| Dataset | MPP.MPP_Pheno.cls#Group2_versus_Group4.MPP_Pheno.cls#Group2_versus_Group4_repos |
| Phenotype | MPP_Pheno.cls#Group2_versus_Group4_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_G2M_CHECKPOINT |
| Enrichment Score (ES) | 0.48002717 |
| Normalized Enrichment Score (NES) | 1.4742293 |
| Nominal p-value | 0.15913557 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.48 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Hnrnpu | 191 | 0.739 | 0.0066 | Yes |
| 2 | Mcm2 | 306 | 0.668 | 0.0155 | Yes |
| 3 | Racgap1 | 328 | 0.656 | 0.0290 | Yes |
| 4 | Hspa8 | 376 | 0.637 | 0.0408 | Yes |
| 5 | Srsf1 | 487 | 0.600 | 0.0484 | Yes |
| 6 | Fbxo5 | 490 | 0.598 | 0.0616 | Yes |
| 7 | Lmnb1 | 499 | 0.595 | 0.0745 | Yes |
| 8 | Kpnb1 | 692 | 0.548 | 0.0767 | Yes |
| 9 | Xpo1 | 700 | 0.546 | 0.0885 | Yes |
| 10 | Prmt5 | 784 | 0.533 | 0.0961 | Yes |
| 11 | Rasal2 | 803 | 0.529 | 0.1069 | Yes |
| 12 | Odc1 | 912 | 0.510 | 0.1127 | Yes |
| 13 | Cdc7 | 934 | 0.506 | 0.1228 | Yes |
| 14 | Numa1 | 940 | 0.505 | 0.1338 | Yes |
| 15 | Sqle | 1000 | 0.496 | 0.1418 | Yes |
| 16 | Mcm6 | 1017 | 0.493 | 0.1519 | Yes |
| 17 | Ndc80 | 1067 | 0.486 | 0.1602 | Yes |
| 18 | Efna5 | 1085 | 0.484 | 0.1701 | Yes |
| 19 | Nasp | 1221 | 0.463 | 0.1734 | Yes |
| 20 | Nup98 | 1331 | 0.450 | 0.1778 | Yes |
| 21 | Mcm3 | 1359 | 0.447 | 0.1863 | Yes |
| 22 | Upf1 | 1365 | 0.446 | 0.1960 | Yes |
| 23 | Cdc25a | 1496 | 0.429 | 0.1988 | Yes |
| 24 | Top2a | 1512 | 0.428 | 0.2076 | Yes |
| 25 | Bard1 | 1542 | 0.424 | 0.2155 | Yes |
| 26 | Hnrnpd | 1547 | 0.423 | 0.2247 | Yes |
| 27 | Chek1 | 1639 | 0.413 | 0.2291 | Yes |
| 28 | G3bp1 | 1642 | 0.412 | 0.2382 | Yes |
| 29 | Incenp | 1648 | 0.412 | 0.2471 | Yes |
| 30 | Kif23 | 1674 | 0.409 | 0.2549 | Yes |
| 31 | Aurkb | 1780 | 0.399 | 0.2584 | Yes |
| 32 | Dtymk | 1819 | 0.396 | 0.2652 | Yes |
| 33 | Chaf1a | 1821 | 0.395 | 0.2739 | Yes |
| 34 | Smc1a | 1823 | 0.395 | 0.2827 | Yes |
| 35 | Tacc3 | 1833 | 0.395 | 0.2910 | Yes |
| 36 | Kif2c | 1859 | 0.392 | 0.2984 | Yes |
| 37 | Tmpo | 1892 | 0.389 | 0.3054 | Yes |
| 38 | Stmn1 | 1981 | 0.379 | 0.3093 | Yes |
| 39 | Exo1 | 2005 | 0.376 | 0.3165 | Yes |
| 40 | Tfdp1 | 2280 | 0.350 | 0.3101 | Yes |
| 41 | Cul1 | 2337 | 0.345 | 0.3148 | Yes |
| 42 | Mybl2 | 2343 | 0.345 | 0.3222 | Yes |
