| Dataset | MPP.MPP_Pheno.cls#Group1_versus_Group4.MPP_Pheno.cls#Group1_versus_Group4_repos |
| Phenotype | MPP_Pheno.cls#Group1_versus_Group4_repos |
| Upregulated in class | 3 |
| GeneSet | HALLMARK_OXIDATIVE_PHOSPHORYLATION |
| Enrichment Score (ES) | -0.40450293 |
| Normalized Enrichment Score (NES) | -1.5729618 |
| Nominal p-value | 0.046511628 |
| FDR q-value | 0.17238173 |
| FWER p-Value | 0.262 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Atp6v0c | 553 | 0.579 | -0.0163 | No |
| 2 | Gpx4 | 777 | 0.528 | -0.0166 | No |
| 3 | Lrpprc | 836 | 0.516 | -0.0086 | No |
| 4 | Mrps12 | 1089 | 0.479 | -0.0114 | No |
| 5 | Uqcrq | 1535 | 0.425 | -0.0254 | No |
| 6 | Dlst | 1561 | 0.422 | -0.0177 | No |
| 7 | Mtrr | 1634 | 0.413 | -0.0126 | No |
| 8 | Mrpl11 | 1856 | 0.392 | -0.0157 | No |
| 9 | Mrps22 | 1866 | 0.391 | -0.0078 | No |
| 10 | Pmpca | 1971 | 0.382 | -0.0051 | No |
| 11 | Pdha1 | 2088 | 0.369 | -0.0032 | No |
| 12 | Hspa9 | 2311 | 0.352 | -0.0072 | No |
| 13 | Por | 2678 | 0.322 | -0.0193 | No |
| 14 | Ndufa7 | 2868 | 0.311 | -0.0224 | No |
| 15 | Hadhb | 3025 | 0.304 | -0.0240 | No |
| 16 | Dlat | 3186 | 0.293 | -0.0260 | No |
| 17 | Fh1 | 3241 | 0.289 | -0.0227 | No |
| 18 | Cox10 | 3392 | 0.279 | -0.0245 | No |
| 19 | Gpi1 | 3702 | 0.257 | -0.0350 | No |
| 20 | Vdac3 | 3775 | 0.252 | -0.0334 | No |
| 21 | Vdac2 | 4202 | 0.228 | -0.0505 | No |
| 22 | Atp6v1g1 | 4315 | 0.221 | -0.0516 | No |
| 23 | Pdhx | 4381 | 0.218 | -0.0503 | No |
| 24 | Pdp1 | 4580 | 0.208 | -0.0562 | No |
| 25 | Alas1 | 4624 | 0.206 | -0.0540 | No |
| 26 | Mrps15 | 4830 | 0.196 | -0.0604 | No |
| 27 | Mrpl35 | 4875 | 0.194 | -0.0586 | No |
| 28 | Mfn2 | 5245 | 0.178 | -0.0739 | No |
| 29 | Atp6v1h | 5311 | 0.174 | -0.0735 | No |
| 30 | Mtx2 | 5436 | 0.167 | -0.0764 | No |
| 31 | Atp6v1c1 | 5585 | 0.161 | -0.0806 | No |
| 32 | Cox6b1 | 5720 | 0.154 | -0.0842 | No |
| 33 | Dld | 5809 | 0.149 | -0.0856 | No |
| 34 | Afg3l2 | 5860 | 0.147 | -0.0851 | No |
| 35 | Fxn | 5989 | 0.141 | -0.0887 | No |
| 36 | Cox7c | 6242 | 0.129 | -0.0990 | No |
| 37 | Immt | 7078 | 0.095 | -0.1401 | No |
| 38 | Vdac1 | 7102 | 0.095 | -0.1393 | No |
| 39 | Mpc1 | 7254 | 0.089 | -0.1452 | No |
| 40 | Slc25a20 | 7432 | 0.081 | -0.1527 | No |
