Details for gene set HALLMARK_HEME

Table: GSEA Results Summary

Dataset	MEP.MEP.mega_Pheno.cls #Group3_versus_Group4.MEP.mega_Pheno.cls #Group3_versus_Group4_repos
Phenotype	MEP.mega_Pheno.cls#Group3_versus_Group4_repos
Upregulated in class	3
GeneSet	HALLMARK_HEME_METABOLISM
Enrichment Score (ES)	-0.32832715
Normalized Enrichment Score (NES)	-1.2774082
Nominal p-value	0.08806262
FDR q-value	1.0
FWER p-Value	0.815

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Acsl6	359	0.657	-0.0017	No
2	Bmp2k	820	0.524	-0.0122	No
3	Endod1	882	0.509	-0.0022	No
4	Ubac1	1134	0.465	-0.0032	No
5	Mospd1	1359	0.442	-0.0035	No
6	Add2	1414	0.437	0.0050	No
7	Ank1	1514	0.425	0.0109	No
8	Minpp1	1615	0.412	0.0163	No
9	Pcx	2001	0.373	0.0059	No
10	Slc25a38	2394	0.333	-0.0060	No
11	Osbp2	2406	0.333	0.0021	No
12	Tmem9b	2746	0.306	-0.0077	No
13	Slc6a9	2831	0.299	-0.0043	No
14	Ctsb	2995	0.287	-0.0054	No
15	Glrx5	3145	0.275	-0.0061	No
16	Asns	3186	0.273	-0.0011	No
17	Spta1	3370	0.263	-0.0038	No
18	Abcg2	3411	0.260	0.0008	No
19	P4ha2	3480	0.255	0.0039	No
20	Hebp1	3592	0.250	0.0046	No
21	Cdr2	3617	0.249	0.0097	No
22	Nfe2l1	3644	0.247	0.0148	No
23	Psmd9	3749	0.244	0.0157	No
24	Dmtn	4022	0.232	0.0075	No
25	Dcun1d1	4528	0.203	-0.0137	No
26	Trak2	4531	0.203	-0.0085	No
27	Synj1	4627	0.198	-0.0083	No
28	Tent5c	4666	0.196	-0.0052	No
29	Ncoa4	5009	0.176	-0.0186	No
30	Aldh6a1	5236	0.163	-0.0262	No
31	Gmps	5242	0.163	-0.0222	No
32	Kdm7a	5329	0.158	-0.0226	No
33	Fbxo34	5414	0.154	-0.0230	No
34	Slc11a2	5455	0.152	-0.0212	No
35	Gclc	5557	0.148	-0.0226	No
36	Cdc27	5761	0.138	-0.0296	No
37	Klf1	6027	0.128	-0.0402	No
38	E2f2	6086	0.125	-0.0400	No
39	Ell2	6191	0.121	-0.0423	No
40	Hagh	6236	0.118	-0.0415	No
41	Car1	6429	0.111	-0.0487	No
42	Bpgm	6625	0.103	-0.0562	No
43	Map2k3	6676	0.101	-0.0562	No
44	Sidt2	6942	0.090	-0.0677	No
45	Rhag	6998	0.088	-0.0683	No
46	Aldh1l1	7057	0.085	-0.0691	No
47	Nnt	7095	0.084	-0.0689	No
48	Bnip3l	7385	0.074	-0.0821	No
49	Lmo2	7393	0.074	-0.0805	No
50	Hmbs	7523	0.070	-0.0854	No
51	Trim58	7527	0.070	-0.0838	No
52	Sec14l1	7532	0.069	-0.0822	No
53	Picalm	7613	0.066	-0.0847	No
54	Slc4a1	7721	0.061	-0.0887	No
55	Nr3c1	7777	0.059	-0.0901	No
56	Rcl1	7894	0.055	-0.0947	No
57	Mark3	8042	0.049	-0.1011	No
58	Ezh1	8070	0.048	-0.1013	No
59	Usp15	8129	0.045	-0.1032	No
60	Dcaf11	8308	0.039	-0.1114	No
61	Ermap	8769	0.023	-0.1349	No
62	Agpat4	9008	0.016	-0.1469	No
63	Foxj2	9030	0.015	-0.1476	No
64	Car2	9057	0.014	-0.1486	No
65	Tcea1	9081	0.013	-0.1495	No
66	Tfrc	9169	0.010	-0.1538	No
67	Rnf19a	9270	0.007	-0.1588	No
68	Mocos	9277	0.007	-0.1590	No
69	Xpo7	9646	-0.001	-0.1782	No
70	Slc2a1	9669	-0.002	-0.1793	No
71	Nudt4	9733	-0.004	-0.1825	No
72	Nek7	9906	-0.009	-0.1912	No
73	Ppox	9953	-0.011	-0.1933	No
74	Slc10a3	10091	-0.016	-0.2001	No
75	Pigq	10199	-0.020	-0.2052	No
76	H1f0	10310	-0.024	-0.2103	No
77	Cpox	10345	-0.024	-0.2115	No
78	Rnf123	10356	-0.025	-0.2113	No
79	Dcaf10	10581	-0.032	-0.2222	No
80	Urod	10751	-0.039	-0.2300	No
81	Btrc	10787	-0.041	-0.2308	No
82	Tspo2	10817	-0.041	-0.2313	No
83	Gapvd1	10900	-0.044	-0.2344	No
84	Blvrb	10981	-0.047	-0.2374	No
85	Btg2	11007	-0.048	-0.2374	No
86	Fbxo7	11074	-0.050	-0.2396	No
87	Lpin2	11093	-0.051	-0.2392	No
88	Rbm5	11359	-0.061	-0.2515	No
