Details for gene set HALLMARK_P53

Table: GSEA Results Summary

Dataset	MPP.MPP_Pheno.cls#Group1_versus_Group3.MPP_Pheno.cls#Group1_versus_Group3_repos
Phenotype	MPP_Pheno.cls#Group1_versus_Group3_repos
Upregulated in class	2
GeneSet	HALLMARK_P53_PATHWAY
Enrichment Score (ES)	-0.21174298
Normalized Enrichment Score (NES)	-1.0345439
Nominal p-value	0.3996139
FDR q-value	0.89602476
FWER p-Value	0.996

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Fos	58	0.814	0.0145	No
2	Ctsf	63	0.806	0.0316	No
3	Lif	83	0.771	0.0472	No
4	Ppp1r15a	138	0.713	0.0597	No
5	Hmox1	183	0.679	0.0720	No
6	Rab40c	197	0.671	0.0858	No
7	H2ac25	203	0.668	0.0999	No
8	Zmat3	311	0.613	0.1075	No
9	Btg1	341	0.603	0.1189	No
10	Jun	379	0.591	0.1297	No
11	Coq8a	653	0.513	0.1266	No
12	Aen	713	0.501	0.1343	No
13	Txnip	735	0.496	0.1439	No
14	Prmt2	996	0.456	0.1402	No
15	Ccp110	1023	0.451	0.1486	No
16	Ddit4	1180	0.430	0.1497	No
17	Baiap2	1206	0.428	0.1576	No
18	Abcc5	1607	0.379	0.1451	No
19	Sdc1	1786	0.362	0.1436	No
20	Nudt15	1997	0.344	0.1402	No
21	Trafd1	2033	0.341	0.1457	No
22	Pcna	2239	0.324	0.1420	No
23	Csrnp2	2490	0.308	0.1357	No
24	Tspyl2	2568	0.305	0.1383	No
25	Cdk5r1	2606	0.302	0.1429	No
26	Fam162a	2769	0.291	0.1407	No
27	Sat1	2958	0.277	0.1370	No
28	Hbegf	3105	0.268	0.1352	No
29	Ei24	3231	0.260	0.1343	No
30	Ada	3387	0.251	0.1317	No
31	Ifi30	3466	0.246	0.1329	No
32	Pdgfa	3472	0.246	0.1379	No
33	Vwa5a	3534	0.243	0.1400	No
34	Tsc22d1	3552	0.242	0.1443	No
35	Pidd1	3905	0.225	0.1309	No
36	Tnfsf9	3925	0.224	0.1348	No
37	Sec61a1	3952	0.222	0.1382	No
38	Mdm2	4010	0.219	0.1400	No
39	Perp	4022	0.219	0.1441	No
40	Gls2	4071	0.216	0.1463	No
41	Zbtb16	4344	0.202	0.1365	No
42	Foxo3	4380	0.200	0.1390	No
43	Cyfip2	4419	0.199	0.1413	No
44	Wwp1	4448	0.197	0.1441	No
45	Polh	4608	0.190	0.1400	No
46	Zfp365	4779	0.182	0.1351	No
47	Slc3a2	4780	0.182	0.1390	No
48	Ptpn14	4870	0.178	0.1382	No
49	Klf4	4885	0.177	0.1413	No
50	Steap3	5211	0.164	0.1280	No
51	Apaf1	5362	0.158	0.1236	No
52	Upp1	5520	0.150	0.1187	No
53	Slc35d1	5753	0.138	0.1096	No
54	Elp1	5974	0.128	0.1010	No
55	Sfn	5975	0.128	0.1038	No
56	Dram1	6276	0.116	0.0907	No
57	Ddb2	6380	0.115	0.0879	No
58	Rad9a	6450	0.112	0.0867	No
59	Ninj1	6458	0.111	0.0887	No
60	Ddit3	6471	0.111	0.0905	No
61	Tap1	6559	0.108	0.0883	No
62	Fbxw7	6833	0.095	0.0762	No
63	Trp53	6865	0.094	0.0766	No
64	Kif13b	7055	0.086	0.0687	No
65	Pom121	7106	0.085	0.0680	No
66	Jag2	7178	0.082	0.0660	No
67	Rb1	7269	0.078	0.0631	No
68	Procr	7333	0.076	0.0614	No
69	Notch1	7334	0.076	0.0631	No
70	Ephx1	7526	0.068	0.0546	No
71	Irag2	7588	0.065	0.0529	No
72	Ccnd3	7737	0.059	0.0465	No
73	Hexim1	7795	0.057	0.0448	No
74	Tprkb	7802	0.056	0.0457	No
75	Eps8l2	7942	0.051	0.0396	No
76	Rxra	7992	0.049	0.0381	No
77	Cebpa	8042	0.048	0.0366	No
78	Acvr1b	8139	0.045	0.0326	No
79	Pmm1	8152	0.044	0.0329	No
80	Vdr	8186	0.043	0.0321	No
81	Mapkapk3	8210	0.042	0.0318	No
82	F2r	8437	0.033	0.0208	No
83	Hspa4l	8509	0.029	0.0178	No
84	Ccnd2	8574	0.027	0.0150	No
85	Btg2	8818	0.019	0.0029	No
86	Tax1bp3	8858	0.017	0.0012	No
87	S100a4	8885	0.016	0.0002	No
88	Cdkn2aip	8889	0.016	0.0004	No
89	Sp1	8909	0.015	-0.0002	No
90	Slc7a11	9110	0.008	-0.0104	No
91	Ak1	9120	0.008	-0.0107	No
92	Cdkn2a	9130	0.007	-0.0110	No
93	Blcap	9542	-0.007	-0.0321	No
