| Dataset | MPP.MPP_Pheno.cls#Group2_versus_Group4.MPP_Pheno.cls#Group2_versus_Group4_repos |
| Phenotype | MPP_Pheno.cls#Group2_versus_Group4_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_DNA_REPAIR |
| Enrichment Score (ES) | 0.20857906 |
| Normalized Enrichment Score (NES) | 0.8982049 |
| Nominal p-value | 0.61290324 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Rad51 | 186 | 0.745 | 0.0119 | Yes |
| 2 | Gtf2f1 | 224 | 0.713 | 0.0305 | Yes |
| 3 | Polr2k | 296 | 0.671 | 0.0462 | Yes |
| 4 | Cda | 403 | 0.627 | 0.0587 | Yes |
| 5 | Ddb1 | 613 | 0.569 | 0.0644 | Yes |
| 6 | Srsf6 | 707 | 0.546 | 0.0753 | Yes |
| 7 | Dgcr8 | 745 | 0.539 | 0.0889 | Yes |
| 8 | Supt4a | 754 | 0.537 | 0.1039 | Yes |
| 9 | Umps | 836 | 0.525 | 0.1149 | Yes |
| 10 | Pde6g | 904 | 0.512 | 0.1262 | Yes |
| 11 | Rpa3 | 1168 | 0.472 | 0.1262 | Yes |
| 12 | Taf9 | 1283 | 0.456 | 0.1334 | Yes |
| 13 | Lig1 | 1368 | 0.446 | 0.1419 | Yes |
| 14 | Nelfb | 1484 | 0.430 | 0.1484 | Yes |
| 15 | Rfc4 | 1655 | 0.411 | 0.1514 | Yes |
| 16 | Npr2 | 1751 | 0.402 | 0.1581 | Yes |
| 17 | Polr2a | 1874 | 0.391 | 0.1631 | Yes |
| 18 | Impdh2 | 2059 | 0.371 | 0.1642 | Yes |
| 19 | Prim1 | 2325 | 0.346 | 0.1605 | Yes |
| 20 | Brf2 | 2327 | 0.346 | 0.1704 | Yes |
| 21 | Ak1 | 2469 | 0.336 | 0.1728 | Yes |
| 22 | Dut | 2631 | 0.324 | 0.1739 | Yes |
| 23 | Ssrp1 | 2990 | 0.300 | 0.1640 | Yes |
| 24 | Gtf2a2 | 3130 | 0.292 | 0.1652 | Yes |
| 25 | Tarbp2 | 3168 | 0.289 | 0.1717 | Yes |
| 26 | Pola1 | 3419 | 0.276 | 0.1667 | Yes |
| 27 | Pnp | 3433 | 0.275 | 0.1739 | Yes |
| 28 | Usp11 | 3494 | 0.271 | 0.1786 | Yes |
| 29 | Gtf2h1 | 3506 | 0.270 | 0.1858 | Yes |
| 30 | Smad5 | 3560 | 0.266 | 0.1907 | Yes |
| 31 | Stx3 | 3561 | 0.265 | 0.1984 | Yes |
| 32 | Pola2 | 3642 | 0.261 | 0.2018 | Yes |
| 33 | Sf3a3 | 3692 | 0.257 | 0.2067 | Yes |
| 34 | Taf12 | 3796 | 0.251 | 0.2086 | Yes |
| 35 | Polr1d | 4129 | 0.232 | 0.1981 | No |
| 36 | Supt5 | 4400 | 0.218 | 0.1904 | No |
| 37 | Snapc4 | 4427 | 0.216 | 0.1953 | No |
| 38 | Xpc | 4473 | 0.215 | 0.1992 | No |
| 39 | Taf6 | 5056 | 0.186 | 0.1745 | No |
| 40 | Pcna | 5182 | 0.179 | 0.1732 | No |
| 41 | Mrpl40 | 5207 | 0.178 | 0.1771 | No |
| 42 | Zwint | 5407 | 0.167 | 0.1716 | No |
| 43 | Pold1 | 5434 | 0.166 | 0.1751 | No |
| 44 | Sdcbp | 5437 | 0.166 | 0.1798 | No |
