| Dataset | MEP.MEP.mega_Pheno.cls #Group2_versus_Group3.MEP.mega_Pheno.cls #Group2_versus_Group3_repos |
| Phenotype | MEP.mega_Pheno.cls#Group2_versus_Group3_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_COMPLEMENT |
| Enrichment Score (ES) | 0.19732335 |
| Normalized Enrichment Score (NES) | 0.8606266 |
| Nominal p-value | 0.75848305 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Olr1 | 180 | 0.675 | 0.0082 | Yes |
| 2 | C1qc | 319 | 0.596 | 0.0165 | Yes |
| 3 | Casp4 | 423 | 0.559 | 0.0257 | Yes |
| 4 | Ctsh | 510 | 0.532 | 0.0351 | Yes |
| 5 | Cr2 | 734 | 0.486 | 0.0361 | Yes |
| 6 | Plaur | 827 | 0.469 | 0.0436 | Yes |
| 7 | Col4a2 | 830 | 0.468 | 0.0557 | Yes |
| 8 | Clu | 875 | 0.459 | 0.0653 | Yes |
| 9 | Lcp2 | 988 | 0.441 | 0.0710 | Yes |
| 10 | Notch4 | 1103 | 0.422 | 0.0760 | Yes |
| 11 | Spock2 | 1153 | 0.418 | 0.0844 | Yes |
| 12 | Plek | 1178 | 0.415 | 0.0939 | Yes |
| 13 | Tnfaip3 | 1239 | 0.409 | 0.1015 | Yes |
| 14 | Cdk5r1 | 1447 | 0.389 | 0.1008 | Yes |
| 15 | Prkcd | 1644 | 0.370 | 0.1003 | Yes |
| 16 | Anxa5 | 1660 | 0.368 | 0.1091 | Yes |
| 17 | Kynu | 1725 | 0.362 | 0.1152 | Yes |
| 18 | Pclo | 1738 | 0.361 | 0.1240 | Yes |
| 19 | Pla2g7 | 1740 | 0.361 | 0.1333 | Yes |
| 20 | Rasgrp1 | 1818 | 0.355 | 0.1385 | Yes |
| 21 | Ctsc | 1955 | 0.345 | 0.1404 | Yes |
| 22 | Il6 | 2038 | 0.339 | 0.1450 | Yes |
| 23 | Adam9 | 2070 | 0.336 | 0.1521 | Yes |
| 24 | F5 | 2080 | 0.335 | 0.1604 | Yes |
| 25 | Fn1 | 2100 | 0.332 | 0.1681 | Yes |
| 26 | Hspa1a | 2123 | 0.331 | 0.1755 | Yes |
| 27 | Kif2a | 2159 | 0.330 | 0.1823 | Yes |
| 28 | Gp1ba | 2163 | 0.330 | 0.1908 | Yes |
| 29 | Itgam | 2201 | 0.326 | 0.1973 | Yes |
| 30 | Lamp2 | 2559 | 0.301 | 0.1865 | No |
| 31 | Jak2 | 2590 | 0.299 | 0.1928 | No |
| 32 | Cp | 2732 | 0.288 | 0.1929 | No |
| 33 | Pim1 | 2968 | 0.272 | 0.1877 | No |
| 34 | Lyn | 3367 | 0.247 | 0.1734 | No |
| 35 | Cd46 | 3438 | 0.243 | 0.1761 | No |
| 36 | Zfpm2 | 3562 | 0.236 | 0.1758 | No |
| 37 | Serpinb2 | 3679 | 0.230 | 0.1757 | No |
| 38 | Pcsk9 | 3755 | 0.226 | 0.1777 | No |
| 39 | Src | 4336 | 0.198 | 0.1526 | No |
| 40 | Raf1 | 4446 | 0.192 | 0.1519 | No |
| 41 | Stx4a | 4476 | 0.190 | 0.1553 | No |
| 42 | Dock9 | 4553 | 0.186 | 0.1562 | No |
| 43 | Lta4h | 4590 | 0.184 | 0.1591 | No |
| 44 | Maff | 4592 | 0.184 | 0.1638 | No |
| 45 | Rbsn | 4705 | 0.179 | 0.1627 | No |
| 46 | Sirt6 | 4872 | 0.172 | 0.1585 | No |
| 47 | Vcpip1 | 4893 | 0.172 | 0.1619 | No |
| 48 | F10 | 5015 | 0.166 | 0.1599 | No |
| 49 | Psen1 | 5168 | 0.160 | 0.1562 | No |
| 50 | S100a13 | 5189 | 0.159 | 0.1593 | No |