| 41 | Opa1 | 7623 | 0.073 | -0.1609 | No |
| 42 | Nnt | 7671 | 0.070 | -0.1619 | No |
| 43 | Ndufs7 | 7979 | 0.057 | -0.1765 | No |
| 44 | Cox7a2 | 7988 | 0.056 | -0.1758 | No |
| 45 | Cox15 | 8011 | 0.055 | -0.1757 | No |
| 46 | Got2 | 8035 | 0.054 | -0.1757 | No |
| 47 | Sucla2 | 8189 | 0.049 | -0.1826 | No |
| 48 | Acaa1a | 8198 | 0.049 | -0.1820 | No |
| 49 | Tomm70a | 8240 | 0.046 | -0.1831 | No |
| 50 | Idh3a | 8315 | 0.043 | -0.1860 | No |
| 51 | Ndufs2 | 8532 | 0.034 | -0.1965 | No |
| 52 | Slc25a12 | 8743 | 0.026 | -0.2068 | No |
| 53 | Idh2 | 8784 | 0.024 | -0.2084 | No |
| 54 | Rhot1 | 8821 | 0.023 | -0.2097 | No |
| 55 | Mrpl15 | 8952 | 0.017 | -0.2161 | No |
| 56 | Ogdh | 9266 | 0.004 | -0.2322 | No |
| 57 | Timm9 | 9631 | -0.006 | -0.2509 | No |
| 58 | Abcb7 | 9663 | -0.008 | -0.2523 | No |
| 59 | Ndufs3 | 9718 | -0.010 | -0.2549 | No |
| 60 | Mtrf1 | 9774 | -0.012 | -0.2575 | No |
| 61 | Ndufa5 | 9907 | -0.017 | -0.2640 | No |
| 62 | Ndufs1 | 9961 | -0.020 | -0.2663 | No |
| 63 | Aco2 | 10004 | -0.022 | -0.2680 | No |
| 64 | Cyb5a | 10047 | -0.023 | -0.2697 | No |
| 65 | Ndufs4 | 10060 | -0.024 | -0.2698 | No |
| 66 | Atp6ap1 | 10199 | -0.029 | -0.2763 | No |
| 67 | Acadm | 10242 | -0.031 | -0.2779 | No |
| 68 | Cox17 | 10302 | -0.033 | -0.2802 | No |
| 69 | Htra2 | 10374 | -0.036 | -0.2831 | No |
| 70 | Cyc1 | 10375 | -0.036 | -0.2823 | No |
| 71 | Uqcrb | 10377 | -0.036 | -0.2816 | No |
| 72 | Acadsb | 10430 | -0.038 | -0.2835 | No |
| 73 | Mgst3 | 10645 | -0.046 | -0.2936 | No |
| 74 | Mrps11 | 10669 | -0.047 | -0.2938 | No |
| 75 | Cs | 10873 | -0.055 | -0.3031 | No |
| 76 | Ndufa8 | 10900 | -0.056 | -0.3033 | No |
| 77 | Glud1 | 10966 | -0.059 | -0.3054 | No |
| 78 | Fdx1 | 11118 | -0.065 | -0.3118 | No |
| 79 | Atp6v0e | 11138 | -0.066 | -0.3114 | No |
| 80 | Sdha | 11243 | -0.071 | -0.3152 | No |
| 81 | Bax | 11381 | -0.077 | -0.3207 | No |
| 82 | Retsat | 11388 | -0.077 | -0.3194 | No |
| 83 | Mdh2 | 11450 | -0.080 | -0.3208 | No |
| 84 | Ndufs8 | 11597 | -0.085 | -0.3266 | No |
| 85 | Rhot2 | 11837 | -0.096 | -0.3369 | No |
| 86 | Echs1 | 11890 | -0.098 | -0.3375 | No |
| 87 | Ech1 | 12036 | -0.104 | -0.3428 | No |
| 88 | Cox5b | 12119 | -0.107 | -0.3447 | No |
| 89 | Nqo2 | 12147 | -0.109 | -0.3438 | No |
