| Dataset | MPP.MPP_Pheno.cls#Group1_versus_Group2.MPP_Pheno.cls#Group1_versus_Group2_repos |
| Phenotype | MPP_Pheno.cls#Group1_versus_Group2_repos |
| Upregulated in class | 0 |
| GeneSet | HALLMARK_HEME_METABOLISM |
| Enrichment Score (ES) | 0.17338008 |
| Normalized Enrichment Score (NES) | 0.9424369 |
| Nominal p-value | 0.664557 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Slc66a2 | 115 | 0.782 | 0.0143 | Yes |
| 2 | Slc4a1 | 117 | 0.780 | 0.0345 | Yes |
| 3 | P4ha2 | 124 | 0.776 | 0.0543 | Yes |
| 4 | Fbxo7 | 197 | 0.702 | 0.0688 | Yes |
| 5 | Ppp2r5b | 231 | 0.685 | 0.0848 | Yes |
| 6 | Tspo2 | 610 | 0.544 | 0.0794 | Yes |
| 7 | Bpgm | 983 | 0.479 | 0.0726 | Yes |
| 8 | Osbp2 | 1134 | 0.456 | 0.0766 | Yes |
| 9 | Rnf123 | 1282 | 0.435 | 0.0803 | Yes |
| 10 | Gde1 | 1339 | 0.428 | 0.0885 | Yes |
| 11 | Atp6v0a1 | 1451 | 0.416 | 0.0936 | Yes |
| 12 | Bach1 | 1540 | 0.407 | 0.0996 | Yes |
| 13 | Slc11a2 | 1584 | 0.401 | 0.1077 | Yes |
| 14 | Ucp2 | 1629 | 0.396 | 0.1157 | Yes |
| 15 | Map2k3 | 1666 | 0.393 | 0.1240 | Yes |
| 16 | Abcb6 | 1712 | 0.388 | 0.1318 | Yes |
| 17 | Snca | 1743 | 0.385 | 0.1402 | Yes |
| 18 | Marchf8 | 1862 | 0.372 | 0.1437 | Yes |
| 19 | Bnip3l | 2138 | 0.349 | 0.1386 | Yes |
| 20 | Tfdp2 | 2231 | 0.340 | 0.1426 | Yes |
| 21 | Arhgef12 | 2297 | 0.335 | 0.1480 | Yes |
| 22 | Bcam | 2321 | 0.332 | 0.1554 | Yes |
| 23 | Sidt2 | 2462 | 0.322 | 0.1565 | Yes |
| 24 | Slc6a9 | 2497 | 0.320 | 0.1630 | Yes |
| 25 | Slc30a10 | 2723 | 0.306 | 0.1593 | Yes |
| 26 | Trim10 | 2897 | 0.296 | 0.1580 | Yes |
| 27 | Pigq | 3033 | 0.287 | 0.1585 | Yes |
| 28 | Cir1 | 3123 | 0.281 | 0.1612 | Yes |
| 29 | Hagh | 3174 | 0.278 | 0.1658 | Yes |
| 30 | Klf1 | 3182 | 0.278 | 0.1726 | Yes |
| 31 | Slc10a3 | 3557 | 0.254 | 0.1599 | Yes |
| 32 | Btrc | 3687 | 0.247 | 0.1596 | Yes |
| 33 | Foxj2 | 3800 | 0.241 | 0.1601 | Yes |
| 34 | Trim58 | 3872 | 0.237 | 0.1625 | Yes |
| 35 | Pcx | 4157 | 0.222 | 0.1536 | Yes |
| 36 | Btg2 | 4231 | 0.219 | 0.1555 | Yes |
| 37 | Car2 | 4257 | 0.218 | 0.1598 | Yes |
| 38 | Mxi1 | 4269 | 0.217 | 0.1649 | Yes |
| 39 | Slc22a4 | 4320 | 0.215 | 0.1679 | Yes |
| 40 | Rbm5 | 4322 | 0.214 | 0.1734 | Yes |
