| Dataset | MPP.MPP_Pheno.cls#Group1_versus_Group4.MPP_Pheno.cls#Group1_versus_Group4_repos |
| Phenotype | MPP_Pheno.cls#Group1_versus_Group4_repos |
| Upregulated in class | 0 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | 0.34184113 |
| Normalized Enrichment Score (NES) | 1.3332002 |
| Nominal p-value | 0.1809145 |
| FDR q-value | 0.28369042 |
| FWER p-Value | 0.793 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Cnot9 | 237 | 0.698 | 0.0017 | Yes |
| 2 | Ipo7 | 322 | 0.649 | 0.0103 | Yes |
| 3 | Chek1 | 339 | 0.642 | 0.0224 | Yes |
| 4 | Dck | 362 | 0.635 | 0.0339 | Yes |
| 5 | Mcm4 | 379 | 0.628 | 0.0457 | Yes |
| 6 | Hnrnpd | 383 | 0.627 | 0.0580 | Yes |
| 7 | Wdr90 | 394 | 0.622 | 0.0700 | Yes |
| 8 | Cdc25a | 532 | 0.584 | 0.0746 | Yes |
| 9 | Mcm2 | 569 | 0.574 | 0.0842 | Yes |
| 10 | Dnmt1 | 652 | 0.554 | 0.0910 | Yes |
| 11 | Hells | 691 | 0.546 | 0.1000 | Yes |
| 12 | Mcm6 | 716 | 0.542 | 0.1096 | Yes |
| 13 | Racgap1 | 737 | 0.538 | 0.1194 | Yes |
| 14 | Mcm5 | 908 | 0.505 | 0.1206 | Yes |
| 15 | Timeless | 917 | 0.503 | 0.1303 | Yes |
| 16 | Wee1 | 938 | 0.499 | 0.1393 | Yes |
| 17 | Lig1 | 943 | 0.497 | 0.1490 | Yes |
| 18 | Rpa1 | 994 | 0.491 | 0.1562 | Yes |
| 19 | Prkdc | 1043 | 0.485 | 0.1635 | Yes |
| 20 | Nop56 | 1207 | 0.461 | 0.1643 | Yes |
| 21 | Atad2 | 1221 | 0.459 | 0.1728 | Yes |
| 22 | Prim2 | 1231 | 0.458 | 0.1815 | Yes |
| 23 | Tk1 | 1233 | 0.457 | 0.1906 | Yes |
| 24 | Ccp110 | 1245 | 0.456 | 0.1991 | Yes |
| 25 | Msh2 | 1408 | 0.437 | 0.1995 | Yes |
| 26 | Slbp | 1499 | 0.427 | 0.2034 | Yes |
| 27 | Pold1 | 1545 | 0.424 | 0.2096 | Yes |
| 28 | Shmt1 | 1560 | 0.422 | 0.2173 | Yes |
| 29 | Bard1 | 1641 | 0.413 | 0.2214 | Yes |
| 30 | Smc1a | 1651 | 0.411 | 0.2292 | Yes |
| 31 | Smc3 | 1692 | 0.407 | 0.2352 | Yes |
| 32 | Tacc3 | 1747 | 0.402 | 0.2405 | Yes |
| 33 | Mcm3 | 1808 | 0.396 | 0.2453 | Yes |
| 34 | Ubr7 | 1878 | 0.390 | 0.2495 | Yes |
| 35 | Nasp | 1905 | 0.388 | 0.2560 | Yes |
| 36 | Mre11a | 1979 | 0.381 | 0.2598 | Yes |
| 37 | Ung | 2072 | 0.372 | 0.2625 | Yes |
| 38 | Lmnb1 | 2086 | 0.369 | 0.2692 | Yes |
| 39 | Cdkn2a | 2103 | 0.368 | 0.2757 | Yes |
| 40 | Syncrip | 2110 | 0.368 | 0.2828 | Yes |
| 41 | Gspt1 | 2315 | 0.352 | 0.2793 | Yes |
| 42 | Trip13 | 2333 | 0.350 | 0.2854 | Yes |
| 43 | Brca1 | 2359 | 0.348 | 0.2911 | Yes |
| 44 | Psmc3ip | 2364 | 0.348 | 0.2978 | Yes |
