Details for gene set HALLMARK_P53

Table: GSEA Results Summary

Dataset	MEP.MEP.mega_Pheno.cls #Group2_versus_Group4.MEP.mega_Pheno.cls #Group2_versus_Group4_repos
Phenotype	MEP.mega_Pheno.cls#Group2_versus_Group4_repos
Upregulated in class	3
GeneSet	HALLMARK_P53_PATHWAY
Enrichment Score (ES)	-0.31351253
Normalized Enrichment Score (NES)	-1.1935525
Nominal p-value	0.2312253
FDR q-value	0.58684766
FWER p-Value	0.883

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Atf3	374	0.633	-0.0060	No
2	Nupr1	593	0.569	-0.0052	No
3	Gls2	708	0.543	0.0005	No
4	Ninj1	726	0.538	0.0111	No
5	Elp1	740	0.536	0.0219	No
6	Plk2	782	0.528	0.0311	No
7	Cdkn2aip	915	0.509	0.0351	No
8	Ip6k2	1041	0.487	0.0390	No
9	Tgfa	1133	0.475	0.0444	No
10	Polh	1168	0.470	0.0527	No
11	Cdk5r1	1368	0.445	0.0519	No
12	Jun	1406	0.441	0.0594	No
13	App	1804	0.399	0.0472	No
14	Tax1bp3	2374	0.347	0.0248	No
15	Fos	2390	0.346	0.0315	No
16	Ccp110	2543	0.337	0.0307	No
17	Xpc	2793	0.318	0.0245	No
18	Ier5	3100	0.298	0.0149	No
19	F2r	3185	0.292	0.0168	No
20	Pcna	3297	0.284	0.0170	No
21	Ercc5	3349	0.281	0.0204	No
22	Sp1	3388	0.278	0.0244	No
23	Blcap	3462	0.273	0.0264	No
24	Fgf13	3609	0.264	0.0244	No
25	Pmm1	3973	0.243	0.0106	No
26	Vwa5a	4121	0.236	0.0080	No
27	Trib3	4204	0.231	0.0087	No
28	Apaf1	4230	0.230	0.0123	No
29	Slc35d1	4259	0.228	0.0157	No
30	Csrnp2	4380	0.220	0.0142	No
31	Rxra	4412	0.219	0.0172	No
32	Pvt1	4716	0.202	0.0057	No
33	Tm7sf3	4730	0.201	0.0093	No
34	Trp63	4880	0.193	0.0057	No
35	Hbegf	4974	0.188	0.0048	No
36	Sfn	4990	0.187	0.0081	No
37	Btg2	5069	0.184	0.0079	No
38	Acvr1b	5302	0.175	-0.0005	No
39	Fbxw7	5690	0.158	-0.0173	No
40	Upp1	5718	0.157	-0.0154	No
41	Foxo3	5994	0.143	-0.0267	No
42	Dgka	6216	0.132	-0.0354	No
43	Baiap2	6359	0.125	-0.0402	No
44	Ctsd	6702	0.108	-0.0557	No
45	Bmp2	6704	0.108	-0.0535	No
46	Ralgds	7043	0.092	-0.0692	No
47	Triap1	7106	0.089	-0.0705	No
48	Dram1	7392	0.077	-0.0838	No
49	H1f2	7624	0.067	-0.0944	No
50	Prmt2	7689	0.065	-0.0963	No
51	Hspa4l	7761	0.061	-0.0988	No
52	Retsat	7839	0.059	-0.1015	No
53	Abcc5	7948	0.054	-0.1060	No
54	Rchy1	8263	0.041	-0.1216	No
55	Fuca1	8422	0.033	-0.1291	No
56	Ddit4	8590	0.025	-0.1373	No
57	Ddit3	8600	0.024	-0.1373	No
58	Irag2	8638	0.023	-0.1387	No
