| Dataset | MPP.MPP_Pheno.cls#Group3_versus_Group4.MPP_Pheno.cls#Group3_versus_Group4_repos |
| Phenotype | MPP_Pheno.cls#Group3_versus_Group4_repos |
| Upregulated in class | 3 |
| GeneSet | HALLMARK_OXIDATIVE_PHOSPHORYLATION |
| Enrichment Score (ES) | -0.22761613 |
| Normalized Enrichment Score (NES) | -0.81929404 |
| Nominal p-value | 0.60308284 |
| FDR q-value | 0.91810894 |
| FWER p-Value | 1.0 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Alas1 | 1106 | 0.468 | -0.0424 | No |
| 2 | Mrpl35 | 1180 | 0.456 | -0.0317 | No |
| 3 | Retsat | 1547 | 0.410 | -0.0377 | No |
| 4 | Mrps22 | 1823 | 0.380 | -0.0399 | No |
| 5 | Atp6v1g1 | 1932 | 0.369 | -0.0337 | No |
| 6 | Mrps12 | 1962 | 0.366 | -0.0236 | No |
| 7 | Slc25a20 | 2219 | 0.347 | -0.0259 | No |
| 8 | Acadsb | 2545 | 0.321 | -0.0325 | No |
| 9 | Ndufa7 | 2787 | 0.301 | -0.0354 | No |
| 10 | Atp6v0c | 2797 | 0.301 | -0.0264 | No |
| 11 | Ndufs4 | 3062 | 0.282 | -0.0311 | No |
| 12 | Cyc1 | 3239 | 0.272 | -0.0316 | No |
| 13 | Nqo2 | 3316 | 0.267 | -0.0271 | No |
| 14 | Pdp1 | 3477 | 0.259 | -0.0272 | No |
| 15 | Mrps30 | 3500 | 0.258 | -0.0201 | No |
| 16 | Gpx4 | 3587 | 0.253 | -0.0165 | No |
| 17 | Uqcrq | 3706 | 0.246 | -0.0148 | No |
| 18 | Ndufs7 | 3784 | 0.241 | -0.0112 | No |
| 19 | Pmpca | 3830 | 0.239 | -0.0060 | No |
| 20 | Uqcrc1 | 3845 | 0.238 | 0.0009 | No |
| 21 | Hccs | 3925 | 0.233 | 0.0041 | No |
| 22 | Timm50 | 4066 | 0.225 | 0.0040 | No |
| 23 | Cox10 | 4167 | 0.221 | 0.0058 | No |
| 24 | Maob | 4259 | 0.217 | 0.0080 | No |
| 25 | Vdac1 | 4405 | 0.209 | 0.0071 | No |
| 26 | Ndufb7 | 4530 | 0.202 | 0.0071 | No |
| 27 | Cox7c | 4540 | 0.202 | 0.0131 | No |
| 28 | Mrpl11 | 4692 | 0.194 | 0.0114 | No |
| 29 | Abcb7 | 4788 | 0.188 | 0.0124 | No |
| 30 | Atp6v1c1 | 4853 | 0.184 | 0.0150 | No |
| 31 | Cyb5a | 4863 | 0.184 | 0.0203 | No |
| 32 | Vdac2 | 4911 | 0.182 | 0.0237 | No |
| 33 | Cox7a2l | 5126 | 0.171 | 0.0180 | No |
| 34 | Idh1 | 5151 | 0.170 | 0.0222 | No |
| 35 | Ldhb | 5245 | 0.165 | 0.0226 | No |
| 36 | Mrps11 | 5386 | 0.159 | 0.0204 | No |
| 37 | Fh1 | 5600 | 0.150 | 0.0141 | No |
| 38 | Cox6b1 | 5746 | 0.147 | 0.0113 | No |
| 39 | Acaa2 | 5882 | 0.140 | 0.0087 | No |
| 40 | Dlst | 6044 | 0.133 | 0.0046 | No |