| 45 | Mybl2 | 2448 | 0.341 | 0.3004 | Yes |
| 46 | Xpo1 | 2528 | 0.333 | 0.3029 | Yes |
| 47 | Cdkn2c | 2529 | 0.333 | 0.3096 | Yes |
| 48 | Pole | 2841 | 0.313 | 0.2998 | Yes |
| 49 | Rbbp7 | 2855 | 0.312 | 0.3054 | Yes |
| 50 | Ilf3 | 3049 | 0.301 | 0.3014 | Yes |
| 51 | Rfc1 | 3190 | 0.293 | 0.3000 | Yes |
| 52 | Tcf19 | 3346 | 0.282 | 0.2976 | Yes |
| 53 | Cse1l | 3563 | 0.267 | 0.2918 | Yes |
| 54 | Rad21 | 3630 | 0.262 | 0.2936 | Yes |
| 55 | Xrcc6 | 3706 | 0.257 | 0.2949 | Yes |
| 56 | Ssrp1 | 3738 | 0.255 | 0.2984 | Yes |
| 57 | E2f8 | 3758 | 0.254 | 0.3025 | Yes |
| 58 | Cbx5 | 3784 | 0.251 | 0.3062 | Yes |
| 59 | Stmn1 | 3954 | 0.241 | 0.3023 | Yes |
| 60 | Tmpo | 4022 | 0.236 | 0.3035 | Yes |
| 61 | Pold2 | 4190 | 0.229 | 0.2995 | Yes |
| 62 | Nolc1 | 4221 | 0.227 | 0.3025 | Yes |
| 63 | Ncapd2 | 4276 | 0.223 | 0.3041 | Yes |
| 64 | Pcna | 4308 | 0.221 | 0.3070 | Yes |
| 65 | Spc25 | 4309 | 0.221 | 0.3114 | Yes |
| 66 | Spc24 | 4399 | 0.217 | 0.3111 | Yes |
| 67 | Aurkb | 4481 | 0.212 | 0.3112 | Yes |
| 68 | Dut | 4506 | 0.211 | 0.3142 | Yes |
| 69 | Diaph3 | 4590 | 0.207 | 0.3140 | Yes |
| 70 | Rad51ap1 | 4641 | 0.205 | 0.3155 | Yes |
| 71 | Nbn | 4670 | 0.204 | 0.3182 | Yes |
| 72 | Srsf2 | 4671 | 0.204 | 0.3223 | Yes |
| 73 | Nap1l1 | 4679 | 0.203 | 0.3260 | Yes |
| 74 | Rad50 | 4698 | 0.203 | 0.3291 | Yes |
| 75 | Ak2 | 4739 | 0.201 | 0.3310 | Yes |
| 76 | Pnn | 4822 | 0.197 | 0.3307 | Yes |
| 77 | Nup205 | 4850 | 0.195 | 0.3332 | Yes |
| 78 | Tubb5 | 4886 | 0.193 | 0.3353 | Yes |
| 79 | Suv39h1 | 4897 | 0.192 | 0.3386 | Yes |
| 80 | Brms1l | 4910 | 0.192 | 0.3418 | Yes |
| 81 | Srsf1 | 5023 | 0.186 | 0.3398 | No |
| 82 | Tfrc | 5281 | 0.176 | 0.3300 | No |
| 83 | Ctcf | 5376 | 0.171 | 0.3285 | No |
| 84 | Tra2b | 5404 | 0.169 | 0.3305 | No |
| 85 | Exosc8 | 5406 | 0.169 | 0.3339 | No |
| 86 | Lbr | 5448 | 0.167 | 0.3351 | No |
| 87 | Cks1b | 5579 | 0.161 | 0.3316 | No |
| 88 | Mxd3 | 5601 | 0.160 | 0.3337 | No |
| 89 | Pds5b | 5645 | 0.158 | 0.3346 | No |
| 90 | Tbrg4 | 5656 | 0.158 | 0.3373 | No |
| 91 | Eed | 5778 | 0.151 | 0.3340 | No |
| 92 | Top2a | 5902 | 0.145 | 0.3306 | No |
| 93 | Ube2t | 6121 | 0.135 | 0.3220 | No |
| 94 | Spag5 | 6153 | 0.133 | 0.3230 | No |
| 95 | Hmga1b | 6209 | 0.130 | 0.3228 | No |
| 96 | Ddx39a | 6307 | 0.126 | 0.3203 | No |
