Details for gene set HALLMARK_PI3K_AKT_MTOR

Table: GSEA Results Summary

Dataset	MPP.MPP_Pheno.cls#Group1_versus_Group2.MPP_Pheno.cls#Group1_versus_Group2_repos
Phenotype	MPP_Pheno.cls#Group1_versus_Group2_repos
Upregulated in class	1
GeneSet	HALLMARK_PI3K_AKT_MTOR_SIGNALING
Enrichment Score (ES)	-0.22121978
Normalized Enrichment Score (NES)	-1.1240252
Nominal p-value	0.3045977
FDR q-value	0.7764044
FWER p-Value	0.974

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Prkaa2	311	0.639	0.0145	No
2	Camk4	1014	0.475	0.0011	No
3	Pitx2	1155	0.454	0.0155	No
4	Trib3	1293	0.434	0.0292	No
5	Cdk2	1371	0.424	0.0455	No
6	Map2k3	1666	0.393	0.0492	No
7	Prkcb	1672	0.392	0.0676	No
8	Pla2g12a	2150	0.348	0.0597	No
9	Them4	2185	0.345	0.0744	No
10	E2f1	2423	0.325	0.0778	No
11	Adcy2	2709	0.307	0.0777	No
12	Nod1	3204	0.276	0.0655	No
13	Rptor	3304	0.270	0.0733	No
14	Tiam1	3533	0.255	0.0737	No
15	Pten	3824	0.240	0.0703	No
16	Arhgdia	3846	0.238	0.0806	No
17	Pdk1	3877	0.236	0.0903	No
18	Csnk2b	4103	0.225	0.0894	No
19	Dapp1	4829	0.188	0.0611	No
20	Rit1	4981	0.181	0.0620	No
21	Traf2	5243	0.169	0.0566	No
22	Akt1s1	5607	0.152	0.0452	No
23	Tnfrsf1a	5682	0.148	0.0485	No
24	Pin1	5731	0.146	0.0530	No
25	Prkar2a	5892	0.140	0.0514	No
26	Map2k6	5950	0.137	0.0550	No
27	Acaca	6091	0.130	0.0540	No
28	Gna14	6169	0.127	0.0561	No
29	Lck	6569	0.113	0.0410	No
30	Rps6ka1	6640	0.110	0.0426	No
31	Ptpn11	6813	0.103	0.0387	No
32	Mknk1	7027	0.096	0.0323	No
33	Sfn	7544	0.076	0.0094	No
34	Cab39	8205	0.051	-0.0222	No
35	Pik3r3	8631	0.036	-0.0423	No
36	Gsk3b	8978	0.025	-0.0590	No
37	Tbk1	9253	0.014	-0.0724	No
38	Pak4	9400	0.009	-0.0795	No
39	Mapk8	9750	-0.003	-0.0973	No
40	Grk2	10083	-0.014	-0.1137	No
41	Plcg1	10194	-0.017	-0.1186	No
42	Pfn1	10236	-0.019	-0.1198	No
43	Grb2	10247	-0.019	-0.1194	No
44	Vav3	10475	-0.027	-0.1298	No
45	Map3k7	10652	-0.033	-0.1373	No
46	Mapk9	10825	-0.039	-0.1442	No
47	Cltc	11068	-0.048	-0.1544	No
48	Eif4e	11151	-0.050	-0.1562	No
49	Prkag1	11252	-0.054	-0.1588	No
50	Mknk2	11260	-0.054	-0.1566	No
51	Mapk1	11588	-0.065	-0.1703	No
52	Nck1	11779	-0.073	-0.1766	No
53	Hras	11787	-0.073	-0.1735	No
54	Plcb1	11809	-0.074	-0.1710	No
55	Tsc2	11987	-0.081	-0.1763	No
56	Actr2	12118	-0.085	-0.1789	No
57	Pikfyve	12144	-0.086	-0.1761	No
58	Cdk1	12194	-0.089	-0.1744	No
59	Cxcr4	12275	-0.092	-0.1741	No
60	Ap2m1	12393	-0.097	-0.1755	No
61	Ube2n	12434	-0.099	-0.1728	No
62	Ywhab	12534	-0.102	-0.1730	No
63	Sla	12599	-0.105	-0.1713	No
64	Itpr2	12849	-0.115	-0.1787	No
65	Ripk1	12877	-0.116	-0.1745	No
66	Irak4	13069	-0.124	-0.1784	No
67	Akt1	13255	-0.131	-0.1817	No
68	Mapkap1	13306	-0.133	-0.1779	No
69	Smad2	13321	-0.134	-0.1722	No
70	Hsp90b1	13527	-0.144	-0.1759	No
71	Arf1	13617	-0.148	-0.1734	No
72	Raf1	13757	-0.153	-0.1733	No
73	Stat2	13779	-0.154	-0.1670	No
74	Slc2a1	13871	-0.157	-0.1642	No
75	Actr3	14351	-0.181	-0.1802	No
76	Arpc3	14366	-0.182	-0.1722	No
77	Cab39l	14560	-0.190	-0.1731	No
78	Ube2d3	14893	-0.206	-0.1804	No
79	Ddit3	14965	-0.210	-0.1740	No
80	Cdkn1b	15361	-0.230	-0.1833	No
81	Cdk4	15560	-0.242	-0.1820	No
82	Calr	15640	-0.247	-0.1742	No
83	Atf1	16090	-0.278	-0.1841	No
84	Dusp3	16331	-0.290	-0.1826	No
85	Ppp2r1b	16740	-0.317	-0.1885	No
86	Rac1	16972	-0.334	-0.1844	No
87	Ppp1ca	17687	-0.394	-0.2024	Yes
88	Mapk10	17934	-0.420	-0.1950	Yes
89	Sqstm1	18336	-0.471	-0.1932	Yes
90	Myd88	18545	-0.501	-0.1799	Yes
91	Ecsit	18549	-0.501	-0.1561	Yes
92	Nfkbib	18568	-0.504	-0.1330	Yes
93	Cdkn1a	18710	-0.528	-0.1150	Yes
94	Cfl1	18836	-0.551	-0.0952	Yes
95	Il4	18877	-0.562	-0.0704	Yes
96	Il2rg	18890	-0.565	-0.0440	Yes
97	Rps6ka3	19382	-0.785	-0.0318	Yes
98	Ralb	19392	-0.804	0.0062	Yes