89	Cast	11394	-0.062	-0.2517	No
90	Gypc	11424	-0.064	-0.2515	No
91	Marchf8	11455	-0.065	-0.2514	No
92	Atp6v0a1	11504	-0.066	-0.2522	No
93	Add1	11622	-0.071	-0.2565	No
94	Gde1	11732	-0.075	-0.2603	No
95	Pdzk1ip1	11762	-0.076	-0.2598	No
96	Cir1	11780	-0.076	-0.2587	No
97	Mboat2	11819	-0.078	-0.2587	No
98	Vezf1	11820	-0.078	-0.2567	No
99	Top1	11884	-0.081	-0.2579	No
100	Foxo3	11891	-0.081	-0.2561	No
101	Rbm38	11920	-0.082	-0.2554	No
102	Lrp10	11931	-0.082	-0.2538	No
103	Clcn3	12137	-0.089	-0.2622	No
104	Fbxo9	12156	-0.089	-0.2608	No
105	Ucp2	12167	-0.090	-0.2590	No
106	Ackr1	12336	-0.097	-0.2653	No
107	Abcb6	12441	-0.101	-0.2681	No
108	Mgst3	12487	-0.103	-0.2678	No
109	Htatip2	12492	-0.103	-0.2654	No
110	Blvra	12598	-0.107	-0.2681	No
111	Hdgf	12666	-0.109	-0.2687	No
112	C3	12678	-0.110	-0.2665	No
113	Fech	12741	-0.112	-0.2668	No
114	Smox	13107	-0.125	-0.2826	No
115	Igsf3	13274	-0.132	-0.2879	No
116	Cat	13396	-0.137	-0.2907	No
117	Atg4a	13536	-0.143	-0.2942	No
118	Khnyn	13927	-0.159	-0.3105	No
119	Gclm	13930	-0.159	-0.3065	No
120	Lamp2	14054	-0.166	-0.3086	No
121	Sdcbp	14104	-0.168	-0.3068	No
122	Tns1	14110	-0.168	-0.3027	No
123	Ctse	14238	-0.173	-0.3049	No
124	Ranbp10	14301	-0.176	-0.3035	No
125	Narf	14549	-0.188	-0.3116	No
126	Eif2ak1	14615	-0.191	-0.3100	No
127	Mpp1	14691	-0.195	-0.3089	No
128	Tnrc6b	14824	-0.202	-0.3106	No
129	Fn3k	14866	-0.204	-0.3074	No
130	Adipor1	15014	-0.207	-0.3097	No
131	Snca	15084	-0.211	-0.3079	No
132	Slc30a1	15302	-0.222	-0.3134	No
133	Alad	15487	-0.231	-0.3171	No
134	Arl2bp	15608	-0.237	-0.3172	No
135	Epor	15680	-0.240	-0.3147	No
136	Rhd	15942	-0.254	-0.3217	Yes
137	Ypel5	16028	-0.257	-0.3195	Yes
138	Optn	16041	-0.258	-0.3134	Yes
139	Arhgef12	16052	-0.259	-0.3072	Yes
140	Slc6a8	16356	-0.277	-0.3159	Yes
141	Icam4	16437	-0.282	-0.3128	Yes
142	Kat2b	16486	-0.284	-0.3079	Yes
143	Pgls	16619	-0.291	-0.3073	Yes
144	Slc22a4	16689	-0.296	-0.3032	Yes
145	Sptb	16731	-0.299	-0.2976	Yes
146	Epb41	16770	-0.301	-0.2918	Yes
147	Myl4	16957	-0.314	-0.2934	Yes
148	Tal1	17277	-0.335	-0.3014	Yes
149	Daam1	17292	-0.336	-0.2934	Yes
150	Nfe2	17296	-0.337	-0.2848	Yes
151	Rad23a	17345	-0.340	-0.2785	Yes
152	Mkrn1	17497	-0.355	-0.2772	Yes
153	Acp5	17581	-0.361	-0.2722	Yes
154	Gata1	17672	-0.368	-0.2673	Yes
155	Bsg	17678	-0.368	-0.2580	Yes
156	Marchf2	17692	-0.370	-0.2491	Yes
157	Tspan5	17742	-0.376	-0.2419	Yes
158	Tyr	17814	-0.383	-0.2357	Yes
159	Alas2	17827	-0.384	-0.2264	Yes
160	Xk	17926	-0.395	-0.2213	Yes
161	Kel	17933	-0.396	-0.2113	Yes
162	Riok3	17966	-0.397	-0.2027	Yes
163	Ctns	17988	-0.401	-0.1934	Yes
164	Rap1gap	18065	-0.408	-0.1868	Yes
165	Ppp2r5b	18104	-0.412	-0.1781	Yes
166	Tfdp2	18307	-0.435	-0.1774	Yes
167	Mxi1	18386	-0.447	-0.1699	Yes
168	Mfhas1	18434	-0.455	-0.1605	Yes
169	Htra2	18475	-0.461	-0.1506	Yes
170	Bach1	18514	-0.465	-0.1406	Yes
171	Tmcc2	18530	-0.468	-0.1292	Yes
172	Klf3	18596	-0.479	-0.1202	Yes
173	Slc7a11	18681	-0.496	-0.1117	Yes
174	Trim10	18790	-0.524	-0.1038	Yes
175	Ccdc28a	18833	-0.536	-0.0921	Yes
176	Prdx2	18887	-0.550	-0.0806	Yes
177	Epb42	18937	-0.570	-0.0683	Yes
178	Selenbp1	18976	-0.590	-0.0550	Yes
179	Slc66a2	19096	-0.645	-0.0445	Yes
180	Ccnd3	19192	-0.729	-0.0306	Yes
181	Uros	19306	-1.408	0.0001	Yes