| Dataset | MPP.MPP_Pheno.cls#Group1_versus_Group3.MPP_Pheno.cls#Group1_versus_Group3_repos |
| Phenotype | MPP_Pheno.cls#Group1_versus_Group3_repos |
| Upregulated in class | 2 |
| GeneSet | HALLMARK_ALLOGRAFT_REJECTION |
| Enrichment Score (ES) | -0.26999664 |
| Normalized Enrichment Score (NES) | -1.0051349 |
| Nominal p-value | 0.46067417 |
| FDR q-value | 0.8874747 |
| FWER p-Value | 0.998 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Lif | 83 | 0.771 | 0.0179 | No |
| 2 | Wars1 | 617 | 0.522 | 0.0054 | No |
| 3 | Il11 | 843 | 0.482 | 0.0077 | No |
| 4 | Stab1 | 921 | 0.469 | 0.0172 | No |
| 5 | Hcls1 | 961 | 0.463 | 0.0285 | No |
| 6 | Fgr | 1003 | 0.455 | 0.0395 | No |
| 7 | Eif3a | 1132 | 0.436 | 0.0454 | No |
| 8 | Acvr2a | 1495 | 0.392 | 0.0380 | No |
| 9 | Cd28 | 1609 | 0.379 | 0.0431 | No |
| 10 | Irf8 | 1876 | 0.356 | 0.0396 | No |
| 11 | Traf2 | 1918 | 0.352 | 0.0476 | No |
| 12 | Tlr2 | 2035 | 0.341 | 0.0514 | No |
| 13 | Lck | 2180 | 0.328 | 0.0535 | No |
| 14 | Bcat1 | 2357 | 0.316 | 0.0535 | No |
| 15 | Jak2 | 2439 | 0.312 | 0.0583 | No |
| 16 | Akt1 | 2445 | 0.311 | 0.0670 | No |
| 17 | Itgal | 2459 | 0.310 | 0.0752 | No |
| 18 | Tap2 | 2637 | 0.300 | 0.0747 | No |
| 19 | Cd247 | 2816 | 0.287 | 0.0738 | No |
| 20 | Tpd52 | 2842 | 0.285 | 0.0807 | No |
| 21 | Il16 | 3315 | 0.253 | 0.0636 | No |
| 22 | Lcp2 | 3375 | 0.251 | 0.0678 | No |
| 23 | Il12rb1 | 3441 | 0.248 | 0.0716 | No |
| 24 | Glmn | 3649 | 0.236 | 0.0677 | No |
| 25 | Mrpl3 | 3720 | 0.234 | 0.0708 | No |
| 26 | Nlrp3 | 3884 | 0.226 | 0.0689 | No |
| 27 | Igsf6 | 4433 | 0.198 | 0.0463 | No |
| 28 | C2 | 4564 | 0.192 | 0.0451 | No |
| 29 | Ccr5 | 4624 | 0.189 | 0.0475 | No |
| 30 | Eif4g3 | 4741 | 0.183 | 0.0468 | No |
| 31 | Tlr6 | 4749 | 0.183 | 0.0517 | No |
| 32 | Hif1a | 4788 | 0.181 | 0.0550 | No |
| 33 | Cd80 | 5095 | 0.167 | 0.0440 | No |
| 34 | Flna | 5205 | 0.164 | 0.0431 | No |
| 35 | Galnt1 | 5323 | 0.159 | 0.0416 | No |
| 36 | Tlr1 | 5704 | 0.141 | 0.0260 | No |
| 37 | Ikbkb | 6229 | 0.118 | 0.0024 | No |
| 38 | Ube2n | 6311 | 0.115 | 0.0015 | No |
| 39 | Tap1 | 6559 | 0.108 | -0.0081 | No |
| 40 | Ccr2 | 6617 | 0.105 | -0.0080 | No |
| 41 | Nck1 | 6946 | 0.091 | -0.0223 | No |
| 42 | Brca1 | 7119 | 0.084 | -0.0288 | No |
| 43 | Trat1 | 7146 | 0.083 | -0.0277 | No |
| 44 | Socs5 | 7415 | 0.072 | -0.0395 | No |
| 45 | Abce1 | 7503 | 0.068 | -0.0420 | No |
