| Dataset | MPP.MPP_Pheno.cls#Group1_versus_Group3.MPP_Pheno.cls#Group1_versus_Group3_repos |
| Phenotype | MPP_Pheno.cls#Group1_versus_Group3_repos |
| Upregulated in class | 2 |
| GeneSet | HALLMARK_OXIDATIVE_PHOSPHORYLATION |
| Enrichment Score (ES) | -0.31118885 |
| Normalized Enrichment Score (NES) | -1.0816904 |
| Nominal p-value | 0.39489195 |
| FDR q-value | 0.9185981 |
| FWER p-Value | 0.993 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Mfn2 | 344 | 0.603 | -0.0016 | No |
| 2 | Lrpprc | 772 | 0.490 | -0.0105 | No |
| 3 | Gpx4 | 1095 | 0.441 | -0.0154 | No |
| 4 | Hspa9 | 1170 | 0.431 | -0.0076 | No |
| 5 | Ndufa5 | 1606 | 0.379 | -0.0199 | No |
| 6 | Mtx2 | 1932 | 0.351 | -0.0273 | No |
| 7 | Gpi1 | 2086 | 0.337 | -0.0262 | No |
| 8 | Por | 2123 | 0.333 | -0.0191 | No |
| 9 | Pdhx | 2129 | 0.333 | -0.0104 | No |
| 10 | Mtrr | 2229 | 0.324 | -0.0068 | No |
| 11 | Atp6v1h | 2345 | 0.317 | -0.0043 | No |
| 12 | Atp6v0c | 2388 | 0.315 | 0.0020 | No |
| 13 | Hadhb | 2658 | 0.298 | -0.0039 | No |
| 14 | Pdha1 | 2760 | 0.292 | -0.0013 | No |
| 15 | Dlst | 2795 | 0.289 | 0.0047 | No |
| 16 | Dlat | 2968 | 0.277 | 0.0033 | No |
| 17 | Mrpl11 | 3074 | 0.270 | 0.0051 | No |
| 18 | Ndufb6 | 3550 | 0.242 | -0.0130 | No |
| 19 | Dld | 3901 | 0.225 | -0.0251 | No |
| 20 | Ndufs3 | 4060 | 0.217 | -0.0274 | No |
| 21 | Vdac3 | 4232 | 0.208 | -0.0307 | No |
| 22 | Cpt1a | 4647 | 0.188 | -0.0471 | No |
| 23 | Sdhd | 4688 | 0.186 | -0.0441 | No |
| 24 | Tomm70a | 4924 | 0.175 | -0.0516 | No |
| 25 | Rhot1 | 5035 | 0.169 | -0.0527 | No |
| 26 | Bdh2 | 5136 | 0.166 | -0.0534 | No |
| 27 | Atp6ap1 | 5559 | 0.148 | -0.0713 | No |
| 28 | Afg3l2 | 5645 | 0.144 | -0.0718 | No |
| 29 | Pmpca | 5650 | 0.143 | -0.0682 | No |
| 30 | Ndufa9 | 5684 | 0.141 | -0.0661 | No |
| 31 | Atp6v0e | 5723 | 0.140 | -0.0643 | No |
| 32 | Fh1 | 5741 | 0.139 | -0.0614 | No |
| 33 | Fxn | 6410 | 0.113 | -0.0930 | No |
| 34 | Nnt | 6460 | 0.111 | -0.0925 | No |
| 35 | Mdh2 | 6571 | 0.108 | -0.0953 | No |
| 36 | Pdhb | 6660 | 0.104 | -0.0971 | No |
| 37 | Mrpl15 | 6668 | 0.104 | -0.0946 | No |
| 38 | Hsd17b10 | 6787 | 0.098 | -0.0981 | No |
| 39 | Timm17a | 7082 | 0.085 | -0.1110 | No |
| 40 | Glud1 | 7098 | 0.085 | -0.1095 | No |
