| Dataset | MPP.MPP_Pheno.cls#Group1_versus_Group4.MPP_Pheno.cls#Group1_versus_Group4_repos |
| Phenotype | MPP_Pheno.cls#Group1_versus_Group4_repos |
| Upregulated in class | 3 |
| GeneSet | HALLMARK_ALLOGRAFT_REJECTION |
| Enrichment Score (ES) | -0.28517905 |
| Normalized Enrichment Score (NES) | -1.2377534 |
| Nominal p-value | 0.15473887 |
| FDR q-value | 0.6763485 |
| FWER p-Value | 0.936 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Lif | 131 | 0.771 | 0.0132 | No |
| 2 | Akt1 | 153 | 0.752 | 0.0317 | No |
| 3 | Cd4 | 596 | 0.565 | 0.0235 | No |
| 4 | Cd247 | 617 | 0.561 | 0.0370 | No |
| 5 | Prkcb | 645 | 0.556 | 0.0500 | No |
| 6 | Ccr1 | 745 | 0.536 | 0.0588 | No |
| 7 | Hif1a | 1059 | 0.482 | 0.0551 | No |
| 8 | Irf8 | 1298 | 0.449 | 0.0545 | No |
| 9 | Traf2 | 1417 | 0.435 | 0.0597 | No |
| 10 | Cd80 | 1691 | 0.407 | 0.0561 | No |
| 11 | Cd28 | 1832 | 0.395 | 0.0591 | No |
| 12 | Eif3a | 1859 | 0.392 | 0.0680 | No |
| 13 | Itgal | 1961 | 0.383 | 0.0727 | No |
| 14 | Abce1 | 2019 | 0.377 | 0.0795 | No |
| 15 | Cdkn2a | 2103 | 0.368 | 0.0847 | No |
| 16 | Wars1 | 2240 | 0.358 | 0.0870 | No |
| 17 | Hcls1 | 2305 | 0.353 | 0.0928 | No |
| 18 | Brca1 | 2359 | 0.348 | 0.0991 | No |
| 19 | Flna | 2687 | 0.321 | 0.0906 | No |
| 20 | Mrpl3 | 3544 | 0.268 | 0.0533 | No |
| 21 | Crtam | 3583 | 0.266 | 0.0582 | No |
| 22 | Tlr2 | 3763 | 0.253 | 0.0556 | No |
| 23 | Il10 | 3829 | 0.249 | 0.0587 | No |
| 24 | Hdac9 | 4128 | 0.233 | 0.0493 | No |
| 25 | Il16 | 4166 | 0.231 | 0.0534 | No |
| 26 | Itk | 4532 | 0.210 | 0.0400 | No |
| 27 | Igsf6 | 4693 | 0.203 | 0.0370 | No |
| 28 | Zap70 | 4714 | 0.202 | 0.0412 | No |
| 29 | Fgr | 4857 | 0.195 | 0.0389 | No |
| 30 | Fas | 5015 | 0.186 | 0.0356 | No |
| 31 | Acvr2a | 5021 | 0.186 | 0.0402 | No |
| 32 | Ets1 | 5337 | 0.173 | 0.0284 | No |
| 33 | Galnt1 | 5342 | 0.173 | 0.0327 | No |
| 34 | Tgfb2 | 5510 | 0.164 | 0.0283 | No |
| 35 | Degs1 | 5540 | 0.163 | 0.0310 | No |
| 36 | Eif4g3 | 5655 | 0.158 | 0.0292 | No |
| 37 | Il11 | 5966 | 0.142 | 0.0169 | No |
| 38 | Ube2n | 6008 | 0.141 | 0.0184 | No |
| 39 | Tpd52 | 6173 | 0.132 | 0.0134 | No |
| 40 | Ly75 | 6460 | 0.118 | 0.0017 | No |
| 41 | Cd79a | 6537 | 0.115 | 0.0007 | No |
| 42 | Nlrp3 | 6797 | 0.108 | -0.0099 | No |
| 43 | Ccnd2 | 6856 | 0.106 | -0.0101 | No |
| 44 | Socs5 | 6949 | 0.101 | -0.0122 | No |
| 45 | Il12rb1 | 6999 | 0.099 | -0.0122 | No |