| 97 | Eif2s1 | 6354 | 0.123 | 0.3204 | No |
| 98 | Mms22l | 6355 | 0.123 | 0.3228 | No |
| 99 | Pms2 | 6397 | 0.121 | 0.3231 | No |
| 100 | Gins1 | 6406 | 0.120 | 0.3251 | No |
| 101 | Cdca8 | 6486 | 0.117 | 0.3234 | No |
| 102 | Bub1b | 6508 | 0.116 | 0.3246 | No |
| 103 | Ezh2 | 6633 | 0.114 | 0.3205 | No |
| 104 | Asf1a | 6820 | 0.107 | 0.3130 | No |
| 105 | Dclre1b | 6826 | 0.106 | 0.3148 | No |
| 106 | Pola2 | 6878 | 0.105 | 0.3143 | No |
| 107 | Mcm7 | 6972 | 0.100 | 0.3115 | No |
| 108 | Usp1 | 7086 | 0.095 | 0.3075 | No |
| 109 | Anp32e | 7297 | 0.087 | 0.2984 | No |
| 110 | Plk4 | 7386 | 0.083 | 0.2955 | No |
| 111 | Ppp1r8 | 7461 | 0.080 | 0.2933 | No |
| 112 | Brca2 | 7504 | 0.078 | 0.2927 | No |
| 113 | Dek | 7561 | 0.076 | 0.2913 | No |
| 114 | Donson | 7778 | 0.065 | 0.2814 | No |
| 115 | Mlh1 | 8087 | 0.053 | 0.2665 | No |
| 116 | Espl1 | 8142 | 0.050 | 0.2647 | No |
| 117 | Nup153 | 8380 | 0.041 | 0.2533 | No |
| 118 | Psip1 | 8513 | 0.035 | 0.2471 | No |
| 119 | H2az1 | 8753 | 0.025 | 0.2353 | No |
| 120 | Cdca3 | 8832 | 0.022 | 0.2317 | No |
| 121 | Rpa3 | 8838 | 0.022 | 0.2319 | No |
| 122 | Myc | 8957 | 0.017 | 0.2261 | No |
| 123 | Gins4 | 9124 | 0.010 | 0.2177 | No |
| 124 | Prdx4 | 9648 | -0.007 | 0.1908 | No |
| 125 | Smc6 | 9664 | -0.008 | 0.1901 | No |
| 126 | Kif22 | 9726 | -0.010 | 0.1872 | No |
| 127 | Phf5a | 9740 | -0.010 | 0.1867 | No |
| 128 | Nup107 | 9749 | -0.011 | 0.1865 | No |
| 129 | Zw10 | 9882 | -0.016 | 0.1800 | No |
| 130 | Ccne1 | 9998 | -0.021 | 0.1745 | No |
| 131 | Cdk1 | 10065 | -0.024 | 0.1715 | No |
| 132 | Hmmr | 10073 | -0.024 | 0.1716 | No |
| 133 | Hmgb2 | 10108 | -0.025 | 0.1704 | No |
| 134 | Prps1 | 10120 | -0.026 | 0.1703 | No |
| 135 | Chek2 | 10123 | -0.026 | 0.1707 | No |
| 136 | Mad2l1 | 10243 | -0.031 | 0.1652 | No |
| 137 | Jpt1 | 10305 | -0.033 | 0.1627 | No |
| 138 | Cdkn1a | 10760 | -0.050 | 0.1402 | No |
| 139 | Paics | 10796 | -0.052 | 0.1394 | No |
| 140 | Stag1 | 10911 | -0.057 | 0.1347 | No |
| 141 | Rad51c | 10918 | -0.057 | 0.1355 | No |
| 142 | Tipin | 11256 | -0.071 | 0.1195 | No |
| 143 | Kif2c | 11271 | -0.072 | 0.1202 | No |
| 144 | Rfc2 | 11283 | -0.073 | 0.1211 | No |
| 145 | Melk | 11344 | -0.075 | 0.1195 | No |
| 146 | Cit | 11661 | -0.087 | 0.1049 | No |
| 147 | Pold3 | 11715 | -0.091 | 0.1039 | No |
| 148 | Dctpp1 | 11739 | -0.091 | 0.1046 | No |
