| Dataset | MPP.MPP_Pheno.cls#Group3_versus_Group4.MPP_Pheno.cls#Group3_versus_Group4_repos |
| Phenotype | MPP_Pheno.cls#Group3_versus_Group4_repos |
| Upregulated in class | 2 |
| GeneSet | HALLMARK_GLYCOLYSIS |
| Enrichment Score (ES) | 0.20050986 |
| Normalized Enrichment Score (NES) | 0.9668252 |
| Nominal p-value | 0.561753 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Stc2 | 25 | 1.071 | 0.0248 | Yes |
| 2 | Adora2b | 70 | 0.910 | 0.0447 | Yes |
| 3 | Pcx | 309 | 0.686 | 0.0491 | Yes |
| 4 | Cenpa | 313 | 0.686 | 0.0657 | Yes |
| 5 | Stmn1 | 326 | 0.679 | 0.0816 | Yes |
| 6 | Dcn | 377 | 0.652 | 0.0949 | Yes |
| 7 | Ndst3 | 430 | 0.627 | 0.1075 | Yes |
| 8 | Hmmr | 439 | 0.624 | 0.1223 | Yes |
| 9 | Dsc2 | 514 | 0.604 | 0.1331 | Yes |
| 10 | B4galt4 | 547 | 0.591 | 0.1459 | Yes |
| 11 | Tpbg | 861 | 0.511 | 0.1421 | Yes |
| 12 | Depdc1a | 937 | 0.499 | 0.1504 | Yes |
| 13 | Me2 | 1057 | 0.475 | 0.1558 | Yes |
| 14 | Hk2 | 1466 | 0.420 | 0.1450 | Yes |
| 15 | Il13ra1 | 1487 | 0.417 | 0.1541 | Yes |
| 16 | Gpc1 | 1545 | 0.410 | 0.1612 | Yes |
| 17 | Ppfia4 | 1594 | 0.404 | 0.1685 | Yes |
| 18 | Cdk1 | 1624 | 0.401 | 0.1768 | Yes |
| 19 | Ak4 | 1704 | 0.392 | 0.1823 | Yes |
| 20 | Srd5a3 | 1710 | 0.391 | 0.1915 | Yes |
| 21 | Egln3 | 1875 | 0.375 | 0.1922 | Yes |
| 22 | Gpr87 | 2047 | 0.359 | 0.1921 | Yes |
| 23 | Xylt2 | 2303 | 0.338 | 0.1871 | Yes |
| 24 | Ppp2cb | 2351 | 0.333 | 0.1928 | Yes |
| 25 | Slc37a4 | 2360 | 0.332 | 0.2005 | Yes |
| 26 | Pkp2 | 2615 | 0.316 | 0.1951 | No |
| 27 | Phka2 | 2921 | 0.291 | 0.1864 | No |
| 28 | B3gnt3 | 3237 | 0.272 | 0.1767 | No |
| 29 | Gpc4 | 3276 | 0.269 | 0.1813 | No |
| 30 | Lhpp | 3361 | 0.264 | 0.1834 | No |
| 31 | Eno2 | 3638 | 0.250 | 0.1752 | No |
| 32 | Homer1 | 3650 | 0.250 | 0.1807 | No |
| 33 | Chpf2 | 3754 | 0.243 | 0.1813 | No |
| 34 | Chst12 | 3755 | 0.243 | 0.1872 | No |
| 35 | Qsox1 | 3975 | 0.230 | 0.1815 | No |
| 36 | Ext2 | 3984 | 0.230 | 0.1867 | No |
| 37 | Ndufv3 | 4132 | 0.223 | 0.1845 | No |
| 38 | Agl | 4384 | 0.211 | 0.1767 | No |
| 39 | Eno1b | 4390 | 0.211 | 0.1816 | No |
| 40 | Ext1 | 4694 | 0.194 | 0.1706 | No |
| 41 | Plod2 | 4754 | 0.190 | 0.1722 | No |
| 42 | Nanp | 4801 | 0.187 | 0.1744 | No |
| 43 | Cyb5a | 4863 | 0.184 | 0.1757 | No |
| 44 | Ppia | 4924 | 0.181 | 0.1770 | No |
| 45 | Bpnt1 | 4973 | 0.179 | 0.1789 | No |
| 46 | B3galt6 | 5021 | 0.177 | 0.1808 | No |
| 47 | Kif20a | 5033 | 0.176 | 0.1845 | No |
| 48 | Cited2 | 5037 | 0.176 | 0.1886 | No |
| 49 | Gys1 | 5129 | 0.171 | 0.1881 | No |
| 50 | Idh1 | 5151 | 0.170 | 0.1911 | No |
| 51 | Agrn | 5195 | 0.168 | 0.1930 | No |
| 52 | Ier3 | 5223 | 0.166 | 0.1956 | No |
| 53 | Mpi | 5338 | 0.160 | 0.1937 | No |
| 54 | Fam162a | 5414 | 0.157 | 0.1936 | No |
| 55 | Idua | 5766 | 0.145 | 0.1790 | No |