| 45 | Nt5c3 | 5506 | 0.162 | 0.1809 | No |
| 46 | Gpx4 | 5676 | 0.154 | 0.1766 | No |
| 47 | Polr1c | 5718 | 0.153 | 0.1789 | No |
| 48 | Pold3 | 5787 | 0.149 | 0.1797 | No |
| 49 | Rfc5 | 6191 | 0.130 | 0.1626 | No |
| 50 | Hcls1 | 6293 | 0.125 | 0.1610 | No |
| 51 | Ak3 | 6680 | 0.109 | 0.1442 | No |
| 52 | Tsg101 | 6689 | 0.109 | 0.1470 | No |
| 53 | Rfc3 | 6782 | 0.104 | 0.1452 | No |
| 54 | Bcap31 | 6984 | 0.095 | 0.1376 | No |
| 55 | Nudt21 | 7079 | 0.091 | 0.1353 | No |
| 56 | Poll | 7081 | 0.091 | 0.1379 | No |
| 57 | Nt5c | 7123 | 0.089 | 0.1383 | No |
| 58 | Nudt9 | 7256 | 0.083 | 0.1339 | No |
| 59 | Alyref | 7258 | 0.083 | 0.1363 | No |
| 60 | Cox17 | 7498 | 0.075 | 0.1261 | No |
| 61 | Aaas | 7580 | 0.072 | 0.1240 | No |
| 62 | Polr2d | 7595 | 0.071 | 0.1253 | No |
| 63 | Ada | 7646 | 0.070 | 0.1247 | No |
| 64 | Rnmt | 8057 | 0.053 | 0.1051 | No |
| 65 | Rbx1 | 8158 | 0.049 | 0.1013 | No |
| 66 | Vps37b | 8174 | 0.048 | 0.1019 | No |
| 67 | Fen1 | 8226 | 0.046 | 0.1006 | No |
| 68 | Gtf2b | 8335 | 0.042 | 0.0963 | No |
| 69 | Adrm1 | 8462 | 0.036 | 0.0908 | No |
| 70 | Rrm2b | 8547 | 0.033 | 0.0874 | No |
| 71 | Itpa | 8568 | 0.032 | 0.0873 | No |
| 72 | Pom121 | 8651 | 0.028 | 0.0839 | No |
| 73 | Ercc4 | 8714 | 0.026 | 0.0814 | No |
| 74 | Ercc3 | 8755 | 0.024 | 0.0801 | No |
| 75 | Cstf3 | 8788 | 0.023 | 0.0791 | No |
| 76 | Polr2f | 9094 | 0.012 | 0.0637 | No |
| 77 | Pole4 | 9169 | 0.009 | 0.0601 | No |
| 78 | Pold4 | 9199 | 0.008 | 0.0589 | No |
| 79 | Cmpk2 | 9240 | 0.007 | 0.0570 | No |
| 80 | Polh | 9303 | 0.005 | 0.0539 | No |
| 81 | Gtf2h3 | 9847 | -0.014 | 0.0263 | No |
| 82 | Ercc1 | 9848 | -0.014 | 0.0267 | No |
| 83 | Tyms | 9974 | -0.020 | 0.0208 | No |
| 84 | Nme3 | 9991 | -0.020 | 0.0206 | No |
| 85 | Polr3c | 10159 | -0.027 | 0.0127 | No |
| 86 | Edf1 | 10359 | -0.035 | 0.0034 | No |
| 87 | Eloa | 10495 | -0.040 | -0.0024 | No |
| 88 | Gtf3c5 | 10634 | -0.045 | -0.0082 | No |
| 89 | Nelfcd | 10694 | -0.047 | -0.0099 | No |
| 90 | Nme4 | 10704 | -0.048 | -0.0090 | No |
| 91 | Zfp707 | 10855 | -0.054 | -0.0152 | No |
| 92 | Tk2 | 10856 | -0.054 | -0.0136 | No |
| 93 | Ercc8 | 11168 | -0.067 | -0.0277 | No |
| 94 | Ddb2 | 11259 | -0.070 | -0.0304 | No |
| 95 | Ercc2 | 11386 | -0.075 | -0.0347 | No |
| 96 | Gsdme | 11604 | -0.084 | -0.0435 | No |