| 41 | Ndufs1 | 7260 | 0.079 | -0.1157 | No |
| 42 | Opa1 | 7332 | 0.076 | -0.1174 | No |
| 43 | Etfdh | 7366 | 0.074 | -0.1171 | No |
| 44 | Slc25a12 | 7397 | 0.073 | -0.1167 | No |
| 45 | Sucla2 | 7442 | 0.071 | -0.1171 | No |
| 46 | Mrps15 | 7453 | 0.070 | -0.1157 | No |
| 47 | Ndufc1 | 7462 | 0.070 | -0.1143 | No |
| 48 | Immt | 7518 | 0.068 | -0.1153 | No |
| 49 | Cox10 | 7768 | 0.058 | -0.1266 | No |
| 50 | Ndufs8 | 8001 | 0.049 | -0.1373 | No |
| 51 | Vdac2 | 8034 | 0.048 | -0.1376 | No |
| 52 | Ech1 | 8247 | 0.040 | -0.1475 | No |
| 53 | Acaa1a | 8268 | 0.039 | -0.1475 | No |
| 54 | Supv3l1 | 8332 | 0.037 | -0.1498 | No |
| 55 | Uqcrq | 8527 | 0.028 | -0.1590 | No |
| 56 | Ndufs6 | 8575 | 0.027 | -0.1608 | No |
| 57 | Mpc1 | 9032 | 0.011 | -0.1841 | No |
| 58 | Cox15 | 9149 | 0.007 | -0.1899 | No |
| 59 | Ndufb5 | 9308 | 0.001 | -0.1980 | No |
| 60 | Timm9 | 9492 | -0.005 | -0.2074 | No |
| 61 | Mtrf1 | 9844 | -0.019 | -0.2250 | No |
| 62 | Acadm | 9890 | -0.021 | -0.2268 | No |
| 63 | Sdha | 10028 | -0.025 | -0.2332 | No |
| 64 | Atp6v1c1 | 10031 | -0.026 | -0.2326 | No |
| 65 | Prdx3 | 10049 | -0.026 | -0.2328 | No |
| 66 | Aco2 | 10120 | -0.029 | -0.2356 | No |
| 67 | Idh3a | 10149 | -0.030 | -0.2363 | No |
| 68 | Uqcr11 | 10232 | -0.034 | -0.2396 | No |
| 69 | Cox6b1 | 10246 | -0.034 | -0.2394 | No |
| 70 | Ndufa7 | 10272 | -0.035 | -0.2397 | No |
| 71 | Aifm1 | 10411 | -0.040 | -0.2458 | No |
| 72 | Cox5b | 10419 | -0.040 | -0.2450 | No |
| 73 | Uqcrc2 | 10438 | -0.041 | -0.2449 | No |
| 74 | Echs1 | 10474 | -0.042 | -0.2456 | No |
| 75 | Mgst3 | 10565 | -0.046 | -0.2490 | No |
| 76 | Cox7a2 | 10585 | -0.047 | -0.2487 | No |
| 77 | Idh2 | 10624 | -0.049 | -0.2493 | No |
| 78 | Got2 | 10628 | -0.049 | -0.2482 | No |
| 79 | Uqcr10 | 10718 | -0.052 | -0.2514 | No |
| 80 | Phyh | 10842 | -0.057 | -0.2562 | No |
| 81 | Phb2 | 10901 | -0.060 | -0.2576 | No |
| 82 | Atp6v0b | 10987 | -0.063 | -0.2603 | No |
| 83 | Timm10 | 11008 | -0.064 | -0.2597 | No |
| 84 | Pdk4 | 11071 | -0.067 | -0.2611 | No |
| 85 | Uqcrb | 11079 | -0.067 | -0.2596 | No |
| 86 | Mrpl34 | 11143 | -0.070 | -0.2610 | No |
| 87 | Mrps12 | 11172 | -0.071 | -0.2605 | No |
| 88 | Pdp1 | 11243 | -0.074 | -0.2622 | No |
| 89 | Cox17 | 11609 | -0.087 | -0.2787 | No |
