Details for gene set HALLMARK_P53

Table: GSEA Results Summary

Dataset	MPP.MPP_Pheno.cls#Group2_versus_Group4.MPP_Pheno.cls#Group2_versus_Group4_repos
Phenotype	MPP_Pheno.cls#Group2_versus_Group4_repos
Upregulated in class	3
GeneSet	HALLMARK_P53_PATHWAY
Enrichment Score (ES)	-0.23406747
Normalized Enrichment Score (NES)	-0.98857343
Nominal p-value	0.475891
FDR q-value	1.0
FWER p-Value	1.0

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Stom	11	1.131	0.0216	No
2	Gls2	56	0.926	0.0375	No
3	Zmat3	67	0.901	0.0547	No
4	Fos	232	0.708	0.0601	No
5	Plxnb2	359	0.646	0.0662	No
6	Hexim1	415	0.622	0.0756	No
7	App	448	0.612	0.0860	No
8	Rxra	475	0.603	0.0964	No
9	Lif	483	0.601	0.1079	No
10	Ip6k2	701	0.546	0.1074	No
11	H1f2	806	0.528	0.1123	No
12	Slc35d1	847	0.523	0.1205	No
13	Jun	963	0.503	0.1245	No
14	Phlda3	1008	0.495	0.1319	No
15	Ier5	1042	0.490	0.1398	No
16	Eps8l2	1342	0.449	0.1331	No
17	Cdkn1a	1446	0.437	0.1364	No
18	Atf3	1713	0.405	0.1305	No
19	Rab40c	1953	0.381	0.1257	No
20	Acvr1b	2402	0.341	0.1092	No
21	Ak1	2469	0.336	0.1123	No
22	Cdkn2a	2493	0.334	0.1177	No
23	Csrnp2	2549	0.330	0.1213	No
24	Ccp110	2569	0.328	0.1268	No
25	Cdkn2aip	2595	0.327	0.1319	No
26	Mdm2	2640	0.323	0.1360	No
27	Rad51c	2733	0.316	0.1374	No
28	Elp1	2824	0.309	0.1388	No
29	Fdxr	2843	0.308	0.1439	No
30	Trp63	2958	0.301	0.1439	No
31	Ctsd	2987	0.300	0.1484	No
32	Plk3	3192	0.287	0.1435	No
33	Ier3	3305	0.281	0.1432	No
34	Prmt2	3310	0.280	0.1485	No
35	Blcap	3582	0.264	0.1396	No
36	Fgf13	3813	0.250	0.1327	No
37	Coq8a	4268	0.223	0.1135	No
38	Fas	4319	0.220	0.1153	No
39	Xpc	4473	0.215	0.1116	No
40	Cd82	4616	0.208	0.1083	No
41	Cdk5r1	4760	0.200	0.1048	No
42	Rad9a	4893	0.193	0.1018	No
43	Retsat	4969	0.189	0.1016	No
44	Sp1	4988	0.188	0.1044	No
45	Rhbdf2	5119	0.183	0.1012	No
46	Itgb4	5158	0.181	0.1028	No
47	Pcna	5182	0.179	0.1051	No
48	Sfn	5314	0.171	0.1017	No
49	Aen	5451	0.165	0.0979	No
50	Pmm1	5760	0.151	0.0849	No
51	S100a4	5839	0.147	0.0838	No
52	Hspa4l	5909	0.143	0.0830	No
53	Foxo3	5957	0.140	0.0833	No
54	Fuca1	6086	0.134	0.0793	No
55	Tax1bp3	6181	0.131	0.0770	No
56	Perp	6262	0.126	0.0754	No
57	Hmox1	6433	0.121	0.0689	No
58	Nupr1	6674	0.110	0.0587	No
59	Mknk2	6792	0.103	0.0547	No