| 90 | Aifm1 | 12227 | -0.113 | -0.3455 | No |
| 91 | Idh1 | 12298 | -0.116 | -0.3466 | No |
| 92 | Phb2 | 12542 | -0.129 | -0.3565 | No |
| 93 | Hccs | 12586 | -0.131 | -0.3559 | No |
| 94 | Ndufa9 | 12640 | -0.133 | -0.3558 | No |
| 95 | Uqcr11 | 12843 | -0.140 | -0.3633 | No |
| 96 | Acat1 | 13047 | -0.149 | -0.3706 | No |
| 97 | Ldhb | 13075 | -0.151 | -0.3688 | No |
| 98 | Sdhd | 13179 | -0.156 | -0.3708 | No |
| 99 | Idh3g | 13240 | -0.159 | -0.3705 | No |
| 100 | Supv3l1 | 13400 | -0.167 | -0.3751 | No |
| 101 | Ndufb6 | 13429 | -0.169 | -0.3730 | No |
| 102 | Pdhb | 13539 | -0.173 | -0.3749 | No |
| 103 | Maob | 13700 | -0.180 | -0.3794 | No |
| 104 | Ndufab1 | 13744 | -0.181 | -0.3778 | No |
| 105 | Cox7a2l | 13810 | -0.184 | -0.3772 | No |
| 106 | Aldh6a1 | 13968 | -0.192 | -0.3812 | No |
| 107 | Ndufc1 | 13984 | -0.192 | -0.3779 | No |
| 108 | Sdhb | 14100 | -0.198 | -0.3796 | No |
| 109 | Etfdh | 14118 | -0.199 | -0.3763 | No |
| 110 | Tomm22 | 14363 | -0.210 | -0.3844 | No |
| 111 | Cox11 | 14422 | -0.213 | -0.3829 | No |
| 112 | Ndufb7 | 14517 | -0.218 | -0.3831 | No |
| 113 | Ndufs6 | 14644 | -0.223 | -0.3849 | No |
| 114 | Hadha | 14764 | -0.229 | -0.3861 | No |
| 115 | Ndufb2 | 14789 | -0.230 | -0.3825 | No |
| 116 | Uqcr10 | 15155 | -0.250 | -0.3960 | No |
| 117 | Oxa1l | 15320 | -0.259 | -0.3990 | Yes |
| 118 | Iscu | 15348 | -0.261 | -0.3948 | Yes |
| 119 | Mrps30 | 15421 | -0.265 | -0.3929 | Yes |
| 120 | Grpel1 | 15436 | -0.266 | -0.3880 | Yes |
| 121 | Timm10 | 15483 | -0.270 | -0.3846 | Yes |
| 122 | Hsd17b10 | 15548 | -0.274 | -0.3821 | Yes |
| 123 | Acaa2 | 15568 | -0.275 | -0.3772 | Yes |
| 124 | Timm13 | 15622 | -0.279 | -0.3740 | Yes |
| 125 | Etfb | 15653 | -0.281 | -0.3696 | Yes |
| 126 | Polr2f | 15666 | -0.282 | -0.3642 | Yes |
| 127 | Pdk4 | 15695 | -0.284 | -0.3596 | Yes |
| 128 | Acadvl | 15774 | -0.289 | -0.3575 | Yes |
| 129 | Atp6v1d | 15807 | -0.290 | -0.3529 | Yes |
| 130 | Casp7 | 15812 | -0.291 | -0.3469 | Yes |
| 131 | Ndufv2 | 15842 | -0.293 | -0.3422 | Yes |
| 132 | Uqcrc1 | 15881 | -0.295 | -0.3379 | Yes |
| 133 | Timm17a | 15933 | -0.298 | -0.3342 | Yes |
| 134 | Bdh2 | 15968 | -0.301 | -0.3295 | Yes |
| 135 | Cpt1a | 16025 | -0.303 | -0.3260 | Yes |
| 136 | Uqcrc2 | 16177 | -0.312 | -0.3271 | Yes |