94	Traf4	9722	-0.014	-0.0411	No
95	Sertad3	10157	-0.030	-0.0629	No
96	Nol8	10583	-0.047	-0.0839	No
97	Abhd4	10713	-0.052	-0.0895	No
98	Ccng1	10755	-0.053	-0.0904	No
99	St14	10780	-0.054	-0.0905	No
100	Rap2b	10864	-0.058	-0.0936	No
101	Stom	11011	-0.064	-0.0997	No
102	Cdh13	11057	-0.067	-0.1006	No
103	Atf3	11177	-0.071	-0.1053	No
104	Ptpre	11200	-0.072	-0.1049	No
105	Ercc5	11270	-0.075	-0.1068	No
106	Fas	11413	-0.079	-0.1125	No
107	App	11456	-0.080	-0.1129	No
108	Irak1	11489	-0.081	-0.1128	No
109	Cd82	11553	-0.085	-0.1143	No
110	Rad51c	11673	-0.089	-0.1185	No
111	Hdac3	11793	-0.093	-0.1227	No
112	Mknk2	11803	-0.093	-0.1211	No
113	Prkab1	11876	-0.097	-0.1228	No
114	Bax	11886	-0.097	-0.1212	No
115	Fdxr	11894	-0.097	-0.1194	No
116	Pvt1	11986	-0.101	-0.1220	No
117	Ip6k2	12047	-0.103	-0.1229	No
118	Epha2	12431	-0.120	-0.1401	No
119	Rrp8	12478	-0.121	-0.1399	No
120	Ralgds	12562	-0.124	-0.1415	No
121	Plk3	12586	-0.125	-0.1400	No
122	Cgrrf1	12785	-0.135	-0.1473	No
123	Zfp36l1	12954	-0.142	-0.1530	No
124	H2aj	13011	-0.145	-0.1528	No
125	Rchy1	13015	-0.145	-0.1498	No
126	Rhbdf2	13077	-0.148	-0.1498	No
127	S100a10	13159	-0.150	-0.1508	No
128	Cdkn1a	13574	-0.170	-0.1685	No
129	Sesn1	13623	-0.172	-0.1673	No
130	Tob1	13632	-0.173	-0.1640	No
131	Def6	13746	-0.179	-0.1660	No
132	Dnttip2	13802	-0.181	-0.1650	No
133	Rps12	13821	-0.182	-0.1620	No
134	Dgka	13864	-0.184	-0.1602	No
135	Xpc	13935	-0.187	-0.1598	No
136	Hras	14049	-0.193	-0.1615	No
137	Trp63	14170	-0.199	-0.1634	No
138	H1f2	14519	-0.215	-0.1768	No
139	Ctsd	14754	-0.225	-0.1841	No
140	Bak1	14796	-0.228	-0.1813	No
141	Mxd4	14887	-0.233	-0.1810	No
142	Ccnk	14895	-0.234	-0.1763	No
143	Socs1	14993	-0.240	-0.1762	No
144	Ldhb	15681	-0.277	-0.2058	Yes
145	Tcn2	15781	-0.282	-0.2048	Yes
146	Pitpnc1	15816	-0.284	-0.2005	Yes
147	Rrad	15843	-0.285	-0.1957	Yes
148	Casp1	15896	-0.289	-0.1922	Yes
149	Osgin1	15976	-0.294	-0.1900	Yes
150	Itgb4	16175	-0.307	-0.1936	Yes
151	Plxnb2	16292	-0.315	-0.1929	Yes
152	Ppm1d	16369	-0.320	-0.1899	Yes
153	Rnf19b	16379	-0.321	-0.1835	Yes
154	Vamp8	16395	-0.322	-0.1773	Yes
155	Wrap73	16398	-0.323	-0.1705	Yes
156	Fuca1	16433	-0.326	-0.1652	Yes
157	Iscu	16586	-0.335	-0.1659	Yes
158	Ndrg1	16743	-0.348	-0.1665	Yes
159	Nupr1	16834	-0.353	-0.1636	Yes
160	Trib3	16944	-0.361	-0.1615	Yes
161	Slc19a2	16966	-0.363	-0.1548	Yes
162	Tpd52l1	16986	-0.364	-0.1480	Yes
163	Sphk1	17006	-0.365	-0.1411	Yes
164	Ankra2	17061	-0.369	-0.1360	Yes
165	Triap1	17202	-0.379	-0.1351	Yes
166	Cd81	17285	-0.385	-0.1310	Yes
167	Tm7sf3	17408	-0.396	-0.1289	Yes
168	Rps27l	17581	-0.413	-0.1289	Yes
169	Rpl18	17699	-0.426	-0.1258	Yes
170	Tgfb1	17706	-0.427	-0.1169	Yes
171	Mxd1	17817	-0.439	-0.1132	Yes
172	Alox8	17818	-0.440	-0.1037	Yes
173	Rpl36	18111	-0.472	-0.1087	Yes
174	Abat	18312	-0.499	-0.1083	Yes
175	Fgf13	18314	-0.499	-0.0977	Yes
176	Rack1	18369	-0.508	-0.0895	Yes
177	Ier3	18498	-0.527	-0.0848	Yes
178	Klk8	18578	-0.542	-0.0773	Yes
179	Dcxr	18708	-0.565	-0.0718	Yes
180	Gadd45a	18739	-0.572	-0.0611	Yes
181	Retsat	18743	-0.573	-0.0489	Yes
182	Tgfa	18758	-0.575	-0.0373	Yes
183	Plk2	18801	-0.582	-0.0270	Yes
184	Hint1	18864	-0.598	-0.0173	Yes
185	Ier5	19080	-0.668	-0.0141	Yes
186	Gm2a	19180	-0.705	-0.0041	Yes
187	Phlda3	19461	-0.987	0.0026	Yes