| 43 | Nsd2 | 2363 | 0.344 | 0.3289 | Yes |
| 44 | Kif22 | 2439 | 0.337 | 0.3325 | Yes |
| 45 | Uck2 | 2506 | 0.333 | 0.3365 | Yes |
| 46 | Casp8ap2 | 2534 | 0.331 | 0.3425 | Yes |
| 47 | Amd1 | 2536 | 0.331 | 0.3498 | Yes |
| 48 | Pole | 2541 | 0.330 | 0.3569 | Yes |
| 49 | H2az1 | 2570 | 0.328 | 0.3628 | Yes |
| 50 | Sfpq | 2604 | 0.326 | 0.3683 | Yes |
| 51 | Prim2 | 2770 | 0.314 | 0.3668 | Yes |
| 52 | Rad23b | 2782 | 0.313 | 0.3732 | Yes |
| 53 | Cdc45 | 2787 | 0.312 | 0.3799 | Yes |
| 54 | Bub1 | 2817 | 0.310 | 0.3853 | Yes |
| 55 | Srsf10 | 2838 | 0.309 | 0.3911 | Yes |
| 56 | Cdc6 | 2877 | 0.306 | 0.3960 | Yes |
| 57 | Kif11 | 2937 | 0.303 | 0.3996 | Yes |
| 58 | Rad21 | 3056 | 0.297 | 0.4001 | Yes |
| 59 | Syncrip | 3139 | 0.291 | 0.4024 | Yes |
| 60 | Bcl3 | 3179 | 0.288 | 0.4068 | Yes |
| 61 | H2bc12 | 3314 | 0.280 | 0.4061 | Yes |
| 62 | E2f2 | 3406 | 0.276 | 0.4075 | Yes |
| 63 | Mcm5 | 3588 | 0.264 | 0.4040 | Yes |
| 64 | Pola2 | 3642 | 0.261 | 0.4070 | Yes |
| 65 | Tra2b | 3644 | 0.261 | 0.4128 | Yes |
| 66 | Prc1 | 3646 | 0.261 | 0.4186 | Yes |
| 67 | Kif4 | 3685 | 0.258 | 0.4223 | Yes |
| 68 | Ilf3 | 3773 | 0.253 | 0.4234 | Yes |
| 69 | Hus1 | 3779 | 0.252 | 0.4288 | Yes |
| 70 | Ddx39a | 3829 | 0.250 | 0.4318 | Yes |
| 71 | Tle3 | 3893 | 0.245 | 0.4340 | Yes |
| 72 | Suv39h1 | 3899 | 0.244 | 0.4392 | Yes |
| 73 | Lbr | 3914 | 0.244 | 0.4439 | Yes |
| 74 | Fancc | 3964 | 0.241 | 0.4467 | Yes |
| 75 | Orc5 | 4206 | 0.227 | 0.4393 | Yes |
| 76 | Rad54l | 4237 | 0.225 | 0.4427 | Yes |
| 77 | Rbl1 | 4299 | 0.221 | 0.4445 | Yes |
| 78 | Smarcc1 | 4302 | 0.221 | 0.4493 | Yes |
| 79 | Espl1 | 4434 | 0.216 | 0.4473 | Yes |
| 80 | Ccna2 | 4479 | 0.214 | 0.4498 | Yes |
| 81 | Lig3 | 4489 | 0.214 | 0.4541 | Yes |
| 82 | Plk4 | 4490 | 0.214 | 0.4589 | Yes |
| 83 | Cenpe | 4500 | 0.214 | 0.4632 | Yes |
| 84 | Gspt1 | 4542 | 0.211 | 0.4657 | Yes |
| 85 | Hira | 4652 | 0.206 | 0.4647 | Yes |
| 86 | Kif20b | 4656 | 0.206 | 0.4691 | Yes |
| 87 | Knl1 | 4686 | 0.204 | 0.4721 | Yes |
| 88 | Cdkn2c | 4786 | 0.198 | 0.4714 | Yes |
| 89 | Pbk | 4925 | 0.191 | 0.4685 | Yes |
| 90 | Jpt1 | 4926 | 0.191 | 0.4728 | Yes |
| 91 | Ewsr1 | 5047 | 0.187 | 0.4707 | Yes |
| 92 | Cenpf | 5082 | 0.185 | 0.4731 | Yes |
| 93 | Kif15 | 5093 | 0.184 | 0.4766 | Yes |