| 56 | Slc16a3 | 5790 | 0.144 | 0.1813 | No |
| 57 | Sdc2 | 5933 | 0.137 | 0.1773 | No |
| 58 | Mdh1 | 6425 | 0.117 | 0.1548 | No |
| 59 | Tpi1 | 6456 | 0.115 | 0.1560 | No |
| 60 | Paxip1 | 6633 | 0.108 | 0.1496 | No |
| 61 | Nasp | 6657 | 0.107 | 0.1510 | No |
| 62 | Taldo1 | 6678 | 0.106 | 0.1525 | No |
| 63 | Pfkfb1 | 6680 | 0.106 | 0.1551 | No |
| 64 | Got2 | 6749 | 0.103 | 0.1541 | No |
| 65 | Rpe | 6975 | 0.095 | 0.1447 | No |
| 66 | Mif | 7133 | 0.089 | 0.1388 | No |
| 67 | Nol3 | 7182 | 0.087 | 0.1384 | No |
| 68 | Alg1 | 7216 | 0.086 | 0.1388 | No |
| 69 | Pygb | 7240 | 0.085 | 0.1397 | No |
| 70 | Hspa5 | 7267 | 0.084 | 0.1404 | No |
| 71 | Cxcr4 | 7314 | 0.082 | 0.1400 | No |
| 72 | Pgm2 | 7685 | 0.070 | 0.1226 | No |
| 73 | Sdhc | 7714 | 0.069 | 0.1228 | No |
| 74 | B4galt7 | 7729 | 0.068 | 0.1238 | No |
| 75 | Pygl | 7896 | 0.062 | 0.1167 | No |
| 76 | Fkbp4 | 8219 | 0.051 | 0.1013 | No |
| 77 | Nt5e | 8220 | 0.051 | 0.1025 | No |
| 78 | B4galt2 | 8296 | 0.047 | 0.0998 | No |
| 79 | Cd44 | 8439 | 0.042 | 0.0935 | No |
| 80 | Tgfa | 8751 | 0.031 | 0.0781 | No |
| 81 | Pfkp | 8994 | 0.023 | 0.0662 | No |
| 82 | B4galt1 | 8998 | 0.022 | 0.0666 | No |
| 83 | Angptl4 | 9090 | 0.019 | 0.0623 | No |
| 84 | Pgk1 | 9133 | 0.017 | 0.0606 | No |
| 85 | P4ha1 | 9174 | 0.016 | 0.0589 | No |
| 86 | Gne | 9452 | 0.007 | 0.0447 | No |
| 87 | Aldoa | 9527 | 0.005 | 0.0410 | No |
| 88 | Capn5 | 9668 | 0.001 | 0.0338 | No |
| 89 | Aldh7a1 | 9781 | -0.001 | 0.0280 | No |
| 90 | Sod1 | 9954 | -0.007 | 0.0193 | No |
| 91 | Pam | 10113 | -0.012 | 0.0114 | No |
| 92 | Ugp2 | 10132 | -0.013 | 0.0108 | No |
| 93 | Aurka | 10413 | -0.022 | -0.0031 | No |
| 94 | Aldh9a1 | 10735 | -0.034 | -0.0189 | No |
| 95 | Ddit4 | 10873 | -0.039 | -0.0250 | No |
| 96 | Cln6 | 10875 | -0.039 | -0.0241 | No |
| 97 | Hax1 | 10997 | -0.044 | -0.0293 | No |
| 98 | Slc25a13 | 11116 | -0.048 | -0.0342 | No |
| 99 | Polr3k | 11166 | -0.050 | -0.0356 | No |
| 100 | Rragd | 11180 | -0.050 | -0.0350 | No |
| 101 | Chst2 | 11264 | -0.053 | -0.0380 | No |
| 102 | Gale | 11317 | -0.055 | -0.0394 | No |
| 103 | Dld | 11562 | -0.063 | -0.0505 | No |
| 104 | Mxi1 | 11571 | -0.064 | -0.0493 | No |
| 105 | Cog2 | 11589 | -0.064 | -0.0487 | No |
| 106 | Hdlbp | 12024 | -0.077 | -0.0692 | No |
| 107 | Zfp292 | 12139 | -0.081 | -0.0731 | No |
| 108 | Glrx | 12391 | -0.090 | -0.0839 | No |
| 109 | Gfpt1 | 12563 | -0.095 | -0.0905 | No |
| 110 | Kif2a | 12646 | -0.098 | -0.0923 | No |
| 111 | Irs2 | 12712 | -0.100 | -0.0932 | No |
| 112 | Vldlr | 13054 | -0.114 | -0.1081 | No |
| 113 | Me1 | 13084 | -0.115 | -0.1068 | No |
| 114 | Gnpda1 | 13098 | -0.116 | -0.1046 | No |
| 115 | Vegfa | 13218 | -0.120 | -0.1079 | No |
| 116 | Ak3 | 13578 | -0.134 | -0.1232 | No |