60	Slc3a2	6890	0.099	0.0516	No
61	Ddit3	7017	0.093	0.0469	No
62	Sdc1	7084	0.090	0.0453	No
63	Pvt1	7161	0.087	0.0430	No
64	Baiap2	7222	0.085	0.0416	No
65	Mxd1	7251	0.084	0.0418	No
66	Apaf1	7427	0.078	0.0343	No
67	Ada	7646	0.070	0.0243	No
68	Rb1	7699	0.067	0.0230	No
69	Triap1	7834	0.062	0.0173	No
70	Dcxr	7885	0.060	0.0159	No
71	Gadd45a	7891	0.060	0.0168	No
72	Rrp8	8058	0.053	0.0092	No
73	Ptpn14	8086	0.051	0.0088	No
74	Slc7a11	8209	0.047	0.0034	No
75	Tob1	8234	0.046	0.0031	No
76	Tpd52l1	8340	0.042	-0.0015	No
77	Zfp36l1	8403	0.039	-0.0040	No
78	Ppp1r15a	8612	0.030	-0.0142	No
79	Pom121	8651	0.028	-0.0156	No
80	Ccnk	8703	0.026	-0.0177	No
81	Kif13b	8726	0.025	-0.0183	No
82	Klf4	8842	0.020	-0.0239	No
83	Nol8	8998	0.015	-0.0316	No
84	Polh	9303	0.005	-0.0473	No
85	Slc19a2	9364	0.002	-0.0503	No
86	Vwa5a	9547	-0.002	-0.0597	No
87	Tspyl2	9606	-0.005	-0.0626	No
88	Rap2b	9819	-0.013	-0.0733	No
89	Plk2	9938	-0.019	-0.0791	No
90	Pdgfa	10108	-0.024	-0.0873	No
91	Irag2	10188	-0.028	-0.0909	No
92	Mapkapk3	10632	-0.045	-0.1129	No
93	Osgin1	10819	-0.053	-0.1215	No
94	Hbegf	11173	-0.067	-0.1384	No
95	Ddb2	11259	-0.070	-0.1415	No
96	Abcc5	11441	-0.077	-0.1493	No
97	Sertad3	11448	-0.077	-0.1481	No
98	Hras	11466	-0.078	-0.1475	No
99	Pidd1	11790	-0.093	-0.1624	No
100	S100a10	11966	-0.100	-0.1695	No
101	Sat1	12161	-0.109	-0.1774	No
102	Bax	12342	-0.116	-0.1844	No
103	Fbxw7	12661	-0.127	-0.1984	No
104	Dnttip2	12850	-0.134	-0.2055	No
105	Ccng1	13103	-0.146	-0.2157	No
106	Rps27l	13122	-0.146	-0.2137	No
107	Abat	13257	-0.153	-0.2177	No
108	Ninj1	13298	-0.155	-0.2167	No
109	Txnip	13381	-0.159	-0.2178	No
110	Vdr	13421	-0.161	-0.2167	No
111	Tm7sf3	13535	-0.166	-0.2192	No
112	Iscu	13566	-0.167	-0.2175	No
113	Prkab1	13742	-0.176	-0.2231	No
114	Ccnd3	13876	-0.181	-0.2265	No
115	Zbtb16	13887	-0.181	-0.2234	No
116	Rpl36	13895	-0.182	-0.2202	No
117	Trafd1	13951	-0.185	-0.2194	No
118	H2ac25	13971	-0.185	-0.2168	No
119	Ddit4	14083	-0.191	-0.2188	No
120	Rchy1	14179	-0.195	-0.2199	No
121	Rpl18	14243	-0.199	-0.2192	No
122	Traf4	14531	-0.213	-0.2299	Yes
123	Cyfip2	14591	-0.215	-0.2287	Yes
124	Tsc22d1	14599	-0.216	-0.2248	Yes
125	Btg2	14622	-0.217	-0.2217	Yes
