Details for gene set HALLMARK_P53

Table: GSEA Results Summary

Dataset	MEP.MEP.mega_Pheno.cls #Group1_versus_Group4.MEP.mega_Pheno.cls #Group1_versus_Group4_repos
Phenotype	MEP.mega_Pheno.cls#Group1_versus_Group4_repos
Upregulated in class	3
GeneSet	HALLMARK_P53_PATHWAY
Enrichment Score (ES)	-0.28097585
Normalized Enrichment Score (NES)	-1.1032962
Nominal p-value	0.33264032
FDR q-value	0.54784805
FWER p-Value	0.962

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Trib3	299	0.684	-0.0021	No
2	Fos	302	0.683	0.0114	No
3	Tgfa	339	0.659	0.0225	No
4	Dram1	367	0.646	0.0339	No
5	F2r	448	0.619	0.0420	No
6	Jun	632	0.572	0.0438	No
7	Zmat3	652	0.565	0.0540	No
8	Blcap	737	0.546	0.0604	No
9	Baiap2	807	0.529	0.0672	No
10	Ralgds	864	0.522	0.0747	No
11	Ddit4	1243	0.462	0.0640	No
12	Plk2	1260	0.460	0.0723	No
13	Cdkn2aip	1307	0.453	0.0789	No
14	Ccp110	1478	0.432	0.0786	No
15	Elp1	1767	0.398	0.0714	No
16	Coq8a	1957	0.382	0.0691	No
17	Fgf13	1983	0.379	0.0753	No
18	Ip6k2	2045	0.372	0.0794	No
19	Hbegf	2129	0.365	0.0823	No
20	Atf3	2561	0.334	0.0664	No
21	Mknk2	2989	0.305	0.0501	No
22	App	3023	0.302	0.0544	No
23	Sp1	3133	0.294	0.0545	No
24	Polh	3237	0.287	0.0548	No
25	Hmox1	3717	0.256	0.0348	No
26	Sfn	3762	0.254	0.0375	No
27	Abat	3822	0.250	0.0394	No
28	Jag2	4080	0.235	0.0306	No
29	Zfp365	4233	0.229	0.0272	No
30	Aen	4440	0.219	0.0208	No
31	Cdh13	4774	0.201	0.0073	No
32	Pmm1	4876	0.196	0.0059	No
33	Pvt1	5103	0.185	-0.0022	No
34	Rchy1	5325	0.175	-0.0103	No
35	Tob1	5332	0.175	-0.0072	No
36	Csrnp2	5438	0.169	-0.0093	No
37	Xpc	5445	0.169	-0.0063	No
38	Fdxr	5582	0.161	-0.0102	No
39	Pcna	5679	0.156	-0.0122	No
40	Dgka	6106	0.134	-0.0318	No
41	Ccnk	6157	0.132	-0.0318	No
42	Rb1	6163	0.132	-0.0294	No
43	Osgin1	6190	0.131	-0.0282	No
44	Kif13b	6240	0.129	-0.0282	No
45	Irag2	6247	0.128	-0.0260	No
46	Gls2	6261	0.128	-0.0241	No
47	Fbxw7	6626	0.118	-0.0408	No
48	Ctsd	6642	0.118	-0.0393	No
49	Hspa4l	6648	0.117	-0.0372	No
50	Wwp1	6660	0.117	-0.0355	No
51	Ctsf	6786	0.111	-0.0398	No
52	Stom	6819	0.109	-0.0393	No
53	Mdm2	6858	0.107	-0.0392	No
54	Ninj1	6885	0.106	-0.0385	No
55	Ak1	6992	0.101	-0.0420	No
56	Foxo3	7174	0.092	-0.0497	No
57	Notch1	7221	0.090	-0.0503	No
58	Txnip	7330	0.084	-0.0543	No
