Details for gene set HALLMARK_TNFA_SIGNALING_VIA

Table: GSEA Results Summary

Dataset	MEP.MEP.mega_Pheno.cls #Group3_versus_Group4.MEP.mega_Pheno.cls #Group3_versus_Group4_repos
Phenotype	MEP.mega_Pheno.cls#Group3_versus_Group4_repos
Upregulated in class	2
GeneSet	HALLMARK_TNFA_SIGNALING_VIA_NFKB
Enrichment Score (ES)	0.22029428
Normalized Enrichment Score (NES)	0.80773586
Nominal p-value	0.7923729
FDR q-value	1.0
FWER p-Value	1.0

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Ccnd1	6	1.387	0.0336	Yes
2	Ldlr	198	0.761	0.0423	Yes
3	Fosl1	262	0.714	0.0565	Yes
4	Tnf	325	0.675	0.0697	Yes
5	Irs2	555	0.600	0.0724	Yes
6	Bhlhe40	560	0.596	0.0868	Yes
7	Plk2	588	0.591	0.0999	Yes
8	Tnip2	849	0.517	0.0989	Yes
9	Tiparp	871	0.511	0.1103	Yes
10	Fut4	885	0.508	0.1221	Yes
11	Nr4a3	1040	0.478	0.1257	Yes
12	Cebpd	1142	0.462	0.1318	Yes
13	Ifngr2	1240	0.452	0.1378	Yes
14	Relb	1335	0.444	0.1437	Yes
15	Fjx1	1349	0.442	0.1539	Yes
16	Bcl3	1368	0.441	0.1637	Yes
17	Plau	1415	0.437	0.1720	Yes
18	Fosb	1439	0.434	0.1814	Yes
19	Il6st	1503	0.428	0.1886	Yes
20	Pmepa1	1525	0.424	0.1979	Yes
21	Ripk2	1677	0.406	0.1999	Yes
22	Serpinb8	1713	0.403	0.2080	Yes
23	Zc3h12a	1898	0.383	0.2077	Yes
24	Rel	1920	0.381	0.2160	Yes
25	Hbegf	2119	0.359	0.2144	Yes
26	Dram1	2175	0.354	0.2202	Yes
27	Il1b	2476	0.327	0.2125	Yes
28	Gfpt2	2585	0.319	0.2147	Yes
29	Smad3	2626	0.315	0.2203	Yes
30	Lamb3	3102	0.278	0.2023	No
31	Trip10	3389	0.261	0.1937	No
32	Hes1	3390	0.261	0.2001	No
33	Atf3	3486	0.255	0.2014	No
34	Yrdc	3546	0.253	0.2045	No
35	Atp2b1	3708	0.246	0.2021	No
36	Cd80	4020	0.232	0.1916	No
37	Cdkn1a	4196	0.220	0.1878	No
38	Tgif1	4472	0.206	0.1785	No
39	Nfkb2	4705	0.193	0.1711	No
40	Ccrl2	5227	0.163	0.1479	No
41	Csf1	5426	0.153	0.1413	No
42	Sgk1	5556	0.148	0.1381	No
43	Zbtb10	5717	0.140	0.1332	No
44	Vegfa	5866	0.133	0.1287	No
45	Trib1	5960	0.129	0.1270	No
46	Egr3	5961	0.129	0.1302	No
47	Kynu	6001	0.128	0.1313	No
48	Nfkbia	6017	0.128	0.1337	No
49	Jag1	6023	0.128	0.1365	No
50	Phlda2	6183	0.121	0.1312	No
51	Ptger4	6360	0.114	0.1248	No
52	Cd69	6372	0.114	0.1270	No
53	Nfil3	6376	0.113	0.1296	No
54	Btg3	6457	0.110	0.1281	No
55	Pdlim5	6598	0.104	0.1233	No
56	Irf1	6670	0.101	0.1221	No
57	Map2k3	6676	0.101	0.1243	No
58	Tnip1	6747	0.099	0.1231	No
59	Rela	7459	0.072	0.0877	No
60	Gch1	7557	0.068	0.0843	No
61	Dusp1	7610	0.066	0.0832	No
62	Klf4	7714	0.061	0.0793	No
63	Fos	7728	0.060	0.0801	No
64	Ccnl1	7828	0.057	0.0763	No
65	Nfkb1	7832	0.057	0.0775	No
66	Fosl2	7929	0.053	0.0738	No
67	Per1	8025	0.049	0.0701	No
68	Tnfaip2	8060	0.048	0.0695	No
69	Tlr2	8073	0.048	0.0700	No
70	Nr4a2	8302	0.039	0.0591	No
71	B4galt5	8316	0.039	0.0593	No
72	Il7r	8862	0.020	0.0313	No
73	Il6	8941	0.018	0.0277	No
74	Maff	9063	0.014	0.0217	No
75	Sqstm1	9115	0.012	0.0194	No
76	Rcan1	9369	0.003	0.0062	No
77	Id2	9402	0.002	0.0046	No
78	Klf2	9740	-0.004	-0.0129	No
79	Slc16a6	9760	-0.004	-0.0138	No
80	Ets2	9841	-0.007	-0.0178	No
81	Ehd1	10256	-0.022	-0.0389	No
82	Dusp4	10311	-0.024	-0.0411	No
