| Dataset | MPP.MPP_Pheno.cls#Group1_versus_Group3.MPP_Pheno.cls#Group1_versus_Group3_repos |
| Phenotype | MPP_Pheno.cls#Group1_versus_Group3_repos |
| Upregulated in class | 2 |
| GeneSet | HALLMARK_MITOTIC_SPINDLE |
| Enrichment Score (ES) | -0.24987666 |
| Normalized Enrichment Score (NES) | -1.1545355 |
| Nominal p-value | 0.3164557 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.982 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Dynll2 | 371 | 0.593 | -0.0066 | No |
| 2 | Arhgef12 | 472 | 0.557 | 0.0000 | No |
| 3 | Rasal2 | 633 | 0.517 | 0.0027 | No |
| 4 | Cep131 | 693 | 0.505 | 0.0104 | No |
| 5 | Numa1 | 694 | 0.504 | 0.0211 | No |
| 6 | Sptan1 | 743 | 0.494 | 0.0291 | No |
| 7 | Lrpprc | 772 | 0.490 | 0.0381 | No |
| 8 | Wasf1 | 787 | 0.488 | 0.0477 | No |
| 9 | Smc1a | 908 | 0.471 | 0.0515 | No |
| 10 | Dync1h1 | 1330 | 0.409 | 0.0384 | No |
| 11 | Arhgap10 | 1567 | 0.383 | 0.0343 | No |
| 12 | Cdc42bpa | 1603 | 0.380 | 0.0406 | No |
| 13 | Trio | 1616 | 0.378 | 0.0480 | No |
| 14 | Rapgef5 | 1674 | 0.372 | 0.0529 | No |
| 15 | Ranbp9 | 2000 | 0.344 | 0.0434 | No |
| 16 | Arhgap5 | 2067 | 0.338 | 0.0472 | No |
| 17 | Smc3 | 2247 | 0.323 | 0.0448 | No |
| 18 | Fgd4 | 2452 | 0.311 | 0.0408 | No |
| 19 | Nck2 | 2497 | 0.307 | 0.0450 | No |
| 20 | Tubgcp6 | 2573 | 0.305 | 0.0476 | No |
| 21 | Dst | 2605 | 0.302 | 0.0524 | No |
| 22 | Kptn | 2617 | 0.301 | 0.0583 | No |
| 23 | Cep250 | 2630 | 0.300 | 0.0640 | No |
| 24 | Palld | 2648 | 0.299 | 0.0695 | No |
| 25 | Abl1 | 2653 | 0.299 | 0.0756 | No |
| 26 | Pcnt | 2727 | 0.294 | 0.0781 | No |
| 27 | Ophn1 | 2773 | 0.291 | 0.0819 | No |
| 28 | Arhgef7 | 2808 | 0.288 | 0.0863 | No |
| 29 | Klc1 | 2859 | 0.284 | 0.0897 | No |
| 30 | Stau1 | 2893 | 0.281 | 0.0940 | No |
| 31 | Prex1 | 2906 | 0.280 | 0.0993 | No |
| 32 | Itsn1 | 3052 | 0.271 | 0.0976 | No |
| 33 | Map1s | 3109 | 0.268 | 0.1004 | No |
| 34 | Notch2 | 3126 | 0.267 | 0.1052 | No |
| 35 | Myh9 | 3187 | 0.262 | 0.1077 | No |
| 36 | Sptbn1 | 3218 | 0.261 | 0.1117 | No |
| 37 | Mid1ip1 | 3311 | 0.254 | 0.1123 | No |
| 38 | Arhgdia | 3400 | 0.250 | 0.1130 | No |
| 39 | Epb41 | 3431 | 0.248 | 0.1168 | No |
| 40 | Tubgcp2 | 3451 | 0.247 | 0.1210 | No |
| 41 | Arfgef1 | 3525 | 0.244 | 0.1224 | No |
| 42 | Wasl | 3570 | 0.241 | 0.1253 | No |
| 43 | Cep192 | 3584 | 0.241 | 0.1297 | No |
| 44 | Ppp4r2 | 4108 | 0.214 | 0.1072 | No |
