Details for gene set HALLMARK_P53

Table: GSEA Results Summary

Dataset	MEP.MEP.mega_Pheno.cls #Group3_versus_Group4.MEP.mega_Pheno.cls #Group3_versus_Group4_repos
Phenotype	MEP.mega_Pheno.cls#Group3_versus_Group4_repos
Upregulated in class	3
GeneSet	HALLMARK_P53_PATHWAY
Enrichment Score (ES)	-0.2769648
Normalized Enrichment Score (NES)	-1.1010405
Nominal p-value	0.32277226
FDR q-value	1.0
FWER p-Value	0.98

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Trib3	225	0.741	0.0055	No
2	Plk2	588	0.591	0.0004	No
3	Blcap	635	0.582	0.0116	No
4	F2r	711	0.558	0.0207	No
5	Cdkn2a	743	0.548	0.0319	No
6	Gls2	1363	0.441	0.0098	No
7	S100a4	1380	0.440	0.0192	No
8	Elp1	1445	0.433	0.0260	No
9	Ip6k2	1508	0.427	0.0327	No
10	App	1714	0.403	0.0314	No
11	Hbegf	2119	0.359	0.0186	No
12	Dram1	2175	0.354	0.0240	No
13	Trp63	2191	0.352	0.0315	No
14	Cdkn2aip	2265	0.344	0.0357	No
15	Xpc	2268	0.344	0.0436	No
16	Sfn	2279	0.342	0.0511	No
17	Polh	2398	0.333	0.0527	No
18	Baiap2	2400	0.333	0.0604	No
19	Ralgds	2483	0.326	0.0637	No
20	Fgf13	2591	0.319	0.0656	No
21	Upp1	2741	0.307	0.0649	No
22	Ldhb	2780	0.304	0.0700	No
23	Ddit4	3119	0.277	0.0588	No
24	Pmm1	3140	0.276	0.0642	No
25	Rrad	3156	0.275	0.0698	No
26	Atf3	3486	0.255	0.0586	No
27	Tgfa	3663	0.246	0.0551	No
28	Rad9a	3733	0.244	0.0572	No
29	Sp1	3988	0.234	0.0494	No
30	Cd81	4054	0.229	0.0514	No
31	Steap3	4132	0.225	0.0526	No
32	Cdkn1a	4196	0.220	0.0544	No
33	Ctsd	4374	0.213	0.0501	No
34	Tspyl2	4401	0.211	0.0537	No
35	Mknk2	4459	0.208	0.0556	No
36	Abat	4854	0.184	0.0393	No
37	Slc19a2	4935	0.180	0.0393	No
38	Nupr1	4991	0.177	0.0405	No
39	Bax	5107	0.170	0.0385	No
40	Sdc1	5164	0.167	0.0394	No
41	Osgin1	5267	0.161	0.0379	No
42	Cdk5r1	5269	0.161	0.0416	No
43	Plk3	5456	0.152	0.0354	No
44	Ptpn14	5561	0.148	0.0334	No
45	Pvt1	5635	0.144	0.0329	No
46	Csrnp2	5674	0.142	0.0343	No
47	Ccp110	5705	0.141	0.0360	No
48	Slc3a2	6076	0.126	0.0196	No
49	Pidd1	6206	0.120	0.0156	No
50	Triap1	6304	0.116	0.0132	No
51	Def6	6361	0.114	0.0130	No
52	Ddit3	6456	0.110	0.0106	No
53	Ercc5	6630	0.103	0.0040	No
54	Itgb4	6808	0.097	-0.0030	No
55	Zfp36l1	6997	0.088	-0.0108	No
56	Ankra2	7026	0.087	-0.0103	No
57	St14	7068	0.085	-0.0104	No
58	Rps27l	7291	0.077	-0.0202	No
