Details for gene set HALLMARK_G2M

Table: GSEA Results Summary

Dataset	MPP.MPP_Pheno.cls#Group1_versus_Group3.MPP_Pheno.cls#Group1_versus_Group3_repos
Phenotype	MPP_Pheno.cls#Group1_versus_Group3_repos
Upregulated in class	2
GeneSet	HALLMARK_G2M_CHECKPOINT
Enrichment Score (ES)	-0.34788308
Normalized Enrichment Score (NES)	-1.2448826
Nominal p-value	0.2755102
FDR q-value	1.0
FWER p-Value	0.936

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Tfdp1	66	0.804	0.0109	No
2	Hnrnpd	454	0.562	0.0008	No
3	E2f1	503	0.549	0.0081	No
4	Rasal2	633	0.517	0.0106	No
5	Numa1	694	0.504	0.0165	No
6	Smc1a	908	0.471	0.0138	No
7	Dr1	940	0.466	0.0205	No
8	Cdkn2c	1019	0.452	0.0245	No
9	Mcm6	1032	0.451	0.0319	No
10	Hnrnpu	1059	0.446	0.0385	No
11	Slc12a2	1137	0.435	0.0422	No
12	Slc7a5	1139	0.435	0.0499	No
13	Chek1	1160	0.432	0.0565	No
14	Cdc6	1200	0.428	0.0621	No
15	Kpnb1	1212	0.427	0.0691	No
16	Cdc25a	1243	0.423	0.0751	No
17	Mcm3	1302	0.413	0.0794	No
18	Nolc1	1456	0.396	0.0786	No
19	Mybl2	1587	0.381	0.0786	No
20	Hspa8	1714	0.369	0.0786	No
21	Smarcc1	1863	0.357	0.0773	No
22	Srsf10	2003	0.344	0.0762	No
23	Mcm2	2089	0.336	0.0778	No
24	Gins2	2104	0.334	0.0830	No
25	Tnpo2	2143	0.332	0.0870	No
26	Lig3	2423	0.313	0.0781	No
27	Ccnt1	2480	0.309	0.0807	No
28	Abl1	2653	0.299	0.0771	No
29	Ncl	2685	0.297	0.0808	No
30	Uck2	2767	0.292	0.0817	No
31	Mcm5	2771	0.291	0.0868	No
32	E2f4	2837	0.286	0.0885	No
33	Notch2	3126	0.267	0.0783	No
34	Chaf1a	3196	0.262	0.0794	No
35	Upf1	3198	0.262	0.0840	No
36	Rad54l	3305	0.254	0.0830	No
37	Cul1	3507	0.244	0.0770	No
38	Nasp	3582	0.241	0.0774	No
39	Efna5	3598	0.240	0.0809	No
40	Pola2	3727	0.233	0.0784	No
41	Ilf3	3733	0.233	0.0823	No
42	Slc38a1	3744	0.233	0.0859	No
43	Syncrip	3774	0.231	0.0885	No
44	Cdc7	3874	0.226	0.0874	No
45	E2f3	3971	0.221	0.0864	No
46	Smad3	4199	0.209	0.0784	No
47	Sfpq	4241	0.207	0.0799	No
48	Rbl1	4250	0.207	0.0832	No
49	Fancc	4400	0.199	0.0790	No
50	Rad21	4497	0.196	0.0775	No
51	Hif1a	4788	0.181	0.0657	No
52	Ss18	4803	0.180	0.0682	No
53	H2bc12	4833	0.179	0.0699	No
54	Tacc3	4988	0.172	0.0650	No
55	Rad23b	5050	0.169	0.0648	No
56	Gspt1	5184	0.165	0.0609	No
57	Lbr	5256	0.162	0.0601	No
58	Slc7a1	5315	0.160	0.0599	No
59	Nsd2	5341	0.159	0.0614	No
60	Prpf4b	5357	0.158	0.0635	No
