| Dataset | MEP.MEP.mega_Pheno.cls #Group3_versus_Group4.MEP.mega_Pheno.cls #Group3_versus_Group4_repos |
| Phenotype | MEP.mega_Pheno.cls#Group3_versus_Group4_repos |
| Upregulated in class | 3 |
| GeneSet | HALLMARK_OXIDATIVE_PHOSPHORYLATION |
| Enrichment Score (ES) | -0.2900145 |
| Normalized Enrichment Score (NES) | -1.0713862 |
| Nominal p-value | 0.33534136 |
| FDR q-value | 0.8808725 |
| FWER p-Value | 0.983 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Ndufa7 | 1574 | 0.420 | -0.0700 | No |
| 2 | Cox11 | 1824 | 0.394 | -0.0715 | No |
| 3 | Mrps22 | 1829 | 0.393 | -0.0602 | No |
| 4 | Uqcrb | 1852 | 0.390 | -0.0500 | No |
| 5 | Ndufs2 | 2021 | 0.370 | -0.0479 | No |
| 6 | Fdx1 | 2076 | 0.363 | -0.0401 | No |
| 7 | Immt | 2241 | 0.347 | -0.0386 | No |
| 8 | Ndufc2 | 2419 | 0.331 | -0.0381 | No |
| 9 | Ndufc1 | 2617 | 0.316 | -0.0392 | No |
| 10 | Mtx2 | 2688 | 0.311 | -0.0338 | No |
| 11 | Idh3b | 2720 | 0.309 | -0.0264 | No |
| 12 | Hccs | 2752 | 0.305 | -0.0191 | No |
| 13 | Ldhb | 2780 | 0.304 | -0.0116 | No |
| 14 | Ndufa9 | 2810 | 0.301 | -0.0043 | No |
| 15 | Bckdha | 3097 | 0.279 | -0.0111 | No |
| 16 | Oat | 3106 | 0.278 | -0.0034 | No |
| 17 | Uqcrc2 | 3177 | 0.273 | 0.0009 | No |
| 18 | Timm17a | 3298 | 0.269 | 0.0025 | No |
| 19 | Sdhd | 3406 | 0.260 | 0.0045 | No |
| 20 | Pdk4 | 3530 | 0.255 | 0.0055 | No |
| 21 | Timm9 | 3726 | 0.245 | 0.0025 | No |
| 22 | Mrpl35 | 3727 | 0.245 | 0.0096 | No |
| 23 | Cox10 | 3837 | 0.242 | 0.0110 | No |
| 24 | Nqo2 | 3941 | 0.236 | 0.0125 | No |
| 25 | Pmpca | 4111 | 0.226 | 0.0103 | No |
| 26 | Acaa2 | 4149 | 0.224 | 0.0149 | No |
| 27 | Dlst | 4383 | 0.212 | 0.0090 | No |
| 28 | Pdha1 | 4440 | 0.209 | 0.0121 | No |
| 29 | Vdac2 | 4481 | 0.205 | 0.0160 | No |
| 30 | Atp6v1h | 4745 | 0.191 | 0.0079 | No |
| 31 | Ndufb6 | 4918 | 0.181 | 0.0042 | No |
| 32 | Cox7c | 4958 | 0.179 | 0.0074 | No |
| 33 | Alas1 | 5105 | 0.170 | 0.0047 | No |
| 34 | Bax | 5107 | 0.170 | 0.0096 | No |
| 35 | Aldh6a1 | 5236 | 0.163 | 0.0077 | No |
| 36 | Ndufs1 | 5249 | 0.162 | 0.0118 | No |
| 37 | Mrps11 | 5313 | 0.159 | 0.0131 | No |
| 38 | Pdp1 | 5327 | 0.158 | 0.0171 | No |
| 39 | Lrpprc | 5798 | 0.136 | -0.0035 | No |
| 40 | Sdha | 5860 | 0.134 | -0.0028 | No |