| 117 | Rbck1 | 13623 | -0.135 | -0.1222 | No |
| 118 | Pkm | 13687 | -0.138 | -0.1220 | No |
| 119 | Bik | 13723 | -0.140 | -0.1205 | No |
| 120 | Pmm2 | 13954 | -0.147 | -0.1288 | No |
| 121 | Slc25a10 | 14048 | -0.151 | -0.1299 | No |
| 122 | Slc35a3 | 14162 | -0.155 | -0.1320 | No |
| 123 | Glce | 14466 | -0.168 | -0.1436 | No |
| 124 | Isg20 | 14763 | -0.180 | -0.1545 | No |
| 125 | Arpp19 | 14842 | -0.181 | -0.1541 | No |
| 126 | Gclc | 14863 | -0.182 | -0.1507 | No |
| 127 | Mdh2 | 14988 | -0.187 | -0.1526 | No |
| 128 | Sdc1 | 15060 | -0.190 | -0.1516 | No |
| 129 | Galk2 | 15243 | -0.199 | -0.1562 | No |
| 130 | Kdelr3 | 15245 | -0.199 | -0.1514 | No |
| 131 | Copb2 | 15318 | -0.203 | -0.1502 | No |
| 132 | Akr1a1 | 15559 | -0.215 | -0.1573 | No |
| 133 | Ero1a | 15578 | -0.216 | -0.1530 | No |
| 134 | Pdk3 | 15594 | -0.217 | -0.1485 | No |
| 135 | Met | 15721 | -0.223 | -0.1496 | No |
| 136 | Gusb | 15785 | -0.226 | -0.1473 | No |
| 137 | Gmppa | 15807 | -0.228 | -0.1429 | No |
| 138 | Psmc4 | 15871 | -0.231 | -0.1405 | No |
| 139 | B3gat3 | 15872 | -0.231 | -0.1348 | No |
| 140 | Nsdhl | 16029 | -0.240 | -0.1371 | No |
| 141 | Pgam1 | 16134 | -0.246 | -0.1364 | No |
| 142 | Ecd | 16140 | -0.247 | -0.1307 | No |
| 143 | Chpf | 16203 | -0.250 | -0.1278 | No |
| 144 | Gpc3 | 16233 | -0.251 | -0.1232 | No |
| 145 | G6pdx | 16523 | -0.270 | -0.1316 | No |
| 146 | Tpst1 | 16605 | -0.274 | -0.1291 | No |
| 147 | Got1 | 16680 | -0.279 | -0.1261 | No |
| 148 | Col5a1 | 16718 | -0.281 | -0.1212 | No |
| 149 | Hs2st1 | 16766 | -0.284 | -0.1167 | No |
| 150 | Med24 | 16788 | -0.285 | -0.1108 | No |
| 151 | Plod1 | 17095 | -0.306 | -0.1192 | No |
| 152 | Sdc3 | 17117 | -0.307 | -0.1128 | No |
| 153 | Sap30 | 17204 | -0.312 | -0.1096 | No |
| 154 | Gapdhs | 17376 | -0.325 | -0.1105 | No |
| 155 | Galk1 | 17438 | -0.329 | -0.1057 | No |
| 156 | Ankzf1 | 17603 | -0.347 | -0.1057 | No |
| 157 | Mertk | 17620 | -0.349 | -0.0980 | No |
| 158 | Lct | 17634 | -0.350 | -0.0902 | No |
| 159 | Ang | 17649 | -0.352 | -0.0823 | No |
| 160 | Hs6st2 | 17729 | -0.357 | -0.0777 | No |
| 161 | Ldha | 17839 | -0.370 | -0.0743 | No |
| 162 | Gal3st1 | 17860 | -0.371 | -0.0663 | No |
| 163 | Casp6 | 18107 | -0.396 | -0.0694 | No |
| 164 | Pgls | 18181 | -0.403 | -0.0633 | No |
| 165 | Gfus | 18265 | -0.412 | -0.0576 | No |
| 166 | Spag4 | 18275 | -0.413 | -0.0480 | No |
| 167 | Fut8 | 18373 | -0.426 | -0.0426 | No |
| 168 | Prps1 | 18479 | -0.438 | -0.0374 | No |
| 169 | Txn1 | 18563 | -0.449 | -0.0307 | No |
| 170 | P4ha2 | 18777 | -0.487 | -0.0299 | No |
| 171 | Gmppb | 18837 | -0.500 | -0.0208 | No |
| 172 | Tgfbi | 19066 | -0.552 | -0.0191 | No |
| 173 | Abcb6 | 19363 | -0.707 | -0.0172 | No |
| 174 | Vcan | 19498 | -1.021 | 0.0007 | No |

