Details for gene set HALLMARK_E2F

Table: GSEA Results Summary

Dataset	MEP.MEP.mega_Pheno.cls #Group2_versus_Group3.MEP.mega_Pheno.cls #Group2_versus_Group3_repos
Phenotype	MEP.mega_Pheno.cls#Group2_versus_Group3_repos
Upregulated in class	2
GeneSet	HALLMARK_E2F_TARGETS
Enrichment Score (ES)	-0.27992725
Normalized Enrichment Score (NES)	-0.94996715
Nominal p-value	0.4958159
FDR q-value	0.84657884
FWER p-Value	0.996

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Donson	901	0.454	-0.0356	No
2	Srsf1	932	0.451	-0.0258	No
3	Dck	1059	0.430	-0.0215	No
4	Zw10	1198	0.413	-0.0182	No
5	Tfrc	1649	0.369	-0.0324	No
6	Ipo7	1803	0.356	-0.0314	No
7	Bub1b	1879	0.350	-0.0264	No
8	Lmnb1	2006	0.342	-0.0244	No
9	Dlgap5	2088	0.334	-0.0201	No
10	Lsm8	2272	0.321	-0.0216	No
11	Aurka	2385	0.312	-0.0195	No
12	Hnrnpd	2710	0.289	-0.0291	No
13	Smc3	2782	0.284	-0.0256	No
14	Dnmt1	2904	0.276	-0.0250	No
15	Pcna	2984	0.271	-0.0223	No
16	Cdkn1b	3003	0.270	-0.0164	No
17	Ilf3	3005	0.270	-0.0096	No
18	Mlh1	3586	0.235	-0.0340	No
19	Chek2	3694	0.229	-0.0337	No
20	Prps1	3929	0.216	-0.0405	No
21	Plk1	3981	0.214	-0.0378	No
22	Ncapd2	4040	0.212	-0.0354	No
23	Ccp110	4053	0.211	-0.0307	No
24	Rad21	4167	0.206	-0.0314	No
25	Xpo1	4355	0.197	-0.0362	No
26	Hus1	4408	0.194	-0.0340	No
27	Psmc3ip	4458	0.191	-0.0317	No
28	Cdkn2c	4507	0.188	-0.0294	No
29	Cdc25a	4632	0.182	-0.0313	No
30	Depdc1a	4757	0.177	-0.0333	No
31	Brms1l	4820	0.175	-0.0321	No
32	Pnn	4842	0.174	-0.0288	No
33	Mre11a	5011	0.166	-0.0334	No
34	Nasp	5147	0.161	-0.0364	No
35	Lbr	5161	0.160	-0.0330	No
36	Atad2	5172	0.160	-0.0295	No
37	Brca1	5208	0.158	-0.0273	No
38	Xrcc6	5227	0.157	-0.0242	No
39	Anp32e	5354	0.152	-0.0270	No
40	Racgap1	5378	0.151	-0.0244	No
41	Msh2	5392	0.151	-0.0212	No
42	Phf5a	5537	0.145	-0.0251	No
43	Rpa1	5727	0.137	-0.0315	No
44	Syncrip	5830	0.132	-0.0335	No
45	Melk	5996	0.125	-0.0390	No
46	Gins3	6335	0.110	-0.0539	No
47	Eif2s1	6492	0.103	-0.0594	No
48	Smc1a	6652	0.098	-0.0652	No
49	Prkdc	6810	0.091	-0.0711	No
50	Nolc1	6853	0.089	-0.0711	No
51	Lyar	6923	0.087	-0.0725	No
52	Slbp	6975	0.085	-0.0730	No
53	Nudt21	6995	0.084	-0.0719	No
54	Shmt1	7028	0.083	-0.0714	No
55	Kif2c	7043	0.082	-0.0701	No
56	Nap1l1	7071	0.081	-0.0695	No
57	Nup107	7120	0.079	-0.0700	No
58	Top2a	7161	0.077	-0.0701	No
59	Cdk1	7168	0.077	-0.0685	No
60	Mcm6	7328	0.071	-0.0750	No