| 41 | Ndufa8 | 6068 | 0.132 | 0.0076 | No |
| 42 | Cs | 6087 | 0.131 | 0.0108 | No |
| 43 | Ndufs2 | 6142 | 0.129 | 0.0121 | No |
| 44 | Mdh1 | 6425 | 0.117 | 0.0012 | No |
| 45 | Ogdh | 6457 | 0.115 | 0.0033 | No |
| 46 | Aldh6a1 | 6536 | 0.112 | 0.0028 | No |
| 47 | Mrps15 | 6590 | 0.110 | 0.0035 | No |
| 48 | Got2 | 6749 | 0.103 | -0.0014 | No |
| 49 | Ndufab1 | 6761 | 0.103 | 0.0013 | No |
| 50 | Idh3g | 6813 | 0.101 | 0.0018 | No |
| 51 | Mpc1 | 7044 | 0.092 | -0.0071 | No |
| 52 | Mtrr | 7123 | 0.089 | -0.0083 | No |
| 53 | Decr1 | 7150 | 0.088 | -0.0069 | No |
| 54 | Cox7a2 | 7296 | 0.083 | -0.0118 | No |
| 55 | Pdha1 | 7446 | 0.078 | -0.0170 | No |
| 56 | Sdhb | 7532 | 0.075 | -0.0190 | No |
| 57 | Idh2 | 7605 | 0.073 | -0.0205 | No |
| 58 | Sdhc | 7714 | 0.069 | -0.0239 | No |
| 59 | Idh3a | 7787 | 0.066 | -0.0255 | No |
| 60 | Cox17 | 8070 | 0.056 | -0.0383 | No |
| 61 | Htra2 | 8071 | 0.056 | -0.0365 | No |
| 62 | Fxn | 8083 | 0.055 | -0.0353 | No |
| 63 | Rhot2 | 8213 | 0.051 | -0.0404 | No |
| 64 | Cox15 | 8273 | 0.049 | -0.0419 | No |
| 65 | Vdac3 | 8374 | 0.045 | -0.0457 | No |
| 66 | Bax | 8461 | 0.041 | -0.0488 | No |
| 67 | Uqcrb | 8638 | 0.035 | -0.0568 | No |
| 68 | Iscu | 8720 | 0.032 | -0.0600 | No |
| 69 | Immt | 8843 | 0.027 | -0.0655 | No |
| 70 | Lrpprc | 8854 | 0.027 | -0.0651 | No |
| 71 | Fdx1 | 8965 | 0.023 | -0.0701 | No |
| 72 | Cox5a | 8972 | 0.023 | -0.0697 | No |
| 73 | Dlat | 9158 | 0.017 | -0.0787 | No |
| 74 | Acat1 | 9179 | 0.016 | -0.0792 | No |
| 75 | Mgst3 | 9186 | 0.016 | -0.0790 | No |
| 76 | Timm8b | 9333 | 0.010 | -0.0863 | No |
| 77 | Aco2 | 9453 | 0.007 | -0.0922 | No |
| 78 | Mtrf1 | 9477 | 0.007 | -0.0932 | No |
| 79 | Hadhb | 9534 | 0.005 | -0.0959 | No |
| 80 | Afg3l2 | 9582 | 0.003 | -0.0982 | No |
| 81 | Tomm22 | 9663 | 0.001 | -0.1023 | No |
| 82 | Slc25a3 | 9774 | -0.001 | -0.1080 | No |
| 83 | Timm9 | 9786 | -0.001 | -0.1086 | No |
| 84 | Opa1 | 9857 | -0.003 | -0.1121 | No |
| 85 | Acaa1a | 9987 | -0.008 | -0.1185 | No |
| 86 | Tcirg1 | 10048 | -0.010 | -0.1213 | No |
| 87 | Acadm | 10058 | -0.010 | -0.1215 | No |
| 88 | Por | 10091 | -0.011 | -0.1228 | No |
| 89 | Cox11 | 10232 | -0.016 | -0.1295 | No |
| 90 | Slc25a4 | 10396 | -0.022 | -0.1372 | No |