| 137 | Atp1b1 | 16264 | -0.318 | -0.3248 | Yes |
| 138 | Timm50 | 16274 | -0.319 | -0.3185 | Yes |
| 139 | Ndufv1 | 16328 | -0.322 | -0.3144 | Yes |
| 140 | Timm8b | 16516 | -0.334 | -0.3169 | Yes |
| 141 | Decr1 | 16622 | -0.342 | -0.3151 | Yes |
| 142 | Ndufa4 | 16627 | -0.342 | -0.3080 | Yes |
| 143 | Etfa | 16728 | -0.350 | -0.3057 | Yes |
| 144 | Oat | 16972 | -0.369 | -0.3104 | Yes |
| 145 | Mrpl34 | 16977 | -0.370 | -0.3027 | Yes |
| 146 | Ndufb5 | 17018 | -0.374 | -0.2969 | Yes |
| 147 | Slc25a3 | 17186 | -0.387 | -0.2973 | Yes |
| 148 | Atp6v0b | 17214 | -0.390 | -0.2903 | Yes |
| 149 | Suclg1 | 17503 | -0.414 | -0.2964 | Yes |
| 150 | Atp6v1e1 | 17589 | -0.421 | -0.2918 | Yes |
| 151 | Sdhc | 17711 | -0.433 | -0.2889 | Yes |
| 152 | Slc25a4 | 17861 | -0.451 | -0.2870 | Yes |
| 153 | Uqcrh | 17905 | -0.455 | -0.2795 | Yes |
| 154 | Phyh | 18062 | -0.471 | -0.2775 | Yes |
| 155 | Tcirg1 | 18122 | -0.478 | -0.2704 | Yes |
| 156 | Mdh1 | 18167 | -0.485 | -0.2624 | Yes |
| 157 | Slc25a11 | 18259 | -0.497 | -0.2565 | Yes |
| 158 | Atp5pb | 18326 | -0.511 | -0.2490 | Yes |
| 159 | Surf1 | 18385 | -0.519 | -0.2409 | Yes |
| 160 | Cox6a1 | 18414 | -0.524 | -0.2312 | Yes |
| 161 | Ndufa6 | 18474 | -0.532 | -0.2229 | Yes |
| 162 | Ndufa2 | 18543 | -0.541 | -0.2149 | Yes |
| 163 | Ndufb3 | 18545 | -0.541 | -0.2035 | Yes |
| 164 | Slc25a5 | 18552 | -0.541 | -0.1922 | Yes |
| 165 | Atp6v1f | 18671 | -0.562 | -0.1864 | Yes |
| 166 | Uqcrfs1 | 18746 | -0.575 | -0.1779 | Yes |
| 167 | Ndufa1 | 18792 | -0.584 | -0.1678 | Yes |
| 168 | Bckdha | 18814 | -0.590 | -0.1564 | Yes |
| 169 | Cox4i1 | 18819 | -0.591 | -0.1440 | Yes |
| 170 | Cox6c | 18820 | -0.591 | -0.1314 | Yes |
| 171 | Idh3b | 18825 | -0.592 | -0.1190 | Yes |
| 172 | Cyb5r3 | 18829 | -0.594 | -0.1065 | Yes |
| 173 | Ndufa3 | 18890 | -0.609 | -0.0966 | Yes |
| 174 | Eci1 | 18932 | -0.617 | -0.0856 | Yes |
| 175 | Ldha | 18976 | -0.633 | -0.0743 | Yes |
| 176 | Prdx3 | 19009 | -0.641 | -0.0623 | Yes |
| 177 | Cox8a | 19059 | -0.656 | -0.0509 | Yes |
| 178 | Cox5a | 19196 | -0.709 | -0.0428 | Yes |
| 179 | Ndufb8 | 19411 | -0.871 | -0.0353 | Yes |
| 180 | Ndufc2 | 19432 | -0.901 | -0.0172 | Yes |
| 181 | Cox7b | 19465 | -0.998 | 0.0024 | Yes |

