 | 0.326 | 0.0281 | No |
| 11 | Ctss | 2723 | 0.325 | 0.0377 | No |
| 12 | Tpd52 | 2755 | 0.323 | 0.0460 | No |
| 13 | Tnf | 2908 | 0.312 | 0.0477 | No |
| 14 | Flna | 3002 | 0.305 | 0.0523 | No |
| 15 | Cd80 | 3131 | 0.297 | 0.0548 | No |
| 16 | Il12rb1 | 3142 | 0.296 | 0.0634 | No |
| 17 | Abi1 | 3343 | 0.286 | 0.0619 | No |
| 18 | Cd1d2 | 3414 | 0.280 | 0.0668 | No |
| 19 | Lif | 3456 | 0.277 | 0.0733 | No |
| 20 | Cd40 | 3704 | 0.264 | 0.0686 | No |
| 21 | Cxcr3 | 3720 | 0.264 | 0.0759 | No |
| 22 | Ccr1 | 3874 | 0.257 | 0.0759 | No |
| 23 | Cd74 | 4409 | 0.237 | 0.0557 | No |
| 24 | Tlr1 | 4443 | 0.236 | 0.0612 | No |
| 25 | Ly86 | 4537 | 0.235 | 0.0636 | No |
| 26 | Dyrk3 | 4595 | 0.231 | 0.0678 | No |
| 27 | Csf1 | 5240 | 0.193 | 0.0405 | No |
| 28 | Eif3d | 5946 | 0.159 | 0.0090 | No |
| 29 | Il18rap | 6106 | 0.150 | 0.0054 | No |
| 30 | Ccr5 | 6184 | 0.146 | 0.0059 | No |
| 31 | Ccr2 | 6193 | 0.146 | 0.0100 | No |
| 32 | Cd86 | 6257 | 0.143 | 0.0111 | No |
| 33 | Ncf4 | 6447 | 0.134 | 0.0055 | No |
| 34 | Tlr2 | 6668 | 0.123 | -0.0021 | No |
| 35 | Ly75 | 6738 | 0.121 | -0.0019 | No |
| 36 | Il18 | 6871 | 0.115 | -0.0052 | No |
| 37 | Il7 | 6875 | 0.115 | -0.0018 | No |
| 38 | Brca1 | 6998 | 0.110 | -0.0047 | No |
| 39 | Stat1 | 7223 | 0.100 | -0.0133 | No |
| 40 | Cfp | 7334 | 0.095 | -0.0160 | No |
| 41 | Il4ra | 7444 | 0.090 | -0.0189 | No |
| 42 | Ccnd3 | 7503 | 0.088 | -0.0192 | No |
| 43 | Bcl3 | 7506 | 0.088 | -0.0166 | No |
| 44 | Eif3a | 8024 | 0.068 | -0.0412 | No |
| 45 | Cd96 | 8041 | 0.067 | -0.0399 | No |
| 46 | Map4k1 | 8107 | 0.065 | -0.0413 | No |
| 47 | Cd4 | 8382 | 0.055 | -0.0538 | No |
| 48 | Il4 | 8466 | 0.052 | -0.0565 | No |
| 49 | Eif4g3 | 8502 | 0.050 | -0.0567 | No |
| 50 | Fas | 8752 | 0.041 | -0.0683 | No |
| 51 | Fgr | 8827 | 0.038 | -0.0710 | No |
| 52 | Socs5 | 8897 | 0.035 | -0.0735 | No |
| 53 | Lcp2 | 8982 | 0.032 | -0.0768 | No |
| 54 | Tgfb2 | 9017 | 0.030 | -0.0776 | No |
| 55 | Stat4 | 9281 | 0.020 | -0.0906 | No |
| 56 | Ache | 9333 | 0.019 | -0.0927 | No |
| 57 | Ube2n | 9423 | 0.015 | -0.0968 | No |
| 58 | Socs1 | 9428 | 0.015 | -0.0965 | No |
| 59 | Nlrp3 | 9438 | 0.015 | -0.0965 | No |
| 60 | Acvr2a | 9496 | 0.013 | -0.0991 | No |
| 61 | Ptpn6 | 9538 | 0.011 | -0.1009 | No |
| 62 | Itk | 9751 | 0.003 | -0.1117 | No |
| 63 | Elane | 10204 | -0.001 | -0.1351 | No |
| 64 | C2 | 10221 | -0.002 | -0.1358 | No |
| 65 | Icosl | 10516 | -0.011 | -0.1507 | No |
| 66 | Eif5a | 10712 | -0.016 | -0.1603 | No |
| 67 | Ccnd2 | 10731 | -0.017 | -0.1607 | No |
| 68 | Hif1a | 10764 | -0.018 | -0.1618 | No |
| 69 | H2-Oa | 10866 | -0.022 | -0.1663 | No |
| 70 | Tap2 | 11012 | -0.028 | -0.1729 | No |
| 71 | Eif3j1 | 11129 | -0.033 | -0.1779 | No |
| 72 | H2-DMa | 11513 | -0.047 | -0.1962 | No |
| 73 | Galnt1 | 11563 | -0.048 | -0.1973 | No |
| 74 | Wars1 | 11570 | -0.048 | -0.1961 | No |
| 75 | Jak2 | 11621 | -0.050 | -0.1971 | No |
| 76 | Elf4 | 11937 | -0.063 | -0.2115 | No |
| 77 | Zap70 | 12107 | -0.070 | -0.2180 | No |
| 78 | Il12a | 12173 | -0.073 | -0.2191 | No |
| 79 | F2r | 12212 | -0.075 | -0.2188 | No |
| 80 | Tlr3 | 12309 | -0.077 | -0.2214 | No |