| 91 | Sucla2 | 10433 | -0.023 | -0.1384 | No |
| 92 | Timm13 | 10836 | -0.038 | -0.1580 | No |
| 93 | Nnt | 10916 | -0.041 | -0.1607 | No |
| 94 | Sdha | 11044 | -0.045 | -0.1659 | No |
| 95 | Slc25a12 | 11089 | -0.047 | -0.1667 | No |
| 96 | Echs1 | 11198 | -0.051 | -0.1707 | No |
| 97 | Dld | 11562 | -0.063 | -0.1874 | No |
| 98 | Phb2 | 11811 | -0.070 | -0.1980 | No |
| 99 | Atp6v1d | 11812 | -0.070 | -0.1958 | No |
| 100 | Polr2f | 11878 | -0.072 | -0.1969 | No |
| 101 | Aifm1 | 11992 | -0.076 | -0.2004 | No |
| 102 | Hspa9 | 12083 | -0.079 | -0.2025 | No |
| 103 | Gpi1 | 12106 | -0.080 | -0.2011 | No |
| 104 | Cox5b | 12176 | -0.082 | -0.2021 | No |
| 105 | Idh3b | 12368 | -0.089 | -0.2091 | No |
| 106 | Mrpl15 | 12528 | -0.094 | -0.2144 | No |
| 107 | Uqcr11 | 12549 | -0.095 | -0.2124 | No |
| 108 | Ndufv1 | 12556 | -0.095 | -0.2097 | No |
| 109 | Acadvl | 12653 | -0.098 | -0.2116 | No |
| 110 | Ndufs1 | 12664 | -0.099 | -0.2090 | No |
| 111 | Atp1b1 | 12758 | -0.102 | -0.2105 | No |
| 112 | Hadha | 12841 | -0.105 | -0.2115 | No |
| 113 | Ndufb2 | 12881 | -0.106 | -0.2101 | No |
| 114 | Ndufa1 | 12924 | -0.108 | -0.2089 | No |
| 115 | Uqcrh | 12935 | -0.109 | -0.2059 | No |
| 116 | Cox6c | 13089 | -0.115 | -0.2102 | No |
| 117 | Ndufs8 | 13111 | -0.116 | -0.2076 | No |
| 118 | Tomm70a | 13460 | -0.129 | -0.2215 | No |
| 119 | Ndufb3 | 13579 | -0.134 | -0.2234 | Yes |
| 120 | Cox6a1 | 13593 | -0.134 | -0.2198 | Yes |
| 121 | Pdhx | 13622 | -0.135 | -0.2169 | Yes |
| 122 | Slc25a11 | 13787 | -0.142 | -0.2209 | Yes |
| 123 | Atp6v1h | 13848 | -0.143 | -0.2195 | Yes |
| 124 | Glud1 | 13872 | -0.144 | -0.2161 | Yes |
| 125 | Ech1 | 13902 | -0.145 | -0.2130 | Yes |
| 126 | Rhot1 | 13949 | -0.147 | -0.2108 | Yes |
| 127 | Oxa1l | 14139 | -0.154 | -0.2157 | Yes |
| 128 | Uqcr10 | 14158 | -0.155 | -0.2117 | Yes |
| 129 | Grpel1 | 14216 | -0.157 | -0.2097 | Yes |
| 130 | Cox8a | 14224 | -0.157 | -0.2051 | Yes |
| 131 | Eci1 | 14422 | -0.165 | -0.2100 | Yes |
| 132 | Etfa | 14424 | -0.165 | -0.2048 | Yes |
| 133 | Oat | 14458 | -0.167 | -0.2012 | Yes |
| 134 | Ndufv2 | 14493 | -0.169 | -0.1976 | Yes |
| 135 | Atp6ap1 | 14568 | -0.172 | -0.1960 | Yes |
| 136 | Atp5pb | 14611 | -0.174 | -0.1927 | Yes |