59	Notch1	8681	0.020	-0.1405	No
60	Mdm2	8752	0.018	-0.1438	No
61	Ccng1	8775	0.017	-0.1446	No
62	Osgin1	8892	0.013	-0.1503	No
63	Aen	8931	0.012	-0.1521	No
64	Fdxr	9416	-0.005	-0.1773	No
65	Wwp1	9446	-0.007	-0.1786	No
66	Rap2b	9471	-0.008	-0.1797	No
67	Sesn1	9481	-0.008	-0.1800	No
68	Ak1	9551	-0.011	-0.1834	No
69	Kif13b	9733	-0.019	-0.1925	No
70	Cdkn1a	9757	-0.020	-0.1932	No
71	Plxnb2	9788	-0.021	-0.1944	No
72	Klf4	9839	-0.023	-0.1965	No
73	Cdkn2a	9948	-0.028	-0.2015	No
74	Hmox1	10117	-0.034	-0.2096	No
75	Hdac3	10118	-0.034	-0.2088	No
76	Bax	10479	-0.050	-0.2266	No
77	Itgb4	10481	-0.050	-0.2256	No
78	S100a4	10569	-0.053	-0.2290	No
79	Cd81	10596	-0.054	-0.2292	No
80	Coq8a	10611	-0.055	-0.2287	No
81	Slc3a2	10630	-0.056	-0.2285	No
82	Ptpn14	10992	-0.069	-0.2459	No
83	Cdh13	11050	-0.072	-0.2473	No
84	Rnf19b	11071	-0.073	-0.2468	No
85	Rad51c	11144	-0.076	-0.2489	No
86	Rb1	11196	-0.078	-0.2499	No
87	Casp1	11221	-0.079	-0.2495	No
88	Sdc1	11237	-0.079	-0.2486	No
89	Stom	11297	-0.082	-0.2499	No
90	Rrad	11338	-0.084	-0.2502	No
91	Abat	11406	-0.087	-0.2519	No
92	Tspyl2	11413	-0.087	-0.2503	No
93	Ephx1	11476	-0.089	-0.2516	No
94	Sat1	11774	-0.100	-0.2650	No
95	Btg1	11874	-0.105	-0.2679	No
96	Il1a	12028	-0.111	-0.2736	No
97	Nudt15	12240	-0.120	-0.2820	No
98	Plk3	12504	-0.132	-0.2929	No
99	H2ac25	12540	-0.134	-0.2919	No
100	Socs1	12569	-0.135	-0.2905	No
101	Hexim1	12601	-0.136	-0.2892	No
102	Mapkapk3	12644	-0.139	-0.2884	No
103	Cebpa	12838	-0.148	-0.2953	No
104	Jag2	12915	-0.151	-0.2961	No
105	Ankra2	12957	-0.153	-0.2949	No
106	Txnip	12963	-0.154	-0.2919	No
107	Tob1	13018	-0.156	-0.2914	No
108	Tcn2	13080	-0.158	-0.2912	No
109	Zmat3	13092	-0.158	-0.2884	No
110	Ccnd3	13125	-0.160	-0.2866	No
111	Trafd1	13318	-0.169	-0.2930	No
112	Mxd1	13354	-0.170	-0.2912	No
113	Rhbdf2	13501	-0.177	-0.2951	No
114	Trp53	13548	-0.179	-0.2936	No
115	Pidd1	13662	-0.185	-0.2956	No
116	Eps8l2	13821	-0.193	-0.2997	No
117	Rab40c	13878	-0.195	-0.2985	No
118	St14	14026	-0.202	-0.3018	No
119	Zfp365	14228	-0.211	-0.3078	No
120	Phlda3	14276	-0.213	-0.3057	No
121	Wrap73	14302	-0.214	-0.3024	No
122	Mknk2	14308	-0.214	-0.2981	No
123	Mxd4	14309	-0.214	-0.2935	No
124	Cgrrf1	14644	-0.231	-0.3060	No