| 81 | Icam1 | 12387 | -0.079 | -0.2229 | No |
| 82 | Glmn | 12477 | -0.083 | -0.2250 | No |
| 83 | Bcat1 | 12549 | -0.085 | -0.2260 | No |
| 84 | Cd47 | 12590 | -0.087 | -0.2254 | No |
| 85 | Ikbkb | 12689 | -0.091 | -0.2277 | No |
| 86 | Psmb10 | 12878 | -0.099 | -0.2343 | No |
| 87 | Igsf6 | 13218 | -0.111 | -0.2484 | No |
| 88 | Srgn | 13615 | -0.129 | -0.2649 | No |
| 89 | Tlr6 | 13632 | -0.130 | -0.2617 | No |
| 90 | Itgb2 | 13728 | -0.134 | -0.2625 | No |
| 91 | Fcgr2b | 13738 | -0.135 | -0.2588 | No |
| 92 | Itgal | 13750 | -0.135 | -0.2552 | No |
| 93 | Pf4 | 13920 | -0.142 | -0.2596 | No |
| 94 | Csk | 14066 | -0.148 | -0.2625 | No |
| 95 | Il2rg | 14152 | -0.153 | -0.2622 | No |
| 96 | Lyn | 14155 | -0.153 | -0.2576 | No |
| 97 | Tgfb1 | 14198 | -0.155 | -0.2550 | No |
| 98 | Hcls1 | 14236 | -0.157 | -0.2521 | No |
| 99 | Gcnt1 | 14259 | -0.158 | -0.2483 | No |
| 100 | Il2 | 14283 | -0.159 | -0.2446 | No |
| 101 | Was | 14407 | -0.165 | -0.2459 | No |
| 102 | Ptprc | 14441 | -0.167 | -0.2425 | No |
| 103 | Nck1 | 14510 | -0.170 | -0.2407 | No |
| 104 | Map3k7 | 14617 | -0.175 | -0.2409 | No |
| 105 | Mrpl3 | 14680 | -0.177 | -0.2386 | No |
| 106 | Il15 | 15451 | -0.219 | -0.2716 | Yes |
| 107 | Tapbp | 15473 | -0.220 | -0.2659 | Yes |
| 108 | Nme1 | 15702 | -0.233 | -0.2705 | Yes |
| 109 | Npm1 | 15830 | -0.240 | -0.2697 | Yes |
| 110 | Akt1 | 15850 | -0.242 | -0.2632 | Yes |
| 111 | Mtif2 | 15949 | -0.248 | -0.2607 | Yes |
| 112 | Gpr65 | 15983 | -0.250 | -0.2547 | Yes |
| 113 | Abce1 | 16005 | -0.251 | -0.2481 | Yes |
| 114 | H2-Aa | 16056 | -0.255 | -0.2428 | Yes |
| 115 | Cdkn2a | 16133 | -0.260 | -0.2388 | Yes |
| 116 | Ripk2 | 16236 | -0.266 | -0.2359 | Yes |
| 117 | Traf2 | 16247 | -0.267 | -0.2282 | Yes |
| 118 | Rpl3l | 16269 | -0.269 | -0.2210 | Yes |
| 119 | Ube2d1 | 16608 | -0.287 | -0.2296 | Yes |
| 120 | St8sia4 | 16610 | -0.287 | -0.2209 | Yes |
| 121 | Il10 | 16738 | -0.295 | -0.2183 | Yes |
| 122 | Prkcg | 16777 | -0.298 | -0.2111 | Yes |
| 123 | Cd28 | 16792 | -0.299 | -0.2027 | Yes |
| 124 | Ccl5 | 16891 | -0.303 | -0.1984 | Yes |
| 125 | Trat1 | 17174 | -0.321 | -0.2031 | Yes |
| 126 | Crtam | 17578 | -0.353 | -0.2131 | Yes |
| 127 | Capg | 17678 | -0.359 | -0.2071 | Yes |
| 128 | Rps3a1 | 17765 | -0.366 | -0.2003 | Yes |
| 129 | Rpl9 | 17796 | -0.369 | -0.1905 | Yes |
| 130 | Tap1 | 17939 | -0.385 | -0.1860 | Yes |
| 131 | Il11 | 18113 | -0.406 | -0.1824 | Yes |
| 132 | B2m | 18136 | -0.409 | -0.1710 | Yes |
| 133 | H2-Ob | 18234 | -0.422 | -0.1630 | Yes |
| 134 | Bcl10 | 18237 | -0.423 | -0.1501 | Yes |
| 135 | Irf4 | 18291 | -0.430 | -0.1396 | Yes |
| 136 | Ifngr1 | 18316 | -0.433 | -0.1275 | Yes |
| 137 | Ifnar2 | 18410 | -0.448 | -0.1185 | Yes |
| 138 | Irf7 | 18612 | -0.478 | -0.1142 | Yes |
| 139 | Spi1 | 18856 | -0.522 | -0.1107 | Yes |
| 140 | Thy1 | 19126 | -0.601 | -0.1061 | Yes |
| 141 | Irf8 | 19143 | -0.609 | -0.0882 | Yes |
| 142 | Il16 | 19223 | -0.649 | -0.0723 | Yes |
| 143 | H2-DMb2 | 19257 | -0.671 | -0.0534 | Yes |
| 144 | Rps9 | 19274 | -0.682 | -0.0333 | Yes |
| 145 | Ifngr2 | 19334 | -0.715 | -0.0143 | Yes |
| 146 | Ets1 | 19391 | -0.764 | 0.0062 | Yes |