| 41 | Glud1 | 6162 | 0.122 | -0.0150 | No |
| 42 | Rhot2 | 6188 | 0.121 | -0.0128 | No |
| 43 | Phb2 | 6265 | 0.117 | -0.0133 | No |
| 44 | Slc25a3 | 6352 | 0.114 | -0.0145 | No |
| 45 | Cs | 6398 | 0.112 | -0.0135 | No |
| 46 | Uqcrq | 6537 | 0.107 | -0.0176 | No |
| 47 | Atp6v1c1 | 6651 | 0.102 | -0.0206 | No |
| 48 | Gpi1 | 6669 | 0.101 | -0.0185 | No |
| 49 | Slc25a5 | 6688 | 0.100 | -0.0165 | No |
| 50 | Hspa9 | 6828 | 0.096 | -0.0210 | No |
| 51 | Aco2 | 6917 | 0.091 | -0.0229 | No |
| 52 | Got2 | 6958 | 0.090 | -0.0224 | No |
| 53 | Afg3l2 | 7021 | 0.087 | -0.0231 | No |
| 54 | Mrpl15 | 7060 | 0.085 | -0.0226 | No |
| 55 | Nnt | 7095 | 0.084 | -0.0219 | No |
| 56 | Cox5b | 7303 | 0.077 | -0.0304 | No |
| 57 | Ndufs4 | 7304 | 0.077 | -0.0282 | No |
| 58 | Uqcrfs1 | 7306 | 0.077 | -0.0260 | No |
| 59 | Uqcr10 | 7549 | 0.069 | -0.0366 | No |
| 60 | Hadha | 7574 | 0.068 | -0.0359 | No |
| 61 | Acadsb | 7689 | 0.062 | -0.0401 | No |
| 62 | Uqcrc1 | 7877 | 0.055 | -0.0482 | No |
| 63 | Ndufs6 | 7939 | 0.053 | -0.0499 | No |
| 64 | Oxa1l | 8020 | 0.049 | -0.0526 | No |
| 65 | Idh2 | 8136 | 0.045 | -0.0573 | No |
| 66 | Atp6v0e | 8179 | 0.044 | -0.0582 | No |
| 67 | Cox4i1 | 8209 | 0.043 | -0.0585 | No |
| 68 | Atp6v0b | 8278 | 0.040 | -0.0609 | No |
| 69 | Acat1 | 8281 | 0.040 | -0.0598 | No |
| 70 | Sdhc | 8284 | 0.040 | -0.0587 | No |
| 71 | Ndufb3 | 8317 | 0.039 | -0.0593 | No |
| 72 | Mpc1 | 8353 | 0.038 | -0.0600 | No |
| 73 | Ndufa4 | 8373 | 0.037 | -0.0599 | No |
| 74 | Tomm70a | 8399 | 0.036 | -0.0602 | No |
| 75 | Dlat | 8441 | 0.034 | -0.0613 | No |
| 76 | Atp5pb | 8524 | 0.031 | -0.0647 | No |
| 77 | Aifm1 | 8526 | 0.031 | -0.0638 | No |
| 78 | Uqcr11 | 8577 | 0.030 | -0.0656 | No |
| 79 | Hadhb | 8909 | 0.020 | -0.0823 | No |
| 80 | Mrps30 | 8918 | 0.019 | -0.0822 | No |
| 81 | Eci1 | 8922 | 0.019 | -0.0818 | No |
| 82 | Mrpl11 | 9009 | 0.016 | -0.0858 | No |
| 83 | Cyc1 | 9069 | 0.014 | -0.0885 | No |
| 84 | Etfa | 9096 | 0.013 | -0.0895 | No |
| 85 | Echs1 | 9124 | 0.012 | -0.0905 | No |
| 86 | Atp1b1 | 9194 | 0.009 | -0.0939 | No |
| 87 | Atp6ap1 | 9256 | 0.007 | -0.0968 | No |
| 88 | Ndufb8 | 9397 | 0.002 | -0.1041 | No |
| 89 | Mdh1 | 9452 | 0.001 | -0.1069 | No |