| 137 | Casp7 | 14647 | -0.175 | -0.1890 | Yes |
| 138 | Pdk4 | 14716 | -0.178 | -0.1868 | Yes |
| 139 | Etfb | 14729 | -0.179 | -0.1818 | Yes |
| 140 | Ndufa4 | 14750 | -0.179 | -0.1771 | Yes |
| 141 | Mtx2 | 14906 | -0.184 | -0.1793 | Yes |
| 142 | Mdh2 | 14988 | -0.187 | -0.1776 | Yes |
| 143 | Timm10 | 14990 | -0.187 | -0.1717 | Yes |
| 144 | Supv3l1 | 15155 | -0.194 | -0.1740 | Yes |
| 145 | Ndufc1 | 15228 | -0.198 | -0.1715 | Yes |
| 146 | Ndufa3 | 15253 | -0.200 | -0.1664 | Yes |
| 147 | Atp6v0e | 15380 | -0.206 | -0.1664 | Yes |
| 148 | Slc25a5 | 15697 | -0.222 | -0.1757 | Yes |
| 149 | Ndufc2 | 16013 | -0.239 | -0.1844 | Yes |
| 150 | Etfdh | 16089 | -0.243 | -0.1806 | Yes |
| 151 | Ndufa5 | 16164 | -0.248 | -0.1766 | Yes |
| 152 | Atp6v1f | 16323 | -0.256 | -0.1766 | Yes |
| 153 | Ndufs3 | 16533 | -0.270 | -0.1789 | Yes |
| 154 | Uqcrc2 | 16569 | -0.271 | -0.1721 | Yes |
| 155 | Cox4i1 | 16872 | -0.292 | -0.1785 | Yes |
| 156 | Ndufa9 | 16910 | -0.294 | -0.1711 | Yes |
| 157 | Ndufa2 | 16942 | -0.295 | -0.1633 | Yes |
| 158 | Suclg1 | 16951 | -0.296 | -0.1544 | Yes |
| 159 | Pdhb | 17220 | -0.313 | -0.1583 | Yes |
| 160 | Bckdha | 17289 | -0.318 | -0.1518 | Yes |
| 161 | Atp6v0b | 17417 | -0.327 | -0.1480 | Yes |
| 162 | Atp6v1e1 | 17423 | -0.328 | -0.1378 | Yes |
| 163 | Mrpl34 | 17446 | -0.329 | -0.1285 | Yes |
| 164 | Ndufs6 | 17518 | -0.337 | -0.1215 | Yes |
| 165 | Ndufb6 | 17543 | -0.341 | -0.1120 | Yes |
| 166 | Sdhd | 17638 | -0.351 | -0.1057 | Yes |
| 167 | Ndufa6 | 17642 | -0.352 | -0.0947 | Yes |
| 168 | Timm17a | 17714 | -0.356 | -0.0871 | Yes |
| 169 | Phyh | 17788 | -0.364 | -0.0794 | Yes |
| 170 | Ldha | 17839 | -0.370 | -0.0702 | Yes |
| 171 | Hsd17b10 | 17937 | -0.379 | -0.0632 | Yes |
| 172 | Uqcrfs1 | 18017 | -0.388 | -0.0550 | Yes |
| 173 | Surf1 | 18059 | -0.391 | -0.0447 | Yes |
| 174 | Ndufb8 | 18314 | -0.418 | -0.0447 | Yes |
| 175 | Mfn2 | 18380 | -0.426 | -0.0345 | Yes |
| 176 | Prdx3 | 18469 | -0.437 | -0.0252 | Yes |
| 177 | Cox7b | 18581 | -0.452 | -0.0166 | Yes |
| 178 | Cpt1a | 18614 | -0.457 | -0.0038 | Yes |
| 179 | Ndufb5 | 18711 | -0.473 | 0.0062 | Yes |
| 180 | Bdh2 | 18877 | -0.507 | 0.0137 | Yes |
| 181 | Cyb5r3 | 19201 | -0.602 | 0.0161 | Yes |

