| Dataset | MPP.MPP_Pheno.cls#Group2_versus_Group4.MPP_Pheno.cls#Group2_versus_Group4_repos |
| Phenotype | MPP_Pheno.cls#Group2_versus_Group4_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | 0.5010843 |
| Normalized Enrichment Score (NES) | 1.4480926 |
| Nominal p-value | 0.17165668 |
| FDR q-value | 0.62221295 |
| FWER p-Value | 0.54 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Dck | 152 | 0.777 | 0.0074 | Yes |
| 2 | Dnmt1 | 263 | 0.690 | 0.0152 | Yes |
| 3 | Mcm2 | 306 | 0.668 | 0.0262 | Yes |
| 4 | Racgap1 | 328 | 0.656 | 0.0380 | Yes |
| 5 | Mcm4 | 424 | 0.619 | 0.0452 | Yes |
| 6 | Ipo7 | 443 | 0.614 | 0.0563 | Yes |
| 7 | Rbbp7 | 456 | 0.610 | 0.0677 | Yes |
| 8 | Srsf1 | 487 | 0.600 | 0.0779 | Yes |
| 9 | Lmnb1 | 499 | 0.595 | 0.0890 | Yes |
| 10 | Hells | 516 | 0.590 | 0.0998 | Yes |
| 11 | Cdca8 | 532 | 0.585 | 0.1105 | Yes |
| 12 | Rad51ap1 | 537 | 0.584 | 0.1217 | Yes |
| 13 | Shmt1 | 594 | 0.574 | 0.1301 | Yes |
| 14 | Ubr7 | 610 | 0.570 | 0.1405 | Yes |
| 15 | Xpo1 | 700 | 0.546 | 0.1466 | Yes |
| 16 | Ncapd2 | 831 | 0.526 | 0.1502 | Yes |
| 17 | Spc25 | 876 | 0.517 | 0.1581 | Yes |
| 18 | Timeless | 881 | 0.516 | 0.1680 | Yes |
| 19 | Mcm6 | 1017 | 0.493 | 0.1707 | Yes |
| 20 | Psmc3ip | 1018 | 0.493 | 0.1804 | Yes |
| 21 | Rpa3 | 1168 | 0.472 | 0.1819 | Yes |
| 22 | Atad2 | 1177 | 0.469 | 0.1907 | Yes |
| 23 | Zw10 | 1210 | 0.465 | 0.1982 | Yes |
| 24 | Nasp | 1221 | 0.463 | 0.2068 | Yes |
| 25 | Ung | 1347 | 0.448 | 0.2091 | Yes |
| 26 | Mcm3 | 1359 | 0.447 | 0.2173 | Yes |
| 27 | Lig1 | 1368 | 0.446 | 0.2256 | Yes |
| 28 | Cse1l | 1391 | 0.444 | 0.2332 | Yes |
| 29 | Cdkn1a | 1446 | 0.437 | 0.2390 | Yes |
| 30 | Wdr90 | 1485 | 0.430 | 0.2454 | Yes |
| 31 | Slbp | 1492 | 0.429 | 0.2536 | Yes |
| 32 | Cdc25a | 1496 | 0.429 | 0.2618 | Yes |
| 33 | Top2a | 1512 | 0.428 | 0.2695 | Yes |
| 34 | Brca1 | 1523 | 0.427 | 0.2773 | Yes |
| 35 | Bard1 | 1542 | 0.424 | 0.2847 | Yes |
| 36 | Hnrnpd | 1547 | 0.423 | 0.2928 | Yes |
| 37 | Smc3 | 1619 | 0.415 | 0.2973 | Yes |
| 38 | Chek1 | 1639 | 0.413 | 0.3044 | Yes |
| 39 | Aurkb | 1780 | 0.399 | 0.3050 | Yes |
| 40 | Melk | 1809 | 0.396 | 0.3113 | Yes |
| 41 | Smc1a | 1823 | 0.395 | 0.3184 | Yes |
| 42 | Tacc3 | 1833 | 0.395 | 0.3257 | Yes |
| 43 | Kif2c | 1859 | 0.392 | 0.3321 | Yes |
| 44 | Tmpo | 1892 | 0.389 | 0.3381 | Yes |