| 94 | Mad2l1 | 5237 | 0.176 | 0.4732 | Yes |
| 95 | Mapk14 | 5248 | 0.176 | 0.4765 | Yes |
| 96 | Plk1 | 5257 | 0.175 | 0.4800 | Yes |
| 97 | Hmmr | 5491 | 0.163 | 0.4716 | No |
| 98 | Mki67 | 5492 | 0.163 | 0.4752 | No |
| 99 | Brca2 | 5599 | 0.158 | 0.4732 | No |
| 100 | Dbf4 | 5627 | 0.157 | 0.4753 | No |
| 101 | Top1 | 5770 | 0.150 | 0.4713 | No |
| 102 | Cul5 | 5953 | 0.141 | 0.4650 | No |
| 103 | Cbx1 | 5960 | 0.140 | 0.4678 | No |
| 104 | Mtf2 | 6033 | 0.137 | 0.4671 | No |
| 105 | Cks1b | 6054 | 0.136 | 0.4691 | No |
| 106 | Pafah1b1 | 6088 | 0.134 | 0.4704 | No |
| 107 | Smc4 | 6099 | 0.134 | 0.4729 | No |
| 108 | Hmgb3 | 6172 | 0.131 | 0.4721 | No |
| 109 | Chmp1a | 6215 | 0.129 | 0.4728 | No |
| 110 | Ezh2 | 6289 | 0.125 | 0.4718 | No |
| 111 | Aurka | 6290 | 0.125 | 0.4746 | No |
| 112 | Dr1 | 6493 | 0.118 | 0.4667 | No |
| 113 | E2f3 | 6547 | 0.116 | 0.4666 | No |
| 114 | Sap30 | 6647 | 0.112 | 0.4639 | No |
| 115 | Smc2 | 6719 | 0.107 | 0.4626 | No |
| 116 | Stil | 6722 | 0.107 | 0.4649 | No |
| 117 | Cdc25b | 6784 | 0.104 | 0.4641 | No |
| 118 | Ncl | 6862 | 0.100 | 0.4623 | No |
| 119 | Tent4a | 6992 | 0.095 | 0.4577 | No |
| 120 | Cul3 | 7133 | 0.088 | 0.4525 | No |
| 121 | Prpf4b | 7148 | 0.088 | 0.4537 | No |
| 122 | E2f1 | 7229 | 0.084 | 0.4514 | No |
| 123 | Smad3 | 7271 | 0.083 | 0.4512 | No |
| 124 | Pds5b | 7311 | 0.081 | 0.4509 | No |
| 125 | Kif5b | 7349 | 0.080 | 0.4508 | No |
| 126 | Tpx2 | 7415 | 0.078 | 0.4492 | No |
| 127 | Egf | 7481 | 0.076 | 0.4475 | No |
| 128 | Ccnf | 7605 | 0.071 | 0.4427 | No |
| 129 | Cdk1 | 7652 | 0.070 | 0.4419 | No |
| 130 | Birc5 | 7753 | 0.065 | 0.4382 | No |
| 131 | Atrx | 8046 | 0.053 | 0.4242 | No |
| 132 | Ctcf | 8052 | 0.053 | 0.4251 | No |
| 133 | Ythdc1 | 8140 | 0.050 | 0.4217 | No |
| 134 | Ttk | 8144 | 0.049 | 0.4227 | No |
| 135 | Notch2 | 8243 | 0.045 | 0.4186 | No |
| 136 | Nolc1 | 8285 | 0.044 | 0.4175 | No |
| 137 | Marcks | 8324 | 0.042 | 0.4164 | No |
| 138 | H2az2 | 8337 | 0.042 | 0.4167 | No |
| 139 | Ss18 | 8398 | 0.039 | 0.4145 | No |
| 140 | Ccnb2 | 8508 | 0.035 | 0.4096 | No |
| 141 | Polq | 8621 | 0.029 | 0.4045 | No |
| 142 | Slc12a2 | 8645 | 0.029 | 0.4039 | No |
| 143 | Ube2s | 8668 | 0.028 | 0.4034 | No |
| 144 | Map3k20 | 8712 | 0.026 | 0.4018 | No |
| 145 | Nusap1 | 8762 | 0.024 | 0.3998 | No |
