Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | MEP.MEP.mega_Pheno.cls #Group3_versus_Group4.MEP.mega_Pheno.cls #Group3_versus_Group4_repos |
| Phenotype | MEP.mega_Pheno.cls#Group3_versus_Group4_repos |
| Upregulated in class | 2 |
| GeneSet | HALLMARK_TGF_BETA_SIGNALING |
| Enrichment Score (ES) | 0.25381017 |
| Normalized Enrichment Score (NES) | 0.9266937 |
| Nominal p-value | 0.5615866 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.999 |
| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Tjp1 | 182 | 0.783 | 0.0739 | Yes |
| 2 | Ifngr2 | 1240 | 0.452 | 0.0671 | Yes |
| 3 | Cdk9 | 1511 | 0.426 | 0.0984 | Yes |
| 4 | Pmepa1 | 1525 | 0.424 | 0.1429 | Yes |
| 5 | Fkbp1a | 1771 | 0.399 | 0.1726 | Yes |
| 6 | Smad3 | 2626 | 0.315 | 0.1617 | Yes |
| 7 | Skil | 2976 | 0.287 | 0.1742 | Yes |
| 8 | Bmpr1a | 3193 | 0.272 | 0.1919 | Yes |
| 9 | Bcar3 | 3758 | 0.244 | 0.1886 | Yes |
| 10 | Wwtr1 | 3958 | 0.235 | 0.2033 | Yes |
| 11 | Rhoa | 4019 | 0.232 | 0.2248 | Yes |
| 12 | Ctnnb1 | 4368 | 0.213 | 0.2294 | Yes |
| 13 | Tgif1 | 4472 | 0.206 | 0.2460 | Yes |
| 14 | Slc20a1 | 4717 | 0.192 | 0.2538 | Yes |
| 15 | Hipk2 | 5204 | 0.165 | 0.2461 | No |
| 16 | Furin | 5980 | 0.129 | 0.2196 | No |
| 17 | Bmpr2 | 6691 | 0.100 | 0.1934 | No |
| 18 | Ski | 6795 | 0.097 | 0.1984 | No |
| 19 | Tgfbr1 | 7056 | 0.086 | 0.1940 | No |
| 20 | Rab31 | 7274 | 0.078 | 0.1910 | No |
| 21 | Smad1 | 7279 | 0.078 | 0.1991 | No |
| 22 | Cdh1 | 7409 | 0.074 | 0.2002 | No |
| 23 | Hdac1 | 7563 | 0.068 | 0.1995 | No |
| 24 | Ube2d3 | 7947 | 0.053 | 0.1852 | No |
| 25 | Ppm1a | 8198 | 0.043 | 0.1768 | No |
| 26 | Smad6 | 8350 | 0.038 | 0.1730 | No |
| 27 | Acvr1 | 8385 | 0.036 | 0.1751 | No |
| 28 | Sptbn1 | 8611 | 0.029 | 0.1665 | No |
| 29 | Id2 | 9402 | 0.002 | 0.1257 | No |
| 30 | Ncor2 | 10391 | -0.027 | 0.0772 | No |
| 31 | Smad7 | 11334 | -0.060 | 0.0347 | No |
| 32 | Trim33 | 11523 | -0.067 | 0.0320 | No |
| 33 | Klf10 | 11553 | -0.068 | 0.0378 | No |
| 34 | Eng | 12058 | -0.086 | 0.0208 | No |
| 35 | Apc | 12499 | -0.103 | 0.0089 | No |
| 36 | Cdkn1c | 12828 | -0.115 | 0.0042 | No |
| 37 | Arid4b | 13048 | -0.123 | 0.0059 | No |
| 38 | Map3k7 | 13227 | -0.130 | 0.0105 | No |
| 39 | Tgfb1 | 13896 | -0.158 | -0.0074 | No |
| 40 | Smurf1 | 14332 | -0.177 | -0.0112 | No |
| 41 | Xiap | 14706 | -0.196 | -0.0097 | No |
| 42 | Ppp1ca | 15075 | -0.210 | -0.0065 | No |
| 43 | Bmp2 | 15088 | -0.211 | 0.0154 | No |
| 44 | Ppp1r15a | 15153 | -0.214 | 0.0348 | No |
| 45 | Smurf2 | 15933 | -0.254 | 0.0214 | No |
| 46 | Ltbp2 | 16979 | -0.316 | 0.0007 | No |
| 47 | Junb | 17358 | -0.342 | 0.0175 | No |
| 48 | Fnta | 17801 | -0.382 | 0.0352 | No |
| 49 | Thbs1 | 18020 | -0.404 | 0.0668 | No |
