| Dataset | MPP.MPP_Pheno.cls#Group1_versus_Group2.MPP_Pheno.cls#Group1_versus_Group2_repos |
| Phenotype | MPP_Pheno.cls#Group1_versus_Group2_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_OXIDATIVE_PHOSPHORYLATION |
| Enrichment Score (ES) | -0.3497037 |
| Normalized Enrichment Score (NES) | -1.2537816 |
| Nominal p-value | 0.25189394 |
| FDR q-value | 0.59760433 |
| FWER p-Value | 0.852 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Mrps22 | 612 | 0.544 | -0.0167 | No |
| 2 | Atp6v0c | 733 | 0.520 | -0.0087 | No |
| 3 | Gpx4 | 836 | 0.501 | -0.0002 | No |
| 4 | Mrps15 | 956 | 0.482 | 0.0069 | No |
| 5 | Hadhb | 976 | 0.480 | 0.0191 | No |
| 6 | Slc25a12 | 1146 | 0.455 | 0.0228 | No |
| 7 | Ldhb | 1515 | 0.409 | 0.0150 | No |
| 8 | Ndufa7 | 1899 | 0.369 | 0.0053 | No |
| 9 | Mpc1 | 1923 | 0.367 | 0.0142 | No |
| 10 | Ndufc1 | 2508 | 0.319 | -0.0073 | No |
| 11 | Bdh2 | 2787 | 0.303 | -0.0133 | No |
| 12 | Cyb5r3 | 2943 | 0.292 | -0.0133 | No |
| 13 | Mrpl15 | 3155 | 0.279 | -0.0166 | No |
| 14 | Uqcr11 | 3405 | 0.264 | -0.0222 | No |
| 15 | Fh1 | 3417 | 0.263 | -0.0156 | No |
| 16 | Atp6v0e | 3587 | 0.252 | -0.0174 | No |
| 17 | Mtx2 | 3735 | 0.245 | -0.0183 | No |
| 18 | Lrpprc | 4044 | 0.228 | -0.0280 | No |
| 19 | Pdp1 | 4695 | 0.194 | -0.0563 | No |
| 20 | Uqcrb | 5226 | 0.170 | -0.0790 | No |
| 21 | Cox7a2 | 5497 | 0.157 | -0.0887 | No |
| 22 | Pdk4 | 5582 | 0.153 | -0.0888 | No |
| 23 | Mtrr | 5681 | 0.148 | -0.0898 | No |
| 24 | Por | 5804 | 0.143 | -0.0922 | No |
| 25 | Nnt | 5913 | 0.139 | -0.0940 | No |
| 26 | Ndufs1 | 5955 | 0.137 | -0.0924 | No |
| 27 | Timm9 | 6079 | 0.131 | -0.0951 | No |
| 28 | Ndufb6 | 6101 | 0.130 | -0.0927 | No |
| 29 | Dlst | 6388 | 0.118 | -0.1042 | No |
| 30 | Mgst3 | 6554 | 0.114 | -0.1096 | No |
| 31 | Mtrf1 | 6769 | 0.104 | -0.1178 | No |
| 32 | Fxn | 6861 | 0.101 | -0.1198 | No |
| 33 | Vdac2 | 6957 | 0.098 | -0.1220 | No |
| 34 | Ndufa4 | 7538 | 0.077 | -0.1499 | No |
| 35 | Cyb5a | 7587 | 0.075 | -0.1503 | No |
| 36 | Ndufa6 | 7590 | 0.074 | -0.1484 | No |
| 37 | Cox10 | 7621 | 0.073 | -0.1479 | No |
| 38 | Timm10 | 7753 | 0.069 | -0.1528 | No |
| 39 | Uqcrq | 7921 | 0.063 | -0.1597 | No |
| 40 | Pmpca | 8049 | 0.058 | -0.1647 | No |
| 41 | Idh3g | 8188 | 0.052 | -0.1704 | No |