83	Ier5	10379	-0.026	-0.0440	No
84	Plpp3	10711	-0.037	-0.0604	No
85	Nfkbie	10739	-0.039	-0.0608	No
86	Jun	10815	-0.041	-0.0637	No
87	Mcl1	10877	-0.043	-0.0659	No
88	Ier2	10879	-0.043	-0.0649	No
89	Cd44	10947	-0.046	-0.0673	No
90	Ifit2	10999	-0.047	-0.0688	No
91	Btg2	11007	-0.048	-0.0680	No
92	Myc	11047	-0.049	-0.0688	No
93	Stat5a	11165	-0.054	-0.0736	No
94	Klf9	11230	-0.056	-0.0756	No
95	Il15ra	11316	-0.059	-0.0786	No
96	Gadd45b	11418	-0.063	-0.0823	No
97	Klf10	11553	-0.068	-0.0876	No
98	Nfe2l2	11652	-0.072	-0.0910	No
99	Dusp5	11704	-0.074	-0.0918	No
100	Nampt	11720	-0.074	-0.0908	No
101	Tank	11821	-0.078	-0.0941	No
102	B4galt1	11840	-0.079	-0.0931	No
103	Pde4b	12129	-0.088	-0.1060	No
104	Tnfrsf9	12257	-0.093	-0.1104	No
105	Ptpre	12258	-0.093	-0.1081	No
106	Tap1	12292	-0.095	-0.1075	No
107	Dennd5a	12331	-0.097	-0.1071	No
108	Panx1	12365	-0.098	-0.1064	No
109	Ninj1	12385	-0.099	-0.1050	No
110	Gem	12448	-0.101	-0.1057	No
111	Nr4a1	12746	-0.113	-0.1185	No
112	Sphk1	12772	-0.114	-0.1170	No
113	Btg1	12975	-0.121	-0.1246	No
114	Tnfsf9	13394	-0.137	-0.1431	No
115	Cxcl5	13564	-0.144	-0.1484	No
116	Litaf	13583	-0.145	-0.1458	No
117	Rhob	13743	-0.151	-0.1504	No
118	Plek	14080	-0.167	-0.1639	No
119	Klf6	14184	-0.171	-0.1651	No
120	Ifih1	14341	-0.178	-0.1689	No
121	Clcf1	14436	-0.182	-0.1694	No
122	Bcl6	14580	-0.190	-0.1722	No
123	Bmp2	15088	-0.211	-0.1935	No
124	Ppp1r15a	15153	-0.214	-0.1916	No
125	Eif1	15197	-0.217	-0.1886	No
126	Birc3	15214	-0.218	-0.1841	No
127	Cflar	15752	-0.243	-0.2062	No
128	Tnfaip3	15810	-0.246	-0.2031	No
129	Kdm6b	15827	-0.247	-0.1979	No
130	Snn	15906	-0.252	-0.1958	No
131	Rigi	15970	-0.256	-0.1928	No
132	Ier3	16095	-0.262	-0.1929	No
133	Rnf19b	16102	-0.263	-0.1868	No
134	Traf1	16141	-0.265	-0.1823	No
135	Tubb2a	16144	-0.265	-0.1759	No
136	Slc2a6	16267	-0.272	-0.1757	No
137	Il18	16321	-0.274	-0.1717	No
138	Cebpb	16345	-0.276	-0.1662	No
139	Dnajb4	16504	-0.285	-0.1674	No
140	Nfat5	16679	-0.295	-0.1693	No
141	Serpinb2	16727	-0.298	-0.1645	No
142	Pnrc1	16794	-0.302	-0.1605	No
143	Socs3	16878	-0.308	-0.1573	No
144	Plaur	16899	-0.311	-0.1508	No
145	Sod2	17049	-0.319	-0.1507	No
146	Phlda1	17090	-0.322	-0.1450	No
147	Cxcl10	17135	-0.324	-0.1393	No
148	Pfkfb3	17181	-0.326	-0.1337	No
149	Junb	17358	-0.342	-0.1345	No
150	Zfp36	17535	-0.358	-0.1350	No
151	Marcks	17622	-0.364	-0.1306	No
152	Tnfaip8	17675	-0.368	-0.1243	No
153	Slc2a3	17684	-0.369	-0.1156	No
154	Ccl5	17704	-0.372	-0.1075	No
155	Birc2	17737	-0.375	-0.1000	No
156	Tsc22d1	17802	-0.382	-0.0940	No
157	Mxd1	17822	-0.384	-0.0856	No
158	Il1a	18353	-0.443	-0.1025	No
159	Sat1	18354	-0.443	-0.0916	No
160	Icam1	18603	-0.480	-0.0928	No
161	Map3k8	18709	-0.503	-0.0860	No
162	Icosl	18721	-0.506	-0.0742	No
163	Egr1	18766	-0.519	-0.0638	No
164	Gpr183	18893	-0.553	-0.0569	No
165	Gadd45a	18991	-0.595	-0.0474	No
166	Spsb1	19041	-0.616	-0.0349	No
167	Olr1	19052	-0.624	-0.0201	No
168	Dusp2	19114	-0.660	-0.0072	No
169	Abca1	19175	-0.703	0.0069	No