59	Phlda3	7406	0.074	-0.0245	No
60	Rad51c	7550	0.069	-0.0303	No
61	Sesn1	7570	0.068	-0.0298	No
62	Dcxr	7616	0.065	-0.0306	No
63	Klf4	7714	0.061	-0.0342	No
64	Fos	7728	0.060	-0.0335	No
65	Dgka	7766	0.059	-0.0341	No
66	Casp1	7865	0.056	-0.0379	No
67	Aen	7921	0.053	-0.0395	No
68	Socs1	8008	0.050	-0.0428	No
69	Ccng1	8247	0.041	-0.0543	No
70	Tm7sf3	8476	0.033	-0.0655	No
71	Tob1	8816	0.021	-0.0827	No
72	Fuca1	8915	0.019	-0.0874	No
73	Pcna	9042	0.015	-0.0936	No
74	Cd82	9089	0.013	-0.0957	No
75	Gm2a	9093	0.013	-0.0956	No
76	Hdac3	9098	0.013	-0.0955	No
77	Mxd4	9467	0.000	-0.1147	No
78	Rb1	9770	-0.005	-0.1304	No
79	Fbxw7	9878	-0.009	-0.1358	No
80	Ccnd2	9919	-0.010	-0.1377	No
81	Zmat3	10052	-0.014	-0.1443	No
82	Hspa4l	10235	-0.021	-0.1533	No
83	Ier5	10379	-0.026	-0.1602	No
84	Jag2	10689	-0.036	-0.1755	No
85	Bak1	10743	-0.039	-0.1773	No
86	Jun	10815	-0.041	-0.1801	No
87	Apaf1	10927	-0.045	-0.1848	No
88	Epha2	10941	-0.045	-0.1845	No
89	Btg2	11007	-0.048	-0.1867	No
90	Rchy1	11049	-0.049	-0.1877	No
91	Retsat	11201	-0.055	-0.1943	No
92	Zbtb16	11222	-0.056	-0.1941	No
93	Cdh13	11443	-0.064	-0.2041	No
94	Traf4	11562	-0.069	-0.2087	No
95	Foxo3	11891	-0.081	-0.2239	No
96	Vwa5a	12215	-0.092	-0.2387	No
97	Slc35d1	12223	-0.092	-0.2369	No
98	Ptpre	12258	-0.093	-0.2365	No
99	Wwp1	12267	-0.094	-0.2347	No
100	Ccnk	12277	-0.095	-0.2330	No
101	Tap1	12292	-0.095	-0.2315	No
102	Irag2	12305	-0.096	-0.2299	No
103	Ninj1	12385	-0.099	-0.2317	No
104	Tprkb	12561	-0.106	-0.2384	No
105	Perp	12565	-0.106	-0.2361	No
106	Hmox1	12732	-0.112	-0.2422	No
107	Sphk1	12772	-0.114	-0.2415	No
108	Ephx1	12795	-0.115	-0.2400	No
109	Trp53	12855	-0.116	-0.2404	No
110	Zfp365	12900	-0.118	-0.2399	No
111	Btg1	12975	-0.121	-0.2410	No
112	Tax1bp3	13003	-0.122	-0.2395	No
113	Kif13b	13045	-0.123	-0.2388	No
114	Fam162a	13128	-0.126	-0.2402	No
115	Hras	13159	-0.127	-0.2388	No
116	Pom121	13167	-0.127	-0.2362	No
117	Tpd52l1	13300	-0.133	-0.2400	No
118	Irak1	13312	-0.133	-0.2374	No
119	Tnfsf9	13394	-0.137	-0.2385	No
120	Eps8l2	13612	-0.146	-0.2464	No
121	Hint1	13627	-0.146	-0.2438	No
122	Pitpnc1	13646	-0.147	-0.2413	No
123	Nol8	13699	-0.149	-0.2405	No
124	Sertad3	13817	-0.154	-0.2430	No
