Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | MEP.MEP.mega_Pheno.cls #Group1_versus_Group4.MEP.mega_Pheno.cls #Group1_versus_Group4_repos |
| Phenotype | MEP.mega_Pheno.cls#Group1_versus_Group4_repos |
| Upregulated in class | 3 |
| GeneSet | HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY |
| Enrichment Score (ES) | -0.48848724 |
| Normalized Enrichment Score (NES) | -1.5543905 |
| Nominal p-value | 0.028 |
| FDR q-value | 0.30295944 |
| FWER p-Value | 0.273 |
| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Gpx3 | 91 | 0.847 | 0.0548 | No |
| 2 | Egln2 | 3297 | 0.282 | -0.0919 | No |
| 3 | Mpo | 3622 | 0.262 | -0.0903 | No |
| 4 | Gclc | 5320 | 0.175 | -0.1661 | No |
| 5 | Oxsr1 | 5432 | 0.169 | -0.1600 | No |
| 6 | Txnrd1 | 5628 | 0.159 | -0.1589 | No |
| 7 | Ptpa | 6286 | 0.127 | -0.1841 | No |
| 8 | Fes | 6827 | 0.108 | -0.2046 | No |
| 9 | Mbp | 7291 | 0.087 | -0.2225 | No |
| 10 | Gpx4 | 7467 | 0.079 | -0.2261 | No |
| 11 | Ipcef1 | 8234 | 0.043 | -0.2628 | No |
| 12 | Scaf4 | 8326 | 0.040 | -0.2648 | No |
| 13 | Pfkp | 8331 | 0.040 | -0.2622 | No |
| 14 | Sbno2 | 9206 | 0.003 | -0.3073 | No |
| 15 | Gsr | 9520 | -0.004 | -0.3233 | No |
| 16 | Ercc2 | 9613 | -0.008 | -0.3275 | No |
| 17 | Stk25 | 10536 | -0.050 | -0.3718 | No |
| 18 | Mgst1 | 11782 | -0.107 | -0.4290 | No |
| 19 | Glrx2 | 12307 | -0.128 | -0.4472 | No |
| 20 | Ndufs2 | 12944 | -0.156 | -0.4693 | No |
| 21 | Srxn1 | 12967 | -0.157 | -0.4594 | No |
| 22 | Abcc1 | 13029 | -0.159 | -0.4514 | No |
| 23 | Gclm | 13478 | -0.177 | -0.4622 | No |
| 24 | Txn1 | 13546 | -0.181 | -0.4530 | No |
| 25 | Prdx6 | 13601 | -0.183 | -0.4429 | No |
| 26 | Msra | 13734 | -0.189 | -0.4365 | No |
| 27 | Prnp | 14736 | -0.238 | -0.4718 | Yes |
| 28 | Nqo1 | 14954 | -0.248 | -0.4656 | Yes |
| 29 | G6pdx | 15232 | -0.265 | -0.4614 | Yes |
| 30 | Pdlim1 | 15449 | -0.276 | -0.4533 | Yes |
| 31 | Sod2 | 15468 | -0.277 | -0.4348 | Yes |
| 32 | Prdx1 | 15714 | -0.291 | -0.4271 | Yes |
| 33 | Selenos | 16078 | -0.316 | -0.4237 | Yes |
| 34 | Txnrd2 | 16152 | -0.320 | -0.4051 | Yes |
| 35 | Glrx | 16247 | -0.326 | -0.3870 | Yes |
| 36 | Junb | 16373 | -0.335 | -0.3700 | Yes |
| 37 | Prdx4 | 16673 | -0.356 | -0.3605 | Yes |
| 38 | Hmox2 | 16824 | -0.368 | -0.3425 | Yes |
| 39 | Sod1 | 17704 | -0.442 | -0.3571 | Yes |
| 40 | Ftl1 | 17815 | -0.457 | -0.3308 | Yes |
| 41 | Ndufa6 | 18050 | -0.490 | -0.3085 | Yes |
| 42 | Lsp1 | 18207 | -0.512 | -0.2807 | Yes |
| 43 | Cdkn2d | 18254 | -0.522 | -0.2464 | Yes |
| 44 | Lamtor5 | 18264 | -0.524 | -0.2101 | Yes |
| 45 | Hhex | 18338 | -0.537 | -0.1762 | Yes |
| 46 | Cat | 19042 | -0.748 | -0.1602 | Yes |
| 47 | Atox1 | 19256 | -0.984 | -0.1022 | Yes |
| 48 | Prdx2 | 19306 | -1.493 | 0.0001 | Yes |