| 90 | Fdx1 | 11632 | -0.088 | -0.2775 | No |
| 91 | Htra2 | 11698 | -0.090 | -0.2785 | No |
| 92 | Cox7c | 11738 | -0.091 | -0.2780 | No |
| 93 | Atp6v1e1 | 11817 | -0.094 | -0.2795 | No |
| 94 | Bax | 11886 | -0.097 | -0.2804 | No |
| 95 | Mrps22 | 11948 | -0.099 | -0.2809 | No |
| 96 | Ndufs2 | 12059 | -0.104 | -0.2838 | No |
| 97 | Cyb5r3 | 12142 | -0.107 | -0.2852 | No |
| 98 | Ogdh | 12226 | -0.111 | -0.2865 | No |
| 99 | Acadvl | 12304 | -0.114 | -0.2874 | No |
| 100 | Vdac1 | 12317 | -0.115 | -0.2850 | No |
| 101 | Casp7 | 12346 | -0.116 | -0.2833 | No |
| 102 | Etfb | 12361 | -0.116 | -0.2809 | No |
| 103 | Suclg1 | 12422 | -0.119 | -0.2808 | No |
| 104 | Ndufa4 | 12468 | -0.121 | -0.2799 | No |
| 105 | Atp1b1 | 12507 | -0.122 | -0.2785 | No |
| 106 | Oxa1l | 12532 | -0.123 | -0.2765 | No |
| 107 | Ndufv2 | 12545 | -0.124 | -0.2738 | No |
| 108 | Surf1 | 12546 | -0.124 | -0.2704 | No |
| 109 | Hadha | 12568 | -0.125 | -0.2682 | No |
| 110 | Uqcrfs1 | 12732 | -0.132 | -0.2731 | No |
| 111 | Ndufb2 | 12936 | -0.142 | -0.2797 | No |
| 112 | Rhot2 | 13022 | -0.146 | -0.2802 | No |
| 113 | Cox11 | 13280 | -0.156 | -0.2893 | No |
| 114 | Mrpl35 | 13492 | -0.166 | -0.2958 | No |
| 115 | Acat1 | 13557 | -0.169 | -0.2946 | No |
| 116 | Etfa | 13879 | -0.185 | -0.3062 | Yes |
| 117 | Ndufa8 | 13908 | -0.186 | -0.3027 | Yes |
| 118 | Ldha | 14037 | -0.192 | -0.3041 | Yes |
| 119 | Grpel1 | 14093 | -0.195 | -0.3018 | Yes |
| 120 | Abcb7 | 14102 | -0.195 | -0.2969 | Yes |
| 121 | Ndufa6 | 14164 | -0.198 | -0.2948 | Yes |
| 122 | Atp6v1g1 | 14287 | -0.204 | -0.2956 | Yes |
| 123 | Cyb5a | 14348 | -0.207 | -0.2931 | Yes |
| 124 | Cs | 14458 | -0.211 | -0.2931 | Yes |
| 125 | Mrps11 | 14627 | -0.220 | -0.2959 | Yes |
| 126 | Cox4i1 | 14846 | -0.231 | -0.3010 | Yes |
| 127 | Ndufa2 | 14960 | -0.237 | -0.3004 | Yes |
| 128 | Ndufv1 | 14961 | -0.237 | -0.2941 | Yes |
| 129 | Oat | 14974 | -0.238 | -0.2883 | Yes |
| 130 | Ndufs7 | 14984 | -0.239 | -0.2823 | Yes |
| 131 | Atp6v1d | 15008 | -0.240 | -0.2771 | Yes |
| 132 | Slc25a5 | 15087 | -0.245 | -0.2745 | Yes |
| 133 | Cyc1 | 15095 | -0.245 | -0.2683 | Yes |
| 134 | Idh3g | 15363 | -0.260 | -0.2751 | Yes |
| 135 | Bckdha | 15407 | -0.261 | -0.2704 | Yes |