| 149 | Rfc3 | 11893 | -0.098 | 0.0986 | No |
| 150 | Gins3 | 11932 | -0.100 | 0.0986 | No |
| 151 | Hus1 | 12062 | -0.105 | 0.0941 | No |
| 152 | Luc7l3 | 12092 | -0.106 | 0.0947 | No |
| 153 | Nudt21 | 12157 | -0.109 | 0.0936 | No |
| 154 | Hmgb3 | 12271 | -0.115 | 0.0900 | No |
| 155 | Cenpe | 12284 | -0.116 | 0.0917 | No |
| 156 | Cenpm | 12342 | -0.118 | 0.0911 | No |
| 157 | Lyar | 12389 | -0.121 | 0.0912 | No |
| 158 | Kif4 | 12505 | -0.127 | 0.0878 | No |
| 159 | Birc5 | 12943 | -0.144 | 0.0680 | No |
| 160 | Trp53 | 13271 | -0.161 | 0.0543 | No |
| 161 | Cdc25b | 13398 | -0.167 | 0.0511 | No |
| 162 | Pole4 | 13399 | -0.167 | 0.0545 | No |
| 163 | Orc6 | 13504 | -0.171 | 0.0525 | No |
| 164 | Smc4 | 13563 | -0.174 | 0.0530 | No |
| 165 | Orc2 | 13564 | -0.174 | 0.0565 | No |
| 166 | Mki67 | 13907 | -0.189 | 0.0426 | No |
| 167 | Pa2g4 | 14286 | -0.206 | 0.0271 | No |
| 168 | Cks2 | 14308 | -0.208 | 0.0302 | No |
| 169 | Tubg1 | 14459 | -0.215 | 0.0268 | No |
| 170 | Ube2s | 14474 | -0.216 | 0.0304 | No |
| 171 | Cdc20 | 14986 | -0.240 | 0.0087 | No |
| 172 | Cdkn1b | 15333 | -0.259 | -0.0040 | No |
| 173 | Pan2 | 15498 | -0.271 | -0.0071 | No |
| 174 | Ing3 | 15550 | -0.274 | -0.0042 | No |
| 175 | Dscc1 | 15554 | -0.274 | 0.0011 | No |
| 176 | Dlgap5 | 15662 | -0.281 | 0.0012 | No |
| 177 | Depdc1a | 15763 | -0.288 | 0.0018 | No |
| 178 | Aurka | 15967 | -0.301 | -0.0027 | No |
| 179 | Rpa2 | 16070 | -0.306 | -0.0019 | No |
| 180 | Ran | 16100 | -0.308 | 0.0028 | No |
| 181 | Plk1 | 16141 | -0.309 | 0.0069 | No |
| 182 | Pttg1 | 16186 | -0.313 | 0.0109 | No |
| 183 | Ranbp1 | 16300 | -0.320 | 0.0115 | No |
| 184 | Lsm8 | 17004 | -0.373 | -0.0175 | No |
| 185 | Rnaseh2a | 17039 | -0.376 | -0.0117 | No |
| 186 | Kif18b | 17265 | -0.393 | -0.0155 | No |
| 187 | Mthfd2 | 17266 | -0.393 | -0.0076 | No |
| 188 | Ccnb2 | 17277 | -0.395 | -0.0002 | No |
| 189 | H2ax | 17337 | -0.400 | 0.0047 | No |
| 190 | Ppm1d | 17622 | -0.425 | -0.0015 | No |
| 191 | Cdk4 | 18083 | -0.474 | -0.0158 | No |
| 192 | Rad1 | 18182 | -0.487 | -0.0111 | No |
| 193 | Rrm2 | 18292 | -0.503 | -0.0067 | No |
| 194 | Snrpb | 18368 | -0.518 | -0.0002 | No |
| 195 | Nme1 | 18488 | -0.534 | 0.0043 | No |
| 196 | Asf1b | 18857 | -0.599 | -0.0027 | No |
| 197 | Pop7 | 19286 | -0.761 | -0.0097 | No |
| 198 | Cdkn3 | 19489 | -1.064 | 0.0012 | No |