| 42 | Mrps30 | 8202 | 0.051 | -0.1697 | No |
| 43 | Acadm | 8375 | 0.045 | -0.1774 | No |
| 44 | Pdhx | 8507 | 0.041 | -0.1830 | No |
| 45 | Pdhb | 8544 | 0.039 | -0.1838 | No |
| 46 | Acat1 | 8611 | 0.037 | -0.1862 | No |
| 47 | Cox11 | 8808 | 0.031 | -0.1955 | No |
| 48 | Uqcrc2 | 9040 | 0.023 | -0.2068 | No |
| 49 | Acaa1a | 9068 | 0.022 | -0.2076 | No |
| 50 | Cox15 | 9257 | 0.014 | -0.2169 | No |
| 51 | Aco2 | 9344 | 0.011 | -0.2211 | No |
| 52 | Ndufs3 | 9450 | 0.007 | -0.2263 | No |
| 53 | Bax | 9493 | 0.006 | -0.2283 | No |
| 54 | Echs1 | 9520 | 0.005 | -0.2295 | No |
| 55 | Dlat | 9541 | 0.004 | -0.2305 | No |
| 56 | Mrpl11 | 9731 | -0.002 | -0.2402 | No |
| 57 | Mfn2 | 9753 | -0.003 | -0.2412 | No |
| 58 | Cyc1 | 9818 | -0.005 | -0.2444 | No |
| 59 | Rhot1 | 9869 | -0.007 | -0.2468 | No |
| 60 | Ndufab1 | 10011 | -0.012 | -0.2537 | No |
| 61 | Atp6ap1 | 10030 | -0.012 | -0.2543 | No |
| 62 | Ndufv2 | 10216 | -0.018 | -0.2634 | No |
| 63 | Sdhc | 10270 | -0.020 | -0.2656 | No |
| 64 | Afg3l2 | 10329 | -0.022 | -0.2680 | No |
| 65 | Casp7 | 10333 | -0.022 | -0.2675 | No |
| 66 | Cox6b1 | 10367 | -0.024 | -0.2686 | No |
| 67 | Vdac3 | 10567 | -0.030 | -0.2781 | No |
| 68 | Cox5b | 10630 | -0.033 | -0.2804 | No |
| 69 | Timm8b | 10680 | -0.034 | -0.2820 | No |
| 70 | Mrpl35 | 10915 | -0.042 | -0.2929 | No |
| 71 | Ndufa9 | 10939 | -0.043 | -0.2929 | No |
| 72 | Cs | 11072 | -0.048 | -0.2984 | No |
| 73 | Atp6v1d | 11077 | -0.048 | -0.2973 | No |
| 74 | Gpi1 | 11336 | -0.057 | -0.3091 | No |
| 75 | Immt | 11535 | -0.064 | -0.3176 | No |
| 76 | Slc25a3 | 11583 | -0.065 | -0.3182 | No |
| 77 | Ndufb3 | 11645 | -0.068 | -0.3195 | No |
| 78 | Rhot2 | 11701 | -0.070 | -0.3205 | No |
| 79 | Mrpl34 | 11784 | -0.073 | -0.3227 | No |
| 80 | Prdx3 | 11820 | -0.074 | -0.3225 | No |
| 81 | Sdha | 11862 | -0.076 | -0.3225 | No |
| 82 | Supv3l1 | 11918 | -0.078 | -0.3232 | No |
| 83 | Abcb7 | 11961 | -0.079 | -0.3232 | No |
| 84 | Cox7c | 12068 | -0.083 | -0.3264 | No |
| 85 | Ech1 | 12090 | -0.084 | -0.3252 | No |
| 86 | Vdac1 | 12324 | -0.094 | -0.3347 | No |
| 87 | Timm13 | 12379 | -0.097 | -0.3348 | No |
| 88 | Acaa2 | 12404 | -0.097 | -0.3334 | No |
| 89 | Tomm70a | 12488 | -0.101 | -0.3349 | No |