| 136 | Tomm22 | 15472 | -0.266 | -0.2665 | Yes |
| 137 | Polr2f | 15503 | -0.268 | -0.2609 | Yes |
| 138 | Sdhb | 15599 | -0.273 | -0.2585 | Yes |
| 139 | Cox7b | 15651 | -0.275 | -0.2537 | Yes |
| 140 | Ldhb | 15681 | -0.277 | -0.2478 | Yes |
| 141 | Timm13 | 15741 | -0.280 | -0.2433 | Yes |
| 142 | Slc25a20 | 15779 | -0.282 | -0.2376 | Yes |
| 143 | Ndufab1 | 15790 | -0.283 | -0.2306 | Yes |
| 144 | Atp5pb | 15848 | -0.286 | -0.2258 | Yes |
| 145 | Cox6a1 | 15851 | -0.286 | -0.2182 | Yes |
| 146 | Maob | 15980 | -0.294 | -0.2170 | Yes |
| 147 | Ndufb3 | 16027 | -0.297 | -0.2114 | Yes |
| 148 | Alas1 | 16120 | -0.303 | -0.2080 | Yes |
| 149 | Ndufs4 | 16164 | -0.306 | -0.2020 | Yes |
| 150 | Atp6v1f | 16445 | -0.326 | -0.2077 | Yes |
| 151 | Idh1 | 16484 | -0.327 | -0.2009 | Yes |
| 152 | Ndufa3 | 16553 | -0.333 | -0.1955 | Yes |
| 153 | Cox7a2l | 16554 | -0.333 | -0.1866 | Yes |
| 154 | Iscu | 16586 | -0.335 | -0.1792 | Yes |
| 155 | Slc25a4 | 16683 | -0.343 | -0.1749 | Yes |
| 156 | Ndufb7 | 16692 | -0.344 | -0.1661 | Yes |
| 157 | Acaa2 | 16798 | -0.351 | -0.1621 | Yes |
| 158 | Acadsb | 16925 | -0.359 | -0.1590 | Yes |
| 159 | Nqo2 | 16943 | -0.361 | -0.1502 | Yes |
| 160 | Uqcrh | 16964 | -0.362 | -0.1415 | Yes |
| 161 | Timm8b | 17073 | -0.370 | -0.1371 | Yes |
| 162 | Decr1 | 17284 | -0.385 | -0.1377 | Yes |
| 163 | Slc25a3 | 17302 | -0.386 | -0.1282 | Yes |
| 164 | Aldh6a1 | 17381 | -0.393 | -0.1216 | Yes |
| 165 | Hccs | 17607 | -0.416 | -0.1221 | Yes |
| 166 | Slc25a11 | 17683 | -0.424 | -0.1146 | Yes |
| 167 | Tcirg1 | 17749 | -0.431 | -0.1064 | Yes |
| 168 | Cox8a | 17937 | -0.451 | -0.1040 | Yes |
| 169 | Eci1 | 17974 | -0.455 | -0.0936 | Yes |
| 170 | Cox6c | 18142 | -0.478 | -0.0894 | Yes |
| 171 | Ndufa1 | 18203 | -0.484 | -0.0795 | Yes |
| 172 | Ndufb8 | 18223 | -0.487 | -0.0674 | Yes |
| 173 | Idh3b | 18350 | -0.505 | -0.0604 | Yes |
| 174 | Timm50 | 18367 | -0.507 | -0.0476 | Yes |
| 175 | Sdhc | 18475 | -0.522 | -0.0391 | Yes |
| 176 | Uqcrc1 | 18515 | -0.531 | -0.0269 | Yes |
| 177 | Mdh1 | 18525 | -0.533 | -0.0130 | Yes |
| 178 | Cox5a | 18568 | -0.541 | -0.0007 | Yes |
| 179 | Retsat | 18743 | -0.573 | 0.0057 | Yes |
| 180 | Mrps30 | 18847 | -0.594 | 0.0163 | Yes |
| 181 | Ndufc2 | 19084 | -0.671 | 0.0221 | Yes |