| 51 | Cpq | 5481 | 0.147 | 0.1479 | No |
| 52 | Gp9 | 5594 | 0.142 | 0.1458 | No |
| 53 | Dgkg | 5641 | 0.140 | 0.1470 | No |
| 54 | Cfb | 6023 | 0.123 | 0.1303 | No |
| 55 | Kcnip2 | 6044 | 0.122 | 0.1325 | No |
| 56 | Sh2b3 | 6061 | 0.121 | 0.1348 | No |
| 57 | Pik3ca | 6221 | 0.114 | 0.1295 | No |
| 58 | Usp8 | 6377 | 0.108 | 0.1242 | No |
| 59 | Prep | 6517 | 0.103 | 0.1196 | No |
| 60 | L3mbtl4 | 6529 | 0.102 | 0.1217 | No |
| 61 | Usp15 | 6650 | 0.098 | 0.1180 | No |
| 62 | Msrb1 | 7242 | 0.074 | 0.0890 | No |
| 63 | Lgmn | 7255 | 0.073 | 0.0903 | No |
| 64 | Lck | 7264 | 0.073 | 0.0918 | No |
| 65 | S100a9 | 7594 | 0.061 | 0.0762 | No |
| 66 | Cblb | 7716 | 0.057 | 0.0714 | No |
| 67 | Lrp1 | 7769 | 0.055 | 0.0701 | No |
| 68 | Xpnpep1 | 7935 | 0.049 | 0.0627 | No |
| 69 | F7 | 7937 | 0.049 | 0.0639 | No |
| 70 | Gnai3 | 7984 | 0.046 | 0.0627 | No |
| 71 | Fyn | 8410 | 0.030 | 0.0413 | No |
| 72 | Prcp | 8570 | 0.025 | 0.0337 | No |
| 73 | Ctss | 8614 | 0.023 | 0.0320 | No |
| 74 | Gmfb | 8680 | 0.020 | 0.0291 | No |
| 75 | Ppp4c | 8816 | 0.015 | 0.0225 | No |
| 76 | Dgkh | 8921 | 0.012 | 0.0174 | No |
| 77 | Cd36 | 9162 | 0.003 | 0.0049 | No |
| 78 | Ltf | 9236 | 0.000 | 0.0011 | No |
| 79 | Gnai2 | 9373 | -0.003 | -0.0059 | No |
| 80 | Pla2g4a | 9555 | -0.010 | -0.0151 | No |
| 81 | Gzmb | 9629 | -0.012 | -0.0186 | No |
| 82 | Lgals3 | 9702 | -0.014 | -0.0220 | No |
| 83 | Cdh13 | 9751 | -0.015 | -0.0241 | No |
| 84 | Plscr1 | 9824 | -0.018 | -0.0274 | No |
| 85 | Irf1 | 10147 | -0.031 | -0.0434 | No |
| 86 | Cda | 10253 | -0.035 | -0.0480 | No |
| 87 | Usp16 | 10270 | -0.035 | -0.0479 | No |
| 88 | Lap3 | 10287 | -0.036 | -0.0478 | No |
| 89 | Was | 10528 | -0.046 | -0.0591 | No |
| 90 | Zeb1 | 10559 | -0.047 | -0.0595 | No |
| 91 | Usp14 | 10584 | -0.048 | -0.0595 | No |
| 92 | Irf7 | 10723 | -0.053 | -0.0653 | No |
| 93 | Dpp4 | 10907 | -0.060 | -0.0733 | No |
| 94 | Ehd1 | 10929 | -0.061 | -0.0728 | No |
| 95 | Fcer1g | 11431 | -0.080 | -0.0969 | No |
| 96 | Casp3 | 11534 | -0.084 | -0.1000 | No |
| 97 | Ctsb | 11552 | -0.085 | -0.0987 | No |
| 98 | Gpd2 | 11592 | -0.086 | -0.0985 | No |
| 99 | Gca | 11655 | -0.089 | -0.0994 | No |
| 100 | Akap10 | 11668 | -0.089 | -0.0977 | No |
| 101 | Kcnip3 | 11698 | -0.091 | -0.0969 | No |
| 102 | Casp1 | 11844 | -0.097 | -0.1019 | No |
| 103 | Hspa5 | 11927 | -0.101 | -0.1035 | No |
| 104 | Serpinc1 | 12132 | -0.110 | -0.1113 | No |
| 105 | Gng2 | 12150 | -0.111 | -0.1093 | No |
| 106 | Klkb1 | 12390 | -0.120 | -0.1187 | No |
| 107 | C2 | 12425 | -0.121 | -0.1173 | No |
