Details for gene set HALLMARK_KRAS_SIGNALING

Table: GSEA Results Summary

Dataset	MEP.MEP.mega_Pheno.cls #Group3_versus_Group4.MEP.mega_Pheno.cls #Group3_versus_Group4_repos
Phenotype	MEP.mega_Pheno.cls#Group3_versus_Group4_repos
Upregulated in class	2
GeneSet	HALLMARK_KRAS_SIGNALING_UP
Enrichment Score (ES)	0.31770205
Normalized Enrichment Score (NES)	1.3589069
Nominal p-value	0.062111802
FDR q-value	0.7257151
FWER p-Value	0.686

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Dcbld2	50	0.992	0.0250	Yes
2	Abcb1a	112	0.849	0.0455	Yes
3	Dusp6	208	0.755	0.0615	Yes
4	Btbd3	264	0.712	0.0785	Yes
5	Cbx8	270	0.708	0.0979	Yes
6	Mycn	336	0.670	0.1132	Yes
7	Kif5c	367	0.652	0.1298	Yes
8	Hdac9	415	0.635	0.1450	Yes
9	Btc	777	0.536	0.1411	Yes
10	Il10ra	947	0.496	0.1461	Yes
11	Ero1a	981	0.489	0.1580	Yes
12	Reln	992	0.486	0.1710	Yes
13	Mafb	1234	0.452	0.1710	Yes
14	Galnt3	1261	0.449	0.1821	Yes
15	Etv1	1361	0.441	0.1893	Yes
16	Plau	1415	0.437	0.1987	Yes
17	Aldh1a3	1422	0.437	0.2105	Yes
18	Cfb	1622	0.412	0.2116	Yes
19	Gabra3	1746	0.400	0.2163	Yes
20	Lat2	1776	0.398	0.2259	Yes
21	Nin	2023	0.370	0.2233	Yes
22	Trib2	2046	0.367	0.2324	Yes
23	Hbegf	2119	0.359	0.2387	Yes
24	Mtmr10	2128	0.359	0.2482	Yes
25	Prdm1	2154	0.356	0.2568	Yes
26	Prelid3b	2231	0.348	0.2626	Yes
27	Mmp11	2260	0.345	0.2707	Yes
28	Irf8	2339	0.337	0.2760	Yes
29	Il1b	2476	0.327	0.2780	Yes
30	Zfp639	2524	0.323	0.2846	Yes
31	Akap12	2536	0.323	0.2930	Yes
32	Gfpt2	2585	0.319	0.2994	Yes
33	Il2rg	2658	0.313	0.3043	Yes
34	Adgra2	2686	0.311	0.3115	Yes
35	St6gal1	2733	0.307	0.3177	Yes
36	Epb41l3	2940	0.290	0.3150	No
37	Wdr33	3305	0.269	0.3035	No
38	Yrdc	3546	0.253	0.2980	No
39	Plvap	3645	0.247	0.2998	No
40	Atg10	3991	0.233	0.2883	No
41	Ctss	4139	0.224	0.2869	No
42	Spry2	4213	0.219	0.2892	No
43	Fbxo4	4269	0.216	0.2923	No
44	Lcp1	4494	0.205	0.2863	No
45	Map4k1	4568	0.201	0.2881	No
46	Nrp1	4587	0.199	0.2927	No
47	Scn1b	4620	0.198	0.2965	No
48	Adgrl4	4640	0.197	0.3010	No
49	Etv5	4871	0.183	0.2941	No
50	Il1rl2	5259	0.161	0.2784	No
51	Prkg2	5417	0.153	0.2745	No
52	Nr1h4	5461	0.152	0.2765	No
53	Tor1aip2	5654	0.143	0.2705	No
54	H2bc3	5826	0.135	0.2653	No
55	Tspan13	5844	0.134	0.2681	No
56	Trib1	5960	0.129	0.2657	No
57	Evi5	6075	0.126	0.2633	No
58	Spon1	6088	0.125	0.2662	No
59	Pdcd1lg2	6155	0.122	0.2661	No
60	Flt4	6159	0.122	0.2694	No
61	Ccser2	6425	0.111	0.2586	No
62	Bpgm	6625	0.103	0.2511	No
63	Usp12	6694	0.100	0.2503	No
64	Ammecr1	6845	0.095	0.2452	No
65	Etv4	7048	0.086	0.2370	No
66	Klf4	7714	0.061	0.2040	No
67	Avl9	7851	0.056	0.1985	No