125	Tsc22d1	14788	-0.238	-0.3084	Yes
126	Nol8	14797	-0.239	-0.3037	Yes
127	Ndrg1	14826	-0.241	-0.3000	Yes
128	Zfp36l1	14880	-0.243	-0.2976	Yes
129	Pdgfa	14891	-0.244	-0.2929	Yes
130	Slc7a11	14894	-0.244	-0.2877	Yes
131	Ctsf	14965	-0.249	-0.2860	Yes
132	Ccnk	14985	-0.250	-0.2817	Yes
133	Rrp8	15254	-0.263	-0.2901	Yes
134	Procr	15291	-0.266	-0.2862	Yes
135	Rad9a	15320	-0.268	-0.2820	Yes
136	Vamp8	15540	-0.280	-0.2874	Yes
137	Tnfsf9	15562	-0.281	-0.2825	Yes
138	Zbtb16	15613	-0.285	-0.2790	Yes
139	Sphk1	15707	-0.289	-0.2777	Yes
140	Ldhb	15748	-0.291	-0.2735	Yes
141	Pitpnc1	15911	-0.301	-0.2755	Yes
142	Traf4	16038	-0.309	-0.2755	Yes
143	Ppm1d	16169	-0.318	-0.2755	Yes
144	Tgfb1	16242	-0.323	-0.2723	Yes
145	Epha2	16249	-0.324	-0.2657	Yes
146	Rpl18	16297	-0.327	-0.2612	Yes
147	Slc19a2	16336	-0.329	-0.2561	Yes
148	Hint1	16384	-0.331	-0.2514	Yes
149	Rpl36	16456	-0.337	-0.2479	Yes
150	Ier3	16477	-0.339	-0.2417	Yes
151	Ei24	16491	-0.341	-0.2351	Yes
152	Steap3	16653	-0.351	-0.2360	Yes
153	Ppp1r15a	16684	-0.353	-0.2300	Yes
154	Cyfip2	16918	-0.371	-0.2342	Yes
155	Gm2a	17008	-0.378	-0.2308	Yes
156	Ccnd2	17053	-0.382	-0.2249	Yes
157	Perp	17116	-0.387	-0.2199	Yes
158	Sertad3	17228	-0.396	-0.2172	Yes
159	Ddb2	17358	-0.405	-0.2152	Yes
160	Tap1	17367	-0.406	-0.2070	Yes
161	Ifi30	17409	-0.410	-0.2003	Yes
162	Tpd52l1	17418	-0.411	-0.1919	Yes
163	Ptpre	17447	-0.414	-0.1845	Yes
164	Rps27l	17527	-0.420	-0.1796	Yes
165	Def6	17579	-0.426	-0.1732	Yes
166	Fas	17610	-0.428	-0.1656	Yes
167	Bak1	17740	-0.443	-0.1628	Yes
168	S100a10	17741	-0.443	-0.1533	Yes
169	H2aj	17765	-0.446	-0.1450	Yes
170	Sec61a1	17789	-0.449	-0.1365	Yes
171	Abhd4	17833	-0.453	-0.1291	Yes
172	Dnttip2	17850	-0.455	-0.1202	Yes
173	Pom121	17937	-0.464	-0.1147	Yes
174	Dcxr	18092	-0.486	-0.1123	Yes
175	Fam162a	18096	-0.487	-0.1021	Yes
176	Rps12	18111	-0.489	-0.0923	Yes
177	Cd82	18122	-0.491	-0.0823	Yes
178	Tprkb	18213	-0.504	-0.0762	Yes
179	Ada	18382	-0.530	-0.0737	Yes
180	Gadd45a	18603	-0.572	-0.0729	Yes
181	Rack1	18719	-0.600	-0.0660	Yes
182	Klk8	18732	-0.604	-0.0537	Yes
183	Irak1	18734	-0.604	-0.0408	Yes
184	Vdr	18996	-0.701	-0.0395	Yes
185	Iscu	19059	-0.738	-0.0269	Yes
186	Prkab1	19182	-0.844	-0.0152	Yes
187	Hras	19258	-1.011	0.0026	Yes