| 108 | Psmb9 | 12672 | -0.133 | -0.1267 | No |
| 109 | Mmp14 | 12737 | -0.136 | -0.1265 | No |
| 110 | Ctsd | 12747 | -0.136 | -0.1234 | No |
| 111 | Dock10 | 12822 | -0.139 | -0.1237 | No |
| 112 | Hnf4a | 13098 | -0.152 | -0.1341 | No |
| 113 | Cebpb | 13106 | -0.152 | -0.1305 | No |
| 114 | Ctso | 13155 | -0.154 | -0.1290 | No |
| 115 | Csrp1 | 13343 | -0.161 | -0.1345 | No |
| 116 | Grb2 | 13356 | -0.162 | -0.1309 | No |
| 117 | F2 | 13615 | -0.174 | -0.1399 | No |
| 118 | Tmprss6 | 13740 | -0.179 | -0.1417 | No |
| 119 | Rnf4 | 13846 | -0.184 | -0.1424 | No |
| 120 | Dusp6 | 13981 | -0.190 | -0.1444 | No |
| 121 | Pik3cg | 14011 | -0.191 | -0.1410 | No |
| 122 | Calm3 | 14136 | -0.197 | -0.1423 | No |
| 123 | Lipa | 14240 | -0.203 | -0.1424 | No |
| 124 | Car2 | 14241 | -0.203 | -0.1371 | No |
| 125 | C3 | 14319 | -0.206 | -0.1357 | No |
| 126 | Fcnb | 14608 | -0.221 | -0.1450 | No |
| 127 | Brpf3 | 14777 | -0.230 | -0.1478 | No |
| 128 | Pik3r5 | 14932 | -0.238 | -0.1496 | No |
| 129 | Rabif | 15129 | -0.248 | -0.1534 | No |
| 130 | Fdx1 | 15351 | -0.261 | -0.1581 | No |
| 131 | Casp7 | 15719 | -0.281 | -0.1699 | No |
| 132 | Rhog | 15781 | -0.285 | -0.1657 | No |
| 133 | Irf2 | 15987 | -0.301 | -0.1686 | No |
| 134 | Casp9 | 16059 | -0.306 | -0.1643 | No |
| 135 | Tfpi2 | 16193 | -0.314 | -0.1630 | No |
| 136 | Dyrk2 | 16230 | -0.317 | -0.1567 | No |
| 137 | Dock4 | 16314 | -0.323 | -0.1526 | No |
| 138 | Gnb4 | 16421 | -0.330 | -0.1495 | No |
| 139 | Cpm | 16561 | -0.338 | -0.1480 | No |
| 140 | Mmp15 | 16734 | -0.350 | -0.1478 | No |
| 141 | Prdm4 | 16754 | -0.352 | -0.1396 | No |
| 142 | Gnb2 | 16756 | -0.352 | -0.1305 | No |
| 143 | Me1 | 16951 | -0.367 | -0.1311 | No |
| 144 | Prss36 | 16991 | -0.371 | -0.1235 | No |
| 145 | Dusp5 | 16998 | -0.372 | -0.1141 | No |
| 146 | Ccl5 | 17185 | -0.388 | -0.1137 | No |
| 147 | Atox1 | 17289 | -0.397 | -0.1087 | No |
| 148 | Pfn1 | 17412 | -0.406 | -0.1045 | No |
| 149 | Calm1 | 17464 | -0.411 | -0.0964 | No |
| 150 | Pdp1 | 17495 | -0.412 | -0.0872 | No |
| 151 | Plg | 17660 | -0.428 | -0.0846 | No |
| 152 | Pdgfb | 17675 | -0.430 | -0.0742 | No |
| 153 | Actn2 | 17725 | -0.435 | -0.0654 | No |
| 154 | Gzmk | 17787 | -0.440 | -0.0571 | No |
| 155 | Rce1 | 18016 | -0.469 | -0.0568 | No |
| 156 | Gata3 | 18182 | -0.494 | -0.0525 | No |
| 157 | Ppp2cb | 18257 | -0.504 | -0.0432 | No |
| 158 | F8 | 18287 | -0.511 | -0.0314 | No |
| 159 | Ctsl | 18390 | -0.531 | -0.0229 | No |
| 160 | Gngt2 | 18630 | -0.582 | -0.0202 | No |
| 161 | Timp2 | 19275 | -1.048 | -0.0265 | No |
| 162 | Phex | 19284 | -1.079 | 0.0012 | No |