| 90 | Cox17 | 12596 | -0.104 | -0.3376 | No |
| 91 | Mdh2 | 12621 | -0.105 | -0.3359 | No |
| 92 | Timm50 | 12729 | -0.110 | -0.3384 | No |
| 93 | Ndufa5 | 12818 | -0.113 | -0.3399 | No |
| 94 | Hccs | 12903 | -0.117 | -0.3410 | No |
| 95 | Hspa9 | 13072 | -0.124 | -0.3463 | Yes |
| 96 | Cox4i1 | 13079 | -0.124 | -0.3432 | Yes |
| 97 | Ndufb2 | 13141 | -0.127 | -0.3429 | Yes |
| 98 | Atp6v1h | 13158 | -0.128 | -0.3402 | Yes |
| 99 | Idh3a | 13236 | -0.130 | -0.3406 | Yes |
| 100 | Atp1b1 | 13253 | -0.131 | -0.3378 | Yes |
| 101 | Acadsb | 13374 | -0.138 | -0.3402 | Yes |
| 102 | Htra2 | 13399 | -0.139 | -0.3377 | Yes |
| 103 | Idh2 | 13419 | -0.139 | -0.3348 | Yes |
| 104 | Ndufa8 | 13422 | -0.140 | -0.3311 | Yes |
| 105 | Ndufs8 | 13424 | -0.140 | -0.3273 | Yes |
| 106 | Iscu | 13428 | -0.140 | -0.3236 | Yes |
| 107 | Got2 | 13432 | -0.140 | -0.3199 | Yes |
| 108 | Ndufs7 | 13491 | -0.142 | -0.3190 | Yes |
| 109 | Pdha1 | 13572 | -0.146 | -0.3192 | Yes |
| 110 | Sdhd | 13642 | -0.149 | -0.3187 | Yes |
| 111 | Atp6v1c1 | 13649 | -0.149 | -0.3149 | Yes |
| 112 | Bckdha | 13700 | -0.150 | -0.3133 | Yes |
| 113 | Ogdh | 13782 | -0.154 | -0.3133 | Yes |
| 114 | Sdhb | 13817 | -0.155 | -0.3108 | Yes |
| 115 | Fdx1 | 13845 | -0.156 | -0.3079 | Yes |
| 116 | Opa1 | 13956 | -0.162 | -0.3092 | Yes |
| 117 | Tcirg1 | 13972 | -0.163 | -0.3055 | Yes |
| 118 | Grpel1 | 13989 | -0.164 | -0.3018 | Yes |
| 119 | Etfa | 14021 | -0.165 | -0.2989 | Yes |
| 120 | Uqcrh | 14028 | -0.166 | -0.2946 | Yes |
| 121 | Phyh | 14032 | -0.166 | -0.2902 | Yes |
| 122 | Ndufa3 | 14139 | -0.171 | -0.2910 | Yes |
| 123 | Ndufb7 | 14170 | -0.173 | -0.2878 | Yes |
| 124 | Phb2 | 14243 | -0.176 | -0.2867 | Yes |
| 125 | Idh3b | 14381 | -0.183 | -0.2888 | Yes |
| 126 | Cox6a1 | 14459 | -0.186 | -0.2876 | Yes |
| 127 | Ndufb5 | 14464 | -0.186 | -0.2827 | Yes |
| 128 | Tomm22 | 14581 | -0.191 | -0.2835 | Yes |
| 129 | Decr1 | 14740 | -0.199 | -0.2862 | Yes |
| 130 | Timm17a | 14865 | -0.204 | -0.2870 | Yes |
| 131 | Cpt1a | 14955 | -0.209 | -0.2859 | Yes |
| 132 | Nqo2 | 15151 | -0.219 | -0.2900 | Yes |
| 133 | Idh1 | 15246 | -0.223 | -0.2887 | Yes |
| 134 | Atp6v0b | 15299 | -0.227 | -0.2852 | Yes |
| 135 | Oxa1l | 15350 | -0.229 | -0.2815 | Yes |
| 136 | Ndufs2 | 15366 | -0.230 | -0.2759 | Yes |