| 146 | Troap | 8884 | 0.018 | 0.3939 | No |
| 147 | Snrpd1 | 8951 | 0.017 | 0.3909 | No |
| 148 | Hif1a | 9076 | 0.013 | 0.3847 | No |
| 149 | Stag1 | 9085 | 0.013 | 0.3846 | No |
| 150 | Gins2 | 9139 | 0.010 | 0.3821 | No |
| 151 | Wrn | 9312 | 0.004 | 0.3733 | No |
| 152 | Hmga1b | 9371 | 0.002 | 0.3703 | No |
| 153 | Odf2 | 9792 | -0.012 | 0.3488 | No |
| 154 | Abl1 | 9872 | -0.015 | 0.3451 | No |
| 155 | Nek2 | 10160 | -0.027 | 0.3308 | No |
| 156 | Srsf2 | 10201 | -0.028 | 0.3294 | No |
| 157 | Cdc20 | 10289 | -0.032 | 0.3256 | No |
| 158 | Slc7a1 | 10474 | -0.040 | 0.3169 | No |
| 159 | Mnat1 | 10641 | -0.045 | 0.3094 | No |
| 160 | Slc38a1 | 11011 | -0.060 | 0.2916 | No |
| 161 | Cdc27 | 11196 | -0.068 | 0.2836 | No |
| 162 | Cdkn1b | 11230 | -0.069 | 0.2834 | No |
| 163 | Arid4a | 11299 | -0.071 | 0.2815 | No |
| 164 | Cenpa | 11523 | -0.080 | 0.2717 | No |
| 165 | Ccnd1 | 11588 | -0.083 | 0.2702 | No |
| 166 | Foxn3 | 11787 | -0.092 | 0.2621 | No |
| 167 | Pml | 11852 | -0.096 | 0.2609 | No |
| 168 | Traip | 11855 | -0.096 | 0.2629 | No |
| 169 | Rps6ka5 | 12029 | -0.103 | 0.2562 | No |
| 170 | Ccnt1 | 12211 | -0.110 | 0.2493 | No |
| 171 | Cul4a | 12445 | -0.120 | 0.2399 | No |
| 172 | Orc6 | 12877 | -0.136 | 0.2206 | No |
| 173 | Rpa2 | 13007 | -0.141 | 0.2171 | No |
| 174 | Meis1 | 13059 | -0.144 | 0.2177 | No |
| 175 | Nup50 | 13062 | -0.144 | 0.2207 | No |
| 176 | Cks2 | 13334 | -0.157 | 0.2102 | No |
| 177 | Pura | 13338 | -0.157 | 0.2136 | No |
| 178 | Ube2c | 13615 | -0.170 | 0.2031 | No |
| 179 | Tnpo2 | 13644 | -0.171 | 0.2054 | No |
| 180 | Slc7a5 | 14235 | -0.198 | 0.1793 | No |
| 181 | Dkc1 | 14337 | -0.203 | 0.1786 | No |
| 182 | Atf5 | 14556 | -0.214 | 0.1721 | No |
| 183 | Cdk4 | 14936 | -0.233 | 0.1576 | No |
| 184 | H2ax | 15101 | -0.242 | 0.1545 | No |
| 185 | E2f4 | 15113 | -0.243 | 0.1594 | No |
| 186 | Pttg1 | 15368 | -0.255 | 0.1519 | No |
| 187 | Meis2 | 15522 | -0.264 | 0.1498 | No |
| 188 | Dmd | 15622 | -0.270 | 0.1507 | No |
| 189 | Tgfb1 | 16282 | -0.307 | 0.1235 | No |
| 190 | Myc | 17043 | -0.358 | 0.0921 | No |
| 191 | Bub3 | 17154 | -0.365 | 0.0945 | No |
| 192 | Katna1 | 17325 | -0.378 | 0.0941 | No |
| 193 | Kmt5a | 17840 | -0.426 | 0.0770 | No |
| 194 | Cdkn3 | 17874 | -0.429 | 0.0848 | No |

