Details for gene set HALLMARK_PI3K_AKT_MTOR

Table: GSEA Results Summary

Dataset	MEP.MEP.mega_Pheno.cls #Group1_versus_Group4.MEP.mega_Pheno.cls #Group1_versus_Group4_repos
Phenotype	MEP.mega_Pheno.cls#Group1_versus_Group4_repos
Upregulated in class	0
GeneSet	HALLMARK_PI3K_AKT_MTOR_SIGNALING
Enrichment Score (ES)	0.18098338
Normalized Enrichment Score (NES)	0.7729442
Nominal p-value	0.8079208
FDR q-value	0.94314253
FWER p-Value	1.0

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Prkcb	105	0.832	0.0293	Yes
2	Trib3	299	0.684	0.0479	Yes
3	Ralb	482	0.611	0.0640	Yes
4	Il4	610	0.577	0.0816	Yes
5	Hsp90b1	1594	0.420	0.0480	Yes
6	Tsc2	2349	0.350	0.0234	Yes
7	Plcb1	2431	0.343	0.0335	Yes
8	Pikfyve	2858	0.311	0.0244	Yes
9	Mknk2	2989	0.305	0.0304	Yes
10	Sla	3006	0.304	0.0422	Yes
11	Traf2	3016	0.302	0.0544	Yes
12	Mapk8	3095	0.296	0.0628	Yes
13	Mknk1	3120	0.295	0.0739	Yes
14	Cdk2	3189	0.290	0.0825	Yes
15	Prkar2a	3287	0.283	0.0892	Yes
16	Fgf17	3392	0.276	0.0954	Yes
17	Nfkbib	3567	0.267	0.0975	Yes
18	Smad2	3661	0.259	0.1035	Yes
19	Sfn	3762	0.254	0.1089	Yes
20	Actr2	3803	0.251	0.1173	Yes
21	Actr3	3914	0.244	0.1218	Yes
22	Eif4e	3981	0.240	0.1284	Yes
23	Nck1	4235	0.229	0.1248	Yes
24	Mapkap1	4245	0.228	0.1339	Yes
25	Prkaa2	4248	0.228	0.1434	Yes
26	Ptpn11	4431	0.219	0.1431	Yes
27	Ube2n	4575	0.211	0.1444	Yes
28	Calr	4802	0.199	0.1410	Yes
29	Vav3	4888	0.195	0.1447	Yes
30	Plcg1	4930	0.193	0.1507	Yes
31	Nod1	5028	0.189	0.1536	Yes
32	Ppp2r1b	5153	0.185	0.1548	Yes
33	Grb2	5162	0.184	0.1621	Yes
34	Cltc	5255	0.179	0.1648	Yes
35	Cdk1	5277	0.178	0.1712	Yes
36	Akt1	5369	0.173	0.1737	Yes
37	Cab39	5461	0.168	0.1760	Yes
38	Rptor	5573	0.162	0.1770	Yes
39	Ripk1	5802	0.150	0.1714	Yes
40	Ywhab	5914	0.144	0.1716	Yes
41	Raf1	5962	0.142	0.1751	Yes
42	Map2k3	5964	0.142	0.1810	Yes
43	Irak4	6920	0.104	0.1356	No
44	Atf1	7065	0.097	0.1322	No
45	Ube2d3	7192	0.091	0.1295	No
46	Arf1	7322	0.085	0.1263	No
47	Rps6ka3	7680	0.069	0.1106	No
48	Pik3r3	7757	0.066	0.1094	No
49	Pten	7779	0.064	0.1110	No
50	Mapk1	7915	0.058	0.1064	No
51	Pla2g12a	8542	0.032	0.0751	No
52	Rit1	8567	0.032	0.0752	No
53	Cdkn1a	8757	0.023	0.0663	No
54	Acaca	8860	0.019	0.0618	No
55	Rps6ka1	8865	0.019	0.0624	No
56	Map3k7	9008	0.013	0.0555	No
57	Mapk9	9651	-0.010	0.0225	No
58	Gsk3b	9720	-0.013	0.0195	No
59	Tiam1	9970	-0.025	0.0076	No
60	Lck	10027	-0.029	0.0059	No
61	Pdk1	10182	-0.036	-0.0007	No
62	Cab39l	10215	-0.037	-0.0008	No
63	Cxcr4	10285	-0.040	-0.0027	No
64	Myd88	10299	-0.041	-0.0016	No
65	Ap2m1	10377	-0.043	-0.0039	No
66	Prkag1	10431	-0.045	-0.0047	No
67	Cdkn1b	10549	-0.051	-0.0087	No
68	Tbk1	10599	-0.053	-0.0090	No
69	Camk4	10649	-0.055	-0.0093	No
70	Dusp3	11933	-0.113	-0.0713	No
71	Itpr2	12963	-0.157	-0.1184	No
72	Map2k6	13279	-0.170	-0.1276	No
73	E2f1	13424	-0.175	-0.1278	No
74	Gna14	13541	-0.181	-0.1263	No
75	Pin1	13634	-0.184	-0.1234	No
76	Ddit3	13716	-0.188	-0.1197	No
77	Pitx2	13971	-0.200	-0.1245	No
78	Adcy2	14040	-0.204	-0.1196	No
79	Dapp1	14616	-0.231	-0.1398	No
80	Mapk10	14787	-0.241	-0.1386	No
81	Pak4	14803	-0.242	-0.1292	No
82	Arhgdia	14880	-0.246	-0.1229	No
83	Rac1	15118	-0.257	-0.1244	No
84	Ecsit	15194	-0.262	-0.1174	No
85	Stat2	15246	-0.266	-0.1089	No
86	Csnk2b	15499	-0.278	-0.1104	No
87	Cdk4	16469	-0.341	-0.1466	No
88	Tnfrsf1a	16569	-0.348	-0.1371	No
89	Akt1s1	16781	-0.364	-0.1329	No
90	Grk2	16880	-0.372	-0.1224	No
91	Pfn1	17092	-0.391	-0.1171	No
92	Arpc3	17837	-0.459	-0.1366	No
93	Ppp1ca	18032	-0.486	-0.1263	No
94	Il2rg	18205	-0.512	-0.1139	No
95	Slc2a1	18900	-0.673	-0.1218	No
96	Them4	19041	-0.747	-0.0979	No
97	Sqstm1	19048	-0.750	-0.0668	No
98	Cfl1	19060	-0.760	-0.0356	No
99	Hras	19294	-1.156	0.0007	No