| 41 | Dcun1d1 | 4501 | 0.205 | 0.1695 | No |
| 42 | Smox | 4803 | 0.190 | 0.1588 | No |
| 43 | Alas2 | 4858 | 0.187 | 0.1609 | No |
| 44 | Mpp1 | 4935 | 0.183 | 0.1617 | No |
| 45 | Spta1 | 5066 | 0.177 | 0.1596 | No |
| 46 | Optn | 5522 | 0.156 | 0.1401 | No |
| 47 | Pgls | 5614 | 0.152 | 0.1393 | No |
| 48 | Tspan5 | 5658 | 0.149 | 0.1410 | No |
| 49 | Ranbp10 | 5708 | 0.147 | 0.1423 | No |
| 50 | Uros | 5718 | 0.147 | 0.1456 | No |
| 51 | Nek7 | 5755 | 0.145 | 0.1475 | No |
| 52 | Tal1 | 5911 | 0.139 | 0.1431 | No |
| 53 | Nnt | 5913 | 0.139 | 0.1466 | No |
| 54 | Glrx5 | 5928 | 0.138 | 0.1495 | No |
| 55 | Selenbp1 | 6059 | 0.132 | 0.1462 | No |
| 56 | Rhag | 6127 | 0.129 | 0.1460 | No |
| 57 | Gmps | 6180 | 0.127 | 0.1466 | No |
| 58 | Trak2 | 6332 | 0.120 | 0.1419 | No |
| 59 | Mgst3 | 6554 | 0.114 | 0.1334 | No |
| 60 | Dcaf10 | 6762 | 0.105 | 0.1255 | No |
| 61 | Foxo3 | 6814 | 0.103 | 0.1255 | No |
| 62 | Mkrn1 | 6871 | 0.101 | 0.1252 | No |
| 63 | Vezf1 | 6890 | 0.100 | 0.1269 | No |
| 64 | Fbxo9 | 6926 | 0.099 | 0.1276 | No |
| 65 | Blvrb | 7015 | 0.096 | 0.1256 | No |
| 66 | Alad | 7257 | 0.087 | 0.1154 | No |
| 67 | Tns1 | 7278 | 0.086 | 0.1166 | No |
| 68 | Usp15 | 7307 | 0.085 | 0.1173 | No |
| 69 | Lrp10 | 7365 | 0.083 | 0.1165 | No |
| 70 | Kdm7a | 7511 | 0.078 | 0.1111 | No |
| 71 | Mospd1 | 7670 | 0.072 | 0.1047 | No |
| 72 | Mocos | 7867 | 0.064 | 0.0963 | No |
| 73 | Igsf3 | 8021 | 0.059 | 0.0899 | No |
| 74 | Gapvd1 | 8247 | 0.050 | 0.0795 | No |
| 75 | Ezh1 | 8322 | 0.047 | 0.0769 | No |
| 76 | Xk | 8369 | 0.045 | 0.0757 | No |
| 77 | Xpo7 | 8384 | 0.044 | 0.0761 | No |
| 78 | Cat | 8398 | 0.044 | 0.0766 | No |
| 79 | Cpox | 8434 | 0.043 | 0.0759 | No |
| 80 | Gclc | 8517 | 0.040 | 0.0727 | No |
| 81 | Mfhas1 | 8714 | 0.034 | 0.0634 | No |
| 82 | Epor | 8743 | 0.033 | 0.0628 | No |
| 83 | Tmem9b | 8878 | 0.028 | 0.0566 | No |
| 84 | Tnrc6b | 9308 | 0.013 | 0.0348 | No |
| 85 | Rcl1 | 9375 | 0.010 | 0.0316 | No |
| 86 | Gata1 | 9577 | 0.002 | 0.0213 | No |
| 87 | Gypc | 9594 | 0.002 | 0.0205 | No |
| 88 | Eif2ak1 | 9612 | 0.001 | 0.0197 | No |
| 89 | Ell2 | 9615 | 0.001 | 0.0196 | No |
| 90 | Mboat2 | 9617 | 0.001 | 0.0196 | No |
