Details for gene set HALLMARK_PI3K_AKT_MTOR

Table: GSEA Results Summary

Dataset	MEP.MEP.mega_Pheno.cls #Group6_versus_Group8.MEP.mega_Pheno.cls #Group6_versus_Group8_repos
Phenotype	MEP.mega_Pheno.cls#Group6_versus_Group8_repos
Upregulated in class	5
GeneSet	HALLMARK_PI3K_AKT_MTOR_SIGNALING
Enrichment Score (ES)	-0.21113762
Normalized Enrichment Score (NES)	-1.0894659
Nominal p-value	0.30167598
FDR q-value	0.5004098
FWER p-Value	0.993

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Tsc2	735	0.532	-0.0100	No
2	Il4	1032	0.482	0.0001	No
3	Tiam1	1105	0.466	0.0211	No
4	Pdk1	1813	0.383	0.0047	No
5	Ube2n	1978	0.372	0.0159	No
6	Arhgdia	2035	0.364	0.0323	No
7	Prkcb	2192	0.353	0.0430	No
8	Ap2m1	2443	0.330	0.0475	No
9	Gna14	2510	0.325	0.0613	No
10	Rptor	2888	0.294	0.0572	No
11	Cdkn1a	2943	0.290	0.0698	No
12	Rit1	2976	0.288	0.0835	No
13	Pak4	3059	0.282	0.0941	No
14	E2f1	3113	0.278	0.1062	No
15	Camk4	3849	0.240	0.0806	No
16	Ppp2r1b	4103	0.224	0.0794	No
17	Acaca	4699	0.201	0.0591	No
18	Prkar2a	5078	0.181	0.0490	No
19	Trib3	5224	0.175	0.0507	No
20	Rps6ka3	5322	0.170	0.0547	No
21	Ptpn11	6001	0.141	0.0269	No
22	Raf1	6049	0.139	0.0318	No
23	Atf1	6313	0.128	0.0249	No
24	Calr	6494	0.120	0.0219	No
25	Smad2	6556	0.117	0.0249	No
26	Adcy2	6663	0.114	0.0254	No
27	Map2k6	6703	0.112	0.0294	No
28	Actr2	6706	0.112	0.0352	No
29	Lck	6738	0.111	0.0394	No
30	Cxcr4	6803	0.107	0.0418	No
31	Mapkap1	6809	0.107	0.0472	No
32	Plcg1	6947	0.103	0.0456	No
33	Vav3	7052	0.099	0.0454	No
34	Grb2	7072	0.098	0.0496	No
35	Pik3r3	7145	0.096	0.0510	No
36	Map3k7	7187	0.094	0.0538	No
37	Mapk1	7434	0.085	0.0455	No
38	Cltc	8669	0.037	-0.0167	No
39	Mknk2	9107	0.021	-0.0384	No
40	Actr3	9160	0.019	-0.0400	No
41	Grk2	9198	0.018	-0.0410	No
42	Hsp90b1	9435	0.010	-0.0528	No
43	Itpr2	9529	0.006	-0.0573	No
44	Tnfrsf1a	9564	0.005	-0.0588	No
45	Pitx2	9729	0.000	-0.0673	No
46	Cdkn1b	10078	-0.006	-0.0851	No
47	Stat2	10100	-0.007	-0.0859	No
48	Pla2g12a	10110	-0.007	-0.0860	No
49	Cdk2	10123	-0.007	-0.0862	No
50	Prkag1	10399	-0.018	-0.0996	No
51	Arf1	10477	-0.020	-0.1025	No
52	Nod1	10492	-0.021	-0.1021	No
53	Mknk1	10855	-0.033	-0.1192	No
54	Gsk3b	10899	-0.035	-0.1196	No
55	Slc2a1	11030	-0.040	-0.1242	No
56	Hras	11055	-0.041	-0.1233	No
57	Tbk1	11445	-0.054	-0.1407	No
58	Traf2	11559	-0.058	-0.1435	No
59	Pten	11677	-0.062	-0.1463	No
60	Mapk8	11854	-0.069	-0.1518	No
61	Mapk9	12122	-0.079	-0.1615	No
62	Pikfyve	12505	-0.095	-0.1764	No
63	Irak4	12545	-0.096	-0.1733	No
64	Rac1	12728	-0.105	-0.1772	No
65	Cab39	13111	-0.121	-0.1906	No
66	Sfn	13405	-0.133	-0.1988	No
67	Prkaa2	13425	-0.135	-0.1927	No
68	Ube2d3	13583	-0.141	-0.1933	No
69	Dapp1	13926	-0.158	-0.2028	Yes
70	Eif4e	14080	-0.165	-0.2020	Yes
71	Plcb1	14166	-0.168	-0.1974	Yes
72	Csnk2b	14301	-0.175	-0.1951	Yes
73	Ralb	14392	-0.178	-0.1904	Yes
74	Cab39l	14462	-0.181	-0.1843	Yes
75	Myd88	14697	-0.193	-0.1863	Yes
76	Sqstm1	14954	-0.206	-0.1887	Yes
77	Pfn1	14956	-0.206	-0.1778	Yes
78	Ripk1	14970	-0.207	-0.1675	Yes
79	Sla	15187	-0.219	-0.1671	Yes
80	Ywhab	15255	-0.223	-0.1588	Yes
81	Rps6ka1	15392	-0.230	-0.1536	Yes
82	Akt1	15786	-0.247	-0.1610	Yes
83	Them4	15901	-0.254	-0.1534	Yes
84	Akt1s1	16082	-0.266	-0.1487	Yes
85	Map2k3	16191	-0.273	-0.1398	Yes
86	Mapk10	16489	-0.293	-0.1397	Yes
87	Nck1	16631	-0.302	-0.1311	Yes
88	Cdk4	16922	-0.321	-0.1291	Yes
89	Cdk1	16948	-0.323	-0.1133	Yes
90	Fgf17	16983	-0.325	-0.0978	Yes
91	Pin1	17163	-0.338	-0.0892	Yes
92	Dusp3	17310	-0.350	-0.0782	Yes
93	Nfkbib	17393	-0.358	-0.0634	Yes
94	Il2rg	17493	-0.367	-0.0491	Yes
95	Cfl1	17677	-0.384	-0.0382	Yes
96	Arpc3	18455	-0.482	-0.0531	Yes
97	Ecsit	18682	-0.526	-0.0369	Yes
98	Ppp1ca	18907	-0.586	-0.0175	Yes
99	Ddit3	19174	-0.720	0.0069	Yes