| 45 | Myo9b | 4172 | 0.210 | 0.1084 | No |
| 46 | Stk38l | 4314 | 0.203 | 0.1054 | No |
| 47 | Fscn1 | 4391 | 0.200 | 0.1057 | No |
| 48 | Nedd9 | 4415 | 0.199 | 0.1087 | No |
| 49 | Rfc1 | 4451 | 0.197 | 0.1111 | No |
| 50 | Lats1 | 4509 | 0.195 | 0.1123 | No |
| 51 | Tbcd | 4702 | 0.185 | 0.1063 | No |
| 52 | Actn4 | 4717 | 0.184 | 0.1095 | No |
| 53 | Clasp1 | 5150 | 0.165 | 0.0906 | No |
| 54 | Flna | 5205 | 0.164 | 0.0913 | No |
| 55 | Hook3 | 5285 | 0.161 | 0.0906 | No |
| 56 | Kntc1 | 5452 | 0.153 | 0.0853 | No |
| 57 | Pcm1 | 5510 | 0.150 | 0.0855 | No |
| 58 | Alms1 | 5577 | 0.147 | 0.0853 | No |
| 59 | Tubgcp3 | 5585 | 0.147 | 0.0880 | No |
| 60 | Cdk5rap2 | 5609 | 0.146 | 0.0899 | No |
| 61 | Rapgef6 | 5612 | 0.145 | 0.0929 | No |
| 62 | Tiam1 | 5632 | 0.145 | 0.0950 | No |
| 63 | Mid1 | 5640 | 0.144 | 0.0977 | No |
| 64 | Bcl2l11 | 5710 | 0.140 | 0.0971 | No |
| 65 | Sun2 | 5908 | 0.131 | 0.0897 | No |
| 66 | Myh10 | 5976 | 0.128 | 0.0889 | No |
| 67 | Rasa1 | 6127 | 0.122 | 0.0838 | No |
| 68 | Pafah1b1 | 6202 | 0.119 | 0.0824 | No |
| 69 | Pkd2 | 6219 | 0.118 | 0.0841 | No |
| 70 | Lmnb1 | 6274 | 0.116 | 0.0838 | No |
| 71 | Ywhae | 6315 | 0.115 | 0.0842 | No |
| 72 | Gemin4 | 6414 | 0.113 | 0.0815 | No |
| 73 | Clip2 | 6444 | 0.112 | 0.0824 | No |
| 74 | Bcr | 6496 | 0.110 | 0.0821 | No |
| 75 | Kif5b | 6514 | 0.110 | 0.0835 | No |
| 76 | Fgd6 | 6674 | 0.103 | 0.0775 | No |
| 77 | Tlk1 | 6754 | 0.099 | 0.0755 | No |
| 78 | Map3k11 | 6764 | 0.099 | 0.0772 | No |
| 79 | Nck1 | 6946 | 0.091 | 0.0697 | No |
| 80 | Arfip2 | 6990 | 0.090 | 0.0694 | No |
| 81 | Kif1b | 7063 | 0.086 | 0.0675 | No |
| 82 | Bin1 | 7116 | 0.084 | 0.0666 | No |
| 83 | Rhof | 7236 | 0.080 | 0.0621 | No |
| 84 | Atg4b | 7264 | 0.079 | 0.0624 | No |
| 85 | Abr | 7284 | 0.078 | 0.0631 | No |
| 86 | Pdlim5 | 7536 | 0.067 | 0.0515 | No |
| 87 | Nin | 7601 | 0.064 | 0.0496 | No |
| 88 | Septin9 | 7724 | 0.060 | 0.0445 | No |
| 89 | Arhgef2 | 7757 | 0.059 | 0.0441 | No |
| 90 | Dlg1 | 7801 | 0.056 | 0.0431 | No |
| 91 | Rab3gap1 | 8032 | 0.048 | 0.0322 | No |
| 92 | Abi1 | 8046 | 0.048 | 0.0325 | No |
| 93 | Sos1 | 8163 | 0.044 | 0.0274 | No |
| 94 | Taok2 | 8225 | 0.041 | 0.0252 | No |
| 95 | Hdac6 | 8284 | 0.039 | 0.0230 | No |
| 96 | Pxn | 8301 | 0.038 | 0.0230 | No |
| 97 | Dock2 | 8506 | 0.029 | 0.0130 | No |
| 98 | Rabgap1 | 8666 | 0.024 | 0.0053 | No |