| 45 | Cnot9 | 1933 | 0.384 | 0.3435 | Yes |
| 46 | Stmn1 | 1981 | 0.379 | 0.3485 | Yes |
| 47 | Msh2 | 2083 | 0.368 | 0.3505 | Yes |
| 48 | Bub1b | 2098 | 0.367 | 0.3570 | Yes |
| 49 | Asf1b | 2274 | 0.350 | 0.3548 | Yes |
| 50 | Mybl2 | 2343 | 0.345 | 0.3580 | Yes |
| 51 | Kif22 | 2439 | 0.337 | 0.3597 | Yes |
| 52 | Eed | 2455 | 0.336 | 0.3656 | Yes |
| 53 | Cdkn2a | 2493 | 0.334 | 0.3702 | Yes |
| 54 | Nap1l1 | 2505 | 0.333 | 0.3762 | Yes |
| 55 | Pole | 2541 | 0.330 | 0.3809 | Yes |
| 56 | Ccp110 | 2569 | 0.328 | 0.3859 | Yes |
| 57 | H2az1 | 2570 | 0.328 | 0.3924 | Yes |
| 58 | Dut | 2631 | 0.324 | 0.3956 | Yes |
| 59 | Rad51c | 2733 | 0.316 | 0.3966 | Yes |
| 60 | Nbn | 2751 | 0.314 | 0.4019 | Yes |
| 61 | Prim2 | 2770 | 0.314 | 0.4071 | Yes |
| 62 | Prps1 | 2832 | 0.309 | 0.4100 | Yes |
| 63 | Tfrc | 2900 | 0.305 | 0.4125 | Yes |
| 64 | Rpa1 | 2933 | 0.303 | 0.4168 | Yes |
| 65 | Prkdc | 2955 | 0.301 | 0.4216 | Yes |
| 66 | Tcf19 | 2982 | 0.301 | 0.4262 | Yes |
| 67 | Ssrp1 | 2990 | 0.300 | 0.4317 | Yes |
| 68 | Rad21 | 3056 | 0.297 | 0.4342 | Yes |
| 69 | Tubb5 | 3095 | 0.294 | 0.4380 | Yes |
| 70 | Syncrip | 3139 | 0.291 | 0.4415 | Yes |
| 71 | Nop56 | 3478 | 0.272 | 0.4293 | Yes |
| 72 | Mcm5 | 3588 | 0.264 | 0.4289 | Yes |
| 73 | Pola2 | 3642 | 0.261 | 0.4312 | Yes |
| 74 | Tra2b | 3644 | 0.261 | 0.4363 | Yes |
| 75 | Gins4 | 3649 | 0.260 | 0.4412 | Yes |
| 76 | Mre11a | 3681 | 0.258 | 0.4447 | Yes |
| 77 | Kif4 | 3685 | 0.258 | 0.4496 | Yes |
| 78 | Ilf3 | 3773 | 0.253 | 0.4500 | Yes |
| 79 | Chek2 | 3778 | 0.252 | 0.4548 | Yes |
| 80 | Hus1 | 3779 | 0.252 | 0.4597 | Yes |
| 81 | Ddx39a | 3829 | 0.250 | 0.4621 | Yes |
| 82 | Suv39h1 | 3899 | 0.244 | 0.4633 | Yes |
| 83 | Lbr | 3914 | 0.244 | 0.4674 | Yes |
| 84 | Anp32e | 4029 | 0.238 | 0.4661 | Yes |
| 85 | Cbx5 | 4057 | 0.236 | 0.4694 | Yes |
| 86 | Tk1 | 4150 | 0.230 | 0.4691 | Yes |
| 87 | Espl1 | 4434 | 0.216 | 0.4587 | Yes |
| 88 | Plk4 | 4490 | 0.214 | 0.4601 | Yes |
| 89 | Cenpe | 4500 | 0.214 | 0.4638 | Yes |
| 90 | Usp1 | 4504 | 0.213 | 0.4678 | Yes |
| 91 | Gspt1 | 4542 | 0.211 | 0.4701 | Yes |
| 92 | Mms22l | 4549 | 0.211 | 0.4739 | Yes |
| 93 | Ak2 | 4666 | 0.205 | 0.4719 | Yes |
| 94 | Mcm7 | 4783 | 0.198 | 0.4698 | Yes |
| 95 | Cdkn2c | 4786 | 0.198 | 0.4736 | Yes |
| 96 | Nup205 | 4788 | 0.198 | 0.4774 | Yes |