61	Pole	5437	0.154	0.0621	No
62	Xpo1	5818	0.135	0.0448	No
63	Nup50	6021	0.126	0.0366	No
64	Nup98	6085	0.123	0.0356	No
65	Exo1	6091	0.123	0.0375	No
66	Cul4a	6099	0.123	0.0393	No
67	Hira	6132	0.122	0.0398	No
68	Mapk14	6198	0.119	0.0386	No
69	Pafah1b1	6202	0.119	0.0405	No
70	Lmnb1	6274	0.116	0.0389	No
71	Tle3	6290	0.116	0.0402	No
72	Ezh2	6388	0.114	0.0372	No
73	Prim2	6423	0.113	0.0375	No
74	Kif5b	6514	0.110	0.0348	No
75	Mtf2	6698	0.102	0.0271	No
76	Hmga1b	6780	0.098	0.0246	No
77	Egf	6875	0.093	0.0214	No
78	Pml	7006	0.089	0.0163	No
79	Atf5	7046	0.087	0.0158	No
80	G3bp1	7113	0.084	0.0139	No
81	Ythdc1	7122	0.084	0.0150	No
82	Pds5b	7253	0.079	0.0097	No
83	Rps6ka5	7265	0.079	0.0105	No
84	Ctcf	7504	0.068	-0.0006	No
85	Dkc1	7603	0.064	-0.0046	No
86	Srsf1	7756	0.059	-0.0114	No
87	Arid4a	7798	0.057	-0.0125	No
88	Stag1	7879	0.053	-0.0157	No
89	Tra2b	8027	0.048	-0.0224	No
90	Mnat1	8164	0.044	-0.0287	No
91	Ewsr1	8198	0.042	-0.0297	No
92	Cdc45	8342	0.036	-0.0364	No
93	Dtymk	8369	0.035	-0.0372	No
94	Srsf2	8555	0.028	-0.0462	No
95	Odc1	8651	0.025	-0.0507	No
96	Brca2	8848	0.017	-0.0606	No
97	Casp8ap2	8880	0.016	-0.0619	No
98	Atrx	8893	0.016	-0.0622	No
99	Myc	9017	0.011	-0.0684	No
100	Ddx39a	9359	-0.000	-0.0860	No
101	Cul5	9409	-0.002	-0.0885	No
102	Top1	9558	-0.008	-0.0960	No
103	Ttk	9786	-0.016	-0.1075	No
104	Katna1	9839	-0.019	-0.1099	No
105	Wrn	9908	-0.021	-0.1130	No
106	Fbxo5	9966	-0.023	-0.1155	No
107	Bard1	9986	-0.023	-0.1161	No
108	Orc6	10316	-0.037	-0.1325	No
109	Cdkn1b	10345	-0.038	-0.1333	No
110	Cul3	10422	-0.041	-0.1365	No
111	Chmp1a	10485	-0.043	-0.1389	No
112	Traip	10494	-0.043	-0.1386	No
113	Meis1	10573	-0.047	-0.1418	No
114	Foxn3	10586	-0.047	-0.1416	No
115	Ccnd1	10616	-0.048	-0.1422	No
116	Amd1	11166	-0.071	-0.1694	No
117	Suv39h1	11406	-0.078	-0.1804	No
118	Orc5	11467	-0.081	-0.1820	No
119	Tent4a	12301	-0.114	-0.2231	No
120	Incenp	12633	-0.128	-0.2380	No
121	Pbk	12669	-0.130	-0.2375	No
122	Sap30	12786	-0.135	-0.2411	No
123	Prmt5	12984	-0.144	-0.2487	No
124	Tmpo	13163	-0.150	-0.2553	No
125	Snrpd1	13429	-0.162	-0.2661	No
126	Bcl3	13687	-0.176	-0.2763	No
127	Rpa2	13760	-0.179	-0.2768	No
128	Cks1b	13769	-0.180	-0.2740	No
129	H2az1	14077	-0.194	-0.2865	No