| 46 | Stat1 | 7194 | 0.091 | -0.0199 | No |
| 47 | Jak2 | 7272 | 0.088 | -0.0215 | No |
| 48 | Map3k7 | 7415 | 0.082 | -0.0268 | No |
| 49 | Eif3j1 | 7500 | 0.078 | -0.0291 | No |
| 50 | Icam1 | 7740 | 0.066 | -0.0397 | No |
| 51 | Ccr5 | 7909 | 0.059 | -0.0468 | No |
| 52 | Nck1 | 8256 | 0.046 | -0.0635 | No |
| 53 | Stab1 | 8713 | 0.027 | -0.0864 | No |
| 54 | Glmn | 8766 | 0.025 | -0.0884 | No |
| 55 | F2r | 8927 | 0.018 | -0.0962 | No |
| 56 | Abi1 | 9036 | 0.014 | -0.1014 | No |
| 57 | St8sia4 | 9215 | 0.006 | -0.1104 | No |
| 58 | Tap2 | 9253 | 0.005 | -0.1122 | No |
| 59 | Cfp | 9286 | 0.003 | -0.1138 | No |
| 60 | Gcnt1 | 9347 | 0.001 | -0.1169 | No |
| 61 | H2-Aa | 9439 | -0.000 | -0.1216 | No |
| 62 | Elane | 9459 | -0.001 | -0.1225 | No |
| 63 | Tlr1 | 9499 | -0.002 | -0.1245 | No |
| 64 | Fcgr2b | 9732 | -0.010 | -0.1362 | No |
| 65 | Irf4 | 9938 | -0.018 | -0.1463 | No |
| 66 | Ptprc | 10044 | -0.023 | -0.1511 | No |
| 67 | Il18rap | 10218 | -0.030 | -0.1593 | No |
| 68 | Csk | 10278 | -0.032 | -0.1615 | No |
| 69 | Prkcg | 10432 | -0.038 | -0.1684 | No |
| 70 | Il27ra | 10863 | -0.055 | -0.1892 | No |
| 71 | Bcat1 | 11286 | -0.073 | -0.2091 | No |
| 72 | Ikbkb | 11508 | -0.082 | -0.2184 | No |
| 73 | Il2 | 11536 | -0.083 | -0.2176 | No |
| 74 | Stat4 | 11634 | -0.086 | -0.2204 | No |
| 75 | Ifngr1 | 11666 | -0.088 | -0.2197 | No |
| 76 | Il12a | 11700 | -0.090 | -0.2191 | No |
| 77 | Ptpn6 | 11855 | -0.096 | -0.2246 | No |
| 78 | Cd96 | 12158 | -0.109 | -0.2373 | No |
| 79 | Mtif2 | 12160 | -0.109 | -0.2346 | No |
| 80 | Cd47 | 12256 | -0.114 | -0.2365 | No |
| 81 | Lck | 12511 | -0.127 | -0.2463 | No |
| 82 | Ccr2 | 12560 | -0.130 | -0.2454 | No |
| 83 | Ly86 | 12610 | -0.132 | -0.2445 | No |
| 84 | Ripk2 | 12713 | -0.137 | -0.2462 | No |
| 85 | Map4k1 | 12808 | -0.139 | -0.2475 | No |
| 86 | Srgn | 12898 | -0.142 | -0.2484 | No |
| 87 | Tlr6 | 13158 | -0.156 | -0.2577 | No |
| 88 | Npm1 | 13239 | -0.159 | -0.2577 | No |
| 89 | Gpr65 | 13570 | -0.174 | -0.2703 | No |
| 90 | Ncf4 | 13579 | -0.175 | -0.2661 | No |
| 91 | Icosl | 13666 | -0.179 | -0.2659 | No |
| 92 | Csf1 | 13880 | -0.188 | -0.2721 | No |
| 93 | Cxcr3 | 14135 | -0.200 | -0.2800 | Yes |
| 94 | Lcp2 | 14162 | -0.201 | -0.2761 | Yes |
| 95 | Tapbp | 14297 | -0.207 | -0.2777 | Yes |
| 96 | Il4ra | 14328 | -0.209 | -0.2738 | Yes |
| 97 | C2 | 14347 | -0.209 | -0.2693 | Yes |