| 97 | Rrm2 | 4867 | 0.194 | 0.4772 | Yes |
| 98 | Donson | 4881 | 0.193 | 0.4803 | Yes |
| 99 | Jpt1 | 4926 | 0.191 | 0.4818 | Yes |
| 100 | Hmgb2 | 4980 | 0.188 | 0.4827 | Yes |
| 101 | Spag5 | 5080 | 0.185 | 0.4812 | Yes |
| 102 | Cdca3 | 5084 | 0.185 | 0.4847 | Yes |
| 103 | Pcna | 5182 | 0.179 | 0.4832 | Yes |
| 104 | Nup107 | 5206 | 0.178 | 0.4855 | Yes |
| 105 | Mad2l1 | 5237 | 0.176 | 0.4874 | Yes |
| 106 | Plk1 | 5257 | 0.175 | 0.4899 | Yes |
| 107 | Pold1 | 5434 | 0.166 | 0.4840 | Yes |
| 108 | Pnn | 5446 | 0.165 | 0.4867 | Yes |
| 109 | Hmmr | 5491 | 0.163 | 0.4876 | Yes |
| 110 | Mki67 | 5492 | 0.163 | 0.4908 | Yes |
| 111 | Lyar | 5500 | 0.162 | 0.4936 | Yes |
| 112 | Brca2 | 5599 | 0.158 | 0.4916 | Yes |
| 113 | Lsm8 | 5721 | 0.153 | 0.4884 | Yes |
| 114 | Mlh1 | 5723 | 0.152 | 0.4913 | Yes |
| 115 | Rfc1 | 5764 | 0.151 | 0.4922 | Yes |
| 116 | Pold3 | 5787 | 0.149 | 0.4940 | Yes |
| 117 | Ppp1r8 | 5800 | 0.148 | 0.4963 | Yes |
| 118 | Cit | 5813 | 0.148 | 0.4985 | Yes |
| 119 | Wee1 | 5877 | 0.145 | 0.4981 | Yes |
| 120 | Cks1b | 6054 | 0.136 | 0.4917 | Yes |
| 121 | Psip1 | 6064 | 0.135 | 0.4939 | Yes |
| 122 | Smc4 | 6099 | 0.134 | 0.4947 | Yes |
| 123 | Spc24 | 6134 | 0.133 | 0.4956 | Yes |
| 124 | Cenpm | 6164 | 0.131 | 0.4967 | Yes |
| 125 | Hmgb3 | 6172 | 0.131 | 0.4989 | Yes |
| 126 | Eif2s1 | 6180 | 0.131 | 0.5011 | Yes |
| 127 | Ezh2 | 6289 | 0.125 | 0.4980 | No |
| 128 | Aurka | 6290 | 0.125 | 0.5004 | No |
| 129 | Diaph3 | 6551 | 0.116 | 0.4892 | No |
| 130 | Paics | 6578 | 0.115 | 0.4901 | No |
| 131 | Ranbp1 | 6739 | 0.107 | 0.4839 | No |
| 132 | Rfc3 | 6782 | 0.104 | 0.4838 | No |
| 133 | Cdc25b | 6784 | 0.104 | 0.4858 | No |
| 134 | Ube2t | 6850 | 0.101 | 0.4844 | No |
| 135 | Nudt21 | 7079 | 0.091 | 0.4744 | No |
| 136 | Prdx4 | 7151 | 0.088 | 0.4724 | No |
| 137 | Pds5b | 7311 | 0.081 | 0.4658 | No |
| 138 | Dlgap5 | 7524 | 0.074 | 0.4563 | No |
| 139 | Brms1l | 7581 | 0.072 | 0.4548 | No |
| 140 | Cdk1 | 7652 | 0.070 | 0.4525 | No |
| 141 | Birc5 | 7753 | 0.065 | 0.4486 | No |
| 142 | Rad50 | 7789 | 0.065 | 0.4481 | No |
| 143 | E2f8 | 7829 | 0.063 | 0.4473 | No |
| 144 | Dek | 8006 | 0.055 | 0.4393 | No |
| 145 | Ctcf | 8052 | 0.053 | 0.4380 | No |
| 146 | Tbrg4 | 8104 | 0.051 | 0.4363 | No |
| 147 | Ccne1 | 8105 | 0.051 | 0.4373 | No |
| 148 | Nolc1 | 8285 | 0.044 | 0.4289 | No |