126	Hint1	14698	-0.221	-0.2213	Yes
127	Pitpnc1	14703	-0.221	-0.2171	Yes
128	Cgrrf1	14781	-0.224	-0.2167	Yes
129	Ei24	14786	-0.224	-0.2125	Yes
130	Rack1	14833	-0.227	-0.2105	Yes
131	Wwp1	14848	-0.228	-0.2067	Yes
132	Mxd4	14875	-0.230	-0.2035	Yes
133	Sphk1	15073	-0.240	-0.2090	Yes
134	Jag2	15080	-0.241	-0.2046	Yes
135	Fam162a	15147	-0.244	-0.2032	Yes
136	Ppm1d	15184	-0.246	-0.2003	Yes
137	Sesn1	15213	-0.248	-0.1969	Yes
138	Hdac3	15581	-0.268	-0.2106	Yes
139	Ephx1	15592	-0.268	-0.2059	Yes
140	H2aj	15702	-0.275	-0.2061	Yes
141	Ifi30	15734	-0.277	-0.2023	Yes
142	Tnfsf9	15770	-0.279	-0.1986	Yes
143	Casp1	15854	-0.285	-0.1973	Yes
144	Wrap73	15956	-0.290	-0.1969	Yes
145	Tgfa	15994	-0.292	-0.1931	Yes
146	Rnf19b	16115	-0.299	-0.1934	Yes
147	Alox8	16178	-0.301	-0.1907	Yes
148	Tgfb1	16282	-0.307	-0.1900	Yes
149	Ercc5	16287	-0.308	-0.1841	Yes
150	Gm2a	16314	-0.310	-0.1794	Yes
151	Trp53	16451	-0.318	-0.1802	Yes
152	Bak1	16530	-0.322	-0.1779	Yes
153	Sec61a1	16537	-0.322	-0.1719	Yes
154	Irak1	16625	-0.328	-0.1700	Yes
155	Abhd4	16695	-0.332	-0.1670	Yes
156	Ndrg1	16749	-0.336	-0.1632	Yes
157	Rps12	16814	-0.341	-0.1598	Yes
158	Nudt15	16823	-0.342	-0.1535	Yes
159	Klk8	16849	-0.344	-0.1481	Yes
160	Epha2	16882	-0.347	-0.1429	Yes
161	Notch1	16938	-0.351	-0.1389	Yes
162	Ptpre	17093	-0.361	-0.1398	Yes
163	Cdh13	17437	-0.387	-0.1499	Yes
164	Rrad	17456	-0.390	-0.1432	Yes
165	St14	17459	-0.390	-0.1357	Yes
166	Dram1	17465	-0.390	-0.1283	Yes
167	Tap1	17537	-0.397	-0.1241	Yes
168	Vamp8	17565	-0.399	-0.1177	Yes
169	Cd81	17592	-0.402	-0.1112	Yes
170	F2r	17793	-0.420	-0.1133	Yes
171	Def6	17986	-0.441	-0.1146	Yes
172	Ralgds	18060	-0.448	-0.1095	Yes
173	Trib3	18214	-0.466	-0.1083	Yes
174	Btg1	18274	-0.473	-0.1021	Yes
175	Socs1	18462	-0.502	-0.1019	Yes
176	Tcn2	18751	-0.550	-0.1060	Yes
177	Zfp365	18824	-0.565	-0.0987	Yes
178	Ccnd2	18993	-0.609	-0.0954	Yes
179	Ankra2	19029	-0.621	-0.0850	Yes
180	Procr	19031	-0.622	-0.0729	Yes
181	Ldhb	19087	-0.641	-0.0632	Yes
182	Steap3	19097	-0.645	-0.0510	Yes
183	Cebpa	19128	-0.660	-0.0396	Yes
184	Upp1	19252	-0.727	-0.0317	Yes
185	Dgka	19255	-0.729	-0.0175	Yes
186	Tprkb	19289	-0.751	-0.0044	Yes
187	Ctsf	19362	-0.812	0.0078	Yes