68	Cxcr4	8220	0.042	0.1804	No
69	Arg1	8320	0.039	0.1763	No
70	Zfp277	8370	0.037	0.1748	No
71	Map7	8425	0.035	0.1730	No
72	Dock2	8481	0.033	0.1710	No
73	Fcer1g	8736	0.024	0.1584	No
74	Tnfrsf1b	8764	0.023	0.1577	No
75	Map3k1	8826	0.021	0.1551	No
76	Il7r	8862	0.020	0.1538	No
77	Fuca1	8915	0.019	0.1516	No
78	Cab39l	8990	0.017	0.1482	No
79	Car2	9057	0.014	0.1452	No
80	Id2	9402	0.002	0.1273	No
81	Ptprr	9470	0.000	0.1238	No
82	Plek2	9475	0.000	0.1236	No
83	Ccnd2	9919	-0.010	0.1007	No
84	Gucy1a1	9962	-0.012	0.0989	No
85	Sdccag8	10318	-0.024	0.0810	No
86	Kcnn4	10417	-0.027	0.0767	No
87	Adam17	11039	-0.049	0.0456	No
88	Strn	11155	-0.054	0.0411	No
89	Gypc	11424	-0.064	0.0289	No
90	Cd37	11921	-0.082	0.0053	No
91	Eng	12058	-0.086	0.0006	No
92	Vwa5a	12215	-0.092	-0.0050	No
93	Cdadc1	12246	-0.093	-0.0040	No
94	Ly96	12298	-0.095	-0.0040	No
95	Akt2	12474	-0.102	-0.0103	No
96	Angptl4	12545	-0.105	-0.0110	No
97	Ikzf1	12849	-0.116	-0.0236	No
98	Itgbl1	13109	-0.126	-0.0336	No
99	Ptbp2	13189	-0.128	-0.0341	No
100	Cbl	13361	-0.136	-0.0393	No
101	Rbm4	13675	-0.148	-0.0515	No
102	Tmem176a	13923	-0.159	-0.0600	No
103	Cmklr1	14193	-0.171	-0.0692	No
104	F13a1	14303	-0.176	-0.0700	No
105	Nr0b2	14394	-0.180	-0.0697	No
106	Ptcd2	14499	-0.185	-0.0700	No
107	Glrx	14655	-0.193	-0.0727	No
108	Aldh1a2	14676	-0.194	-0.0683	No
109	Bmp2	15088	-0.211	-0.0839	No
110	Ppp1r15a	15153	-0.214	-0.0813	No
111	Birc3	15214	-0.218	-0.0783	No
112	Ano1	15315	-0.222	-0.0773	No
113	Gadd45g	15378	-0.225	-0.0743	No
114	Psmb8	15445	-0.229	-0.0714	No
115	Rabgap1l	15486	-0.231	-0.0670	No
116	Scg5	15589	-0.236	-0.0658	No
117	Itgb2	15619	-0.238	-0.0607	No
118	Slpi	15773	-0.244	-0.0619	No
119	Tnfaip3	15810	-0.246	-0.0569	No
120	Dnmbp	15815	-0.246	-0.0502	No
121	Ets1	16127	-0.264	-0.0591	No
122	Tmem176b	16135	-0.265	-0.0521	No
123	Traf1	16141	-0.265	-0.0450	No
124	Tmem158	16312	-0.274	-0.0463	No
125	Hsd11b1	16403	-0.279	-0.0432	No
126	Ank	16495	-0.285	-0.0400	No
127	Wnt7a	16517	-0.286	-0.0331	No
128	Crot	16617	-0.291	-0.0302	No
129	Ephb2	16723	-0.298	-0.0274	No
130	Plaur	16899	-0.311	-0.0278	No
131	Cbr4	16925	-0.312	-0.0204	No
132	Tfpi	16962	-0.315	-0.0136	No
133	Cxcl10	17135	-0.324	-0.0135	No
134	Csf2ra	17209	-0.329	-0.0082	No
135	Mmd	17365	-0.343	-0.0067	No
136	Adam8	17451	-0.350	-0.0014	No
137	Jup	17493	-0.354	0.0063	No
138	Gprc5b	17919	-0.394	-0.0049	No
139	Gng11	17982	-0.399	0.0030	No
140	Laptm5	17998	-0.402	0.0134	No
141	Ppbp	18004	-0.402	0.0243	No
142	Itga2	18485	-0.463	0.0122	No
143	Pecam1	18647	-0.489	0.0174	No
144	Satb1	19028	-0.610	0.0146	No