130	Smc2	14119	-0.196	-0.2851	No
131	Kif22	14178	-0.199	-0.2846	No
132	Hus1	14323	-0.206	-0.2884	No
133	Cdc27	14351	-0.207	-0.2861	No
134	Map3k20	14517	-0.215	-0.2908	No
135	Polq	14576	-0.218	-0.2899	No
136	E2f2	14606	-0.219	-0.2876	No
137	Cdk4	14780	-0.227	-0.2925	No
138	Cbx1	14953	-0.237	-0.2972	No
139	Ccna2	15046	-0.243	-0.2976	No
140	Nek2	15310	-0.258	-0.3067	No
141	Ndc80	15474	-0.266	-0.3104	No
142	Meis2	15634	-0.274	-0.3137	No
143	Odf2	15697	-0.277	-0.3120	No
144	Sqle	15869	-0.287	-0.3158	No
145	Stil	15937	-0.292	-0.3140	No
146	Pura	16103	-0.302	-0.3172	No
147	Dmd	16314	-0.316	-0.3225	No
148	Hmgb3	16472	-0.327	-0.3248	No
149	Plk4	16631	-0.338	-0.3269	No
150	Bub1	16799	-0.351	-0.3294	No
151	Top2a	17158	-0.376	-0.3412	Yes
152	Prc1	17182	-0.378	-0.3357	Yes
153	Birc5	17267	-0.384	-0.3332	Yes
154	Cdc20	17283	-0.385	-0.3271	Yes
155	Aurka	17331	-0.388	-0.3227	Yes
156	Kmt5a	17340	-0.389	-0.3162	Yes
157	H2az2	17550	-0.410	-0.3197	Yes
158	Ccnf	17569	-0.412	-0.3133	Yes
159	Pttg1	17647	-0.419	-0.3099	Yes
160	Cenpf	17701	-0.427	-0.3050	Yes
161	Tgfb1	17706	-0.427	-0.2976	Yes
162	Cks2	17738	-0.430	-0.2916	Yes
163	Kif11	17828	-0.441	-0.2884	Yes
164	Smc4	17869	-0.445	-0.2825	Yes
165	Cdk1	17907	-0.449	-0.2765	Yes
166	Troap	17963	-0.453	-0.2713	Yes
167	Kif15	17978	-0.455	-0.2639	Yes
168	Espl1	18062	-0.465	-0.2599	Yes
169	Hmmr	18168	-0.481	-0.2568	Yes
170	Racgap1	18199	-0.484	-0.2498	Yes
171	Stmn1	18280	-0.495	-0.2451	Yes
172	Kif4	18342	-0.503	-0.2393	Yes
173	H2ax	18412	-0.512	-0.2338	Yes
174	Cenpe	18524	-0.533	-0.2301	Yes
175	Kif23	18546	-0.537	-0.2216	Yes
176	Ube2s	18655	-0.554	-0.2174	Yes
177	Mad2l1	18681	-0.560	-0.2087	Yes
178	Jpt1	18687	-0.561	-0.1990	Yes
179	Marcks	18751	-0.574	-0.1921	Yes
180	Mki67	18937	-0.619	-0.1907	Yes
181	Kif20b	18972	-0.632	-0.1812	Yes
182	Dbf4	18992	-0.638	-0.1708	Yes
183	Knl1	19093	-0.673	-0.1640	Yes
184	Aurkb	19139	-0.687	-0.1542	Yes
185	Bub3	19198	-0.717	-0.1444	Yes
186	Tpx2	19231	-0.736	-0.1330	Yes
187	Kif2c	19242	-0.742	-0.1203	Yes
188	Ccnb2	19348	-0.820	-0.1112	Yes
189	Ube2c	19395	-0.866	-0.0981	Yes
190	Cdc25b	19415	-0.899	-0.0832	Yes
191	Nusap1	19473	-1.020	-0.0680	Yes
192	Cenpa	19498	-1.222	-0.0475	Yes
193	Plk1	19506	-1.325	-0.0243	Yes
194	Cdkn3	19509	-1.383	0.0002	Yes