Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | MEP.MEP.mega_Pheno.cls #Group1_versus_Group4.MEP.mega_Pheno.cls #Group1_versus_Group4_repos |
| Phenotype | MEP.mega_Pheno.cls#Group1_versus_Group4_repos |
| Upregulated in class | 0 |
| GeneSet | HALLMARK_TGF_BETA_SIGNALING |
| Enrichment Score (ES) | 0.27267608 |
| Normalized Enrichment Score (NES) | 1.0346947 |
| Nominal p-value | 0.3916501 |
| FDR q-value | 0.8463055 |
| FWER p-Value | 0.974 |
| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Bmpr1a | 64 | 0.905 | 0.0754 | Yes |
| 2 | Cdh1 | 357 | 0.651 | 0.1169 | Yes |
| 3 | Slc20a1 | 874 | 0.519 | 0.1353 | Yes |
| 4 | Skil | 1367 | 0.445 | 0.1484 | Yes |
| 5 | Cdk9 | 1539 | 0.427 | 0.1767 | Yes |
| 6 | Wwtr1 | 1643 | 0.414 | 0.2074 | Yes |
| 7 | Smad3 | 1800 | 0.395 | 0.2336 | Yes |
| 8 | Sptbn1 | 2271 | 0.355 | 0.2401 | Yes |
| 9 | Ncor2 | 2832 | 0.313 | 0.2383 | Yes |
| 10 | Ctnnb1 | 3012 | 0.303 | 0.2554 | Yes |
| 11 | Klf10 | 3170 | 0.292 | 0.2727 | Yes |
| 12 | Hipk2 | 4182 | 0.231 | 0.2403 | No |
| 13 | Id2 | 4656 | 0.206 | 0.2337 | No |
| 14 | Ski | 4759 | 0.201 | 0.2459 | No |
| 15 | Ppm1a | 5852 | 0.147 | 0.2020 | No |
| 16 | Rab31 | 6006 | 0.139 | 0.2062 | No |
| 17 | Tgif1 | 6671 | 0.116 | 0.1818 | No |
| 18 | Trim33 | 6689 | 0.115 | 0.1909 | No |
| 19 | Ube2d3 | 7192 | 0.091 | 0.1728 | No |
| 20 | Rhoa | 8140 | 0.048 | 0.1279 | No |
| 21 | Map3k7 | 9008 | 0.013 | 0.0839 | No |
| 22 | Bcar3 | 9039 | 0.011 | 0.0834 | No |
| 23 | Pmepa1 | 9469 | -0.003 | 0.0613 | No |
| 24 | Hdac1 | 9770 | -0.015 | 0.0470 | No |
| 25 | Tjp1 | 10491 | -0.048 | 0.0138 | No |
| 26 | Cdkn1c | 10513 | -0.049 | 0.0170 | No |
| 27 | Acvr1 | 10760 | -0.061 | 0.0095 | No |
| 28 | Smad7 | 10799 | -0.063 | 0.0130 | No |
| 29 | Xiap | 11439 | -0.091 | -0.0123 | No |
| 30 | Bmp2 | 11796 | -0.107 | -0.0214 | No |
| 31 | Tgfbr1 | 11861 | -0.110 | -0.0152 | No |
| 32 | Furin | 11885 | -0.111 | -0.0067 | No |
| 33 | Arid4b | 11972 | -0.114 | -0.0012 | No |
| 34 | Smurf1 | 12914 | -0.155 | -0.0366 | No |
| 35 | Smad1 | 13065 | -0.161 | -0.0304 | No |
| 36 | Ppp1r15a | 13665 | -0.185 | -0.0454 | No |
| 37 | Smurf2 | 14020 | -0.202 | -0.0461 | No |
| 38 | Ifngr2 | 14066 | -0.206 | -0.0306 | No |
| 39 | Ltbp2 | 14452 | -0.223 | -0.0312 | No |
| 40 | Thbs1 | 14765 | -0.240 | -0.0265 | No |
| 41 | Fkbp1a | 15062 | -0.255 | -0.0197 | No |
| 42 | Fnta | 15600 | -0.285 | -0.0227 | No |
| 43 | Apc | 15856 | -0.300 | -0.0099 | No |
| 44 | Eng | 16068 | -0.315 | 0.0066 | No |
| 45 | Tgfb1 | 16301 | -0.329 | 0.0232 | No |
| 46 | Bmpr2 | 16344 | -0.333 | 0.0500 | No |
| 47 | Junb | 16373 | -0.335 | 0.0777 | No |
| 48 | Smad6 | 16862 | -0.371 | 0.0846 | No |
| 49 | Ppp1ca | 18032 | -0.486 | 0.0662 | No |