| 46 | Il4ra | 7550 | 0.067 | -0.0425 | No |
| 47 | Map3k7 | 7592 | 0.065 | -0.0427 | No |
| 48 | St8sia4 | 7604 | 0.064 | -0.0415 | No |
| 49 | Ccnd3 | 7737 | 0.059 | -0.0466 | No |
| 50 | Stat4 | 7941 | 0.051 | -0.0556 | No |
| 51 | Map4k1 | 8033 | 0.048 | -0.0589 | No |
| 52 | Abi1 | 8046 | 0.048 | -0.0582 | No |
| 53 | Eif3j1 | 8155 | 0.044 | -0.0625 | No |
| 54 | Ptpn6 | 8209 | 0.042 | -0.0640 | No |
| 55 | F2r | 8437 | 0.033 | -0.0748 | No |
| 56 | Ccnd2 | 8574 | 0.027 | -0.0810 | No |
| 57 | Cdkn2a | 9130 | 0.007 | -0.1095 | No |
| 58 | H2-Aa | 9155 | 0.007 | -0.1105 | No |
| 59 | Itk | 9776 | -0.016 | -0.1421 | No |
| 60 | Ets1 | 9971 | -0.023 | -0.1514 | No |
| 61 | Tgfb2 | 10008 | -0.024 | -0.1526 | No |
| 62 | Stat1 | 10240 | -0.034 | -0.1635 | No |
| 63 | Spi1 | 10258 | -0.035 | -0.1634 | No |
| 64 | Srgn | 10310 | -0.036 | -0.1650 | No |
| 65 | Cd1d2 | 10600 | -0.048 | -0.1786 | No |
| 66 | Ly86 | 10743 | -0.053 | -0.1844 | No |
| 67 | Elf4 | 11062 | -0.067 | -0.1989 | No |
| 68 | Ube2d1 | 11190 | -0.071 | -0.2034 | No |
| 69 | H2-Ob | 11279 | -0.075 | -0.2057 | No |
| 70 | Cd86 | 11394 | -0.078 | -0.2094 | No |
| 71 | Fas | 11413 | -0.079 | -0.2081 | No |
| 72 | Ptprc | 11494 | -0.082 | -0.2098 | No |
| 73 | Npm1 | 11652 | -0.088 | -0.2154 | No |
| 74 | Irf7 | 11744 | -0.091 | -0.2175 | No |
| 75 | Ccr1 | 11901 | -0.098 | -0.2227 | No |
| 76 | Zap70 | 11924 | -0.099 | -0.2210 | No |
| 77 | Ripk2 | 11944 | -0.099 | -0.2191 | No |
| 78 | Il18 | 11968 | -0.100 | -0.2174 | No |
| 79 | Bcl10 | 12115 | -0.106 | -0.2219 | No |
| 80 | Ctss | 12206 | -0.110 | -0.2234 | No |
| 81 | Prkcb | 12348 | -0.116 | -0.2274 | No |
| 82 | Ncf4 | 12358 | -0.116 | -0.2245 | No |
| 83 | Ccl5 | 12451 | -0.121 | -0.2258 | No |
| 84 | Tlr3 | 12526 | -0.123 | -0.2260 | No |
| 85 | Icam1 | 12588 | -0.125 | -0.2256 | No |
| 86 | Irf4 | 12634 | -0.128 | -0.2242 | No |
| 87 | Gcnt1 | 12768 | -0.134 | -0.2272 | No |
| 88 | Csf1 | 12827 | -0.137 | -0.2263 | No |
| 89 | Lyn | 12877 | -0.139 | -0.2248 | No |
| 90 | Il4 | 13081 | -0.148 | -0.2310 | No |
| 91 | Mtif2 | 13133 | -0.149 | -0.2294 | No |
| 92 | Bcl3 | 13687 | -0.176 | -0.2529 | No |
| 93 | Rpl9 | 13705 | -0.177 | -0.2486 | No |
| 94 | Cd47 | 13734 | -0.178 | -0.2450 | No |
| 95 | Tapbp | 13798 | -0.181 | -0.2430 | No |
| 96 | Eif5a | 14103 | -0.195 | -0.2531 | No |
| 97 | Cxcr3 | 14249 | -0.202 | -0.2547 | No |