| 98 | Il4 | 14480 | -0.216 | -0.2705 | Yes |
| 99 | Tap1 | 14543 | -0.219 | -0.2680 | Yes |
| 100 | Spi1 | 14688 | -0.225 | -0.2697 | Yes |
| 101 | Trat1 | 14851 | -0.233 | -0.2720 | Yes |
| 102 | H2-Ob | 15063 | -0.245 | -0.2765 | Yes |
| 103 | Ccl5 | 15121 | -0.248 | -0.2731 | Yes |
| 104 | Eif3d | 15206 | -0.253 | -0.2708 | Yes |
| 105 | Bcl3 | 15231 | -0.254 | -0.2655 | Yes |
| 106 | Ifngr2 | 15349 | -0.261 | -0.2648 | Yes |
| 107 | Irf7 | 15369 | -0.262 | -0.2590 | Yes |
| 108 | Bcl10 | 15370 | -0.262 | -0.2522 | Yes |
| 109 | Lyn | 15388 | -0.263 | -0.2462 | Yes |
| 110 | Was | 15873 | -0.294 | -0.2636 | Yes |
| 111 | Itgb2 | 16118 | -0.309 | -0.2682 | Yes |
| 112 | Cd40 | 16119 | -0.309 | -0.2602 | Yes |
| 113 | Elf4 | 16252 | -0.317 | -0.2588 | Yes |
| 114 | Il15 | 16299 | -0.320 | -0.2529 | Yes |
| 115 | Tnf | 16741 | -0.351 | -0.2665 | Yes |
| 116 | Il7 | 16776 | -0.353 | -0.2591 | Yes |
| 117 | Il18 | 17114 | -0.382 | -0.2666 | Yes |
| 118 | Tgfb1 | 17218 | -0.390 | -0.2618 | Yes |
| 119 | Ube2d1 | 17256 | -0.393 | -0.2535 | Yes |
| 120 | Socs1 | 17267 | -0.394 | -0.2439 | Yes |
| 121 | Rpl9 | 17371 | -0.403 | -0.2387 | Yes |
| 122 | Ache | 17399 | -0.405 | -0.2296 | Yes |
| 123 | Ctss | 17421 | -0.407 | -0.2202 | Yes |
| 124 | Pf4 | 17553 | -0.417 | -0.2161 | Yes |
| 125 | Psmb10 | 17573 | -0.420 | -0.2062 | Yes |
| 126 | H2-DMa | 17575 | -0.420 | -0.1953 | Yes |
| 127 | Ifnar2 | 17678 | -0.429 | -0.1895 | Yes |
| 128 | Apbb1 | 17725 | -0.435 | -0.1806 | Yes |
| 129 | Eif5a | 17782 | -0.441 | -0.1720 | Yes |
| 130 | Tlr3 | 17821 | -0.445 | -0.1625 | Yes |
| 131 | Cd86 | 17856 | -0.450 | -0.1525 | Yes |
| 132 | H2-DMb2 | 18020 | -0.467 | -0.1489 | Yes |
| 133 | H2-Oa | 18211 | -0.492 | -0.1459 | Yes |
| 134 | Cd74 | 18392 | -0.521 | -0.1417 | Yes |
| 135 | Ccnd3 | 18468 | -0.531 | -0.1318 | Yes |
| 136 | Nme1 | 18488 | -0.534 | -0.1190 | Yes |
| 137 | Rps3a1 | 18492 | -0.534 | -0.1053 | Yes |
| 138 | Dyrk3 | 18535 | -0.540 | -0.0934 | Yes |
| 139 | Thy1 | 18664 | -0.560 | -0.0855 | Yes |
| 140 | Rps9 | 18679 | -0.564 | -0.0716 | Yes |
| 141 | Cd1d2 | 18773 | -0.580 | -0.0614 | Yes |
| 142 | Ltb | 19081 | -0.664 | -0.0600 | Yes |
| 143 | Rpl3l | 19132 | -0.681 | -0.0450 | Yes |
| 144 | Il2rg | 19162 | -0.691 | -0.0285 | Yes |
| 145 | B2m | 19422 | -0.884 | -0.0190 | Yes |
| 146 | Capg | 19438 | -0.910 | 0.0038 | Yes |