| 99 | Cd2ap | 8735 | 0.022 | 0.0022 | No |
| 100 | Tsc1 | 8819 | 0.019 | -0.0017 | No |
| 101 | Brca2 | 8848 | 0.017 | -0.0027 | No |
| 102 | Arf6 | 8992 | 0.012 | -0.0099 | No |
| 103 | Arhgap29 | 9094 | 0.009 | -0.0149 | No |
| 104 | Farp1 | 9162 | 0.006 | -0.0183 | No |
| 105 | Cep57 | 9353 | -0.000 | -0.0281 | No |
| 106 | Wasf2 | 9455 | -0.004 | -0.0332 | No |
| 107 | Csnk1d | 9564 | -0.008 | -0.0387 | No |
| 108 | Cyth2 | 9607 | -0.009 | -0.0407 | No |
| 109 | Arhgef11 | 9668 | -0.012 | -0.0435 | No |
| 110 | Katnb1 | 9672 | -0.012 | -0.0434 | No |
| 111 | Ttk | 9786 | -0.016 | -0.0489 | No |
| 112 | Katna1 | 9839 | -0.019 | -0.0512 | No |
| 113 | Epb41l2 | 9853 | -0.019 | -0.0515 | No |
| 114 | Cntrob | 9865 | -0.020 | -0.0516 | No |
| 115 | Fbxo5 | 9966 | -0.023 | -0.0563 | No |
| 116 | Rock1 | 10025 | -0.025 | -0.0588 | No |
| 117 | Cntrl | 10079 | -0.027 | -0.0610 | No |
| 118 | Kifap3 | 10390 | -0.039 | -0.0762 | No |
| 119 | Clip1 | 10837 | -0.056 | -0.0981 | No |
| 120 | Cttn | 10838 | -0.056 | -0.0969 | No |
| 121 | Akap13 | 10865 | -0.058 | -0.0970 | No |
| 122 | Apc | 10892 | -0.059 | -0.0971 | No |
| 123 | Rasa2 | 11042 | -0.066 | -0.1034 | No |
| 124 | Rictor | 11159 | -0.070 | -0.1079 | No |
| 125 | Net1 | 11219 | -0.073 | -0.1094 | No |
| 126 | Kif3c | 11285 | -0.076 | -0.1112 | No |
| 127 | Vcl | 11360 | -0.076 | -0.1134 | No |
| 128 | Nf1 | 11424 | -0.079 | -0.1150 | No |
| 129 | Arhgap4 | 11628 | -0.087 | -0.1236 | No |
| 130 | Cdc42 | 11669 | -0.089 | -0.1238 | No |
| 131 | Ssh2 | 11684 | -0.089 | -0.1226 | No |
| 132 | Mark4 | 11690 | -0.090 | -0.1210 | No |
| 133 | Ccdc88a | 11918 | -0.098 | -0.1306 | No |
| 134 | Plekhg2 | 11927 | -0.099 | -0.1290 | No |
| 135 | Incenp | 12633 | -0.128 | -0.1627 | No |
| 136 | Pcgf5 | 12837 | -0.137 | -0.1703 | No |
| 137 | Rhot2 | 13022 | -0.146 | -0.1768 | No |
| 138 | Sac3d1 | 13032 | -0.146 | -0.1741 | No |
| 139 | Mapre1 | 13131 | -0.148 | -0.1761 | No |
| 140 | Synpo | 13200 | -0.152 | -0.1763 | No |
| 141 | Als2 | 13216 | -0.153 | -0.1739 | No |
| 142 | Llgl1 | 13403 | -0.161 | -0.1801 | No |
| 143 | Capzb | 13408 | -0.161 | -0.1769 | No |
| 144 | Flnb | 13692 | -0.176 | -0.1878 | No |
| 145 | Ralbp1 | 13811 | -0.182 | -0.1900 | No |
| 146 | Kif3b | 13950 | -0.188 | -0.1932 | No |
| 147 | Cenpj | 14043 | -0.192 | -0.1939 | No |
| 148 | Kif22 | 14178 | -0.199 | -0.1966 | No |
