Details for gene set HALLMARK_IL6_JAK_STAT3

Table: GSEA Results Summary

Dataset	MPP.MPP_Pheno.cls#Group1_versus_Group2.MPP_Pheno.cls#Group1_versus_Group2_repos
Phenotype	MPP_Pheno.cls#Group1_versus_Group2_repos
Upregulated in class	1
GeneSet	HALLMARK_IL6_JAK_STAT3_SIGNALING
Enrichment Score (ES)	-0.44078967
Normalized Enrichment Score (NES)	-1.4901472
Nominal p-value	0.08719852
FDR q-value	0.45728487
FWER p-Value	0.46

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Il12rb1	740	0.519	-0.0095	No
2	Ebi3	1069	0.465	-0.0008	No
3	Hmox1	1253	0.439	0.0139	No
4	Cxcl10	1826	0.376	0.0052	No
5	Csf2ra	1867	0.372	0.0236	No
6	Tnfrsf21	2024	0.359	0.0353	No
7	Ptpn2	2974	0.290	0.0024	No
8	Cd44	3088	0.283	0.0122	No
9	Tyk2	4179	0.221	-0.0317	No
10	Il15ra	4194	0.220	-0.0203	No
11	Bak1	4467	0.207	-0.0229	No
12	Ccr1	4895	0.185	-0.0347	No
13	Tnfrsf1a	5682	0.148	-0.0670	No
14	Itgb3	6141	0.128	-0.0835	No
15	Socs1	6429	0.117	-0.0918	No
16	Crlf2	6788	0.104	-0.1045	No
17	Ptpn11	6813	0.103	-0.1001	No
18	Jun	6818	0.103	-0.0947	No
19	Il10rb	7423	0.082	-0.1212	No
20	Tnfrsf1b	8081	0.057	-0.1519	No
21	Ifnar1	8195	0.052	-0.1549	No
22	Cbl	9015	0.024	-0.1957	No
23	Stam2	9192	0.017	-0.2038	No
24	Itga4	9303	0.013	-0.2088	No
25	Il13ra1	9504	0.005	-0.2188	No
26	Grb2	10247	-0.019	-0.2559	No
27	Fas	10267	-0.020	-0.2558	No
28	Tlr2	10431	-0.026	-0.2628	No
29	Ifngr1	10642	-0.033	-0.2717	No
30	Irf9	10927	-0.043	-0.2840	No
31	Pim1	11192	-0.051	-0.2947	No
32	Tnf	11414	-0.059	-0.3028	No
33	Ptpn1	11823	-0.074	-0.3198	No
34	Csf3r	11906	-0.077	-0.3197	No
35	Tgfb1	12041	-0.082	-0.3221	No
36	Csf1	12478	-0.100	-0.3390	No
37	Cd9	12553	-0.103	-0.3371	No
38	Stat3	12753	-0.111	-0.3413	No
39	Il9r	13406	-0.139	-0.3672	No
40	Stat1	13413	-0.139	-0.3598	No
41	Stat2	13779	-0.154	-0.3701	No
42	Cd36	13837	-0.156	-0.3645	No
43	Pdgfc	14279	-0.178	-0.3774	No
44	Il17ra	15513	-0.238	-0.4277	Yes
45	Map3k8	15521	-0.239	-0.4149	Yes
46	Il7	15557	-0.241	-0.4034	Yes
47	Pf4	16067	-0.276	-0.4144	Yes
48	Ltbr	16332	-0.290	-0.4120	Yes
49	Il1r1	16762	-0.318	-0.4166	Yes
50	Il3ra	16880	-0.328	-0.4046	Yes
51	Osmr	16965	-0.334	-0.3905	Yes
52	Ltb	17021	-0.337	-0.3748	Yes
53	Il6st	17274	-0.359	-0.3681	Yes
54	Pik3r5	17383	-0.369	-0.3533	Yes
55	Hax1	17412	-0.370	-0.3344	Yes
56	Irf1	17466	-0.375	-0.3166	Yes
57	Tnfrsf12a	17514	-0.380	-0.2981	Yes
58	Il1r2	17537	-0.382	-0.2782	Yes
59	Myd88	18545	-0.501	-0.3024	Yes
60	Dntt	18590	-0.506	-0.2768	Yes
61	Ifngr2	18652	-0.518	-0.2515	Yes
62	Il4ra	18720	-0.529	-0.2258	Yes
63	Acvr1b	18767	-0.537	-0.1987	Yes
64	Il2rg	18890	-0.565	-0.1738	Yes
65	Lepr	18922	-0.574	-0.1438	Yes
66	Il17rb	18948	-0.582	-0.1131	Yes
67	Il18r1	19020	-0.603	-0.0836	Yes
68	Acvrl1	19152	-0.649	-0.0546	Yes
69	Cd38	19172	-0.659	-0.0194	Yes
70	Socs3	19201	-0.670	0.0160	Yes