| 98 | Il15 | 14317 | -0.206 | -0.2523 | No |
| 99 | Ly75 | 14661 | -0.221 | -0.2636 | Yes |
| 100 | Eif3d | 14757 | -0.226 | -0.2620 | Yes |
| 101 | Rpl3l | 14816 | -0.229 | -0.2584 | Yes |
| 102 | Socs1 | 14993 | -0.240 | -0.2606 | Yes |
| 103 | Was | 15007 | -0.240 | -0.2544 | Yes |
| 104 | Pf4 | 15098 | -0.246 | -0.2519 | Yes |
| 105 | Psmb10 | 15271 | -0.256 | -0.2534 | Yes |
| 106 | H2-Oa | 15274 | -0.256 | -0.2462 | Yes |
| 107 | Ifnar2 | 15481 | -0.267 | -0.2491 | Yes |
| 108 | Il27ra | 15703 | -0.278 | -0.2525 | Yes |
| 109 | Rps3a1 | 15829 | -0.285 | -0.2508 | Yes |
| 110 | Degs1 | 15888 | -0.289 | -0.2455 | Yes |
| 111 | Il7 | 15932 | -0.292 | -0.2393 | Yes |
| 112 | Prkcg | 16060 | -0.299 | -0.2372 | Yes |
| 113 | Cfp | 16326 | -0.317 | -0.2418 | Yes |
| 114 | Il2 | 16389 | -0.322 | -0.2357 | Yes |
| 115 | Cd4 | 16401 | -0.323 | -0.2270 | Yes |
| 116 | Ache | 16405 | -0.324 | -0.2178 | Yes |
| 117 | Cd96 | 16423 | -0.325 | -0.2093 | Yes |
| 118 | Il18rap | 16429 | -0.325 | -0.2002 | Yes |
| 119 | Itgb2 | 16431 | -0.325 | -0.1909 | Yes |
| 120 | Rps9 | 16587 | -0.335 | -0.1893 | Yes |
| 121 | Csk | 16627 | -0.338 | -0.1816 | Yes |
| 122 | Fcgr2b | 16659 | -0.341 | -0.1734 | Yes |
| 123 | Tnf | 16839 | -0.353 | -0.1724 | Yes |
| 124 | Ifngr2 | 16880 | -0.355 | -0.1643 | Yes |
| 125 | Nme1 | 16897 | -0.356 | -0.1548 | Yes |
| 126 | H2-DMa | 16928 | -0.359 | -0.1461 | Yes |
| 127 | Ifngr1 | 17017 | -0.366 | -0.1401 | Yes |
| 128 | Cd74 | 17117 | -0.373 | -0.1345 | Yes |
| 129 | Il2rg | 17155 | -0.376 | -0.1255 | Yes |
| 130 | Il10 | 17213 | -0.379 | -0.1176 | Yes |
| 131 | Cd79a | 17292 | -0.386 | -0.1105 | Yes |
| 132 | H2-DMb2 | 17530 | -0.408 | -0.1110 | Yes |
| 133 | Tgfb1 | 17706 | -0.427 | -0.1077 | Yes |
| 134 | Crtam | 17910 | -0.449 | -0.1053 | Yes |
| 135 | Il12a | 17993 | -0.457 | -0.0964 | Yes |
| 136 | Cd40 | 17996 | -0.458 | -0.0833 | Yes |
| 137 | B2m | 18119 | -0.474 | -0.0759 | Yes |
| 138 | Gpr65 | 18121 | -0.474 | -0.0623 | Yes |
| 139 | Hdac9 | 18147 | -0.478 | -0.0499 | Yes |
| 140 | Ltb | 18237 | -0.488 | -0.0404 | Yes |
| 141 | Thy1 | 18293 | -0.496 | -0.0290 | Yes |
| 142 | Apbb1 | 18677 | -0.559 | -0.0326 | Yes |
| 143 | Capg | 18806 | -0.583 | -0.0225 | Yes |
| 144 | Elane | 18936 | -0.618 | -0.0113 | Yes |
| 145 | Dyrk3 | 19013 | -0.646 | 0.0033 | Yes |
| 146 | Icosl | 19300 | -0.777 | 0.0109 | Yes |