61	Mcm2	7373	0.069	-0.0755	No
62	Prim2	7410	0.068	-0.0757	No
63	Wdr90	7641	0.059	-0.0862	No
64	Aurkb	7649	0.059	-0.0851	No
65	Luc7l3	7745	0.055	-0.0887	No
66	Stag1	7763	0.055	-0.0882	No
67	Birc5	7813	0.053	-0.0894	No
68	Lig1	7840	0.053	-0.0894	No
69	Plk4	7901	0.050	-0.0913	No
70	Kif22	7903	0.050	-0.0901	No
71	Ubr7	7954	0.048	-0.0915	No
72	Nup153	7976	0.047	-0.0914	No
73	Cse1l	8166	0.039	-0.1003	No
74	Ssrp1	8264	0.036	-0.1045	No
75	Ak2	8355	0.032	-0.1083	No
76	Hmmr	8426	0.029	-0.1113	No
77	Diaph3	8477	0.028	-0.1132	No
78	Tmpo	8669	0.021	-0.1226	No
79	Ran	8713	0.019	-0.1244	No
80	Nup205	8830	0.015	-0.1301	No
81	Hmgb3	8860	0.014	-0.1313	No
82	Kif4	8968	0.010	-0.1366	No
83	Mms22l	8979	0.010	-0.1369	No
84	Pds5b	9154	0.003	-0.1459	No
85	Hmga1b	9225	0.000	-0.1496	No
86	Pold3	9473	-0.006	-0.1623	No
87	Jpt1	9535	-0.009	-0.1653	No
88	Cenpe	9546	-0.009	-0.1656	No
89	Cit	9577	-0.010	-0.1669	No
90	Ezh2	9825	-0.018	-0.1793	No
91	Nbn	9976	-0.025	-0.1866	No
92	Brca2	10099	-0.029	-0.1922	No
93	Pan2	10124	-0.030	-0.1927	No
94	Ube2t	10164	-0.031	-0.1940	No
95	Orc2	10377	-0.040	-0.2040	No
96	Paics	10400	-0.041	-0.2041	No
97	Tra2b	10779	-0.055	-0.2225	No
98	Dut	10836	-0.058	-0.2240	No
99	Cdca8	10895	-0.060	-0.2255	No
100	Wee1	10903	-0.060	-0.2244	No
101	Ddx39a	10935	-0.061	-0.2244	No
102	Trp53	10976	-0.063	-0.2249	No
103	Espl1	10992	-0.064	-0.2241	No
104	Eed	11020	-0.065	-0.2239	No
105	Snrpb	11024	-0.065	-0.2224	No
106	Spc25	11068	-0.067	-0.2230	No
107	H2az1	11082	-0.067	-0.2219	No
108	Rbbp7	11227	-0.073	-0.2276	No
109	Mcm3	11266	-0.074	-0.2277	No
110	Cks2	11528	-0.084	-0.2393	No
111	Pa2g4	11553	-0.085	-0.2384	No
112	Psip1	11597	-0.086	-0.2384	No
113	Tacc3	11659	-0.089	-0.2394	No
114	Cbx5	11692	-0.091	-0.2388	No
115	Mybl2	11694	-0.091	-0.2365	No
116	Suv39h1	11745	-0.093	-0.2368	No
117	Tbrg4	11858	-0.098	-0.2401	No
118	Orc6	11877	-0.099	-0.2386	No
119	Smc4	11885	-0.099	-0.2364	No
120	Rad50	11893	-0.100	-0.2343	No
121	Exosc8	11994	-0.104	-0.2368	No
122	Ppp1r8	12040	-0.106	-0.2365	No
123	Hmgb2	12059	-0.107	-0.2348	No
124	Spag5	12297	-0.115	-0.2442	No
125	Ppm1d	12336	-0.118	-0.2432	No
126	Gspt1	12405	-0.120	-0.2437	No
127	Smc6	12413	-0.121	-0.2410	No
128	Bard1	12614	-0.130	-0.2482	No
129	E2f8	12683	-0.133	-0.2484	No
130	Mcm7	12812	-0.138	-0.2516	No
131	Chek1	12854	-0.140	-0.2502	No
