Details for gene set HALLMARK_IL6_JAK_STAT3

Table: GSEA Results Summary

Dataset	MEP.MEP.mega_Pheno.cls #Group2_versus_Group4.MEP.mega_Pheno.cls #Group2_versus_Group4_repos
Phenotype	MEP.mega_Pheno.cls#Group2_versus_Group4_repos
Upregulated in class	3
GeneSet	HALLMARK_IL6_JAK_STAT3_SIGNALING
Enrichment Score (ES)	-0.27547616
Normalized Enrichment Score (NES)	-1.0247061
Nominal p-value	0.39361703
FDR q-value	0.8207357
FWER p-Value	0.976

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Pdgfc	754	0.533	-0.0095	No
2	Il6st	917	0.509	0.0104	No
3	Il1b	942	0.505	0.0372	No
4	Il17rb	1276	0.457	0.0453	No
5	Jun	1406	0.441	0.0632	No
6	Il4ra	1451	0.435	0.0850	No
7	Stam2	1733	0.407	0.0931	No
8	Pim1	1836	0.396	0.1098	No
9	Il1r1	2064	0.374	0.1189	No
10	Stat3	2090	0.371	0.1382	No
11	Myd88	2269	0.354	0.1486	No
12	Il18r1	2291	0.351	0.1671	No
13	Tnfrsf12a	2844	0.312	0.1558	No
14	Il6	3265	0.286	0.1499	No
15	Csf3r	4381	0.220	0.1042	No
16	Acvr1b	5302	0.175	0.0661	No
17	Pik3r5	5352	0.173	0.0732	No
18	Il1r2	5523	0.164	0.0734	No
19	Ptpn11	6076	0.138	0.0524	No
20	Socs3	6230	0.131	0.0518	No
21	Csf1	6439	0.121	0.0477	No
22	Hax1	6512	0.117	0.0505	No
23	Itgb3	6838	0.102	0.0392	No
24	Irf9	7121	0.089	0.0295	No
25	Irf1	7585	0.069	0.0093	No
26	Ptpn1	8109	0.048	-0.0153	No
27	Grb2	8411	0.033	-0.0291	No
28	Ptpn2	8524	0.028	-0.0333	No
29	Ifnar1	8746	0.018	-0.0438	No
30	Il15ra	8820	0.015	-0.0468	No
31	Ebi3	8951	0.011	-0.0529	No
32	Ifngr2	9173	0.002	-0.0643	No
33	Il13ra1	9217	0.000	-0.0665	No
34	Tnfrsf1b	9526	-0.010	-0.0820	No
35	Cbl	9540	-0.011	-0.0821	No
36	Stat2	9801	-0.021	-0.0944	No
37	Hmox1	10117	-0.034	-0.1088	No
38	Stat1	10690	-0.058	-0.1353	No
39	Dntt	12424	-0.128	-0.2183	No
40	Cd44	12511	-0.133	-0.2154	No
41	Itga4	12515	-0.133	-0.2082	No
42	Socs1	12569	-0.135	-0.2034	No
43	Tyk2	12614	-0.137	-0.1981	No
44	Il17ra	13095	-0.158	-0.2142	No
45	Il2rg	13236	-0.165	-0.2123	No
46	Ifngr1	13346	-0.170	-0.2085	No
47	Il3ra	13690	-0.187	-0.2160	No
48	Cd9	13823	-0.193	-0.2121	No
49	Tlr2	13927	-0.198	-0.2065	No
50	Il7	14369	-0.217	-0.2173	No
51	Crlf2	14566	-0.227	-0.2149	No
52	Cxcl10	15733	-0.290	-0.2593	Yes
53	Map3k8	15829	-0.296	-0.2478	Yes
54	Tnf	16117	-0.315	-0.2452	Yes
55	Cd38	16145	-0.316	-0.2290	Yes
56	Tgfb1	16242	-0.323	-0.2160	Yes
57	Ccr1	16562	-0.345	-0.2133	Yes
58	Ltb	16838	-0.365	-0.2073	Yes
59	Pf4	16913	-0.371	-0.1905	Yes
60	Il12rb1	16985	-0.376	-0.1733	Yes
61	Fas	17610	-0.428	-0.1819	Yes
62	Tnfrsf1a	17655	-0.433	-0.1601	Yes
63	Bak1	17740	-0.443	-0.1398	Yes
64	Cd36	17852	-0.455	-0.1202	Yes
65	Il10rb	18095	-0.487	-0.1057	Yes
66	Tnfrsf21	18519	-0.553	-0.0970	Yes
67	Lepr	18841	-0.634	-0.0784	Yes
68	Ltbr	19026	-0.716	-0.0481	Yes
69	Csf2ra	19280	-1.125	0.0014	Yes