| 91 | Ppox | 9749 | -0.003 | 0.0129 | No |
| 92 | Slc7a11 | 9758 | -0.003 | 0.0126 | No |
| 93 | Add2 | 9830 | -0.006 | 0.0090 | No |
| 94 | Marchf2 | 9895 | -0.008 | 0.0059 | No |
| 95 | Daam1 | 10069 | -0.014 | -0.0027 | No |
| 96 | Ctse | 10091 | -0.015 | -0.0034 | No |
| 97 | Rbm38 | 10098 | -0.015 | -0.0033 | No |
| 98 | Ypel5 | 10223 | -0.018 | -0.0092 | No |
| 99 | Pdzk1ip1 | 10238 | -0.019 | -0.0095 | No |
| 100 | Add1 | 10308 | -0.021 | -0.0125 | No |
| 101 | Nfe2 | 10448 | -0.026 | -0.0190 | No |
| 102 | Tcea1 | 10520 | -0.029 | -0.0219 | No |
| 103 | Abcg2 | 10569 | -0.030 | -0.0236 | No |
| 104 | Clcn3 | 10677 | -0.034 | -0.0283 | No |
| 105 | Epb42 | 10707 | -0.035 | -0.0289 | No |
| 106 | Epb41 | 10782 | -0.038 | -0.0317 | No |
| 107 | Cast | 10849 | -0.040 | -0.0341 | No |
| 108 | Lmo2 | 10950 | -0.044 | -0.0381 | No |
| 109 | Slc6a8 | 11155 | -0.051 | -0.0474 | No |
| 110 | Picalm | 11479 | -0.062 | -0.0625 | No |
| 111 | Bsg | 11564 | -0.064 | -0.0651 | No |
| 112 | Fbxo34 | 11641 | -0.068 | -0.0673 | No |
| 113 | Fech | 11655 | -0.068 | -0.0662 | No |
| 114 | Narf | 11732 | -0.072 | -0.0683 | No |
| 115 | Nudt4 | 11988 | -0.081 | -0.0794 | No |
| 116 | Kat2b | 12053 | -0.083 | -0.0806 | No |
| 117 | Myl4 | 12264 | -0.092 | -0.0891 | No |
| 118 | Tyr | 12305 | -0.093 | -0.0887 | No |
| 119 | Sdcbp | 12605 | -0.105 | -0.1015 | No |
| 120 | Rhd | 12629 | -0.106 | -0.0999 | No |
| 121 | Ccdc28a | 12691 | -0.108 | -0.1003 | No |
| 122 | Nfe2l1 | 12700 | -0.108 | -0.0979 | No |
| 123 | Cdc27 | 12827 | -0.114 | -0.1014 | No |
| 124 | Htatip2 | 13151 | -0.127 | -0.1148 | No |
| 125 | Tfrc | 13196 | -0.129 | -0.1138 | No |
| 126 | Agpat4 | 13225 | -0.130 | -0.1118 | No |
| 127 | Htra2 | 13399 | -0.139 | -0.1172 | No |
| 128 | Endod1 | 13461 | -0.141 | -0.1167 | No |
| 129 | Asns | 13521 | -0.144 | -0.1160 | No |
| 130 | Ank1 | 13556 | -0.145 | -0.1140 | No |
| 131 | Rnf19a | 13635 | -0.149 | -0.1142 | No |
| 132 | Sptb | 13644 | -0.149 | -0.1107 | No |
| 133 | Slc25a38 | 13703 | -0.151 | -0.1098 | No |
| 134 | Car1 | 13775 | -0.153 | -0.1095 | No |
| 135 | Slc30a1 | 13852 | -0.156 | -0.1094 | No |
| 136 | Slc2a1 | 13871 | -0.157 | -0.1063 | No |