| 137 | Ndufs4 | 15400 | -0.232 | -0.2713 | Yes |
| 138 | Suclg1 | 15426 | -0.233 | -0.2662 | Yes |
| 139 | Etfb | 15567 | -0.242 | -0.2668 | Yes |
| 140 | Ldha | 15631 | -0.247 | -0.2632 | Yes |
| 141 | Glud1 | 15690 | -0.251 | -0.2594 | Yes |
| 142 | Aldh6a1 | 15807 | -0.258 | -0.2583 | Yes |
| 143 | Surf1 | 15821 | -0.259 | -0.2518 | Yes |
| 144 | Cox7a2l | 15838 | -0.260 | -0.2455 | Yes |
| 145 | Hsd17b10 | 15875 | -0.263 | -0.2402 | Yes |
| 146 | Etfdh | 16168 | -0.282 | -0.2476 | Yes |
| 147 | Ndufv1 | 16298 | -0.288 | -0.2463 | Yes |
| 148 | Slc25a5 | 16309 | -0.289 | -0.2389 | Yes |
| 149 | Atp6v1g1 | 16381 | -0.294 | -0.2345 | Yes |
| 150 | Ndufs6 | 16564 | -0.306 | -0.2355 | Yes |
| 151 | Alas1 | 16637 | -0.311 | -0.2307 | Yes |
| 152 | Cox8a | 16780 | -0.320 | -0.2293 | Yes |
| 153 | Acadvl | 16826 | -0.323 | -0.2228 | Yes |
| 154 | Slc25a20 | 16834 | -0.324 | -0.2143 | Yes |
| 155 | Ndufa2 | 16876 | -0.327 | -0.2074 | Yes |
| 156 | Retsat | 17058 | -0.340 | -0.2074 | Yes |
| 157 | Eci1 | 17281 | -0.359 | -0.2091 | Yes |
| 158 | Dld | 17348 | -0.364 | -0.2025 | Yes |
| 159 | Uqcrfs1 | 17399 | -0.369 | -0.1949 | Yes |
| 160 | Cox5a | 17405 | -0.369 | -0.1850 | Yes |
| 161 | Polr2f | 17448 | -0.373 | -0.1770 | Yes |
| 162 | Atp5pb | 17454 | -0.374 | -0.1670 | Yes |
| 163 | Aifm1 | 17469 | -0.375 | -0.1574 | Yes |
| 164 | Maob | 17503 | -0.379 | -0.1487 | Yes |
| 165 | Hadha | 17509 | -0.379 | -0.1386 | Yes |
| 166 | Oat | 17574 | -0.385 | -0.1313 | Yes |
| 167 | Uqcrc1 | 18167 | -0.447 | -0.1496 | Yes |
| 168 | Atp6v1f | 18178 | -0.449 | -0.1378 | Yes |
| 169 | Ndufb8 | 18274 | -0.462 | -0.1301 | Yes |
| 170 | Slc25a11 | 18280 | -0.464 | -0.1176 | Yes |
| 171 | Sucla2 | 18579 | -0.505 | -0.1192 | Yes |
| 172 | Mrps12 | 18623 | -0.513 | -0.1073 | Yes |
| 173 | Atp6v1e1 | 18742 | -0.532 | -0.0988 | Yes |
| 174 | Uqcr10 | 18802 | -0.543 | -0.0869 | Yes |
| 175 | Slc25a4 | 18962 | -0.586 | -0.0791 | Yes |
| 176 | Mrps11 | 19033 | -0.608 | -0.0660 | Yes |
| 177 | Cox6c | 19048 | -0.612 | -0.0499 | Yes |
| 178 | Ndufa1 | 19175 | -0.660 | -0.0383 | Yes |
| 179 | Mdh1 | 19203 | -0.670 | -0.0213 | Yes |
| 180 | Ndufc2 | 19216 | -0.678 | -0.0033 | Yes |
| 181 | Cox7b | 19217 | -0.678 | 0.0153 | Yes |