132	Pole	12924	-0.144	-0.2502	No
133	Mcm5	13069	-0.150	-0.2539	No
134	Rad51c	13113	-0.152	-0.2523	No
135	Tk1	13377	-0.163	-0.2619	No
136	Mcm4	13418	-0.164	-0.2598	No
137	Mki67	13557	-0.170	-0.2627	No
138	Usp1	13603	-0.173	-0.2607	No
139	Ccne1	13815	-0.181	-0.2671	No
140	Mad2l1	13854	-0.184	-0.2644	No
141	Mthfd2	14128	-0.197	-0.2737	No
142	Ube2s	14135	-0.197	-0.2690	No
143	Pola2	14309	-0.206	-0.2729	No
144	Rfc1	14445	-0.214	-0.2745	Yes
145	Myc	14460	-0.214	-0.2698	Yes
146	Cdc25b	14464	-0.214	-0.2645	Yes
147	Rrm2	14486	-0.216	-0.2602	Yes
148	Pold1	14587	-0.220	-0.2598	Yes
149	Trip13	14616	-0.221	-0.2557	Yes
150	Cdkn1a	14702	-0.226	-0.2544	Yes
151	Pms2	14768	-0.230	-0.2520	Yes
152	Ctcf	14792	-0.231	-0.2473	Yes
153	Nop56	14805	-0.231	-0.2421	Yes
154	Rnaseh2a	14806	-0.231	-0.2362	Yes
155	Nme1	14860	-0.234	-0.2331	Yes
156	Asf1a	14952	-0.239	-0.2317	Yes
157	Dek	15195	-0.253	-0.2380	Yes
158	Dclre1b	15355	-0.262	-0.2397	Yes
159	Cdk4	15379	-0.263	-0.2342	Yes
160	Ranbp1	15597	-0.274	-0.2386	Yes
161	Cnot9	15694	-0.279	-0.2366	Yes
162	Tubb5	15748	-0.283	-0.2322	Yes
163	Pold2	16087	-0.308	-0.2420	Yes
164	Cenpm	16274	-0.320	-0.2437	Yes
165	Tcf19	16299	-0.322	-0.2368	Yes
166	Asf1b	16321	-0.323	-0.2297	Yes
167	Ccnb2	16414	-0.329	-0.2261	Yes
168	Tipin	16563	-0.338	-0.2253	Yes
169	Rad51ap1	16719	-0.349	-0.2246	Yes
170	Gins4	16771	-0.353	-0.2183	Yes
171	Kif18b	16893	-0.363	-0.2154	Yes
172	Timeless	16940	-0.367	-0.2086	Yes
173	H2ax	16969	-0.368	-0.2007	Yes
174	Srsf2	17013	-0.374	-0.1935	Yes
175	Stmn1	17015	-0.374	-0.1840	Yes
176	Spc24	17074	-0.378	-0.1775	Yes
177	Hells	17134	-0.384	-0.1708	Yes
178	Prdx4	17273	-0.396	-0.1680	Yes
179	Cks1b	17434	-0.408	-0.1660	Yes
180	Cdc20	17529	-0.416	-0.1604	Yes
181	Dctpp1	17666	-0.428	-0.1567	Yes
182	Tubg1	17964	-0.460	-0.1605	Yes
183	Cdkn3	18049	-0.473	-0.1529	Yes
184	Rfc2	18111	-0.483	-0.1439	Yes
185	Rad1	18245	-0.503	-0.1381	Yes
186	Rfc3	18250	-0.504	-0.1255	Yes
187	Rpa3	18260	-0.505	-0.1132	Yes
188	Pttg1	18311	-0.516	-0.1027	Yes
189	Gins1	18398	-0.533	-0.0937	Yes
190	Rpa2	18406	-0.535	-0.0805	Yes
191	Ung	18442	-0.542	-0.0686	Yes
192	Dscc1	18482	-0.549	-0.0567	Yes
193	Ing3	18487	-0.549	-0.0430	Yes
194	Pop7	18563	-0.569	-0.0325	Yes
195	Mxd3	18734	-0.605	-0.0261	Yes
196	Cdkn2a	18755	-0.611	-0.0116	Yes
197	Pole4	19066	-0.748	-0.0089	Yes
198	Cdca3	19183	-0.845	0.0065	Yes