| 137 | Rap1gap | 14008 | -0.165 | -0.1090 | No |
| 138 | Tmcc2 | 14199 | -0.174 | -0.1143 | No |
| 139 | Kel | 14240 | -0.176 | -0.1118 | No |
| 140 | Mark3 | 14628 | -0.193 | -0.1268 | No |
| 141 | Synj1 | 14779 | -0.200 | -0.1294 | No |
| 142 | E2f2 | 14803 | -0.201 | -0.1254 | No |
| 143 | Hmbs | 14837 | -0.203 | -0.1218 | No |
| 144 | Psmd9 | 14976 | -0.211 | -0.1235 | No |
| 145 | Ermap | 15068 | -0.215 | -0.1226 | No |
| 146 | Acp5 | 15083 | -0.215 | -0.1178 | No |
| 147 | Lpin2 | 15203 | -0.221 | -0.1182 | No |
| 148 | Dmtn | 15301 | -0.227 | -0.1173 | No |
| 149 | Ncoa4 | 15502 | -0.238 | -0.1215 | No |
| 150 | Dcaf11 | 15688 | -0.251 | -0.1246 | No |
| 151 | Lamp2 | 15695 | -0.251 | -0.1184 | No |
| 152 | Minpp1 | 15701 | -0.252 | -0.1121 | No |
| 153 | Nr3c1 | 15708 | -0.252 | -0.1059 | No |
| 154 | Gclm | 15735 | -0.254 | -0.1006 | No |
| 155 | Aldh6a1 | 15807 | -0.258 | -0.0976 | No |
| 156 | C3 | 15933 | -0.267 | -0.0972 | No |
| 157 | Sec14l1 | 16002 | -0.272 | -0.0936 | No |
| 158 | Top1 | 16018 | -0.273 | -0.0873 | No |
| 159 | Hdgf | 16061 | -0.276 | -0.0823 | No |
| 160 | Cdr2 | 16172 | -0.282 | -0.0807 | No |
| 161 | Hebp1 | 16216 | -0.284 | -0.0756 | No |
| 162 | Riok3 | 16244 | -0.285 | -0.0696 | No |
| 163 | Rad23a | 16461 | -0.299 | -0.0730 | No |
| 164 | Ccnd3 | 16534 | -0.303 | -0.0688 | No |
| 165 | Urod | 16635 | -0.311 | -0.0659 | No |
| 166 | Fn3k | 16947 | -0.332 | -0.0734 | No |
| 167 | Adipor1 | 17056 | -0.340 | -0.0702 | No |
| 168 | Khnyn | 17191 | -0.352 | -0.0680 | No |
| 169 | Icam4 | 17333 | -0.363 | -0.0659 | No |
| 170 | Arl2bp | 17398 | -0.369 | -0.0596 | No |
| 171 | Tent5c | 17492 | -0.377 | -0.0547 | No |
| 172 | Ubac1 | 17540 | -0.382 | -0.0472 | No |
| 173 | Bmp2k | 17686 | -0.394 | -0.0445 | No |
| 174 | Acsl6 | 18177 | -0.449 | -0.0582 | No |
| 175 | Blvra | 18360 | -0.473 | -0.0553 | No |
| 176 | Ctsb | 18379 | -0.476 | -0.0439 | No |
| 177 | Prdx2 | 18510 | -0.497 | -0.0377 | No |
| 178 | Klf3 | 18567 | -0.504 | -0.0276 | No |
| 179 | Aldh1l1 | 19088 | -0.626 | -0.0382 | No |
| 180 | Atg4a | 19211 | -0.675 | -0.0270 | No |
| 181 | Ctns | 19378 | -0.780 | -0.0154 | No |
| 182 | H1f0 | 19428 | -0.860 | 0.0043 | No |