| 90 | Timm50 | 9717 | -0.003 | -0.1206 | No |
| 91 | Cox7a2 | 9825 | -0.007 | -0.1260 | No |
| 92 | Surf1 | 9826 | -0.007 | -0.1258 | No |
| 93 | Rhot1 | 9910 | -0.010 | -0.1298 | No |
| 94 | Dld | 9932 | -0.010 | -0.1306 | No |
| 95 | Acaa1a | 10013 | -0.013 | -0.1344 | No |
| 96 | Por | 10166 | -0.018 | -0.1419 | No |
| 97 | Opa1 | 10210 | -0.020 | -0.1435 | No |
| 98 | Polr2f | 10234 | -0.021 | -0.1441 | No |
| 99 | Casp7 | 10252 | -0.022 | -0.1444 | No |
| 100 | Mrpl34 | 10427 | -0.028 | -0.1527 | No |
| 101 | Acadvl | 10658 | -0.035 | -0.1636 | No |
| 102 | Ndufa2 | 10735 | -0.038 | -0.1665 | No |
| 103 | Ogdh | 10839 | -0.042 | -0.1707 | No |
| 104 | Cox15 | 10897 | -0.044 | -0.1724 | No |
| 105 | Ndufv1 | 10964 | -0.046 | -0.1745 | No |
| 106 | Suclg1 | 10995 | -0.047 | -0.1747 | No |
| 107 | Sucla2 | 11129 | -0.052 | -0.1801 | No |
| 108 | Mrps15 | 11144 | -0.053 | -0.1793 | No |
| 109 | Retsat | 11201 | -0.055 | -0.1806 | No |
| 110 | Ndufa3 | 11241 | -0.056 | -0.1810 | No |
| 111 | Ndufa5 | 11441 | -0.064 | -0.1895 | No |
| 112 | Abcb7 | 11699 | -0.074 | -0.2008 | No |
| 113 | Atp6v1f | 11713 | -0.074 | -0.1993 | No |
| 114 | Ndufv2 | 11874 | -0.080 | -0.2053 | No |
| 115 | Ldha | 12034 | -0.085 | -0.2111 | No |
| 116 | Ndufs7 | 12077 | -0.087 | -0.2108 | No |
| 117 | Cox6b1 | 12103 | -0.087 | -0.2096 | No |
| 118 | Mtrf1 | 12181 | -0.091 | -0.2109 | No |
| 119 | Gpx4 | 12324 | -0.097 | -0.2155 | No |
| 120 | Mgst3 | 12487 | -0.103 | -0.2210 | No |
| 121 | Ndufa8 | 12552 | -0.105 | -0.2213 | No |
| 122 | Sdhb | 12558 | -0.105 | -0.2184 | No |
| 123 | Acadm | 12569 | -0.106 | -0.2159 | No |
| 124 | Mrps12 | 12622 | -0.108 | -0.2154 | No |
| 125 | Ndufa1 | 12669 | -0.110 | -0.2146 | No |
| 126 | Fxn | 12815 | -0.115 | -0.2189 | No |
| 127 | Cox17 | 12818 | -0.115 | -0.2156 | No |
| 128 | Idh3a | 12905 | -0.118 | -0.2166 | No |
| 129 | Etfdh | 12954 | -0.120 | -0.2156 | No |
| 130 | Hsd17b10 | 12993 | -0.121 | -0.2141 | No |
| 131 | Fh1 | 13320 | -0.133 | -0.2272 | No |
| 132 | Vdac1 | 13471 | -0.140 | -0.2310 | No |
| 133 | Mtrr | 13648 | -0.147 | -0.2359 | No |
| 134 | Supv3l1 | 14070 | -0.166 | -0.2530 | No |
| 135 | Idh1 | 14111 | -0.168 | -0.2502 | No |