59	Sesn1	7450	0.079	-0.0589	No
60	H2ac25	7460	0.079	-0.0578	No
61	Zbtb16	7513	0.077	-0.0590	No
62	Tm7sf3	7548	0.075	-0.0593	No
63	Epha2	7580	0.073	-0.0595	No
64	Slc3a2	7712	0.068	-0.0650	No
65	S100a4	7870	0.060	-0.0720	No
66	Klf4	7896	0.058	-0.0722	No
67	Ercc5	7929	0.057	-0.0727	No
68	St14	8036	0.052	-0.0772	No
69	Eps8l2	8145	0.048	-0.0819	No
70	Cdkn1a	8757	0.023	-0.1134	No
71	Bax	8801	0.021	-0.1152	No
72	Apaf1	8966	0.014	-0.1235	No
73	Itgb4	8981	0.013	-0.1240	No
74	Btg1	9176	0.005	-0.1340	No
75	Vwa5a	9640	-0.009	-0.1581	No
76	Tspyl2	9761	-0.014	-0.1641	No
77	Ier5	9832	-0.018	-0.1674	No
78	Ccng1	9895	-0.021	-0.1702	No
79	Fuca1	9917	-0.022	-0.1709	No
80	Btg2	10015	-0.028	-0.1754	No
81	Slc35d1	10109	-0.032	-0.1796	No
82	Perp	10388	-0.044	-0.1933	No
83	Sertad3	10412	-0.045	-0.1936	No
84	Cdkn2a	10583	-0.052	-0.2014	No
85	Triap1	10653	-0.055	-0.2040	No
86	Mxd4	10706	-0.058	-0.2055	No
87	Slc19a2	10957	-0.069	-0.2172	No
88	Rab40c	10980	-0.070	-0.2170	No
89	Pidd1	11042	-0.073	-0.2187	No
90	Ccnd2	11143	-0.077	-0.2224	No
91	Rhbdf2	11187	-0.079	-0.2231	No
92	Rrp8	11208	-0.080	-0.2226	No
93	Tnfsf9	11265	-0.083	-0.2239	No
94	Sphk1	11361	-0.087	-0.2271	No
95	Cyfip2	11422	-0.090	-0.2285	No
96	Sdc1	11542	-0.096	-0.2328	No
97	Nol8	11608	-0.098	-0.2342	No
98	Bmp2	11796	-0.107	-0.2419	No
99	Socs1	11883	-0.111	-0.2442	No
100	Nudt15	11980	-0.115	-0.2469	No
101	Def6	12005	-0.116	-0.2459	No
102	Plk3	12128	-0.121	-0.2499	No
103	Tax1bp3	12140	-0.122	-0.2480	No
104	Mapkapk3	12175	-0.123	-0.2474	No
105	Hdac3	12188	-0.124	-0.2455	No
106	Rap2b	12217	-0.125	-0.2445	No
107	H1f2	12405	-0.132	-0.2517	No
108	Slc7a11	12682	-0.144	-0.2633	No
109	Abcc5	12818	-0.150	-0.2674	No
110	Ppm1d	12961	-0.156	-0.2717	No
111	Ephx1	12990	-0.157	-0.2700	No
112	Zfp36l1	13070	-0.161	-0.2710	No
113	Ankra2	13173	-0.166	-0.2730	No
114	Hexim1	13199	-0.167	-0.2710	No
115	Plxnb2	13241	-0.169	-0.2698	No
116	Rad9a	13303	-0.171	-0.2696	No
117	Traf4	13375	-0.172	-0.2699	No
118	Cd81	13474	-0.177	-0.2715	No
119	Rnf19b	13504	-0.179	-0.2695	No
120	Ptpn14	13549	-0.181	-0.2682	No
121	Pom121	13638	-0.184	-0.2692	No
122	Ppp1r15a	13665	-0.185	-0.2669	No
123	Prmt2	13681	-0.187	-0.2639	No
124	Rxra	13689	-0.187	-0.2606	No