125	Tgfb1	13896	-0.158	-0.2434	No
126	Rpl36	14360	-0.179	-0.2635	No
127	Ddb2	14418	-0.181	-0.2622	No
128	Rrp8	14423	-0.182	-0.2582	No
129	Vamp8	14529	-0.187	-0.2593	No
130	Rack1	14618	-0.191	-0.2595	No
131	Rap2b	14721	-0.197	-0.2602	No
132	Ppm1d	14785	-0.200	-0.2588	No
133	Bmp2	15088	-0.211	-0.2697	No
134	Cyfip2	15124	-0.213	-0.2666	No
135	Acvr1b	15125	-0.213	-0.2616	No
136	Ppp1r15a	15153	-0.214	-0.2580	No
137	Prmt2	15301	-0.222	-0.2605	No
138	Nudt15	15448	-0.229	-0.2628	No
139	Notch1	15718	-0.242	-0.2712	Yes
140	Fdxr	15829	-0.247	-0.2712	Yes
141	Wrap73	15886	-0.252	-0.2683	Yes
142	Tcn2	15967	-0.256	-0.2665	Yes
143	Cebpa	16013	-0.257	-0.2628	Yes
144	Ier3	16095	-0.262	-0.2609	Yes
145	Rnf19b	16102	-0.263	-0.2551	Yes
146	Cgrrf1	16143	-0.265	-0.2510	Yes
147	Sec61a1	16239	-0.270	-0.2497	Yes
148	Stom	16270	-0.272	-0.2449	Yes
149	Mapkapk3	16355	-0.277	-0.2428	Yes
150	S100a10	16438	-0.282	-0.2406	Yes
151	Rps12	16538	-0.287	-0.2390	Yes
152	Fas	16633	-0.292	-0.2371	Yes
153	Mdm2	16787	-0.302	-0.2381	Yes
154	H1f2	16803	-0.303	-0.2318	Yes
155	Hexim1	16884	-0.309	-0.2288	Yes
156	Rxra	16906	-0.311	-0.2226	Yes
157	Ada	16940	-0.313	-0.2170	Yes
158	Txnip	17087	-0.321	-0.2172	Yes
159	Plxnb2	17125	-0.324	-0.2115	Yes
160	Coq8a	17264	-0.333	-0.2110	Yes
161	Rpl18	17374	-0.343	-0.2087	Yes
162	Rab40c	17487	-0.354	-0.2063	Yes
163	Klk8	17495	-0.355	-0.1983	Yes
164	Abhd4	17604	-0.362	-0.1955	Yes
165	Rhbdf2	17606	-0.362	-0.1871	Yes
166	Ndrg1	17671	-0.368	-0.1819	Yes
167	Procr	17674	-0.368	-0.1734	Yes
168	Tsc22d1	17802	-0.382	-0.1711	Yes
169	Mxd1	17822	-0.384	-0.1632	Yes
170	H2aj	18012	-0.403	-0.1636	Yes
171	Pdgfa	18026	-0.404	-0.1549	Yes
172	Il1a	18353	-0.443	-0.1616	Yes
173	Sat1	18354	-0.443	-0.1513	Yes
174	Vdr	18394	-0.449	-0.1428	Yes
175	Abcc5	18673	-0.493	-0.1459	Yes
176	Slc7a11	18681	-0.496	-0.1347	Yes
177	Ak1	18787	-0.523	-0.1279	Yes
178	Prkab1	18826	-0.535	-0.1174	Yes
179	Dnttip2	18857	-0.543	-0.1063	Yes
180	H2ac25	18859	-0.544	-0.0937	Yes
181	Ctsf	18954	-0.577	-0.0851	Yes
182	Gadd45a	18991	-0.595	-0.0731	Yes
183	Trafd1	19053	-0.624	-0.0617	Yes
184	Ccnd3	19192	-0.729	-0.0519	Yes
185	Ei24	19221	-0.771	-0.0354	Yes
186	Ifi30	19249	-0.818	-0.0177	Yes
187	Iscu	19277	-0.887	0.0016	Yes