| 136 | Etfb | 14131 | -0.169 | -0.2463 | No |
| 137 | Decr1 | 14290 | -0.175 | -0.2494 | No |
| 138 | Uqcrh | 14319 | -0.177 | -0.2457 | No |
| 139 | Cox8a | 14664 | -0.194 | -0.2580 | No |
| 140 | Bdh2 | 14786 | -0.200 | -0.2585 | No |
| 141 | Ndufa6 | 15040 | -0.208 | -0.2656 | No |
| 142 | Ndufs8 | 15044 | -0.209 | -0.2597 | No |
| 143 | Atp6v1g1 | 15061 | -0.210 | -0.2544 | No |
| 144 | Mfn2 | 15079 | -0.210 | -0.2491 | No |
| 145 | Pdhx | 15158 | -0.215 | -0.2469 | No |
| 146 | Vdac3 | 15688 | -0.241 | -0.2676 | No |
| 147 | Ech1 | 15728 | -0.242 | -0.2625 | No |
| 148 | Cox7b | 16255 | -0.271 | -0.2821 | Yes |
| 149 | Idh3g | 16340 | -0.275 | -0.2784 | Yes |
| 150 | Prdx3 | 16349 | -0.276 | -0.2708 | Yes |
| 151 | Timm13 | 16393 | -0.279 | -0.2649 | Yes |
| 152 | Cox6a1 | 16599 | -0.290 | -0.2671 | Yes |
| 153 | Slc25a4 | 16668 | -0.294 | -0.2621 | Yes |
| 154 | Mdh2 | 16730 | -0.299 | -0.2565 | Yes |
| 155 | Slc25a20 | 16807 | -0.303 | -0.2516 | Yes |
| 156 | Slc25a11 | 17072 | -0.321 | -0.2561 | Yes |
| 157 | Timm8b | 17086 | -0.321 | -0.2473 | Yes |
| 158 | Cox6c | 17229 | -0.331 | -0.2451 | Yes |
| 159 | Cox5a | 17486 | -0.354 | -0.2481 | Yes |
| 160 | Cyb5a | 17670 | -0.368 | -0.2469 | Yes |
| 161 | Tcirg1 | 17730 | -0.375 | -0.2391 | Yes |
| 162 | Ndufb5 | 17754 | -0.377 | -0.2292 | Yes |
| 163 | Atp6v1e1 | 17842 | -0.386 | -0.2225 | Yes |
| 164 | Ndufb2 | 17917 | -0.394 | -0.2149 | Yes |
| 165 | Cyb5r3 | 18393 | -0.448 | -0.2266 | Yes |
| 166 | Htra2 | 18475 | -0.461 | -0.2173 | Yes |
| 167 | Ndufab1 | 18597 | -0.479 | -0.2097 | Yes |
| 168 | Grpel1 | 18606 | -0.481 | -0.1960 | Yes |
| 169 | Cox7a2l | 18745 | -0.513 | -0.1882 | Yes |
| 170 | Timm10 | 18788 | -0.523 | -0.1751 | Yes |
| 171 | Cpt1a | 18870 | -0.547 | -0.1634 | Yes |
| 172 | Atp6v1d | 18888 | -0.550 | -0.1482 | Yes |
| 173 | Tomm22 | 18931 | -0.569 | -0.1337 | Yes |
| 174 | Slc25a12 | 19039 | -0.615 | -0.1213 | Yes |
| 175 | Phyh | 19051 | -0.623 | -0.1037 | Yes |
| 176 | Atp6v0c | 19117 | -0.663 | -0.0877 | Yes |
| 177 | Pdhb | 19120 | -0.664 | -0.0684 | Yes |
| 178 | Ndufb7 | 19130 | -0.673 | -0.0492 | Yes |
| 179 | Iscu | 19277 | -0.887 | -0.0309 | Yes |
| 180 | Ndufs3 | 19301 | -1.108 | 0.0003 | Yes |