125	Ddit3	13716	-0.188	-0.2582	No
126	Upp1	13873	-0.195	-0.2625	No
127	Steap3	13925	-0.198	-0.2613	No
128	Ada	14009	-0.202	-0.2616	No
129	Trp63	14070	-0.206	-0.2607	No
130	Sat1	14352	-0.217	-0.2711	No
131	Dcxr	14425	-0.221	-0.2705	No
132	Rad51c	14438	-0.222	-0.2667	No
133	Rrad	14487	-0.225	-0.2648	No
134	Cdk5r1	14576	-0.230	-0.2648	No
135	Il1a	14593	-0.230	-0.2611	No
136	Tpd52l1	14682	-0.235	-0.2610	No
137	Irak1	14801	-0.242	-0.2624	No
138	Tsc22d1	14887	-0.247	-0.2620	No
139	Hint1	14890	-0.247	-0.2572	No
140	Nupr1	14977	-0.250	-0.2567	No
141	Ddb2	15011	-0.252	-0.2535	No
142	Pdgfa	15075	-0.256	-0.2517	No
143	Trp53	15173	-0.261	-0.2516	No
144	Ptpre	15329	-0.271	-0.2543	No
145	Fam162a	15485	-0.277	-0.2569	No
146	Retsat	15504	-0.279	-0.2524	No
147	Ier3	15663	-0.289	-0.2549	No
148	Acvr1b	15865	-0.300	-0.2595	No
149	Cd82	15876	-0.301	-0.2540	No
150	Mxd1	16095	-0.317	-0.2592	No
151	Wrap73	16269	-0.328	-0.2617	No
152	Tgfb1	16301	-0.329	-0.2568	No
153	Tcn2	16544	-0.346	-0.2626	No
154	Vamp8	16555	-0.347	-0.2562	No
155	Bak1	17029	-0.384	-0.2734	Yes
156	Gadd45a	17123	-0.394	-0.2704	Yes
157	Pitpnc1	17218	-0.401	-0.2674	Yes
158	Fas	17219	-0.401	-0.2595	Yes
159	Tap1	17323	-0.411	-0.2567	Yes
160	H2aj	17333	-0.412	-0.2490	Yes
161	Tprkb	17351	-0.414	-0.2417	Yes
162	Procr	17612	-0.434	-0.2467	Yes
163	Abhd4	17900	-0.468	-0.2524	Yes
164	Casp1	18083	-0.494	-0.2522	Yes
165	Rpl36	18187	-0.509	-0.2475	Yes
166	Ndrg1	18191	-0.510	-0.2375	Yes
167	Trafd1	18208	-0.513	-0.2282	Yes
168	Sec61a1	18214	-0.514	-0.2183	Yes
169	Ldhb	18323	-0.535	-0.2134	Yes
170	Dnttip2	18436	-0.556	-0.2082	Yes
171	Vdr	18668	-0.605	-0.2083	Yes
172	Ei24	18745	-0.628	-0.1998	Yes
173	Gm2a	18748	-0.629	-0.1875	Yes
174	S100a10	18855	-0.658	-0.1800	Yes
175	Rack1	18859	-0.659	-0.1671	Yes
176	Ccnd3	18873	-0.663	-0.1546	Yes
177	Cgrrf1	18878	-0.666	-0.1416	Yes
178	Rpl18	18926	-0.685	-0.1305	Yes
179	Phlda3	18940	-0.688	-0.1176	Yes
180	Cebpa	18971	-0.709	-0.1051	Yes
181	Klk8	19027	-0.738	-0.0933	Yes
182	Iscu	19156	-0.835	-0.0835	Yes
183	Rps27l	19170	-0.853	-0.0673	Yes
184	Rps12	19180	-0.860	-0.0507	Yes
185	Prkab1	19184	-0.863	-0.0338	Yes
186	Ifi30	19189	-0.868	-0.0168	Yes
187	Hras	19294	-1.156	0.0007	Yes