| 149 | Ezr | 14331 | -0.206 | -0.2001 | No |
| 150 | Gsn | 14349 | -0.207 | -0.1965 | No |
| 151 | Cdc27 | 14351 | -0.207 | -0.1922 | No |
| 152 | Shroom2 | 14371 | -0.208 | -0.1888 | No |
| 153 | Tubgcp5 | 14431 | -0.210 | -0.1873 | No |
| 154 | Ckap5 | 14432 | -0.210 | -0.1829 | No |
| 155 | Sass6 | 14708 | -0.224 | -0.1924 | No |
| 156 | Cdc42ep4 | 15120 | -0.247 | -0.2084 | No |
| 157 | Nek2 | 15310 | -0.258 | -0.2127 | No |
| 158 | Ndc80 | 15474 | -0.266 | -0.2155 | No |
| 159 | Cep72 | 15476 | -0.267 | -0.2099 | No |
| 160 | Arhgef3 | 15650 | -0.275 | -0.2130 | No |
| 161 | Sorbs2 | 15725 | -0.279 | -0.2109 | No |
| 162 | Arl8a | 16140 | -0.304 | -0.2259 | No |
| 163 | Dock4 | 16250 | -0.312 | -0.2249 | No |
| 164 | Tubd1 | 16537 | -0.331 | -0.2327 | No |
| 165 | Tuba4a | 16704 | -0.345 | -0.2339 | No |
| 166 | Bub1 | 16799 | -0.351 | -0.2313 | No |
| 167 | Top2a | 17158 | -0.376 | -0.2419 | Yes |
| 168 | Prc1 | 17182 | -0.378 | -0.2351 | Yes |
| 169 | Anln | 17258 | -0.383 | -0.2308 | Yes |
| 170 | Birc5 | 17267 | -0.384 | -0.2231 | Yes |
| 171 | Aurka | 17331 | -0.388 | -0.2181 | Yes |
| 172 | Shroom1 | 17349 | -0.390 | -0.2107 | Yes |
| 173 | Arhgap27 | 17687 | -0.424 | -0.2191 | Yes |
| 174 | Cenpf | 17701 | -0.427 | -0.2107 | Yes |
| 175 | Myo1e | 17709 | -0.427 | -0.2020 | Yes |
| 176 | Arap3 | 17727 | -0.428 | -0.1938 | Yes |
| 177 | Kif11 | 17828 | -0.441 | -0.1896 | Yes |
| 178 | Smc4 | 17869 | -0.445 | -0.1822 | Yes |
| 179 | Cdk1 | 17907 | -0.449 | -0.1746 | Yes |
| 180 | Kif15 | 17978 | -0.455 | -0.1686 | Yes |
| 181 | Espl1 | 18062 | -0.465 | -0.1630 | Yes |
| 182 | Racgap1 | 18199 | -0.484 | -0.1598 | Yes |
| 183 | Kif4 | 18342 | -0.503 | -0.1564 | Yes |
| 184 | Uxt | 18481 | -0.523 | -0.1525 | Yes |
| 185 | Cenpe | 18524 | -0.533 | -0.1433 | Yes |
| 186 | Kif23 | 18546 | -0.537 | -0.1330 | Yes |
| 187 | Dlgap5 | 18699 | -0.563 | -0.1289 | Yes |
| 188 | Marcks | 18751 | -0.574 | -0.1194 | Yes |
| 189 | Kif20b | 18972 | -0.632 | -0.1173 | Yes |
| 190 | Ect2 | 19077 | -0.667 | -0.1086 | Yes |
| 191 | Pif1 | 19094 | -0.673 | -0.0951 | Yes |
| 192 | Tpx2 | 19231 | -0.736 | -0.0865 | Yes |
| 193 | Kif2c | 19242 | -0.742 | -0.0713 | Yes |
| 194 | Ccnb2 | 19348 | -0.820 | -0.0593 | Yes |
| 195 | Cdc42ep2 | 19374 | -0.839 | -0.0428 | Yes |
| 196 | Nusap1 | 19473 | -1.020 | -0.0262 | Yes |
| 197 | Plk1 | 19506 | -1.325 | 0.0003 | Yes |