| 149 | Ccnb2 | 8508 | 0.035 | 0.4181 | No |
| 150 | Trip13 | 8619 | 0.029 | 0.4130 | No |
| 151 | Ube2s | 8668 | 0.028 | 0.4110 | No |
| 152 | Gins3 | 8962 | 0.016 | 0.3962 | No |
| 153 | Smc6 | 8996 | 0.015 | 0.3948 | No |
| 154 | Ran | 9040 | 0.014 | 0.3928 | No |
| 155 | Stag1 | 9085 | 0.013 | 0.3908 | No |
| 156 | Mxd3 | 9100 | 0.012 | 0.3903 | No |
| 157 | Pole4 | 9169 | 0.009 | 0.3870 | No |
| 158 | Hmga1b | 9371 | 0.002 | 0.3766 | No |
| 159 | Orc2 | 9775 | -0.011 | 0.3560 | No |
| 160 | Dclre1b | 10045 | -0.022 | 0.3425 | No |
| 161 | Depdc1a | 10086 | -0.023 | 0.3409 | No |
| 162 | Srsf2 | 10201 | -0.028 | 0.3355 | No |
| 163 | Luc7l3 | 10208 | -0.029 | 0.3358 | No |
| 164 | Cdc20 | 10289 | -0.032 | 0.3322 | No |
| 165 | Xrcc6 | 10776 | -0.051 | 0.3081 | No |
| 166 | Asf1a | 11194 | -0.068 | 0.2878 | No |
| 167 | Cdkn1b | 11230 | -0.069 | 0.2874 | No |
| 168 | Ing3 | 11356 | -0.073 | 0.2823 | No |
| 169 | Exosc8 | 11833 | -0.095 | 0.2595 | No |
| 170 | Nme1 | 11923 | -0.098 | 0.2569 | No |
| 171 | Phf5a | 11925 | -0.098 | 0.2587 | No |
| 172 | Gins1 | 11957 | -0.099 | 0.2591 | No |
| 173 | Pa2g4 | 12404 | -0.118 | 0.2383 | No |
| 174 | Nup153 | 12664 | -0.127 | 0.2274 | No |
| 175 | Tipin | 12772 | -0.132 | 0.2245 | No |
| 176 | Orc6 | 12877 | -0.136 | 0.2217 | No |
| 177 | Rpa2 | 13007 | -0.141 | 0.2178 | No |
| 178 | Pold2 | 13305 | -0.155 | 0.2055 | No |
| 179 | Cks2 | 13334 | -0.157 | 0.2071 | No |
| 180 | Kif18b | 13414 | -0.161 | 0.2062 | No |
| 181 | Rfc2 | 14061 | -0.190 | 0.1765 | No |
| 182 | Tubg1 | 14452 | -0.209 | 0.1604 | No |
| 183 | Cdk4 | 14936 | -0.233 | 0.1400 | No |
| 184 | H2ax | 15101 | -0.242 | 0.1362 | No |
| 185 | Ppm1d | 15184 | -0.246 | 0.1368 | No |
| 186 | Dctpp1 | 15231 | -0.249 | 0.1393 | No |
| 187 | Pttg1 | 15368 | -0.255 | 0.1373 | No |
| 188 | Mthfd2 | 15753 | -0.278 | 0.1229 | No |
| 189 | Dscc1 | 15774 | -0.280 | 0.1273 | No |
| 190 | Pan2 | 15830 | -0.283 | 0.1300 | No |
| 191 | Rnaseh2a | 16143 | -0.301 | 0.1198 | No |
| 192 | Pms2 | 16327 | -0.311 | 0.1164 | No |
| 193 | Trp53 | 16451 | -0.318 | 0.1163 | No |
| 194 | Snrpb | 16817 | -0.341 | 0.1041 | No |
| 195 | Rad1 | 16987 | -0.354 | 0.1023 | No |
| 196 | Myc | 17043 | -0.358 | 0.1065 | No |
| 197 | Cdkn3 | 17874 | -0.429 | 0.0719 | No |
| 198 | Pop7 | 19115 | -0.655 | 0.0206 | No |