| 97 | Nfx1 | 11795 | -0.093 | -0.0507 | No |
| 98 | Nme1 | 11923 | -0.098 | -0.0544 | No |
| 99 | Nelfe | 11936 | -0.099 | -0.0522 | No |
| 100 | Dctn4 | 12019 | -0.102 | -0.0535 | No |
| 101 | Pde4b | 12043 | -0.103 | -0.0517 | No |
| 102 | Polr2i | 12060 | -0.105 | -0.0495 | No |
| 103 | Taf1c | 12400 | -0.118 | -0.0636 | No |
| 104 | Taf13 | 12483 | -0.121 | -0.0643 | No |
| 105 | Snapc5 | 12755 | -0.131 | -0.0745 | No |
| 106 | Rpa2 | 13007 | -0.141 | -0.0834 | No |
| 107 | Gmpr2 | 13144 | -0.147 | -0.0862 | No |
| 108 | Cetn2 | 13212 | -0.151 | -0.0853 | No |
| 109 | Ncbp2 | 13229 | -0.151 | -0.0818 | No |
| 110 | Rala | 13513 | -0.166 | -0.0916 | No |
| 111 | Polr1h | 13637 | -0.171 | -0.0931 | No |
| 112 | Polr2j | 13706 | -0.173 | -0.0916 | No |
| 113 | Rfc2 | 14061 | -0.190 | -0.1044 | No |
| 114 | Dguok | 14341 | -0.203 | -0.1129 | No |
| 115 | Adcy6 | 14543 | -0.213 | -0.1172 | No |
| 116 | Gtf2h5 | 14667 | -0.220 | -0.1172 | No |
| 117 | Mpc2 | 15825 | -0.283 | -0.1688 | No |
| 118 | Clp1 | 15917 | -0.288 | -0.1652 | No |
| 119 | Upf3b | 15922 | -0.288 | -0.1571 | No |
| 120 | Surf1 | 16088 | -0.298 | -0.1570 | No |
| 121 | Polr2e | 16192 | -0.302 | -0.1537 | No |
| 122 | Rev3l | 16237 | -0.304 | -0.1472 | No |
| 123 | Ercc5 | 16287 | -0.308 | -0.1408 | No |
| 124 | Trp53 | 16451 | -0.318 | -0.1401 | No |
| 125 | Sec61a1 | 16537 | -0.322 | -0.1352 | No |
| 126 | Ell | 16976 | -0.353 | -0.1476 | No |
| 127 | Arl6ip1 | 17066 | -0.360 | -0.1419 | No |
| 128 | Rad52 | 17217 | -0.370 | -0.1390 | No |
| 129 | Rae1 | 17281 | -0.375 | -0.1314 | No |
| 130 | Ago4 | 17414 | -0.386 | -0.1271 | No |
| 131 | Polb | 17548 | -0.398 | -0.1225 | No |
| 132 | Eif1b | 17839 | -0.425 | -0.1253 | No |
| 133 | Polr2c | 17982 | -0.440 | -0.1199 | No |
| 134 | Aprt | 18240 | -0.470 | -0.1196 | No |
| 135 | Guk1 | 18262 | -0.472 | -0.1071 | No |
| 136 | Sac3d1 | 18284 | -0.475 | -0.0945 | No |
| 137 | Polr3gl | 18370 | -0.487 | -0.0849 | No |
| 138 | Mpg | 18556 | -0.517 | -0.0796 | No |
| 139 | Cant1 | 18606 | -0.525 | -0.0670 | No |
| 140 | Dad1 | 18805 | -0.561 | -0.0610 | No |
| 141 | Bcam | 18807 | -0.562 | -0.0449 | No |
| 142 | Vps28 | 19044 | -0.629 | -0.0390 | No |
| 143 | Polr2h | 19205 | -0.694 | -0.0272 | No |
| 144 | Polr2g | 19246 | -0.719 | -0.0086 | No |
| 145 | Taf10 | 19312 | -0.773 | 0.0103 | No |

